Chemistry has the same quickening and suggestive influence upon the algebraist as a visit to the Royal Academy, or the old masters may be supposed to have on a Browning or a Tennyson. Indeed it seems to me that an exact homology exists between painting and poetry on the one hand and modern chemistry and modern algebra on the other. In poetry and algebra we have the pure idea elaborated and expressed through the vehicle of language, in painting and chemistry the idea enveloped in matter, depending in part on manual processes and the resources of art for its due manifestation.

Decades spent in contact with science and its vehicles have directed my mind and senses to areas beyond their reach. I now see scientific accomplishments as a path, not an end; a path leading to and disappearing in mystery. Science, in fact, forms many paths branching from the trunk of human progress; and on every periphery they end in the miraculous. Following these paths far enough, one must eventually conclude that science itself is a miracle—like the awareness of man arising from and then disappearing in the apparent nothingness of space. Rather than nullifying religion and proving that “God is dead,” science enhances spiritual values by revealing the magnitudes and minitudes—from cosmos to atom—through which man extends and of which he is composed.

Humanity is about to learn that a lunatic (touched by the moon) is not a crazy man but one so sane, well-informed, well-coordinated, self-disciplined, cooperative and fearless as to be the first earthian human to have been ferried to a physical landing upon the moon, and thereafter to have been returned safely to reboard his mother space vehicle earth.

I have decided today that the United States should proceed at once with the development of an entirely new type of space transportation system designed to help transform the space frontier of the 1970s into familiar territory, easily accessible for human endeavor in the 1980s and ’90s. This system will center on a space vehicle that can shuttle repeatedly from Earth to orbit and back. It will revolutionize transportation into near space, by routinizing it. It will take the astronomical costs out of astronautics. In short, it will go a long way toward delivering the rich benefits of practical space utilization and the valuable spin-offs from space efforts into the daily lives of Americans and all people.

If there had been a computer in 1872 it would have predicted that by now there would be so many horse-drawn vehicles that the entire surface of the earth would be ten feet deep in horse manure.

Science affects the average man and woman in two ways already. He or she benefits by its application driving a motor-car or omnibus instead of a horse-drawn vehicle, being treated for disease by a doctor or surgeon rather than a witch, and being killed with an automatic pistol or shell in place of a dagger or a battle-axe.

Since the days of Hippocrates, our father, the aphorism has been the literary vehicle of the doctor… Laymen have stolen the trick from time to time, but the aphorism remains the undisputed contribution of the doctor to literature.
[Coauthor with Ray Marr]

The messages that DNA molecules contain are all but eternal when seen against the time scale of individual lifetimes. The lifetimes of DNA messages (give or take a few mutations) are measured in units ranging from millions of years to hundreds of millions of years; or, in other words, ranging from 10,000 individual lifetimes to a trillion individual lifetimes. Each individual organism should be seen as a temporary vehicle, in which DNA messages spend a tiny fraction of their geological lifetimes.

The vehicle explodes, literally explodes, off the pad. The simulator shakes you a little bit, but the actual liftoff shakes your entire body and soul.

There is another approach to the extraterrestrial hypothesis of UFO origins. This assessment depends on a large number of factors about which we know little, and a few about which we know literally nothing. I want to make some crude numerical estimate of the probability that we are frequently visited by extraterrestrial beings.
Now, there is a range of hypotheses that can be examined in such a way. Let me give a simple example: Consider the Santa Claus hypothesis, which maintains that, in a period of eight hours or so on December 24-25 of each year, an outsized elf visits one hundred million homes in the United States. This is an interesting and widely discussed hypothesis. Some strong emotions ride on it, and it is argued that at least it does no harm.
We can do some calculations. Suppose that the elf in question spends one second per house. This isn't quite the usual picture—“Ho, Ho, Ho,” and so on—but imagine that he is terribly efficient and very speedy; that would explain why nobody ever sees him very much-only one second per house, after all. With a hundred million houses he has to spend three years just filling stockings. I have assumed he spends no time at all in going from house to house. Even with relativistic reindeer, the time spent in a hundred million houses is three years and not eight hours. This is an example of hypothesis-testing independent of reindeer propulsion mechanisms or debates on the origins of elves. We examine the hypothesis itself, making very straightforward assumptions, and derive a result inconsistent with the hypothesis by many orders of magnitude. We would then suggest that the hypothesis is untenable.
We can make a similar examination, but with greater uncertainty, of the extraterrestrial hypothesis that holds that a wide range of UFOs viewed on the planet Earth are space vehicles from planets of other stars.

We are survival machines—robot vehicles blindly programmed to preserve the selfish molecules known as genes. This is a truth which still fills me with astonishment.