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Who said: “I have no satisfaction in formulas unless I feel their arithmetical magnitude.”
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Reaction Quotes (59 quotes)

'Tis a short sight to limit our faith in laws to those of gravity, of chemistry, of botany, and so forth. Those laws do not stop where our eyes lose them, but push the same geometry and chemistry up into the invisible plane of social and rational life, so that, look where we will, in a boy's game, or in the strifes of races, a perfect reaction, a perpetual judgment keeps watch and ward.
From 'Worship', The Conduct of Life (1860) collected in The Complete Works of Ralph Waldo Emerson (1866), Vol.2, 401.
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... every chemical combination is wholly and solely dependent on two opposing forces, positive and negative electricity, and every chemical compound must be composed of two parts combined by the agency of their electrochemical reaction, since there is no third force. Hence it follows that every compound body, whatever the number of its constituents, can be divided into two parts, one of which is positively and the other negatively electrical.
Essai sur la théorie des proportions chemiques (1819), 98. Quoted by Henry M. Leicester in article on Bessel in Charles Coulston Gillespie (editor), Dictionary of Scientific Biography (1981), Vol. 2, 94.
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Die Welt der chemischen Vorgänge gleicht einer Bühne, auf welcher sich in unablässiger Aufeinanderfolge Scene um Scene abspielt. Die handelnden Personen auf ihr sind die Elemente.
The world of chemical reactions is like a stage, on which scene after scene is ceaselessly played. The actors on it are the elements.
Original German quote in Mary Elvira Weeks, The Discovery of the Elements (1934), 2, citing Winkler, 'Ueber die Entdeckung neuer Elemente im Verlaufe der letzten fünfundzwanzig Jahre," Ber. (Jan 1897), 30, 13. Translation in Mary Elvira Weeks and Henry M. Leicester (ed.)The Discovery of the Elements (6th ed. 1956), 3.
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Mi è impossibile cingere i fianchi di una ragazza con il mio braccio destro e serrare il suo sorriso nella mia mano sinistra, per poi tentare di studiare i due oggetti separatamente. Allo stesso modo, non ci è possibile separare la vita dalla materia vivente, allo scopo di studiare la sola materia vivente e le sue reazioni. Inevitabilmente, studiando la materia vivente e le sue reazioni, studiamo la vita stessa.
It is impossible to encircle the hips of a girl with my right arm and hold her smile in my left hand, then proceed to study the two items separately. Similarly, we can not separate life from living matter, in order to study only living matter and its reactions. Inevitably, studying living matter and its reactions, we study life itself
In The Nature of Life (1948).
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Sed tamen salis petrae. VI. Part V. NOV. CORVLI. ET V. sulphuris, et sic facies toniitrum et coruscationem: sic facies artificium.
But, however, of saltpetre take six parts, live of young willow (charcoal), and five of sulphur, and so you will make thunder and lightning, and so you will turn the trick.
Bacon’s recipe for Gunpowder, partly expressed as an anagram in the original Latin.
Roger Bacon's Letter Concerning the Marvelous Power of Art and of Nature and Concerning the Nullity of Magic, trans. T. L. Davis (1922), 48.
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A drop of old tuberculin, which is an extract of tubercle bacilli, is put on the skin and then a small superficial scarification is made by turning, with some pressure, a vaccination lancet on the surface of the skin. The next day only those individuals show an inflammatory reaction at the point of vaccination who have already been infected with tuberculosis, whereas the healthy individuals show no reaction at all. Every time we find a positive reaction, we can say with certainty that the child is tuberculous.
'The Relation of Tuberculosis to Infant Mortality', read at the third mid-year meeting of the American Academy of Medicine, New Haven, Conn, (4 Nov 1909). In Bulletin of the American Academy of Medicine (1910), 11, 75.
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About eight days ago I discovered that sulfur in burning, far from losing weight, on the contrary, gains it; it is the same with phosphorus; this increase of weight arises from a prodigious quantity of air that is fixed during combustion and combines with the vapors. This discovery, which I have established by experiments, that I regard as decisive, has led me to think that what is observed in the combustion of sulfur and phosphorus may well take place in the case of all substances that gain in weight by combustion and calcination; and I am persuaded that the increase in weight of metallic calxes is due to the same cause... This discovery seems to me one of the most interesting that has been made since Stahl and since it is difficult not to disclose something inadvertently in conversation with friends that could lead to the truth I have thought it necessary to make the present deposit to the Secretary of the Academy to await the time I make my experiments public.
