… however useful the words may have been in the past, they have now become handicaps to the further development of knowledge. Words like botany and zoology imply that plants and animals are quite different things. … But the differences rapidly become blurred when we start looking at the world through a microscope. … The similarities between plants and animals became more important than their differences with the discoveries that both were built up of cells, had sexual reproduction,… nutrition and respiration … and with the development of evolutionary theory.

… just as the astronomer, the physicist, the geologist, or other student of objective science looks about in the world of sense, so, not metaphorically speaking but literally, the mind of the mathematician goes forth in the universe of logic in quest of the things that are there; exploring the heights and depths for facts—ideas, classes, relationships, implications, and the rest; observing the minute and elusive with the powerful microscope of his Infinitesimal Analysis; observing the elusive and vast with the limitless telescope of his Calculus of the Infinite; making guesses regarding the order and internal harmony of the data observed and collocated; testing the hypotheses, not merely by the complete induction peculiar to mathematics, but, like his colleagues of the outer world, resorting also to experimental tests and incomplete induction; frequently finding it necessary, in view of unforeseen disclosures, to abandon one hopeful hypothesis or to transform it by retrenchment or by enlargement:—thus, in his own domain, matching, point for point, the processes, methods and experience familiar to the devotee of natural science.

… the United States was not built by those who waited and rested and wished to look behind them. This country was conquered by those who moved forward, and so will space.

…at the stars,
Which are the brain of heaven, he look’d, and sank.
Around the ancient track marched, rank on rank,
The army of unalterable law.

...conscience looks backwards and judges past actions, inducing that kind of dissatisfaction, which if weak we call regret, and if severe remorse.

…reality is a system, completely ordered and fully intelligible, with which thought in its advance is more and more identifying itself. We may look at the growth of knowledge … as an attempt by our mind to return to union with things as they are in their ordered wholeness…. and if we take this view, our notion of truth is marked out for us. Truth is the approximation of thought to reality … Its measure is the distance thought has travelled … toward that intelligible system … The degree of truth of a particular proposition is to be judged in the first instance by its coherence with experience as a whole, ultimately by its coherence with that further whole, all comprehensive and fully articulated, in which thought can come to rest.

’Tis a short sight to limit our faith in laws to those of gravity, of chemistry, of botany, and so forth. Those laws do not stop where our eyes lose them, but push the same geometry and chemistry up into the invisible plane of social and rational life, so that, look where we will, in a boy's game, or in the strifes of races, a perfect reaction, a perpetual judgment keeps watch and ward.

“Advance, ye mates! Cross your lances full before me. Well done! Let me touch the axis.” So saying, with extended arm, he grasped the three level, radiating lances at their crossed centre; while so doing, suddenly and nervously twitched them; meanwhile, glancing intently from Starbuck to Stubb; from Stubb to Flask. It seemed as though, by some nameless, interior volition, he would fain have shocked into them the same fiery emotion accumulated within the Leyden jar of his own magnetic life. The three mates quailed before his strong, sustained, and mystic aspect. Stubb and Flask looked sideways from him; the honest eye of Starbuck fell downright.
“In vain!&rsdquo; cried Ahab; “but, maybe, ’tis well. For did ye three but once take the full-forced shock, then mine own electric thing, that had perhaps expired from out me. Perchance, too, it would have dropped ye dead.…”
[Commentary by Henry Schlesinger: Electricity—mysterious and powerful as it seemed at the time—served as a perfect metaphor for Captain Ahab’s primal obsession and madness, which he transmits through the crew as if through an electrical circuit in Moby-Dick.]

“Cradle to Cradle” is in counterpoint to “Cradle to Grave.” It basically says that if we look at everything as a take, make and waste system, then it’s a one-way system. Whereas If we think about things having multiple lives, cradle to cradle, we could design things that can go back to either nature or back to industry forever.

“Expect surprises!” should be the watchword of all scientists who try to look beyond the fashions of the day.

“Talent is a long patience.” We must look on what we wish to express long enough and with enough attention to discover an aspect that has not been seen and portrayed by another. There is, in everything, something unexplored, because we always use our eyes only with the recollection of what has been thought before on the subject we are contemplating.

[An outsider views a scientist] as a type of unscrupulous opportunist: he appears as a realist, insofar as he seeks to describe the world independent of the act of perception; as idealist insofar as he looks upon the concepts and theories as the free inventions of the human spirit (not logically derivable from that which is empirically given); as positivist insofar as he considers his concepts and theories justified only to the extent to which they furnish a logical representation of relations among sense experiences. He may even appear as Platonist or Pythagorean insofar as he considers the viewpoint of logical simplicity as an indispensable and effective tool of his research.

[Experimental Physicist] Phys. I cannot imagine myself perceiving non-Euclidean space!
Math. Look at the reflection of the room in a polished doorknob, and imagine yourself one of the actors in what you see going on there.

[Geology] may be looked upon as the history of the earth’s changes during preparation for the reception of organized beings, a history, which has all the character of a great epic.

[Ignorance] of the principle of conservation of energy … does not prevent inventors without background from continually putting forward perpetual motion machines… Also, such persons undoubtedly have their exact counterparts in the fields of art, finance, education, and all other departments of human activity… persons who are unwilling to take the time and to make the effort required to find what the known facts are before they become the champions of unsupported opinions—people who take sides first and look up facts afterward when the tendency to distort the facts to conform to the opinions has become well-nigh irresistible.

