…it ought to be remembered that there is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things. Because the innovator has for enemies all those who have done well under the old conditions, and lukewarm defenders in those who may do well under the new.

...while science gives us implements to use, science alone does not determine for what ends they will be employed. Radio is an amazing invention. Yet now that it is here, one suspects that Hitler never could have consolidated his totalitarian control over Germany without its use. One never can tell what hands will reach out to lay hold on scientific gifts, or to what employment they will be put. Ever the old barbarian emerges, destructively using the new civilization.

“Planning” is simply the result of experience read backward and projected into the future. To me the “purposive” action of a beehive is simply the summation and integration of its units, and Natural Selection has put higher and higher premiums on the most “purposeful” integration. It is the same way (to me) in the evolution of the middle ear, the steps in the Cynodonts (clearly shown by me in 1910 and by you later in Oudenodon) make it easier to see how such a wonderful device as the middle ear could arise without any predetermination or human-like planning, and in fact in the good old Darwinian way, if only we admit that as the “twig is bent the tree’s inclined” and that each stage conserves the advantages of its predecessors… The simple idea that planning is only experience read backward and combined by selection in suitable or successful combinations takes the mystery out of Nature and out of men’s minds.

“The Ancient Mariner” — This poem would not have taken so well if it had been called “The Old Sailor,” so that Wardour Street has its uses.

[About the structure of DNA] [T]he whole business was like a child's toy that you could buy at the dime store, all built in this wonderful way that you could explain in Life magazine so that really a five-year-old can understand what's going on...This was the greatest surprise for everyone.

[Alchemists] finde out men so covetous of so much happiness, whom they easily perswade that they shall finde greater Riches in Hydargyrie [mercury], than Nature affords in Gold. Such, whom although they have twice or thrice already been deluded, yet they have still a new Device wherewith to deceive um again; there being no greater Madness…. So that the smells of Coles, Sulphur, Dung, Poyson, and Piss, are to them a greater pleasure than the taste of Honey; till their Farms, Goods, and Patrimonies being wasted, and converted into Ashes and Smoak, when they expect the rewards of their Labours, births of Gold, Youth, and Immortality, after all their Time and Expences; at length, old, ragged, famisht, with the continual use of Quicksilver [mercury] paralytick, onely rich in misery, … a laughing-stock to the people: … compell’d to live in the lowest degree of poverty, and … at length compell’d thereto by Penury, they fall to Ill Courses, as Counterfeiting of Money.

[An] old Pythagorean prejudice … thought it a crime to eat eggs; because an egg was a microcosm, or universe in little; the shell being the earth; the white, water; fire, the yolk; and the air found between the shell and the white.

[Edison] definitely ended the distinction between the theoretical man of science and the practical man of science, so that today we think of scientific discoveries in connection with their possible present or future application to the needs of man. He took the old rule-of-thumb methods out of industry and substituted exact scientific knowledge, while, on the other hand, he directed scientific research into useful channels.

[In childhood, to overcome fear, the] need took me back again and again to a sycamore tree rising from the earth at the edge of a ravine. It was a big, old tree that had grown out over the ravine, so that when you climbed it, you looked straight down fifty feet or more. Every time I climbed that tree, I forced myself to climb to the last possible safe limb and then look down. Every time I did it, I told myself I’d never do it again. But I kept going back because it scared me and I had to know I could overcome that.

[Niels Bohr] is a national pride to his fellow Danes. In Denmark, Bohr’s standing is only slightly less than that of the royal family and Hans Christian Anderson. When the wife of an American physicist casually told a gentleman seated next to her on a Copenhagen streetcar that her husband was studying under Professor Bohr, the old man jumped to his feet, swept off his hat with a flourish and bowed deeply.

[On the future of Chemistry:] Chemistry is not the preservation hall of old jazz that it sometimes looks like. We cannot know what may happen tomorrow. Someone may oxidize mercury (II), francium (I), or radium (II). A mineral in Nova Scotia may contain an unsaturated quark per 1020 nucleons. (This is still 6000 per gram.) We may pick up an extraterrestrial edition of Chemical Abstracts. The universe may be a 4-dimensional soap bubble in an 11-dimensional space as some supersymmetry theorists argued in May of 1983. Who knows?

[Penguins] are extraordinarily like children, these little people of the Antarctic world, either like children, or like old men, full of their own importance and late for dinner, in their black tail-coats and white shirt-fronts — and rather portly withal.

[The attitude of the Renaissance towards the antique world was that] Archaeology to them was not a mere science for the antiquarian; it was a means by which they could touch the dry dust of antiquity into the very breath and beauty of life, and fill with the new wine of romanticism forms that else had been old and out-worn.

[The center must be more than just] old junk in a box. [It must be a] living dynamic thing to attract people to public service at all levels.

[The compass needle] as the guide of Vasco de Gama to the East Indies, and of Columbus to the West Indies and the New World, it was pre-eminently the precursor and pioneer of the telegraph. Silently, and as with finger on its lips, it led them across the waste of waters to the new homes of the world; but when these were largely filled, and houses divided between the old and new hemispheres longed to exchange affectionate greetings, it removed its finger and broke silence. The quivering magnetic needle which lies in the coil of the galvanometer is the tongue of the electric telegraph, and already engineers talk of it as speaking.

