Significance Quotes (60 quotes)
The classification of facts, the recognition of their sequence and relative significance is the function of science, and the habit of forming a judgment upon these facts unbiassed by personal feeling is characteristic of what may be termed the scientific frame of mind.
The Word Reason in the English Language has different Significances: sometimes it is taken for true, and clear Principles: Sometimes for clear, and fair deductions from those Principles: and sometimes for Cause, and particularly the final Cause: but the Consideration I shall have of it here, is in a Signification different from all these; and that is, as it stands for a Faculty of Man, That Faculty, whereby Man is supposed to be distinguished from Beasts; and wherein it is evident he much surpasses them.
A living organism must be studied from two distinct aspects. One of these is the causal-analytic aspect which is so fruitfully applicable to ontogeny. The other is the historical descriptive aspect which is unravelling lines of phylogeny with ever-increasing precision. Each of these aspects may make suggestions concerning the possible significance of events seen under the other, but does not explain or translate them into simpler terms.
A multidisciplinary study group ... estimated that it would be 1980 before developments in artificial intelligence make it possible for machines alone to do much thinking or problem solving of military significance. That would leave, say, five years to develop man-computer symbiosis and 15 years to use it. The 15 may be 10 or 500, but those years should be intellectually the most creative and exciting in the history of mankind.
A person who is religiously enlightened appears to me to be one who has, to the best of his ability, liberated himself from the fetters of his selfish desires and is preoccupied with thoughts, feelings, and aspirations to which he clings because of their superpersonal value. It seems to me that what is important is the force of this superpersonal content and the depth of the conviction concerning its overpowering meaningfulness, regardless of whether any attempt is made to unite this content with a divine Being, for otherwise it would not be possible to count Buddha and Spinoza as religious personalities. Accordingly, a religious person is devout in the sense that he has no doubt of the significance and loftiness of those superpersonal objects and goals which neither require nor are capable of rational foundation. They exist with the same necessity and matter-of-factness as he himself. In this sense religion is the age-old endeavor of mankind to become clearly and completely conscious of these values and goals and constantly to strengthen and extend their effect. If one conceives of religion and science according to these definitions then a conflict between them appears impossible. For science can only ascertain what is, but not what should be, and outside of its domain value judgments of all kinds remain necessary.
Across the road from my cabin was a huge clear-cut—hundreds of acres of massive spruce stumps interspersed with tiny Douglas firs—products of what they call “Reforestation,” which I guess makes the spindly firs en masse a “Reforest,” which makes an individual spindly fir a “Refir,” which means you could say that Weyerhauser, who owns the joint, has Refir Madness, since they think that sawing down 200-foot-tall spruces and replacing them with puling 2-foot Refirs is no different from farming beans or corn or alfalfa. They even call the towering spires they wipe from the Earth's face forever a “crop”--as if they'd planted the virgin forest! But I'm just a fisherman and may be missing some deeper significance in their nomenclature and stranger treatment of primordial trees.
All revolutionary advances in science may consist less of sudden and dramatic revelations than a series of transformations, of which the revolutionary significance may not be seen (except afterwards, by historians) until the last great step. In many cases the full potentiality and force of a most radical step in such a sequence of transformations may not even be manifest to its author.
As for the excellent little wretches who grow up in what they are taught, with never a scruple or a query, ... they signify nothing in the intellectual life of the race.
But among all these many departments of research, these many branches of industry, new and old, which are being rapidly expanded, there is one dominating all others in importance—one which is of the greatest significance for the comfort and welfare, not t
Clarity about the aims and problems of socialism is of greatest significance in our age of transition. Since, under present circumstances, free and unhindered discussion of these problems has come under a powerful taboo, I consider the foundation of this magazine to be an important public service.
Every dream will reveal itself as a psychological structure, full of significance
Formal symbolic representation of qualitative entities is doomed to its rightful place of minor significance in a world where flowers and beautiful women abound.
Haemoglobin is a very large molecule by ordinary standards, containing about ten thousand atoms, but the chances are that your haemoglobin and mine are identical, and significantly different from that of a pig or horse. You may be impressed by how much human beings differ from one another, but if you were to look into the fine details of the molecules of which they are constructed, you would be astonished by their similarity.
Hardly a year passes that fails to find a new, oft-times exotic, research method or technique added to the armamentarium of political inquiry. Anyone who cannot negotiate Chi squares, assess randomization, statistical significance, and standard deviations
Hitherto the principle of causality was universally accepted as an indispensable postulate of scientific research, but now we are told by some physicists that it must be thrown overboard. The fact that such an extraordinary opinion should be expressed in responsible scientific quarters is widely taken to be significant of the all-round unreliability of human knowledge. This indeed is a very serious situation.