[In childhood, to overcome fear, the] need took me back again and again to a sycamore tree rising from the earth at the edge of a ravine. It was a big, old tree that had grown out over the ravine, so that when you climbed it, you looked straight down fifty feet or more. Every time I climbed that tree, I forced myself to climb to the last possible safe limb and then look down. Every time I did it, I told myself I’d never do it again. But I kept going back because it scared me and I had to know I could overcome that.

[In my early youth, walking with my father,] “See that bird?” he says. “It’s a Spencer’s warbler.” (I knew he didn’t know the real name.) “Well, in Italian, it’s a Chutto Lapittida. In Portuguese, it’s a Bom da Peida. In Chinese, it’s a Chung-long-tah, and in Japanese, it’s a Katano Tekeda. You can know the name of that bird in all the languages of the world, but when you’re finished, you’ll know absolutely nothing whatever about the bird. You’ll only know about humans in different places, and what they call the bird. So let’s look at the bird and see what it’s doing—that’s what counts.” (I learned very early the difference between knowing the name of something and knowing something.)

[In space] the stars don’t look bigger, but they do look brighter.

[L]et us not overlook the further great fact, that not only does science underlie sculpture, painting, music, poetry, but that science is itself poetic. The current opinion that science and poetry are opposed is a delusion. … On the contrary science opens up realms of poetry where to the unscientific all is a blank. Those engaged in scientific researches constantly show us that they realize not less vividly, but more vividly, than others, the poetry of their subjects. Whoever will dip into Hugh Miller’s works on geology, or read Mr. Lewes's “Seaside Studies,” will perceive that science excites poetry rather than extinguishes it. And whoever will contemplate the life of Goethe will see that the poet and the man of science can co-exist in equal activity. Is it not, indeed, an absurd and almost a sacrilegious belief that the more a man studies Nature the less he reveres it? Think you that a drop of water, which to the vulgar eye is but a drop of water, loses anything in the eye of the physicist who knows that its elements are held together by a force which, if suddenly liberated, would produce a flash of lightning? Think you that what is carelessly looked upon by the uninitiated as a mere snow-flake, does not suggest higher associations to one who has seen through a microscope the wondrously varied and elegant forms of snow-crystals? Think you that the rounded rock marked with parallel scratches calls up as much poetry in an ignorant mind as in the mind of a geologist, who knows that over this rock a glacier slid a million years ago? The truth is, that those who have never entered upon scientific pursuits know not a tithe of the poetry by which they are surrounded. Whoever has not in youth collected plants and insects, knows not half the halo of interest which lanes and hedge-rows can assume. Whoever has not sought for fossils, has little idea of the poetical associations that surround the places where imbedded treasures were found. Whoever at the seaside has not had a microscope and aquarium, has yet to learn what the highest pleasures of the seaside are. Sad, indeed, is it to see how men occupy themselves with trivialities, and are indifferent to the grandest phenomena—care not to understand the architecture of the Heavens, but are deeply interested in some contemptible controversy about the intrigues of Mary Queen of Scots!—are learnedly critical over a Greek ode, and pass by without a glance that grand epic written by the finger of God upon the strata of the Earth!

[Microscopic] evidence cannot be presented ad populum. What is seen with the microscope depends not only upon the instrument and the rock-section, but also upon the brain behind the eye of the observer. Each of us looks at a section with the accumulated experience of his past study. Hence the veteran cannot make the novice see with his eyes; so that what carries conviction to the one may make no appeal to the other. This fact does not always seem to be sufficiently recognized by geologists at large.

[My Book] will endeavour to establish the principle[s] of reasoning in ... [geology]; and all my geology will come in as illustration of my views of those principles, and as evidence strengthening the system necessarily arising out of the admission of such principles, which... are neither more nor less than that no causes whatever have from the earliest time to which we can look back, to the present, ever acted, but those now acting; and that they never acted with different degrees of energy from that which they now exert.

[On the future of Chemistry:] Chemistry is not the preservation hall of old jazz that it sometimes looks like. We cannot know what may happen tomorrow. Someone may oxidize mercury (II), francium (I), or radium (II). A mineral in Nova Scotia may contain an unsaturated quark per 1020 nucleons. (This is still 6000 per gram.) We may pick up an extraterrestrial edition of Chemical Abstracts. The universe may be a 4-dimensional soap bubble in an 11-dimensional space as some supersymmetry theorists argued in May of 1983. Who knows?

[Otto Struve] made the remark once that he never looked at the spectrum of a star, any star, where he didn’t find something important to work on.

[The octopus has] an amazing skin, because there are up to 20 million of these chromatophore pigment cells and to control 20 million of anything is going to take a lot of processing power. ... These animals have extraordinarily large, complicated brains to make all this work. ... And what does this mean about the universe and other intelligent life? The building blocks are potentially there and complexity will arise. Evolution is the force that's pushing that. I would expect, personally, a lot of diversity and a lot of complicated structures. It may not look like us, but my personal view is that there is intelligent life out there.

[Using mice as model systems for genetic engineering in biomedicine, instead of bacterial or yeast systems matters because] this transition will have as big an impact on the future of biology as the shift from printing presses to video technology has had on pop culture. A mouse-based world looks and feels different from one viewed through microorganisms.

[Watching natural history programs] brings a solace you can’t describe in words. It’s because we’re part of it fundamentally…. In moments of great grief, that’s where you look and immerse yourself. You realise you are not immortal, you are not a god, you are part of the natural world and you come to accept that.