[There] are still to be found text-books of the old sort, teaching Mathematics under the guise of Physics, presenting nothing but the dry husks of the latter.

[W]e might expect intelligent life and technological communities to have emerged in the universe billions of years ago. Given that human society is only a few thousand years old, and that human technological society is mere centuries old, the nature of a community with millions or even billions of years of technological and social progress cannot even be imagined. ... What would we make of a billion-year-old technological community?

Πάντα ῥεῖ : all things are in flux. It is inevitable that you are indebted to the past. You are fed and formed by it. The old forest is decomposed for the composition of the new forest. The old animals have given their bodies to the earth to furnish through chemistry the forming race, and every individual is only a momentary fixation of what was yesterday another’s, is today his and will belong to a third to-morrow. So it is in thought.

[In refutation of evolution] They use carbon dating ... to prove that something was millions of years old. Well, we have the eruption of Mt. Saint Helens and the carbon dating test that they used then would have to then prove that these were hundreds of millions of years younger, when what happened was they had the exact same results on the fossils and canyons that they did the tests on that were supposedly 100 millions of years old. And it’s the kind of inconsistent tests like this that they’re basing their “facts” on.
[Citing results from a solitary young-Earth creationist, questioning whether the lava dome at Mount St. Helens is really a million years old.]

Lyveris to-forn us
Useden to marke
For selkouthes that thei seighen,
Hir sones for to teche;
And helden it an heigh science
Hir wittes to knowe.
Ac thorugh hir science soothly
Was nevere no soule y-saved,
Ne broght by hir bokes
To blisse ne to joye;
For alle hir kynde knowynges
Come but of diverse sightes.
Patriarkes and prophetes
Repreveden hir science,
And seiden hir wordes and hir wisdomes
Nas but a folye
And to the clergie of Crist
Counted it but a trufle.
Our ancestors in olden days used to record
The strange things they saw, and teach them to their sons;
And they held it a high science, to have knowledge of such things.
But no soul was ever saved by all that science,
Nor brought by books into eternal bliss;
Their science was only a series of sundry observations.
So patriarchs and prophets disapproved of their science,
And said their so-called words of wisdom were but folly—
And compared with Christian philosophy, a contemptible thing.

The Water-baby story character, Tom, asks: 'I heard, ma'am, that you were always making new beasts out of old.'
Mother Carey [Mother Nature] replies: 'So people fancy. But I am not going to trouble myself to make things, my little dear. I sit here and make them make themselves.'
[The author's indirect reference to evolution.]

~~[need primary source]~~ One of the most frightening things in the Western world and in this country in particular is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10000 years old in my opinion he should see a psychiatrist.

~~[Orphan]~~ All the significant breakthroughs were break-withs old ways of thinking.

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A complete theory of evolution must acknowledge a balance between ‘external’ forces of environment imposing selection for local adaptation and ‘internal’ forces representing constraints of inheritance and development. Vavilov placed too much emphasis on internal constraints and downgraded the power of selection. But Western Darwinians have erred equally in practically ignoring (while acknowledging in theory) the limits placed on selection by structure and development–what Vavilov and the older biologists would have called ‘laws of form.’

A drop of old tuberculin, which is an extract of tubercle bacilli, is put on the skin and then a small superficial scarification is made by turning, with some pressure, a vaccination lancet on the surface of the skin. The next day only those individuals show an inflammatory reaction at the point of vaccination who have already been infected with tuberculosis, whereas the healthy individuals show no reaction at all. Every time we find a positive reaction, we can say with certainty that the child is tuberculous.

A formative influence on my undergraduate self was the response of a respected elder statesmen of the Oxford Zoology Department when an American visitor had just publicly disproved his favourite theory. The old man strode to the front of the lecture hall, shook the American warmly by the hand and declared in ringing, emotional tones: “My dear fellow, I wish to thank you. I have been wrong these fifteen years.” And we clapped our hands red. Can you imagine a Government Minister being cheered in the House of Commons for a similar admission? “Resign, Resign” is a much more likely response!

A good method of discovery is to imagine certain members of a system removed and then see how what is left would behave: for example, where would we be if iron were absent from the world: this is an old example.

A grove of giant redwoods or sequoias should be kept just as we keep a great or beautiful cathedral. The extermination of the passenger pigeon meant that mankind was just so much poorer; exactly as in the case of the destruction of the cathedral at Rheims. And to lose the chance to see frigate-birds soaring in circles above the storm, or a file of pelicans winging their way homeward across the crimson afterglow of the sunset, or a myriad terns flashing in the bright light of midday as they hover in a shifting maze above the beach—why, the loss is like the loss of a gallery of the masterpieces of the artists of old time.

A hundred devils leap into my body, if there be not more old drunkards than old physicians.

A magician of old waved a wand that he might banish disease, a physician to-day peers through a microscope to detect the bacillus of that disease and plan its defeat. The belief in miracles was premature, that is all; it was based on dreams now coming true.

A man is as old as his arteries.

A man that is young in years may be old in hours, if he has lost no time.