Sealed note deposited with the Secretary of the French Academy 1 Nov 1772. Oeuvres de Lavoisier, Correspondance, Fasc. II. 1770-75 (1957), 389-90. Adapted from translation by A. N. Meldrum, The Eighteenth-Century Revolution in Science (1930), 3.
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Among those whom I could never pursuade to rank themselves with idlers, and who speak with indignation of my morning sleeps and nocturnal rambles, one passes the day in catching spiders, that he may count their eyes with a microscope; another exhibits the dust of a marigold separated from the flower with a dexterity worthy of Leuwenhoweck himself. Some turn the wheel of electricity; some suspend rings to a lodestone, and find that what they did yesterday, they can do again to-day.—Some register the changes of the wind, and die fully convinced that the wind is changeable.—There are men yet more profound, who have heard that two colorless liquors may produce a color by union, and that two cold bodies will grow hot of they are mingled: they mingle them, and produce the effect expected, say it is strange, and mingle them again.
In Tryon Edwards, A Dictionary of Thoughts (1908), 243.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth's surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.
In Life Itself: Its Origin and Nature (1981), 88.
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And by the influence of heat, light, and electrical powers, there is a constant series of changes [in animal and vegetal substances]; matter assumes new forms, the destruction of one order of beings tends to the conservation of another, solution and consolidation, decay and renovation, are connected, and whilst the parts of the system, continue in a state of fluctuation and change, the order and harmony of the whole remain unalterable.
The Elements of Agricultural Chemistry (1813), in J. Davy (ed.) The Collected Works of Sir Humphry Davy(1839-40), Vol 7, 182.
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Chemistry is the study of material transformations. Yet a knowledge of the rate, or time dependence, of chemical change is of critical importance for the successful synthesis of new materials and for the utilization of the energy generated by a reaction. During the past century it has become clear that all macroscopic chemical processes consist of many elementary chemical reactions that are themselves simply a series of encounters between atomic or molecular species. In order to understand the time dependence of chemical reactions, chemical kineticists have traditionally focused on sorting out all of the elementary chemical reactions involved in a macroscopic chemical process and determining their respective rates.
'Molecular Beam Studies of Elementary Chemical Processes', Nobel Lecture, 8 Dec 1986. In Nobel Lectures: Chemistry 1981-1990 (1992), 320.
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Clinical ecology [is] a new branch of medicine aimed at helping people made sick by a failure to adapt to facets of our modern, polluted environment. Adverse reactions to processed foods and their chemical contaminants, and to indoor and outdoor air pollution with petrochemicals, are becoming more and more widespread and so far these reactions are being misdiagnosed by mainstream medical practitioners and so are not treated effectively.
Quoted in article 'Richard Mackarness', Contemporary Authors Online (2002).
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Do not great Bodies conserve their heat the longest, their parts heating one another, and may not great dense and fix'd Bodies, when heated beyond a certain degree, emit Light so copiously, as by the Emission and Re-action of its Light, and the Reflexions and Refractions of its Rays within its Pores to grow still hotter, till it comes to a certain period of heat, such as is that of the Sun?
Opticks (1704), Book 3, Query II, 135.
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Even the humblest creature has to know how to react to the difference between food and toxin if it's to survive. ... Life and some level of intelligent behavior—discerning and doing what's best for one's survival—appear to go hand in hand.
In Life Everywhere: the Maverick Science of Astrobiology (2002), 140.
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Force, then, is Force, but mark you! Not a thing,
Only a Vector;
Thy barbèd arrows now have lost their sting,
Impotent spectre!
Thy reign, O force! is over. Now no more
Heed we thine action;
Repulsion leaves us where we were before,
So does attraction.
Both Action and Reaction now are gone.
Just ere they vanished,
Stress joined their hands in peace, and made them one;
Then they were banished....
Reproduced in Bruce Clarke, Energy Forms: Allegory and Science in the Era of Classical Thermodynamics (2001), 20-21. In his parody of Shelley's Prometheus Unbound, Maxwell presents Newton's laws of motion updated into axioms of energy.