[When I was a child] I grew up in Brooklyn, New York, and I was a street kid. … [T]here was one aspect of that environment that, for some reason, struck me as different, and that was the stars. … I could tell they were lights in the sky, but that wasn’t an explanation. I mean, what were they? Little electric bulbs on long black wires, so you couldn’t see what they were held up by? What were they? … My mother said to me, "Look, we’ve just got you a library card … get out a book and find the answer.” … It was in there. It was stunning. The answer was that the Sun was a star, except very far away. … The dazzling idea of a universe vast beyond imagining swept over me. … I sensed awe.

Strictly Germ-proof

The Antiseptic Baby and the Prophylactic Pup
Were playing in the garden when the Bunny gamboled up;
They looked upon the Creature with a loathing undisguised;—
It wasn't Disinfected and it wasn't Sterilized.

They said it was a Microbe and a Hotbed of Disease;
They steamed it in a vapor of a thousand-odd degrees;
They froze it in a freezer that was cold as Banished Hope
And washed it in permanganate with carbolated soap.

In sulphurated hydrogen they steeped its wiggly ears;
They trimmed its frisky whiskers with a pair of hard-boiled shears;
They donned their rubber mittens and they took it by the hand
And elected it a member of the Fumigated Band.

There's not a Micrococcus in the garden where they play;
They bathe in pure iodoform a dozen times a day;
And each imbibes his rations from a Hygienic Cup—
The Bunny and the Baby and the Prophylactic Pup.

Der bis zur Vorrede, die ihn abweist, gelangte Leser hat das Buch für baares Geld gekauft und frägt, was ihn schadlos hält? – Meine letzte Zuflucht ist jetzt, ihn zu erinnern, daß er ein Buch, auch ohne es gerade zu lesen, doch auf mancherlei Art zu benutzen weiß. Es kann, so gut wie viele andere, eine Lücke seiner Bibliothek ausfüllen, wo es sich, sauber gebunden, gewiß gut ausnehmen wird. Oder auch er kann es seiner gelehrten Freundin auf die Toilette, oder den Theetisch legen. Oder endlich er kann ja, was gewiß das Beste von Allem ist und ich besonders rathe, es recensiren.
The reader who has got as far as the preface and is put off by that, has paid money for the book, and wants to know how he is to be compensated. My last refuge now is to remind him that he knows of various ways of using a book without precisely reading it. It can, like many another, fill a gap in his library, where, neatly bound, it is sure to look well. Or he can lay it on the dressing-table or tea-table of his learned lady friend. Or finally he can review it; this is assuredly the best course of all, and the one I specially advise.

Dogbert: So, Since Columbus is dead, you have no evidence that the earth is round.
Dilbert: Look. You can Ask Senator John Glenn. He orbited the earth when he was an astronaut.
Dogbert: So, your theory depends on the honesty of politicians.
Dilbert: Yes... no, wait...

Il est impossible de contempler le spectacle de l’univers étoilé sans se demander comment il s’est formé: nous devions peut-être attendre pour chercher une solution que nous ayons patiemment rassemblé les éléments …mais si nous étions si raisonnables, si nous étions curieux sans impatience, il est probable que nous n’avions jamais créé la Science et que nous nous serions toujours contentés de vivre notre petite vie. Notre esprit a donc reclamé impérieusement cette solution bien avant qu’elle fut mûre, et alors qu’il ne possédait que de vagues lueurs, lui permettant de la deviner plutôt que de l’attendre.
It is impossible to contemplate the spectacle of the starry universe without wondering how it was formed: perhaps we ought to wait, and not look for a solution until have patiently assembled the elements … but if we were so reasonable, if we were curious without impatience, it is probable we would never have created Science and we would always have been content with a trivial existence. Thus the mind has imperiously laid claim to this solution long before it was ripe, even while perceived in only faint glimmers—allowing us to guess a solution rather than wait for it.

Jobs: I look at myself as an artist if anything. Sort of a trapeze artist.
Levy: With or without a net?
Jobs: Without.

Lepidoptera are for children to play with, pretty to look at, so some think. Give me the Coleoptera, and the kings of the Coleoptera are the beetles! Lepidoptera and Neuroptera for little folks; Coleoptera for men, sir!

Question: Explain how to determine the time of vibration of a given tuning-fork, and state what apparatus you would require for the purpose.
Answer: For this determination I should require an accurate watch beating seconds, and a sensitive ear. I mount the fork on a suitable stand, and then, as the second hand of my watch passes the figure 60 on the dial, I draw the bow neatly across one of its prongs. I wait. I listen intently. The throbbing air particles are receiving the pulsations; the beating prongs are giving up their original force; and slowly yet surely the sound dies away. Still I can hear it, but faintly and with close attention; and now only by pressing the bones of my head against its prongs. Finally the last trace disappears. I look at the time and leave the room, having determined the time of vibration of the common “pitch” fork. This process deteriorates the fork considerably, hence a different operation must be performed on a fork which is only lent.

Si monumentum requiris circumspice
Reader, if you seek his monument, look about you.

The Annotated Alice, of course, does tie in with math, because Lewis Carroll was, as you know, a professional mathematician. So it wasn’t really too far afield from recreational math, because the two books are filled with all kinds of mathematical jokes. I was lucky there in that I really didn’t have anything new to say in The Annotated Alice because I just looked over the literature and pulled together everything in the form of footnotes. But it was a lucky idea because that’s been the best seller of all my books.

A biologist, if he wishes to know how many toes a cat has, does not "frame the hypothesis that the number of feline digital extremities is 4, or 5, or 6," he simply looks at a cat and counts. A social scientist prefers the more long-winded expression every time, because it gives an entirely spurious impression of scientificness to what he is doing.

A book is a mirror: when a monkey looks in, no apostle can look out.

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A cynic is a man who, when he smells flowers, looks around for a coffin.