A man who has once looked with the archaeological eye will never see quite normally. He will be wounded by what other men call trifles. It is possible to refine the sense of time until an old shoe in the bunch grass or a pile of nineteenth century beer bottles in an abandoned mining town tolls in one’s head like a hall clock.

A new truth is a truth, an old error is an error.

A parable: A man was examining the construction of a cathedral. He asked a stone mason what he was doing chipping the stones, and the mason replied, “I am making stones.” He asked a stone carver what he was doing. “I am carving a gargoyle.” And so it went, each person said in detail what they were doing. Finally he came to an old woman who was sweeping the ground. She said. “I am helping build a cathedral.”
...Most of the time each person is immersed in the details of one special part of the whole and does not think of how what they are doing relates to the larger picture.
[For example, in education, a teacher might say in the next class he was going to “explain Young's modulus and how to measure it,” rather than, “I am going to educate the students and prepare them for their future careers.”]

A persistent and age-old instinct makes us want to wander
Into regions yet untrod
And read what is still unread
In the manuscripts of God.

A person who is religiously enlightened appears to me to be one who has, to the best of his ability, liberated himself from the fetters of his selfish desires and is preoccupied with thoughts, feelings, and aspirations to which he clings because of their superpersonal value. It seems to me that what is important is the force of this superpersonal content and the depth of the conviction concerning its overpowering meaningfulness, regardless of whether any attempt is made to unite this content with a divine Being, for otherwise it would not be possible to count Buddha and Spinoza as religious personalities. Accordingly, a religious person is devout in the sense that he has no doubt of the significance and loftiness of those superpersonal objects and goals which neither require nor are capable of rational foundation. They exist with the same necessity and matter-of-factness as he himself. In this sense religion is the age-old endeavor of mankind to become clearly and completely conscious of these values and goals and constantly to strengthen and extend their effect. If one conceives of religion and science according to these definitions then a conflict between them appears impossible. For science can only ascertain what is, but not what should be, and outside of its domain value judgments of all kinds remain necessary.

A plain, reasonable working man supposes, in the old way which is also the common-sense way, that if there are people who spend their lives in study, whom he feeds and keeps while they think for him—then no doubt these men are engaged in studying things men need to know; and he expects of science that it will solve for him the questions on which his welfare, and that of all men, depends. He expects science to tell him how he ought to live: how to treat his family, his neighbours and the men of other tribes, how to restrain his passions, what to believe in and what not to believe in, and much else. And what does our science say to him on these matters?
It triumphantly tells him: how many million miles it is from the earth to the sun; at what rate light travels through space; how many million vibrations of ether per second are caused by light, and how many vibrations of air by sound; it tells of the chemical components of the Milky Way, of a new element—helium—of micro-organisms and their excrements, of the points on the hand at which electricity collects, of X rays, and similar things.
“But I don't want any of those things,” says a plain and reasonable man—“I want to know how to live.”

A propos of Distempers, I am going to tell you a thing that I am sure will make you wish your selfe here. The Small Pox so fatal and so general amongst us is here entirely harmless by the invention of engrafting (which is the term they give it). There is a set of old Women who make it their business to perform the Operation.

A religion old or new, that stressed the magnificence of the universe as revealed by modern science, might be able to draw forth reserves of reverence and awe hardly tapped by the conventional faiths. Sooner or later such a religion will emerge.

A road across the United States; Let’s build it before we’re too old to enjoy it. [About the Lincoln Highway]

A society grows great when old men plant trees whose shade they know they shall never sit in.

A specter is haunting Europe—the specter of Communism. All the Powers of old Europe have entered into a holy alliance to exorcise this specter: Pope and Czar, Metternich and Guizot, French Radicals and German police-spies.

A story about the Jack Spratts of medicine [was] told recently by Dr. Charles H. Best, co-discoverer of insulin. He had been invited to a conference of heart specialists in North America. On the eve of the meeting, out of respect for the fat-clogs-the-arteries theory, the delegates sat down to a special banquet served without fats. It was unpalatable but they all ate it as a duty. Next morning Best looked round the breakfast room and saw these same specialists—all in the 40-60 year old, coronary age group—happily tucking into eggs, bacon, buttered toast and coffee with cream.

Alike fantastic, if too new, or old;
Be not the first by whom the new are try'd,
Not yet the last to lay the old aside.

All frescoes are as high finished as miniatures or enamels, and they are known to be unchangeable; but oil, being a body itself, will drink or absorb very little colour, and changing yellow, and at length brown, destroys every colour it is mixed with, especially every delicate colour. It turns every permanent white to a yellow and brown putty, and has compelled the use of that destroyer of colour, white lead, which, when its protecting oil is evaporated, will become lead again. This is an awful thing to say to oil painters ; they may call it madness, but it is true. All the genuine old little pictures, called cabinet pictures, are in fresco and not in oil. Oil was not used except by blundering ignorance till after Vandyke’s time ; but the art of fresco painting being lost, oil became a fetter to genius and a dungeon to art.

All minds quote. Old and new make the warp and woof of every moment. There is no thread that is not a twist of these two strands.