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I feel like a white granular mass of amorphous crystals—my formula appears to be isomeric with Spasmotoxin. My aurochloride precipitates into beautiful prismatic needles. My Platinochloride develops octohedron crystals,—with fine blue florescence. My physiological action is not indifferent. One millionth of a grain injected under the skin of a frog produced instantaneous death accompanied by an orange blossom odor. The heart stopped in systole. A base—L3H9NG4—offers analogous reaction to phosmotinigstic acid.
In letter to George M. Gould (1889), collected in Elizabeth Bisland The Writings of Lafcadio Hearn (1922), Vol. 14, 89.
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I think it is a sad reflection on our civilization that while we can and do measure the temperature in the atmosphere of Venus we do not know what goes on inside our soufflés.
[Remark made while demonstrating the progress of cooking a Soufflé à la Chartreuse, demonstrating its progress with thermocouples and chart recorders.]
Friday Evening Discourse at the Royal Institution, ‘The Physicist in the Kitchen’. In Proceedings of the Royal Institution (1969), 42/199, 451–67. Cited in article on Kurti by Ralph G. Scurlock in Oxford Dictionary of National Biography.
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I watched Baeyer activating magnesium with iodine for a difficult Grignard reaction; it was done in a test tube, which he watched carefully as he moved it gently by hand over a flame for three quarters of an hour. The test tube was the apparatus to Baeyer.
In Richard Willstätter, Arthur Stoll (ed. of the original German) and Lilli S. Hornig (trans.), From My Life: The Memoirs of Richard Willstätter (1958), 140.
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I will now direct the attention of scientists to a previously unnoticed cause which brings about the metamorphosis and decomposition phenomena which are usually called decay, putrefaction, rotting, fermentation and moldering. This cause is the ability possessed by a body engaged in decomposition or combination, i.e. in chemical action, to give rise in a body in contact with it the same ability to undergo the same change which it experiences itself.
Annalen der Pharmacie 1839, 30, 262. Trans. W. H. Brock.
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I would like to start by emphasizing the importance of surfaces. It is at a surface where many of our most interesting and useful phenomena occur. We live for example on the surface of a planet. It is at a surface where the catalysis of chemical reactions occur. It is essentially at a surface of a plant that sunlight is converted to a sugar. In electronics, most if not all active circuit elements involve non-equilibrium phenomena occurring at surfaces. Much of biology is concerned with reactions at a surface.
'Surface properties of semiconductors', Nobel Lecture (11 Dec 1956). In Nobel Lectures, Physics 1942-1962 (1967), 377.
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If you free yourself from the conventional reaction to a quantity like a million years, you free yourself a bit from the boundaries of human time. And then in a way you do not live at all, but in another way you live forever.
Basin and Range
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In deriving a body from the water type I intend to express that to this body, considered as an oxide, there corresponds a chloride, a bromide, a sulphide, a nitride, etc., susceptible of double compositions, or resulting from double decompositions, analogous to those presented by hydrochloric acid, hydrobromic acid, sulphuretted hydrogen, ammonia etc., or which give rise to the same compounds. The type is thus the unit of comparison for all the bodies which, like it, are susceptible of similar changes or result from similar changes.
Traité de Chimie Organique, 1856, 4, 587. Trans. J. R. Partington, A History of Chemistry, (1970), Vol. 4, 456.
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In every combustion there is disengagement of the matter of fire or of light. A body can burn only in pure air [oxygen]. There is no destruction or decomposition of pure air and the increase in weight of the body burnt is exactly equal to the weight of air destroyed or decomposed. The body burnt changes into an acid by addition of the substance that increases its weight. Pure air is a compound of the matter of fire or of light with a base. In combustion the burning body removes the base, which it attracts more strongly than does the matter of heat, which appears as flame, heat and light.
'Memoire sur la combustion en général', Mémoires de l'Académie des Sciences, 1777, 592. Reprinted in Oeuvres de Lavoisier (1864), Vol. 2, 225-33, trans. M. P. Crosland.
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In the dog two conditions were found to produce pathological disturbances by functional interference, namely, an unusually acute clashing of the excitatory and inhibitory processes, and the influence of strong and extraordinary stimuli. In man precisely similar conditions constitute the usual causes of nervous and psychic disturbances. Different conditions productive of extreme excitation, such as intense grief or bitter insults, often lead, when the natural reactions are inhibited by the necessary restraint, to profound and prolonged loss of balance in nervous and psychic activity.