Human judgment is notoriously fallible and perhaps seldom more so than in facile decisions that a character has no adaptive significance because we do not know the use of it.
Hypothesis is the most important mental technique of the investigator, and its main function is to suggest new experiments or new observations. Indeed, most experiments and many observations are carried out with the deliberate object of testing an hypothesis. Another function is to help one see the significance of an object or event that otherwise would mean nothing. For instance, a mind prepared by the hypothesis of evolution would make many more significant observations on a field excursion than one not so prepared. Hypotheses should be used as tools to uncover new facts rather than as ends in themselves.
I do not see any reason to assume that the heuristic significance of the principle of general relativity is restricted to gravitation and that the rest of physics can be dealt with separately on the basis of special relativity, with the hope that later on the whole may be fitted consistently into a general relativistic scheme. I do not think that such an attitude, although historically understandable, can be objectively justified. The comparative smallness of what we know today as gravitational effects is not a conclusive reason for ignoring the principle of general relativity in theoretical investigations of a fundamental character. In other words, I do not believe that it is justifiable to ask: What would physics look like without gravitation?
I have presented the periodic table as a kind of travel guide to an imaginary country, of which the elements are the various regions. This kingdom has a geography: the elements lie in particular juxtaposition to one another, and they are used to produce goods, much as a prairie produces wheat and a lake produces fish. It also has a history. Indeed, it has three kinds of history: the elements were discovered much as the lands of the world were discovered; the kingdom was mapped, just as the world was mapped, and the relative positions of the elements came to take on a great significance; and the elements have their own cosmic history, which can be traced back to the stars.
If you ask ... the man in the street ... the human significance of mathematics, the answer of the world will be, that mathematics has given mankind a metrical and computatory art essential to the effective conduct of daily life, that mathematics admits of countless applications in engineering and the natural sciences, and finally that mathematics is a most excellent instrumentality for giving mental discipline... [A mathematician will add] that mathematics is the exact science, the science of exact thought or of rigorous thinking.
If, as I have reason to believe, I have disintegrated the nucleus of the atom, this is of greater significance than the war.
[Apology to the international anti-submarine committee for being absent from several meetings during World War I.]
[Apology to the international anti-submarine committee for being absent from several meetings during World War I.]
In our day grand generalizations have been reached. The theory of the origin of species is but one of them. Another, of still wider grasp and more radical significance, is the doctrine of the Conservation of Energy, the ultimate philosophical issues of which are as yet but dimly seem-that doctrine which “binds nature fast in fate” to an extent not hitherto recognized, exacting from every antecedent its equivalent consequent, and bringing vital as well as physical phenomena under the dominion of that law of causal connexion which, so far as the human understanding has yet pierced, asserts itself everywhere in nature.
It has been recognized that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as the methods of structural chemistry are further applied to physiological problems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature.
Its immediate significance was as a currency, for it closed the triangle linking spirits, slaves, and sugar. Rum could be used to buy slaves, with which to produce sugar, the leftovers of which could be made into rum to buy more slaves, and so on and on.
It’s hard to explain to people what the significance of an invention is, so it’s hard to get funding. The first thing they say is that it can’t be done. Then they say, “You didn't do it right.” Then, when you’ve done it, they finally say, “Well, it was obvious anyway.”
Laughter that occurs during tickling of the axillary region and the soles of the feet, as well as the laughter that occurs when seeing comical things or when hearing comical things, has no practical diagnostic significance.
Laws, in their most general signification, are the necessary relations arising from the nature of things. In this sense all beings have their laws: the Deity His laws, the material world its laws, the intelligences superior to man their laws, the beasts their laws, man his laws.
Mathematics, as much as music or any other art, is one of the means by which we rise to a complete self-consciousness. The significance of mathematics resides precisely in the fact that it is an art; by informing us of the nature of our own minds it informs us of much that depends on our minds.
Modern cytological work involves an intricacy of detail, the significance of which can be appreciated by the specialist alone; but Miss Stevens had a share in a discovery of importance, and her work will be remembered for this, when the minutiae of detailed investigations that she carried out have become incorporated in the general body of the subject.
My eureka moment was in the dead of night, the early hours of the morning, on a cold, cold night, and my feet were so cold, they were aching. But when the result poured out of the charts, you just forget all that. You realize instantly how significant this is—what it is you’ve really landed on—and it’s great!
[About her discovery of the first pulsar radio signals.]
[About her discovery of the first pulsar radio signals.]
Nature is a vast tablet, inscribed with signs, each of which has its own significancy, and becomes poetry in the mind when read; and geology is simply the key by which myriads of these signs, hitherto indecipherable, can be unlocked and perused, and thus a new province added to the poetical domain.