All of us are interested in our roots. Generally this interest is latent in youth, and grows with age. Until I reached fifty I thought that history of science was a refuge for old scientists whose creative juices had dried up. Now of course I know that I was wrong! As we grow older, we become more interested in the past, in family history, local history, etc. Astronomy is, or was when I started in it, almost a family.

All the old constellations had gone from the sky, however: that slow movement which is imperceptible in a hundred human lifetimes, had long since rearranged them in unfamiliar groupings. But the Milky Way, it seemed to me, was still the same tattered streamer of star-dust as of yore.

Alphonse of Castile is reported to have said that if he had had the making of the universe he would have done it much better. And I think so too. Instead of making a man go through the degradation of faculties and death, he should continually improve with age, and then be translated from this world to a superior planet, where he should begin life with the knowledge gained here, and so on. That would be to my mind, as an old man, a more satisfactory way of conducting affairs

Among the older records, we find chapter after chapter of which we can read the characters, and make out their meaning: and as we approach the period of man’s creation, our book becomes more clear, and nature seems to speak to us in language so like our own, that we easily comprehend it. But just as we begin to enter on the history of physical changes going on before our eyes, and in which we ourselves bear a part, our chronicle seems to fail us—a leaf has been torn out from nature's record, and the succession of events is almost hidden from our eyes.

An idea must not be condemned for being a little shy and incoherent; all new ideas are shy when introduced first among our old ones. We should have patience and see whether the incoherency is likely to wear off or to wear on, in which latter case the sooner we get rid of them the better.

An idea must not be condemned for being a little shy and incoherent; all new ideas are shy when introduced first among our old ones. We should have patience and see whether the incoherency is likely to wear off or to wear on, in which latter case the sooner we get rid of them the better.

An Individual, whatever species it might be, is nothing in the Universe. A hundred, a thousand individuals are still nothing. The species are the only creatures of Nature, perpetual creatures, as old and as permanent as it. In order to judge it better, we no longer consider the species as a collection or as a series of similar individuals, but as a whole independent of number, independent of time, a whole always living, always the same, a whole which has been counted as one in the works of creation, and which, as a consequence, makes only a unity in Nature.

An inventor is simply a fellow who doesn’t take his education too seriously. You see, from the time a person is six years old until he graduates form college he has to take three or four examinations a year. If he flunks once, he is out. But an inventor is almost always failing. He tries and fails maybe a thousand times. It he succeeds once then he’s in. These two things are diametrically opposite. We often say that the biggest job we have is to teach a newly hired employee how to fail intelligently. We have to train him to experiment over and over and to keep on trying and failing until he learns what will work.

An old foundation is worthy of all respect, but it must not take from us the right to build afresh wherever we will.

An old French geometer used to say that a mathematical theory was never to be considered complete till you had made it so clear that you could explain it to the first man you met in the street.

An old medical friend gave me some excellent practical advice. He said: “You will have for some time to go much oftener down steps than up steps. Never mind! win the good opinions of washerwomen and such like, and in time you will hear of their recommendations of you to the wealthier families by whom they are employed.” I did so, and found it succeed as predicted.
[On beginning a medical practice.]

An old paleontological in joke proclaims that mammalian evolution is a tale told by teeth mating to produce slightly altered descendant teeth.

An old saying is “A penny for your thoughts.” The offer is not high enough: some thoughts would not be confessed for a million dollars.

An old Scotch physician, for whom I had a great respect, and whom I frequently met professionally in the city, used to say, as we were entering the patient's room together, 'Weel, Mister Cooper, we ha' only twa things to keep in meend, and they'll searve us for here and herea'ter; one is always to have the fear of the Laird before our ees; that 'ill do for herea'ter; and t'other is to keep your booels open, and that will do for here.'

An old writer says that there are four sorts of readers: “Sponges which attract all without distinguishing; Howre-glasses which receive and powre out as fast; Bagges which only retain the dregges of the spices and let the wine escape, and Sives which retaine the best onely.” A man wastes a great many years before he reaches the ‘sive’ stage.

Anaximander son of Praxiades, of Miletus: he said that the principle and element is the Indefinite, not distinguishing air or water or anything else. … he was the first to discover a gnomon, and he set one up on the Sundials (?) in Sparta, according to Favorinus in his Universal History, to mark solstices and equinoxes; and he also constructed hour indicators. He was the first to draw an outline of earth and sea, but also constructed a [celestial] globe. Of his opinions he made a summary exposition, which I suppose Apollodorus the Athenian also encountered. Apollodorus says in his Chronicles that Anaximander was sixty-four years old in the year of the fifty-eighth Olympiad [547/6 B.C.], and that he died shortly afterwards (having been near his prime approximately during the time of Polycrates, tyrant of Samos).

Ancient stars in their death throes spat out atoms like iron which this universe had never known. ... Now the iron of old nova coughings vivifies the redness of our blood.

Another argument of hope may be drawn from this–that some of the inventions already known are such as before they were discovered it could hardly have entered any man's head to think of; they would have been simply set aside as impossible. For in conjecturing what may be men set before them the example of what has been, and divine of the new with an imagination preoccupied and colored by the old; which way of forming opinions is very fallacious, for streams that are drawn from the springheads of nature do not always run in the old channels.