A donkey looks to me like a horse translated into Dutch.

A fox looked at his shadow at sunrise and said, “I will have a camel for lunch today.” And all morning he went about looking for camels. But at noon he saw his shadow again - and he said, “A mouse will do.”

A historical fact is rather like the flamingo that Alice in Wonderland tried to use as a croquet mallet. As soon as she got its neck nicely straightened out and was ready to hit the ball, it would turn and look at her with a puzzled expression, and any biographer knows that what is called a “fact” has a way of doing the same.

A hundred years ago, Auguste Compte, … a great philosopher, said that humans will never be able to visit the stars, that we will never know what stars are made out of, that that's the one thing that science will never ever understand, because they're so far away. And then, just a few years later, scientists took starlight, ran it through a prism, looked at the rainbow coming from the starlight, and said: “Hydrogen!” Just a few years after this very rational, very reasonable, very scientific prediction was made, that we'll never know what stars are made of.

A large number of areas of the brain are involved when viewing equations, but when one looks at a formula rated as beautiful it activates the emotional brain—the medial orbito-frontal cortex—like looking at a great painting or listening to a piece of music. … Neuroscience can’t tell you what beauty is, but if you find it beautiful the medial orbito-frontal cortex is likely to be involved; you can find beauty in anything.

A lot of people ask, “Do you think humans are parasites?” It’s an interesting idea and one worth thinking about. People casually refer to humanity as a virus spreading across the earth. In fact, we do look like some strange kind of bio-film spreading across the landscape. A good metaphor? If the biosphere is our host, we do use it up for our own benefit. We do manipulate it. We alter the flows and fluxes of elements like carbon and nitrogen to benefit ourselves—often at the expense of the biosphere as a whole. If you look at how coral reefs or tropical forests are faring these days, you’ll notice that our host is not doing that well right now. Parasites are very sophisticated; parasites are highly evolved; parasites are very successful, as reflected in their diversity. Humans are not very good parasites. Successful parasites do a very good job of balancing—using up their hosts and keeping them alive. It’s all a question of tuning the adaptation to your particular host. In our case, we have only one host, so we have to be particularly careful.

A man should look for what is, and not for what he thinks should be.

A man who has once looked with the archaeological eye will never see quite normally. He will be wounded by what other men call trifles. It is possible to refine the sense of time until an old shoe in the bunch grass or a pile of nineteenth century beer bottles in an abandoned mining town tolls in one’s head like a hall clock.

A man’s value to the community depends primarily on how far his feelings, thoughts, and actions are directed towards promoting the good of his fellows. We call him good or bad according to how he stands in this matter. It looks at first sight as if our estimate of a man depended entirely on his social qualities.

A metallurgist is an expert who can look at a platinum blonde and tell whether she is virgin metal or common ore.

A mile and a half from town, I came to a grove of tall cocoanut trees, with clean, branchless stems reaching straight up sixty or seventy feet and topped with a spray of green foliage sheltering clusters of cocoanuts—not more picturesque than a forest of colossal ragged parasols, with bunches of magnified grapes under them, would be. I once heard a grouty northern invalid say that a cocoanut tree might be poetical, possibly it was; but it looked like a feather-duster struck by lightning. I think that describes it better than a picture—and yet, without any question, there is something fascinating about a cocoanut tree—and graceful, too.

A moment’s consideration of this case shows what a really great advance in the theory and practise of breeding has been obtained through the discovery of Mendel’s law. What a puzzle this case would have presented to the biologist ten years ago! Agouti crossed with chocolate gives in the second filial generation (not in the first) four varieties, viz., agouti, chocolate, black and cinnamon. We could only have shaken our heads and looked wise (or skeptical).
Then we had no explanation to offer for such occurrences other than the “instability of color characters under domestication,” the “effects of inbreeding,” “maternal impressions.” Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel’s law.

A monument to Newton! a monument to Shakespeare! Look up to Heaven—look into the Human Heart. Till the planets and the passions–the affections and the fixed stars are extinguished—their names cannot die.

A practical botanist will distinguish, at the first glance, the plant of different quarters of the globe, and yet will be at a loss to tell by what mark he detects them. There is, I know not what look—sinister, dry, obscure, in African plants; superb and elevated in the Asiatic; smooth and cheerful in the American; stunted and indurated in the Alpine.

A psychiatrist is a man who goes to the Folies-Bergère and looks at the audience.

A scientist works largely by intuition. Given enough experience, a scientist examining a problem can leap to an intuition as to what the solution ‘should look like.’ ... Science is ultimately based on insight, not logic.

A small cabin stands in the Glacier Peak Wilderness, about a hundred yards off a trail that crosses the Cascade Range. In midsummer, the cabin looked strange in the forest. It was only twelve feet square, but it rose fully two stories and then had a high and steeply peaked roof. From the ridge of the roof, moreover, a ten-foot pole stuck straight up. Tied to the top of the pole was a shovel. To hikers shedding their backpacks at the door of the cabin on a cold summer evening—as the five of us did—it was somewhat unnerving to look up and think of people walking around in snow perhaps thirty-five feet above, hunting for that shovel, then digging their way down to the threshold.

A story about the Jack Spratts of medicine [was] told recently by Dr. Charles H. Best, co-discoverer of insulin. He had been invited to a conference of heart specialists in North America. On the eve of the meeting, out of respect for the fat-clogs-the-arteries theory, the delegates sat down to a special banquet served without fats. It was unpalatable but they all ate it as a duty. Next morning Best looked round the breakfast room and saw these same specialists—all in the 40-60 year old, coronary age group—happily tucking into eggs, bacon, buttered toast and coffee with cream.