Ivan Pavlov and G. V. Anrep (ed., trans.), Conditioned Reflexes—An Investigation of the Physiological Activity of the Cerebral Cortex (1927), 397.
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It cannot, of course, be stated with absolute certainty that no elements can combine with argon; but it appears at least improbable that any compounds will be formed.
[This held true for a century, until in Aug 2000, the first argon compound was formed, argon fluorohydride, HArF, but stable only below 40 K (−233 °C).]
Gases of the Atmosphere (1896), 193. Referenced in William H. Brock, The Chemical Tree: A History of Chemistry (2000), 339 and 671.
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It is a very strange thing to reflect that but for the invention of Professor Haber the Germans could not have continued the War after their original stack of nitrates was exhausted. The invention of this single man has enabled them, utilising the interval in which their accumulations were used up, not only to maintain an almost unlimited supply of explosives for all purposes, but to provide amply for the needs of agriculture in chemical manures. It is a remarkable fact, and shows on what obscure and accidental incidents the fortunes of possible the whole world may turn in these days of scientific discovery.
[During World War I, Fritz Haber and Karl Bosch invented a large scale process to cause the direct combination of hydrogen and nitrogen gases to chemically synthesize ammonia, thus providing a replacement for sodium nitrate in the manufacture of explosives and fertilizers.]
Parliamentary debate (25 Apr 1918). In Winston Churchill, Richard Langworth (ed.), Churchill by Himself: The Definitive Collection of Quotations‎ (2008), 469. by Winston Churchill, Richard Langworth
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It is, I believe, justifiable to make the generalization that anything an organic chemist can synthesize can be made without him. All he does is increase the probability that given reactions will 'go.' So it is quite reasonable to assume that given sufficient time and proper conditions, nucleotides, amino acids, proteins, and nucleic acids will arise by reactions that, though less probable, are as inevitable as those by which the organic chemist fulfills his predictions. So why not self-duplicating virus-like systems capable of further evolution?
The Place of Genetics in Modern Biology (1959),18.
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It seems to me that the view toward which we are tending is that the specificity in gene action is always a chemical specificity, probably the production of enzymes which guide metabolic processes along particular channels. A given array of genes thus determines the production of a particular kind of protoplasm with particular properties—such, for example, as that of responding to surface forces by the formation of a special sort of semipermeable membrane, and that of responding to trivial asymmetries in the play of external stimuli by polarization, with consequent orderly quantitative gradients in all physiologic processes. Different genes may now be called into play at different points in this simple pattern, either through the local formation of their specific substrates for action, or by activation of a mutational nature. In either case the pattern becomes more complex and qualitatively differentiated. Successive interactions of differentiated regions and the calling into play of additional genes may lead to any degree of complexity of pattern in the organism as a largely self-contained system. The array of genes, assembled in the course of evolution, must of course be one which determines a highly self­regulatory system of reactions. On this view the genes are highly specific chemically, and thus called into play only under very specific conditions; but their morphological effects, if any, rest on quantitative influences of immediate or remote products on growth gradients, which are resultants of all that has gone on before in the organism.
In 'Genetics of Abnormal Growth in the Guinea Pig', Cold Spring Harbor Symposia on Quantitative Biology (1934), 2, 142.
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It was a reaction from the old idea of protoplasm, a name which was a mere repository of ignorance.
In 'The Biochemistry of the Individual' (1937), collected in Neurath Hans (ed.), Perspectives in Biochemistry (1989), 6.
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It was a reaction from the old idea of “protoplasm”, a name which was a mere repository of ignorance.
Perspectives in Biochemistry (1938). As cited in Max Perutz, I Wish I’d Made You Angry Earlier: Essays on Science, Scientists, and Humanity (1998).
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Many of the things that have happened in the laboratory have happened in ways it would have been impossible to foresee, but not impossible to plan for in a sense. I do not think Dr. Whitney deliberately plans his serendipity but he is built that way; he has the art—an instinctive way of preparing himself by his curiosity and by his interest in people and in all kinds of things and in nature, so that the things he learns react on one another and thereby accomplish things that would be impossible to foresee and plan.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 355.
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My position is perfectly definite. Gravitation, motion, heat, light, electricity and chemical action are one and the same object in various forms of manifestation.
Annalen der Chemie und der Pharmacie (1842). Trans. A. S. Eve and C. H. Creasey, The Life and Work of John Tyndall (1945), 94.