Another of my hobby-horses is the advantage of ignorance, in that it encourages creativity, both in the young and the old.

Antiqua consuetudo difficulter relinquitur: & ultra proprium videre nemo libenter ducitur.
Old habits are hard to break: and no one is easily led beyond his own point of view.

Any fool can destroy trees. They cannot run away; and if they could, they would still be destroyed,—chased and hunted down as long as fun or a dollar could be got out of their bark hides, branching horns, or magnificent bole backbones. Few that fell trees plant them; nor would planting avail much towards getting back anything like the noble primeval forests. During a man’s life only saplings can be grown, in the place of the old trees—tens of centuries old—that have been destroyed.

As long as museums and universities send out expeditions to bring to light new forms of living and extinct animals and new data illustrating the interrelations of organisms and their environments, as long as anatomists desire a broad comparative basis human for anatomy, as long as even a few students feel a strong curiosity to learn about the course of evolution and relationships of animals, the old problems of taxonomy, phylogeny and evolution will gradually reassert themselves even in competition with brilliant and highly fruitful laboratory studies in cytology, genetics and physiological chemistry.

As Love is too young to know what conscience is, so Truth and Genius are too old to know what definition is.

As regards the co-ordination of all ordinary properties of matter, Rutherford’s model of the atom puts before us a task reminiscent of the old dream of philosophers: to reduce the interpretation of the laws of nature to the consideration of pure numbers.

As the component parts of all new machines may be said to be old[,] it is a nice discriminating judgment, which discovers that a particular arrangement will produce a new and desired effect. ... Therefore, the mechanic should sit down among levers, screws, wedges, wheels, etc. like a poet among the letters of the alphabet, considering them as the exhibition of his thoughts; in which a new arrangement transmits a new idea to the world.

At the Egyptian city of Naucratis there was a famous old god whose name was Theuth; the bird which is called the Ibis was sacred to him, and he was the inventor of many arts, such as arithmetic and calculation and geometry and astronomy and draughts and dice, but his great discovery was the use of letters.

At the entrance to the observatory Stjerneborg located underground, Tycho Brahe built a Ionic portal. On top of this were three sculptured lions. On both sides were inscriptions and on the backside was a longer inscription in gold letters on a porfyr stone: Consecrated to the all-good, great God and Posterity. Tycho Brahe, Son of Otto, who realized that Astronomy, the oldest and most distinguished of all sciences, had indeed been studied for a long time and to a great extent, but still had not obtained sufficient firmness or had been purified of errors, in order to reform it and raise it to perfection, invented and with incredible labour, industry, and expenditure constructed various exact instruments suitable for all kinds of observations of the celestial bodies, and placed them partly in the neighbouring castle of Uraniborg, which was built for the same purpose, partly in these subterranean rooms for a more constant and useful application, and recommending, hallowing, and consecrating this very rare and costly treasure to you, you glorious Posterity, who will live for ever and ever, he, who has both begun and finished everything on this island, after erecting this monument, beseeches and adjures you that in honour of the eternal God, creator of the wonderful clockwork of the heavens, and for the propagation of the divine science and for the celebrity of the fatherland, you will constantly preserve it and not let it decay with old age or any other injury or be removed to any other place or in any way be molested, if for no other reason, at any rate out of reverence to the creator’s eye, which watches over the universe. Greetings to you who read this and act accordingly. Farewell!

At the heart of science is an essential balance between two seemingly contradictory attitudes—an openness to new ideas, no matter how bizarre or counterintuitive they may be, and the most ruthless skeptical scrutiny of all ideas, old and new. This is how deep truths are winnowed from deep nonsense.

At times the mathematician has the passion of a poet or a conqueror, the rigor of his arguments is that of a responsible statesman or, more simply, of a concerned father, and his tolerance and resignation are those of an old sage; he is revolutionary and conservative, skeptical and yet faithfully optimistic.

Beta decay was … like a dear old friend. There would always be a special place in my heart reserved especially for it.

Beware of old Linnaeus,
The Man of the Linden-tree,
So beautiful, bright and early
He brushed away the dews
He found the wicked wild-flowers
All courting there in twos.

Beware of the young Doctor, & the old Barber.

Blessings on Science! When the earth seem’d old,
When Faith grew doting, and the Reason cold,
Twas she discover’d that the world was young,
And taught a language to its lisping tongue:
’Twas she disclosed a future to its view,
And made old knowledge pale before the new.

Blood mixture and the result drop in the racial level is the sole cause of the dying out of old cultures; for men do not perish as a result of lost wars, but by the loss of that force of resistance which is continued only in pure blood. All who are not of good race in this world are chaff.

BODY-SNATCHER, n. A robber of grave-worms. One who supplies the young physicians with that with which the old physicians have supplied the undertaker. 

Broadly speaking, the short words are the best, and the old words are the best of all.

But among all these many departments of research, these many branches of industry, new and old, which are being rapidly expanded, there is one dominating all others in importance—one which is of the greatest significance for the comfort and welfare, not to say for the existence, of mankind, and that is the electrical transmission of power.