All good intellects have repeated, since Bacon’s time, that there can be no real knowledge but that which is based on observed facts. This is incontestable, in our present advanced stage; but, if we look back to the primitive stage of human knowledge, we shall see that it must have been otherwise then. If it is true that every theory must be based upon observed facts, it is equally true that facts cannot be observed without the guidance of some theory. Without such guidance, our facts would be desultory and fruitless; we could not retain them: for the most part we could not even perceive them.

All of my life, I have been fascinated by the big questions that face us, and have tried to find scientific answers to them. If, like me, you have looked at the stars, and tried to make sense of what you see, you too have started to wonder what makes the universe exist.

All palaetiological sciences, all speculations which attempt to ascend from the present to the remote past, by the chain of causation, do also, by an inevitable consequence, urge us to look for the beginning of the state of things which we thus contemplate; but in none of these cases have men been able, by the aid of science, to arrive at a beginning which is homogeneous with the known course of events. The first origin of language, of civilization, of law and government, cannot be clearly made out by reasoning and research; and just as little, we may expect, will a knowledge of the origin of the existing and extinct species of plants and animals, be the result of physiological and geological investigation.

Although the ocean’s surface seems at first to be completely homogeneous, after half a month we began to differentiate various seas and even different parts of oceans by their characteristic shades. We were astonished to discover that, during an flight, you have to learn anew not only to look, but also to see. At first the finest nuances of color elude you, but gradually your vision sharpens and your color perception becomes richer, and the planet spreads out before you with all its indescribable beauty.

Alvarez seemed to care less about the way the picture in the puzzle would look, when everything fit together, than about the fun of looking for pieces that fit. He loved nothing more than doing something that everybody else thought impossible. His designs were clever, and usually exploited some little-known principle that everyone else had forgotten.

Amoeba has her picture in the book,
Proud Protozoon!—Yet beware of pride,
All she can do is fatten and divide;
She cannot even read, or sew, or cook…
The Worm can crawl
But has no eyes to look.
The Jelly-fish can swim
But lacks a bride.

Among all highly civilized peoples the golden age of art has always been closely coincident with the golden age of the pure sciences, particularly with mathematics, the most ancient among them.
This coincidence must not be looked upon as accidental, but as natural, due to an inner necessity. Just as art can thrive only when the artist, relieved of the anxieties of existence, can listen to the inspirations of his spirit and follow in their lead, so mathematics, the most ideal of the sciences, will yield its choicest blossoms only when life’s dismal phantom dissolves and fades away, when the striving after naked truth alone predominates, conditions which prevail only in nations while in the prime of their development.

An engineer passing a pond heard a frog say, “If you kiss me, I’ll turn into a beautiful princess.” He picked up the frog, looked at it, and put it in his pocket. The frog said, “Why didn’t you kiss me?” Replied the engineer, “Look, I’m an engineer. I don’t have time for a girlfriend, but a talking frog is cool.”

An evolution is a series of events that in itself as series is purely physical, — a set of necessary occurrences in the world of space and time. An egg develops into a chick; … a planet condenses from the fluid state, and develops the life that for millions of years makes it so wondrous a place. Look upon all these things descriptively, and you shall see nothing but matter moving instant after instant, each instant containing in its full description the necessity of passing over into the next. … But look at the whole appreciatively, historically, synthetically, as a musician listens to a symphony, as a spectator watches a drama. Now you shall seem to have seen, in phenomenal form, a story.

And as to the faculties of the mind, setting aside the arts grounded upon words, and especially that skill of proceeding upon generall, and infallible rules, called Science; which very few have, and but in few things; as being not a native faculty, born within us; nor attained, (as Prudence,) while we look after somewhat else.

And if one look through a Prism upon a white Object encompassed with blackness or darkness, the reason of the Colours arising on the edges is much the same, as will appear to one that shall a little consider it. If a black Object be encompassed with a white one, the Colours which appear through the Prism are to be derived from the Light of the white one, spreading into the Regions of the black, and therefore they appear in a contrary order to that, when a white Object is surrounded with black. And the same is to be understood when an Object is viewed, whose parts are some of them less luminous than others. For in the borders of the more and less luminous Parts, Colours ought always by the same Principles to arise from the Excess of the Light of the more luminous, and to be of the same kind as if the darker parts were black, but yet to be more faint and dilute.

And new philosophy calls all in doubt,
The Element of fire is quite put out;
The Sun is lost, and th’earth, and no mans wit
Can well direct him where to look for it.
And freely men confesse that this world’s spent,
When in the Planets, and the Firmament
They seeke so many new; and then see that this
Is crumbled out againe to his Atomies.
’Tis all in pieces, all cohaerence gone;
All just supply, and all Relation;
Prince, Subject, Father, Sonne, are things forgot,
For every man alone thinkes he hath got
To be a phoenix, and that then can bee
None of that kinde, of which he is, but hee.

And, notwithstanding a few exceptions, we do undoubtedly find that the most truly eminent men have had not only their affections, but also their intellect, greatly influenced by women. I will go even farther; and I will venture to say that those who have not undergone that influence betray a something incomplete and mutilated. We detect, even in their genius, a certain frigidity of tone; and we look in vain for that burning fire, that gushing and spontaneous nature with which our ideas of genius are indissolubly associated. Therefore, it is, that those who are most anxious that the boundaries of knowledge should be enlarged, ought to be most eager that the influence of women should be increased, in order that every resource of the human mind may be at once and quickly brought into play.