No one must think that Newton’s great creation can be overthrown in any real sense by this [Theory of Relativity] or by any other theory. His clear and wide ideas will for ever retain their significance as the foundation on which our modern conceptions of physics have been built.
Of what significance is one’s one existence, one is basically unaware. What does a fish know about the water in which he swims all his life? The bitter and the sweet come from outside. The hard from within, from one’s own efforts. For the most part I do what my own nature drives me to do. It is embarrassing to earn such respect and love for it.
Science is a speculative enterprise. The validity of a new idea and the significance of a new experimental finding are to be measured by the consequences—consequences in terms of other ideas and other experiments. Thus conceived, science is not a quest for certainty; it is rather a quest which is successful only to the degree that it is continuous.
Scientific inquiry would thus he conceived of as analogous to terrestrial exploration, whose product—geography—yields results of continually smaller significance which fill in ever more minute gaps in our information. In such a view, later investigations yield findings of ever smaller importance, with each successive accretion making a relatively smaller contribution to what has already come to hand. The advance of science leads, step by diminished step, toward a fixed and final view of things.
The chemical differences among various species and genera of animals and plants are certainly as significant for the history of their origins as the differences in form. If we could define clearly the differences in molecular constitution and functions of different kinds of organisms, there would be possible a more illuminating and deeper understanding of question of the evolutionary reactions of organisms than could ever be expected from morphological considerations.
The Commissioner of Patents may be likened to a wine merchant. He has in his office the wine of human progress of every kind and quality—wine, one may say, produced from the fermentation of the facts of the world through the yeast of human effort. Sometimes the yeast is “wild” and sometimes the “must” is poor, and while it all lies there shining with its due measure of the sparkle of divine effort, it is but occasionally that one finds a wine whose bouquet is the result of a pure culture on the true fruit of knowledge. But it is this true, pure wine of discovery that is alone of lasting significance.
The energy of a covalent bond is largely the energy of resonance of two electrons between two atoms. The examination of the form of the resonance integral shows that the resonance energy increases in magnitude with increase in the overlapping of the two atomic orbitals involved in the formation of the bond, the word ‘overlapping” signifying the extent to which regions in space in which the two orbital wave functions have large values coincide... Consequently it is expected that of two orbitals in an atom the one which can overlap more with an orbital of another atom will form the stronger bond with that atom, and, moreover, the bond formed by a given orbital will tend to lie in that direction in which the orbital is concentrated.
The engineer is concerned to travel from the abstract to the concrete. He begins with an idea and ends with an object. He journeys from theory to practice. The scientist’s job is the precise opposite. He explores nature with his telescopes or microscopes, or much more sophisticated techniques, and feeds into a computer what he finds or sees in an attempt to define mathematically its significance and relationships. He travels from the real to the symbolic, from the concrete to the abstract. The scientist and the engineer are the mirror image of each other.
The evidence from both approaches, statistical and experimental, does not appear sufficiently significant to me to warrant forsaking the pleasure of smoking. As a matter of fact, if the investigations had been pointed toward some material that I thoroughly dislike, such as parsnips, I still would not feel that evidence of the type presented constituted a reasonable excuse for eliminating the things from my diet. I will still continue to smoke, and if the tobacco companies cease manufacturing their product, I will revert to sweet fern and grape leaves.
The extensive literature addressed to the definition or characterization of science is filled with inconsistent points of view and demonstrates that an adequate definition is not easy to attain. Part of the difficulty arises from the fact that the meaning of science is not fixed, but is dynamic. As science has evolved, so has its meaning. It takes on a new meaning and significance with successive ages.
The faith of scientists in the power and truth of mathematics is so implicit that their work has gradually become less and less observation, and more and more calculation. The promiscuous collection and tabulation of data have given way to a process of assigning possible meanings, merely supposed real entities, to mathematical terms, working out the logical results, and then staging certain crucial experiments to check the hypothesis against the actual empirical results. But the facts which are accepted by virtue of these tests are not actually observed at all. With the advance of mathematical technique in physics, the tangible results of experiment have become less and less spectacular; on the other hand, their significance has grown in inverse proportion. The men in the laboratory have departed so far from the old forms of experimentation—typified by Galileo's weights and Franklin's kite—that they cannot be said to observe the actual objects of their curiosity at all; instead, they are watching index needles, revolving drums, and sensitive plates. No psychology of 'association' of sense-experiences can relate these data to the objects they signify, for in most cases the objects have never been experienced. Observation has become almost entirely indirect; and readings take the place of genuine witness.
The following lesson is of great and important significance, worthy of committing to memory, namely, in arranging the composition of medications one should pay careful attention and direct one’s willpower, because many times antagonistic medicines become mixed in which are useless and inappropriate for their intended use.