But beyond the bright searchlights of science,
Out of sight of the windows of sense,
Old riddles still bid us defiance,
Old questions of Why and of Whence.

But does Man have any “right” to spread through the universe? Man is what he is, a wild animal with the will to survive, and (so far) the ability, against all competition. Unless one accepts that, anything one says about morals, war, politics, you name it, is nonsense. Correct morals arise from knowing what man is, not what do-gooders and well-meaning old Aunt Nellies would like him to be. The Universe will let us know—later—whether or not Man has any “right” to expand through it.

But if anyone, well seen in the knowledge, not onely of Sacred and exotick History, but of Astronomical Calculation, and the old Hebrew Kalendar, shall apply himself to these studies, I judge it indeed difficult, but not impossible for such a one to attain, not onely the number of years, but even, of dayes from the Creation of the World.

But no pursuit at Cambridge was followed with nearly so much eagerness or gave me so much pleasure as collecting beetles. It was the mere passion for collecting, for I did not dissect them, and rarely compared their external characters with published descriptions, but got them named anyhow. I will give a proof of my zeal: one day, on tearing off some old bark, I saw two rare beetles, and seized one in each hand; then I saw a third and new kind, which I could not bear to lose, so that I popped the one which I held in my right hand into my mouth. Alas! it ejected some intensely acrid fluid, which burnt my tongue so that I was forced to spit the beetle out, which was lost, as was the third one.

But of all environments, that produced by man’s complex technology is perhaps the most unstable and rickety. In its present form, our society is not two centuries old, and a few nuclear bombs will do it in.
To be sure, evolution works over long periods of time and two centuries is far from sufficient to breed Homo technikos… .
The destruction of our technological society in a fit of nuclear peevishness would become disastrous even if there were many millions of immediate survivors.
The environment toward which they were fitted would be gone, and Darwin’s demon would wipe them out remorselessly and without a backward glance.

By considering the embryological structure of man - the homologies which he presents with the lower animals - the rudiments which he retains - and the reversions to which he is liable, we can partly recall in imagination the former condition of our early progenitors; and we can approximately place them in their proper position in the zoological series. We thus learnt that man is descended from a hairy quadruped, furnished with a tail and pointed ears, probably arboreal in its habit, and an inhabitant of the Old World. This creature, if its whole structure had been examined by a naturalist, would have been classed among the Quadrumana, as surely as would be the common and still more ancient progenitor of the Old and New World monkeys.

By the worldly standards of public life, all scholars in their work are of course oddly virtuous. They do not make wild claims, they do not cheat, they do not try to persuade at any cost, they appeal neither to prejudice nor to authority, they are often frank about their ignorance, their disputes are fairly decorous, they do not confuse what is being argued with race, politics, sex or age, they listen patiently to the young and to the old who both know everything. These are the general virtues of scholarship, and they are peculiarly the virtues of science.

By the year 2070 we cannot say, or it would be imbecile to do so, that any man alive could understand Shakespearean experience better than Shakespeare, whereas any decent eighteen-year-old student of physics will know more physics than Newton.

Chaos theory is a new theory invented by scientists panicked by the thought that the public were beginning to understand the old ones.

Chemistry has the same quickening and suggestive influence upon the algebraist as a visit to the Royal Academy, or the old masters may be supposed to have on a Browning or a Tennyson. Indeed it seems to me that an exact homology exists between painting and poetry on the one hand and modern chemistry and modern algebra on the other. In poetry and algebra we have the pure idea elaborated and expressed through the vehicle of language, in painting and chemistry the idea enveloped in matter, depending in part on manual processes and the resources of art for its due manifestation.

Consider the plight of a scientist of my age. I graduated from the University of California at Berkeley in 1940. In the 41 years since then the amount of biological information has increased 16 fold; during these 4 decades my capacity to absorb new information has declined at an accelerating rate and now is at least 50% less than when I was a graduate student. If one defines ignorance as the ratio of what is available to be known to what is known, there seems no alternative to the conclusion that my ignorance is at least 25 times as extensive as it was when I got my bachelor’s degree. Although I am sure that my unfortunate condition comes as no surprise to my students and younger colleagues, I personally find it somewhat depressing. My depression is tempered, however, by the fact that all biologists, young or old, developing or senescing, face the same melancholy situation because of an interlocking set of circumstances.

Creating a new theory is not like destroying an old barn and erecting a skyscraper in its place. It is rather like climbing a mountain, gaining new and wider views, discovering unexpected connections between our starting point and its rich environment. But the point from which we started out still exists and can be seen, although it appears smaller and forms a tiny part of our broad view gained by the mastery of the obstacles on our adventurous way up.

Darwin's Origin of Species had come into the theological world like a plough into an ant-hill. Everywhere those thus rudely awakened from their old comfort and repose had swarmed forth angry and confused. Reviews, sermons, books light and heavy, came flying at the new thinker from all sides.

Darwin's theory was received in Russia with profound sympathy. While in Western Europe it met firmly established old traditions which it had first to overcome, in Russia its appearance coincided with the awakening of our society after the Crimean War and here it immediately received the status of full citizenship and ever since has enjoyed widespread popularity.