Anybody who looks at living organisms knows perfectly well that they can produce other organisms like themselves. This is their normal function, they wouldn’t exist if they didn’t do this, and it’s not plausible that this is the reason why they abound in the world. In other words, living organisms are very complicated aggregations of elementary parts, and by any reasonable theory of probability or thermodynamics highly improbable. That they should occur in the world at all is a miracle of the first magnitude; the only thing which removes, or mitigates, this miracle is that they reproduce themselves. Therefore, if by any peculiar accident there should ever be one of them, from there on the rules of probability do not apply, and there will be many of them, at least if the milieu is reasonable. But a reasonable milieu is already a thermodynamically much less improbable thing. So, the operations of probability somehow leave a loophole at this point, and it is by the process of self-reproduction that they are pierced.

Arithmetic is where the answer is right and everything is nice and you can look out of the window and see the blue sky—or the answer is wrong and you have to start all over and try again and see how it comes out this time.

Around here, however, we don't look backwards for very long. We keep moving forward, opening up new doors, and doing new things, because we're curious and curiosity keeps leading us down new paths.

Art gallery? Who needs it? Look up at the swirling silver-lined clouds in the magnificent blue sky or at the silently blazing stars at midnight. How could indoor art be any more masterfully created than God’s museum of nature?

As a scientist and geneticist I started to feel that science would probably soon reach the point where its interference into the life processes would be counterproductive if a properly designed governing policy was not implemented. A heavily overcrowded planet, ninety-five percent urbanized with nuclear energy as the main source of energy and with all aspects of life highly computerized, is not too pleasant a place for human life. The life of any individual soon will be predictable from birth to death. Medicine, able to cure almost everything, will make the load of accumulated defects too heavy in the next two or three centuries. The artificial prolongation of life, which looked like a very bright idea when I started research in aging about twenty-five years ago, has now lost its attractiveness for me. This is because I now know that the aging process is so multiform and complex that the real technology and chemistry of its prevention by artificial interference must be too complex and expensive. It would be the privilege of a few, not the method for the majority. I also was deeply concerned about the fact that most research is now either directly or indirectly related to military projects and objectives for power.

As I look back over my efforts, I would characterize my contributions as being largely in the realm of model building. ... I perceive myself as rather uninhibited, with a certain mathematical facility and more interest in the broad aspect of a problem than the delicate nuances. I am more interested in discovering what is over the next rise than in assiduously cultivating the beautiful garden close at hand.

As I looked down, I saw a large river meandering slowly along for miles, passing from one country to another without stopping. I also saw huge forests, extending along several borders. And I watched the extent of one ocean touch the shores of separate continents. Two words leaped to mind as I looked down on all this: commonality and interdependence. We are one world.

As much as we’ve enjoyed it up here, we’re also starting to look forward to seeing all the people back on Earth that we miss and love so much.

As soon … as it was observed that the stars retained their relative places, that the times of their rising and setting varied with the seasons, that sun, moon, and planets moved among them in a plane, … then a new order of things began.… Science had begun, and the first triumph of it was the power of foretelling the future; eclipses were perceived to recur in cycles of nineteen years, and philosophers were able to say when an eclipse was to be looked for. The periods of the planets were determined. Theories were invented to account for their eccentricities; and, false as those theories might be, the position of the planets could be calculated with moderate certainty by them.

As the skies appear to a man, so is his mind. Some see only clouds there; some, prodigies and portents; some rarely look up at all; their heads, like the brutes, are directed toward Earth. Some behold there serenity, purity, beauty ineffable. The world runs to see the panorama, when there is a panorama in the sky which few go to see.

As we look out into the Universe and identify the many accidents of physics and astronomy that have worked together to our benefit, it almost seems as if the Universe must in some sense have known that we were coming.

As you sit on the hillside, or lie prone under the trees of the forest, or sprawl wet-legged on the shingly beach of a mountain stream, the great door, that does not look like a door, opens.

Astronomers have built telescopes which can show myriads of stars unseen before; but when a man looks through a tear in his own eye, that is a lens which opens reaches into the unknown, and reveals orbs which no telescope, however skilfully constructed, could do.

Astronomy, as the science of cyclical motions, has nothing in common with Geology. But look at Astronomy where she has an analogy with Geology; consider our knowledge of the heavens as a palaetiological science;—as the study of a past condition, from which the present is derived by causes acting in time. Is there no evidence of a beginning, or of a progress?

At a given instant everything the surgeon knows suddenly becomes important to the solution of the problem. You can't do it an hour later, or tomorrow. Nor can you go to the library and look it up.

At the age of three I began to look around my grandfather’s library. My first knowledge of astronomy came from reading and looking at pictures at that time. By the time I was six I remember him buying books for me. … I think I was eight, he bought me a three-inch telescope on a brass mounting. It stood on a table. … So, as far back as I can remember, I had an early interest in science in general, astronomy in particular.

Be glad of life, because it gives you the chance to love and to work and to play and to look up at the stars.

Before counting the stars have a look underfoot.

But for us, it’s different. Look again at that dot. That’s here. That’s home. That’s us. On it everyone you love, everyone you know, everyone you ever heard of, every human being who ever was, lived out their lives. The aggregate of our joy and suffering, thousands of confident religions, ideologies, and economic doctrines, every hunter and forager, every hero and coward, every creator and destroyer of civilization, every king and peasant, every young couple in love, every mother and father, hopeful child, inventor and explorer, every teacher of morals, every corrupt politician, every “superstar,” every “supreme leader,” every saint and sinner in the history of our species lived there - on a mote of dust suspended in a sunbeam.

