Chemistry is the study of material transformations. Yet a knowledge of the rate, or time dependence, of chemical change is of critical importance for the successful synthesis of new materials and for the utilization of the energy generated by a reaction. During the past century it has become clear that all macroscopic chemical processes consist of many elementary chemical reactions that are themselves simply a series of encounters between atomic or molecular species. In order to understand the time dependence of chemical reactions, chemical kineticists have traditionally focused on sorting out all of the elementary chemical reactions involved in a macroscopic chemical process and determining their respective rates.

Conservation is the foresighted utilization, preservation. And/or renewal of forest, waters, lands and minerals, for the greatest good of the greatest number for the longest time.

Engineering is an activity other than purely manual and physical work which brings about the utilization of the materials and laws of nature for the good of humanity.

Engineering is the art of construction; but to limit it to this would be to restrict its meaning much within the range of the ordinary use of the word. In a broader sense, engineering includes all operations whose object is the utilization of the forces of nature in the interests of man.

Engineering is the art or science of utilizing, directing or instructing others in the utilization of the principles, forces, properties and substance of nature in the production, manufacture, construction, operation and use of things ... or of means, methods, machines, devices and structures ...

Engineering is the professional and systematic application of science to the efficient utilization of natural resources to produce wealth.

Engineering is the science of economy, of conserving the energy, kinetic and potential, provided and stored up by nature for the use of man. It is the business of engineering to utilize this energy to the best advantage, so that there may be the least possible waste.

I have decided today that the United States should proceed at once with the development of an entirely new type of space transportation system designed to help transform the space frontier of the 1970s into familiar territory, easily accessible for human endeavor in the 1980s and ’90s. This system will center on a space vehicle that can shuttle repeatedly from Earth to orbit and back. It will revolutionize transportation into near space, by routinizing it. It will take the astronomical costs out of astronautics. In short, it will go a long way toward delivering the rich benefits of practical space utilization and the valuable spin-offs from space efforts into the daily lives of Americans and all people.

In so far as such developments utilise the natural energy running to waste, as in water power, they may be accounted as pure gain. But in so far as they consume the fuel resources of the globe they are very different. The one is like spending the interest on a legacy, and the other is like spending the legacy itself. ... [There is] a still hardly recognised coming energy problem.

It is not Cayley’s way to analyze concepts into their ultimate elements. … But he is master of the empirical utilization of the material: in the way he combines it to form a single abstract concept which he generalizes and then subjects to computative tests, in the way the newly acquired data are made to yield at a single stroke the general comprehensive idea to the subsequent numerical verification of which years of labor are devoted. Cayley is thus the natural philosopher among mathematicians.

It will be noticed that the fundamental theorem proved above bears some remarkable resemblances to the second law of thermodynamics. Both are properties of populations, or aggregates, true irrespective of the nature of the units which compose them; both are statistical laws; each requires the constant increase of a measurable quantity, in the one case the entropy of a physical system and in the other the fitness, measured by m, of a biological population. As in the physical world we can conceive the theoretical systems in which dissipative forces are wholly absent, and in which the entropy consequently remains constant, so we can conceive, though we need not expect to find, biological populations in which the genetic variance is absolutely zero, and in which fitness does not increase. Professor Eddington has recently remarked that “The law that entropy always increases—the second law of thermodynamics—holds, I think, the supreme position among the laws of nature.” It is not a little instructive that so similar a law should hold the supreme position among the biological sciences. While it is possible that both may ultimately be absorbed by some more general principle, for the present we should note that the laws as they stand present profound differences—-(1) The systems considered in thermodynamics are permanent; species on the contrary are liable to extinction, although biological improvement must be expected to occur up to the end of their existence. (2) Fitness, although measured by a uniform method, is qualitatively different for every different organism, whereas entropy, like temperature, is taken to have the same meaning for all physical systems. (3) Fitness may be increased or decreased by changes in the environment, without reacting quantitatively upon that environment. (4) Entropy changes are exceptional in the physical world in being irreversible, while irreversible evolutionary changes form no exception among biological phenomena. Finally, (5) entropy changes lead to a progressive disorganization of the physical world, at least from the human standpoint of the utilization of energy, while evolutionary changes are generally recognized as producing progressively higher organization in the organic world.

Man must at all costs overcome the Earth’s gravity and have, in reserve, the space at least of the Solar System. All kinds of danger wait for him on the Earth… We are talking of disaster that can destroy the whole of mankind or a large part of it… For instance, a cloud of bolides [meteors] or a small planet a few dozen kilometers in diameter could fall on the Earth, with such an impact that the solid, liquid or gaseous blast produced by it could wipe off the face of the Earth all traces of man and his buildings. The rise of temperature accompanying it could alone scorch or kill all living beings… We are further compelled to take up the struggle against gravity, and for the utilization of celestial space and all its wealth, because of the overpopulation of our planet. Numerous other terrible dangers await mankind on the Earth, all of which suggest that man should look for a way into the Cosmos. We have said a great deal about the advantages of migration into space, but not all can be said or even imagined.

Obviously we biologists should fit our methods to our materials. An interesting response to this challenge has been employed particularly by persons who have entered biology from the physical sciences or who are distressed by the variability in biology; they focus their research on inbred strains of genetically homogeneous laboratory animals from which, to the maximum extent possible, variability has been eliminated. These biologists have changed the nature of the biological system to fit their methods. Such a bold and forthright solution is admirable, but it is not for me. Before I became a professional biologist, I was a boy naturalist, and I prefer a contrasting approach; to change the method to fit the system. This approach requires that one employ procedures which allow direct scientific utilization of the successful long-term evolutionary experiments which are documented by the fascinating diversity and variability of the species of animals which occupy the earth. This is easy to say and hard to do.

Science has gone a long way toward helping man to free himself from the burden of hard labor; yet, science itself is not a liberator. It creates means, not goals. It is up to men to utilize those means to achieve reasonable goals.

The events of the past few years have led to a critical examination of the function of science in society. It used to be believed that the results of scientific investigation would lead to continuous progressive improvements in conditions of life; but first the War and then the economic crisis have shown that science can be used as easily for destructive and wasteful purposes, and voices have been raised demanding the cessation of scientific research as the only means of preserving a tolerable civilization. Scientists themselves, faced with these criticisms, have been forced to consider, effectively for the first time, how the work they are doing is connected around them. This book is an attempt to analyse this connection; to investigate how far scientists, individually and collectively, are responsible for this state of affairs, and to suggest what possible steps could be taken which would lead to a fruitful and not to a destructive utilization of science.

The key to the utilization of atomic energy for world peace will be found in the will of all people to restrict its use for the betterment of mankind.