Disease is largely a removable evil. It continues to afflict humanity, not only because of incomplete knowledge of its causes and lack of individual and public hygiene, but also because it is extensively fostered by harsh economic and industrial conditions and by wretched housing in congested communities. ... The reduction of the death rate is the principal statistical expression and index of human social progress. It means the saving and lengthening of lives of thousands of citizens, the extension of the vigorous working period well into old age, and the prevention of inefficiency, misery, and suffering. These advances can be made by organized social effort. Public health is purchasable. (1911)

Diseased nature oftentimes breaks forth
In strange eruptions: oft the teeming earth
Is with a kind of colic pinch’d and vex’d
By the imprisoning of unruly wind
Within her womb; which, for enlargement striving,
Shakes the old beldam earth, and topples down
Steeples and moss-grown towers.

Drunkenness, the ruin of reason, the destruction of strength, premature old age, momentary death.

During the school period the student has been mentally bending over his desk; at the University he should stand up and look around. For this reason it is fatal if the first year at the University be frittered away in going over the old work in the old spirit. At school the boy painfully rises from the particular towards glimpses at general ideas; at the University he should start from general ideas and study their applications to concrete cases.

Each new scientific development is due to the pressure of some social need. Of course … insatiable curiosity … is still nothing but a response either to an old problem of nature, or to one arising from new social circumstances.

Einstein, twenty-six years old, only three years away from crude privation, still a patent examiner, published in the Annalen der Physik in 1905 five papers on entirely different subjects. Three of them were among the greatest in the history of physics. One, very simple, gave the quantum explanation of the photoelectric effect—it was this work for which, sixteen years later, he was awarded the Nobel prize. Another dealt with the phenomenon of Brownian motion, the apparently erratic movement of tiny particles suspended in a liquid: Einstein showed that these movements satisfied a clear statistical law. This was like a conjuring trick, easy when explained: before it, decent scientists could still doubt the concrete existence of atoms and molecules: this paper was as near to a direct proof of their concreteness as a theoretician could give. The third paper was the special theory of relativity, which quietly amalgamated space, time, and matter into one fundamental unity.
This last paper contains no references and quotes no authority. All of them are written in a style unlike any other theoretical physicist’s. They contain very little mathematics. There is a good deal of verbal commentary. The conclusions, the bizarre conclusions, emerge as though with the greatest of ease: the reasoning is unbreakable. It looks as though he had reached the conclusions by pure thought, unaided, without listening to the opinions of others. To a surprisingly large extent, that is precisely what he had done.

EXPERIENCE, n. The wisdom that enables us to recognize as an undesirable old acquaintance the folly that we have already embraced.

Faraday thinks from day to day, against a background of older thinking, and anticipating new facts of tomorrow. In other words, he thinks in three dimensions of time; past, present, and future.

Fires from beneath, and meteors from above,
Portentous, unexampled, unexplain'd,
Have kindled beacons in the skies; and th' old
And crazy earth has had her shaking fits
More frequent, and foregone her usual rest.
Is it a time to wrangle, when the props
And pillars of our planet seem to fail,
And nature, with a dim and sickly eye,
To wait the close of all?
Alluding the meteors of 17 Aug 1883.

Following the light of the sun, we left the Old World.

For my own part I would as soon be descended from that heroic little monkey, who braved his dreaded enemy in order to save the life of his keeper; or from that old baboon, who, descending from the mountains, carried away in triumph his young comrade from a crowd of astonished dogs—as from a savage who delights to torture his enemies, offers up bloody sacrifices, practices infanticide without remorse, treats his wives like slaves, knows no decency, and is haunted by the grossest superstitions.

For myself, I found that I was fitted for nothing so well as for the study of Truth; as having a mind nimble and versatile enough to catch the resemblances of things (which is the chief point) , and at the same time steady enough to fix and distinguish their subtler differences; as being gifted by nature with desire to seek, patience to doubt, fondness to meditate, slowness to assert, readiness to reconsider, carefulness to dispose and set in order; and as being a man that neither affects what is new nor admires what is old, and that hates every kind of imposture. So I thought my nature had a kind of familiarity and relationship with Truth.

For out of old feldes, as men seith,
Cometh al this newe corn fro yere to yere;
And out of olde bokes, in good feith,
Cometh al this newe science that men lere.

FORTRAN —’the infantile disorder’—, by now nearly 20 years old, is hopelessly inadequate for whatever computer application you have in mind today: it is now too clumsy, too risky, and too expensive to use. PL/I —’the fatal disease’— belongs more to the problem set than to the solution set. It is practically impossible to teach good programming to students that have had a prior exposure to BASIC: as potential programmers they are mentally mutilated beyond hope of regeneration. The use of COBOL cripples the mind; its teaching should, therefore, be regarded as a criminal offence. APL is a mistake, carried through to perfection. It is the language of the future for the programming techniques of the past: it creates a new generation of coding bums.

FORTRAN, ‘the infantile disorder’, by now nearly 20 years old, is hopelessly inadequate for whatever computer application you have in mind today: it is now too clumsy, too risky, and too expensive to use.