But here it may be objected, that the present Earth looks like a heap of Rubbish and Ruines; And that there are no greater examples of confusion in Nature than Mountains singly or jointly considered; and that there appear not the least footsteps of any Art or Counsel either in the Figure and Shape, or Order and Disposition of Mountains and Rocks. Wherefore it is not likely they came so out of God's hands ... To which I answer, That the present face of the Earth with all its Mountains and Hills, its Promontaries and Rocks, as rude and deformed as they appear, seems to me a very beautiful and pleasant object, and with all the variety of Hills, and Valleys, and Inequalities far more grateful to behold, than a perfectly level Countrey without any rising or protuberancy, to terminate the sight: As anyone that hath but seen the Isle of Ely, or any the like Countrey must need acknowledge.

Can any thoughtful person admit for a moment that, in a society so constituted that these overwhelming contrasts of luxury and privation are looked upon as necessities, and are treated by the Legislature as matters with which it has practically nothing do, there is the smallest probability that we can deal successfully with such tremendous social problems as those which involve the marriage tie and the family relation as a means of promoting the physical and moral advancement of the race? What a mockery to still further whiten the sepulchre of society, in which is hidden ‘all manner of corruption,’ with schemes for the moral and physical advancement of the race!

Change is the law of life. And those who look only to the past or the present are certain to miss the future.

Chuang Tzu and Hui Tzu were standing on the bridge across the Hao River. Chuang Tzu said, “Look how the minnows are shooting to and fro! How joyful they are!”
“You are not a fish,” said Hui Tzu. “How can you know that the fishes are joyful?”
“You are not I,” answered Chuang Tzu, “How can you know I do not know about the joy of fishes? ... I know it from my own joy of the water.”
An ancient Chinese story

Classification is now a pejorative statement. You know, these classifiers look like “dumb fools.” I’m a classifier. But I’d like to use a word that includes more than what people consider is encompassed by classification. It is more than that, and it’s something which can be called phenomenology.

Colour, Figure, Motion, Extension and the like, considered only so many Sensations in the Mind, are perfectly known, there being nothing in them which is not perceived. But if they are looked on as notes or Images, referred to Things or Archetypes existing without the Mind, then are we involved all in Scepticism.

Conflicts between men are almost always a matter of frontiers. The astronauts now have destroyed what looked like an unsurmountable frontier. They have shown us that we cannot any longer think in limited terms. There are no limitations left. We can think in terms of the universe now.

Connected by innumerable ties with abstract science, Physiology is yet in the most intimate relation with humanity; and by teaching us that law and order, and a definite scheme of development, regulate even the strangest and wildest manifestations of individual life, she prepares the student to look for a goal even amidst the erratic wanderings of mankind, and to believe that history offers something more than an entertaining chaos—a journal of a toilsome, tragi-comic march nowither.

Consider now the Milky Way. Here also we see an innumerable dust, only the grains of this dust are no longer atoms but stars; these grains also move with great velocities, they act at a distance one upon another, but this action is so slight at great distances that their trajectories are rectilineal; nevertheless, from time to time, two of them may come near enough together to be deviated from their course, like a comet that passed too close to Jupiter. In a word, in the eyes of a giant, to whom our Suns were what our atoms are to us, the Milky Way would only look like a bubble of gas.

Considering that, among all those who up to this time made discoveries in the sciences, it was the mathematicians alone who had been able to arrive at demonstrations—that is to say, at proofs certain and evident—I did not doubt that I should begin with the same truths that they have investigated, although I had looked for no other advantage from them than to accustom my mind to nourish itself upon truths and not to be satisfied with false reasons.

Creative imagination is likely to find corroborating novel evidence even for the most 'absurd' programme, if the search has sufficient drive. This look-out for new confirming evidence is perfectly permissible. Scientists dream up phantasies and then pursue a highly selective hunt for new facts which fit these phantasies. This process may be described as “science creating its own universe” (as long as one remembers that “creating” here is used in a provocative-idiosyncratic sense). A brilliant school of scholars (backed by a rich society to finance a few well-planned tests) might succeed in pushing any fantastic programme ahead, or alternatively, if so inclined, in overthrowing any arbitrarily chosen pillar of “established knowledge”.

Creativity makes a leap, then looks to see where it is.

Cuvier … brings the void to life again, without uttering abracadabras, he excavates a fragment of gypsum, spies a footprint and shouts: “Look!” And suddenly the marbles are teeming with creatures, the dead come to life again, the world turns!

Darwin's characteristic perspicacity is nowhere better illustrated than in his prophecy of the reaction of the world of science. He admitted at once that it would be impossible to convince those older men '...whose minds are stocked with a multitude of facts, all viewed ... from a point of view directly opposite to mine ... A few naturalists endowed with much flexibility of mind and who have already begun to doubt the immutability of species, may be influenced by this volume; but I look with confidence to the young and rising naturalists, who will be able to view both sides with equal impartiality.

Death, like the sun, cannot be looked at steadily.

Developmental Biology, in capitals, is the wave of the future. The creeping reductionism of biochemistry and molecular biology has taken over the cell and heredity, and looks covetously toward the heights of development and evolution. Recent literature is last year. Ancient literature is a decade ago. The rest is history, doubtfully alive. There is no time and often no opportunity to find and study the work of experimental biologists of 50 or 100 years ago, yet that was a time when the world was fresh.
Developmental biology was a lowercase phrase that graduated about 1950 and had previously lived under the cloak of Experimental Zoology

Dibdin said: “I see you've put your own name at the top of your paper, Mr Woods.” His eyes looked sad and thoughtful. “I always make it a matter of principle to put my name as well on every paper that comes out of the department.” “Yours?” Albert said incredulously. “Yes,”said Dibdin, still sad and thoughtful. “I make it a matter of principle, Mr Woods. And I like my name to come first—it makes it easier for purposes of identification.” He rounded it off. “First come, first served.”