The individual, if left alone from birth would remain primitive and beast-like in his thoughts and feelings to a degree that we can hardly conceive. The individual is what he is and has the significance that he has not so much in virtue of his individuality, but rather as a member of a great human society, which directs his material and spiritual existence from the cradle to the grave.
The laws of Coexistence;—the adaptation of structure to function; and to a certain extent the elucidation of natural affinities may be legitimately founded upon the examination of fully developed species;—But to obtain an insight into the laws of development,—the signification or bedeutung, of the parts of an animal body demands a patient examination of the successive stages of their development, in every group of Animals.
The main purpose of a significance test is to inhibit the natural enthusiasm of the investigator.
The major gift of science to the world is a mighty increase of power. Did science then create that power? Not a bit of it! Science discovered that power in the universe and set it free. Science found out the conditions, fulfilling which, the endless dynamic forces of the cosmos are liberated. Electricity is none of man’s making, but man has learned how to fulfill the conditions that release it. Atomic energy is a force that man did not create, but that some day man may liberate. Man by himself is still a puny animal; a gorilla is much the stronger. Man's significance lies in another realm—he knows how to fulfill conditions so that universal power not his own is set free. The whole universe as man now sees it is essentially a vast system of power waiting to be released.
The more you understand the significance of evolution, the more you are pushed away from the agnostic position and towards atheism. Complex, statistically improbable things are by their nature more difficult to explain than simple, statistically probable things.
The role of biology today, like the role of every other science, is simply to describe, and when it explains it does not mean that it arrives at finality; it only means that some descriptions are so charged with significance that they expose the relationship of cause and effect.
The significance of a fact is relative to [the general body of scientific] knowledge. To say that a fact is significant in science, is to say that it helps to establish or refute some general law; for science, though it starts from observation of the particular, is not concerned essentially with the particular, but with the general. A fact, in science, is not a mere fact, but an instance. In this the scientist differs from the artist, who, if he deigns to notice facts at all, is likely to notice them in all their particularity.
The significance of man is that he is insignificant and is aware of it.
The Theory of Relativity confers an absolute meaning on a magnitude which in classical theory has only a relative significance: the velocity of light. The velocity of light is to the Theory of Relativity as the elementary quantum of action is to the Quantum Theory: it is its absolute core.
These days at ten o’clock at night a most alarming wonder has manifested itself in the skies. The firmament was rent asunder and through this gap one could distinguish chariots and armies, riders with yellow, white, red and black standards, though to do battle against each other. This awesome and unusual vision continued from ten at night till about two of the morning, and was witnessed with alarm and dismay by many honest and trustworthy people. The significance thereof is known but to God Almighty, Who may graciously prevent the shedding of innocent blood.
This interpretation of the atomic number [as the number of orbital electrons] may be said to signify an important step toward the solution of the boldest dreams of natural science, namely to build up an understanding of the regularities of nature upon the consideration of pure number.
To be anthropocentric is to remain unaware of the limits of human nature, the significance of biological processes underlying human behavior, and the deeper meaning of long-term genetic evolution.
When we survey our lives and endeavours we soon observe that almost the whole of our actions and desires are bound up with the existence of other human beings. We see that our whole nature resembles that of the social animals. We eat food that others have grown, wear clothes that others have made, live in houses that others have built. The greater part of our knowledge and beliefs has been communicated to us by other people through the medium of a language which others have created. Without language our mental capacities would be poor indeed, comparable to those of the higher animals; we have, therefore, to admit that we owe our principal advantage over the beasts to the fact of living in human society. The individual, if left alone from birth would remain primitive and beast-like in his thoughts and feelings to a degree that we can hardly conceive. The individual is what he is and has the significance that he has not so much in virtue of his individuality, but rather as a member of a great human society, which directs his material and spiritual existence from the cradle to the grave.
You can be a thorough-going Neo-Darwinian without imagination, metaphysics, poetry, conscience, or decency. For “Natural Selection” has no moral significance: it deals with that part of evolution which has no purpose, no intelligence, and might more appropriately be called accidental selection, or better still, Unnatural Selection, since nothing is more unnatural than an accident. If it could be proved that the whole universe had been produced by such Selection, only fools and rascals could bear to live.
[A significant invention] must be startling, unexpected. It must come to a world that is not prepared for it.
[Decoding the human genome sequence] is the most significant undertaking that we have mounted so far in an organized way in all of science. I believe that reading our blueprints, cataloguing our own instruction book, will be judged by history as more significant than even splitting the atom or going to the moon.
[T]he rapt philosopher, and he who contemplates a work of art, inhabit a world with an intense and peculiar significance of its own; that significance is unrelated to the significance of life.