From our home on the Earth, we look out into the distances and strive to imagine the sort of world into which we were born. Today, we have reached far into space. Our immediate neighborhood we know rather intimately. But with increasing distance our knowledge fades … The search will continue. The urge is older than history. It is not satisfied and will not be suppressed.

Gentlemen, there is such a chaos in our therapeutics that we ought to be thankful for any good advice, whether it comes from an old woman, a shepherd, a blacksmith, or even a Homeopath.

Geometrical axioms are neither synthetic a priori conclusions nor experimental facts. They are conventions: our choice, amongst all possible conventions, is guided by experimental facts; but it remains free, and is only limited by the necessity of avoiding all contradiction. ... In other words, axioms of geometry are only definitions in disguise.
That being so what ought one to think of this question: Is the Euclidean Geometry true?
The question is nonsense. One might as well ask whether the metric system is true and the old measures false; whether Cartesian co-ordinates are true and polar co-ordinates false.

Given one has before oneself a strong, healthy, youth rich in spirited blood and a powerless, weak, cachectic old man scarcely capable of breathing. If now the physician wishes to practise the rejuvenating art on the latter, he should make silver tubes which fit into each other: open then the artery of the healthy person and introduce one of the tubes into it and fasten it into the artery; thereupon he opens also the artery of the ill person...
[First detailed description of blood transfusion (1615)]

Go, wondrous creature, mount where science guides.
Go, measure earth, weigh air, and state the tides;
Instruct the planets in what orbs to run,
Correct old Time, and regulate the sun;
Go, teach Eternal Wisdom how to rule,
Then drop into thyself and be a fool.

Go, wondrous creature! mount where Science guides,
Go, measure earth, weigh air, and state the tides;
Instruct the planets in what orbs to run,
Correct old Time, and regulate the Sun.

Gold and iron at the present day, as in ancient times, are the rulers of the world; and the great events in the world of mineral art are not the discovery of new substances, but of new and rich localities of old ones.

Good, old-fashioned common sense iz one ov the hardest things in the world to out-wit, out-argy, or beat in enny way, it iz az honest az a loaf ov good domestik bread, alwus in tune, either hot from the oven or 8 days old.

Great thinkers build their edifices with subtle consistency. We do our intellectual forebears an enormous disservice when we dismember their visions and scan their systems in order to extract a few disembodied ‘gems’–thoughts or claims still accepted as true. These disarticulated pieces then become the entire legacy of our ancestors, and we lose the beauty and coherence of older systems that might enlighten us by their unfamiliarity–and their consequent challenge in our fallible (and complacent) modern world.

Having someone wonder where you are when you don’t come home at night is a very old human need.

He (Anaxagoras) is said to have been twenty years old at the time of Xerxes' crossing, and to have lived to seventy-two. Apollodorus says in his Chronicles that he was born in the seventieth Olympiad (500-497 B.C.) and died in the first year of the eighty-eighth (428/7). He began to be a philosopher at Athens in the archonship of Callias (456/5), at the age of twenty, as Demetrius Phalereus tells us in his Register of Archons, and they say he spent thirty years there. … There are different accounts given of his trial. Sotion, in his Succession of Philosophers, says that he was prosecuted by Cleon for impiety, because he maintained that the sun was a red hot mass of metal, and after that Pericles, his pupil, had made a speech in his defence, he was fined five talents and exiled. Satyrus in his Uves, on the other hand, says that the charge was brought by Thucydides in his political campaign against Pericles; and he adds that the charge was not only for the impiety but for Medism as well; and he was condemned to death in his absence. ... Finally he withdrew to Lampsacus, and there died. It is said that when the rulers of the city asked him what privilege he wished to be granted, he replied that the children should be given a holiday every year in the month in which he died. The custom is preserved to the present day. When he died the Lampsacenes buried him with full honours.

He was 40 yeares old before he looked on Geometry; which happened accidentally. Being in a Gentleman's Library, Euclid's Elements lay open, and 'twas the 47 El. Libri 1 [Pythagoras' Theorem]. He read the proposition. By G-, sayd he (he would now and then sweare an emphaticall Oath by way of emphasis) this is impossible! So he reads the Demonstration of it, which referred him back to such a Proposition; which proposition he read. That referred him back to another, which he also read. Et sic deinceps [and so on] that at last he was demonstratively convinced of that trueth. This made him in love with Geometry .
Of Thomas Hobbes, in 1629.

He who would know what geometry is, must venture boldly into its depths and learn to think and feel as a geometer. I believe that it is impossible to do this, and to study geometry as it admits of being studied and am conscious it can be taught, without finding the reason invigorated, the invention quickened, the sentiment of the orderly and beautiful awakened and enhanced, and reverence for truth, the foundation of all integrity of character, converted into a fixed principle of the mental and moral constitution, according to the old and expressive adage “abeunt studia in mores”.

His work was so great that it cannot be compassed in a few words. His death is one of the greatest losses ever to occur to British science.
Describing Ernest Rutherford upon his death at age 66. Thomson, then 80 years old, was once his teacher.

History is primarily a socio-psychological science. In the conflict between the old and the new tendencies in historical investigation... we are at the turn of the stream, the parting of the ways in historical science.

Hot things, sharp things, sweet things, cold things
All rot the teeth, and make them look like old things.