Dr. Walter Baade of Mount Wilson Observatory facetiously accused the present generation of Milky Way astronomers of not having looked sufficiently far beyond our “local swimming hole”.

During the school period the student has been mentally bending over his desk; at the University he should stand up and look around. For this reason it is fatal if the first year at the University be frittered away in going over the old work in the old spirit. At school the boy painfully rises from the particular towards glimpses at general ideas; at the University he should start from general ideas and study their applications to concrete cases.

Each of us has read somewhere that in New Guinea pidgin the word for 'piano' is (I use English spelling) 'this fellow you hit teeth belonging to him he squeal all same pig'. I am inclined to doubt whether this expression is authentic; it looks just like the kind of thing a visitor to the Islands would facetiously invent. But I accept 'cut grass belong head belong me' for 'haircut' as genuine... Such phrases seem very funny to us, and make us feel very superior to the ignorant foreigners who use long winded expressions for simple matters. And then it is our turn to name quite a simple thing, a small uncomplicated molecule consisting of nothing more than a measly 11 carbons, seven hydrogens, one nitrogen and six oxygens. We sharpen our pencils, consult our rule books and at last come up with 3-[(1, 3- dihydro-1, 3-dioxo-2H-isoindol-2-yl) oxy]-3-oxopropanoic acid. A name like that could drive any self-respecting Papuan to piano-playing.

Einstein, twenty-six years old, only three years away from crude privation, still a patent examiner, published in the Annalen der Physik in 1905 five papers on entirely different subjects. Three of them were among the greatest in the history of physics. One, very simple, gave the quantum explanation of the photoelectric effect—it was this work for which, sixteen years later, he was awarded the Nobel prize. Another dealt with the phenomenon of Brownian motion, the apparently erratic movement of tiny particles suspended in a liquid: Einstein showed that these movements satisfied a clear statistical law. This was like a conjuring trick, easy when explained: before it, decent scientists could still doubt the concrete existence of atoms and molecules: this paper was as near to a direct proof of their concreteness as a theoretician could give. The third paper was the special theory of relativity, which quietly amalgamated space, time, and matter into one fundamental unity.
This last paper contains no references and quotes no authority. All of them are written in a style unlike any other theoretical physicist’s. They contain very little mathematics. There is a good deal of verbal commentary. The conclusions, the bizarre conclusions, emerge as though with the greatest of ease: the reasoning is unbreakable. It looks as though he had reached the conclusions by pure thought, unaided, without listening to the opinions of others. To a surprisingly large extent, that is precisely what he had done.

Environmental extremists ... wouldn’t let you build a house unless it looked like a bird’s nest.

Ethnologists regard man as the primitive element of tribes, races, and peoples. The anthropologist looks at him as a member of the fauna of the globe, belonging to a zoölogical classification, and subject to the same laws as the rest of the animal kingdom. To study him from the last point of view only would be to lose sight of some of his most interesting and practical relations; but to be confined to the ethnologist’s views is to set aside the scientific rule which requires us to proceed from the simple to the compound, from the known to the unknown, from the material and organic fact to the functional phenomenon.

Euclid alone has looked on Beauty bare.
Let all who prate of Beauty hold their peace,
And lay them prone upon the earth and cease
To ponder on themselves, the while they stare
At nothing, intricately drawn nowhere
In shapes of shifting lineage; let geese
Gabble and hiss, but heroes seek release
From dusty bondage into luminous air.
O blinding hour, O holy, terrible day,
When first the shaft into his vision shone
Of light anatomized! Euclid alone
Has looked on Beauty bare. Fortunate they
Who, though once only and then but far away,
Have heard her massive sandal set on stone.

Euclid alone
Has looked on Beauty bare.
He turned away at once;
Far too polite to stare.

Even fairly good students, when they have obtained the solution of the problem and written down neatly the argument, shut their books and look for something else. Doing so, they miss an important and instructive phase of the work. ... A good teacher should understand and impress on his students the view that no problem whatever is completely exhausted.

Even the mind depends so much on temperament and the disposition of one’s bodily organs that, if it is possible to find a way to make people generally more wise and more skilful than they have been in the past, I believe that we should look for it in medicine. It is true that medicine as it is currently practiced contains little of much use.

Every generation has the obligation to free men’s minds for a look at new worlds… to look out from a higher plateau than the last generation.

Every investigator must before all things look upon himself as one who is summoned to serve on a jury. He has only to consider how far the statement of the case is complete and clearly set forth by the evidence. Then he draws his conclusion and gives his vote, whether it be that his opinion coincides with that of the foreman or not.

Every man looks at his wood-pile with a kind of affection. … [T]hey warmed me twice, once while I was splitting them, and again when they were on the fire, so that no fuel could give out more heat.

Everywhere you look in science, the harder it becomes to understand the universe without God.

Evolution: At the Mind's Cinema
I turn the handle and the story starts:
Reel after reel is all astronomy,
Till life, enkindled in a niche of sky,
Leaps on the stage to play a million parts.
Life leaves the slime and through all ocean darts;
She conquers earth, and raises wings to fly;
Then spirit blooms, and learns how not to die,-
Nesting beyond the grave in others' hearts.
I turn the handle: other men like me
Have made the film: and now I sit and look
In quiet, privileged like Divinity
To read the roaring world as in a book.
If this thy past, where shall they future climb,
O Spirit, built of Elements and Time?