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Not every collision,
not every punctilious trajectory
by which billiard-ball complexes
arrive at their calculable meeting places
lead to reaction. ...
Men (and women) are not
as different from molecules
as they think.
Hoffmann, as a chemist-turned-poet is making the analogy of random intermolecular interactions to those of humans. From poem, 'Men and Molecules', The Metamict State (1984), 43. Cited as an epigraph in William L. Masterton and Cecile N. Hurley Chemistry: Principles and Reactions, Updated Edition (2005), 282.
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Not only do the various components of the cells form a living system, in which the capacity to live, react, and reproduce is dependent on the interactions of all the members of the system; but this living system is identical with the genetic system. The form of life is determined not only by the specific nature of the hereditary units but also by the structure and arrangement of the system. The whole system is more than the sum of its parts, and the effect of each of the components depends on and is influenced by all previous reactions, whose sequence is in turn determined by the whole idiotype.
'Cytoplasmic Inheritance in Epilobium and Its Theoretical Significance', Advances in Genetics (1954), 6, 320.
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Perhaps... some day the precision of the data will be brought so far that the mathematician will be able to calculate at his desk the outcome of any chemical combination, in the same way, so to speak, as he calculates the motions of celestial bodies.
Oeuvres (1862), Vol. 2, 550-1. Trans. John Heilbron, Weighing Imponderables and Other Quantitative Science around 1800 (1993), 14.
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Rulers and generals muster their troops. Magnates muster the sums of money which give them power. The fascist dictators muster the irrational human reactions which make it possible for them to attain and maintain their power over the masses. The scientists muster knowledge and means of research. But, thus far, no organization fighting for freedom has ever mustered the biological arsenal where the weapons are to be found for the establishment and the maintenance of human freedom. All precision of our social existence notwithstanding, there is as yet no definition of the word freedom which would be in keeping with natural science. No word is more misused and misunderstood. To define freedom is the same as to define sexual health. But nobody will openly admit this. The advocacy of personal and social freedom is connected with anxiety and guilt feelings. As if to be free were a sin or at least not quite as it should be. Sex-economy makes this guilt feeling comprehensible: freedom without sexual self-determination is in itself a contradiction. But to be sexual means—according to the prevailing human structure—to be sinful or guilty. There are very few people who experience sexual love without guilt feeling. “Free love” has acquired a degrading meaning: it lost the meaning given it by the old fighters for freedom. In films and in books, to be genital and to be criminal are presented as the same thing.
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Since it is proposed to regard chemical reactions as electrical transactions in which reagents act by reason of a constitutional affinity either for electrons or for atomic nuclei, it is important to be able to recognize which type of reactivity any given reagent exhibits.
'Principles of an Electronic Theory of Organic Reactions', Chemical Reviews (1934), 15, 265.
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So many of the chemical reactions occurring in living systems have been shown to be catalytic processes occurring isothermally on the surface of specific proteins, referred to as enzymes, that it seems fairly safe to assume that all are of this nature and that the proteins are the necessary basis for carrying out the processes that we call life.
In 'The Physical Basis of Life', (1951), 39. As given in Andrew Brown, J.D. Bernal: The Sage of Science (2005), 359.
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Suddenly there was an enormous explosion, like a violent volcano. The nuclear reactions had led to overheating in the underground burial grounds. The explosion poured radioactive dust and materials high up into the sky. It was just the wrong weather for such a tragedy. Strong winds blew the radioactive clouds hundreds of miles away. It was difficult to gauge the extent of the disaster immediately, and no evacuation plan was put into operation right away. Many villages and towns were only ordered to evacuate when the symptoms of radiation sickness were already quite apparent. Tens of thousands of people were affected, hundreds dying, though the real figures have never been made public. The large area, where the accident happened, is still considered dangerous and is closed to the public.
'Two Decades of Dissidence', New Scientist (4 Nov 1976), 72, No. 72, 265.
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The blood corpuscles take up the atmospheric oxygen in the lungs, and the vital chemical process accordingly depends essentially on the combination of oxygen absorbed by blood corpuscles with the combustible constituents of the blood to form carbonic acid and water.
Quoted in Joseph Stewart Fruton Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology (1999), 240.
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The chemists who uphold dualism are far from being agreed among themselves; nevertheless, all of them in maintaining their opinion, rely upon the phenomena of chemical reactions. For a long time the uncertainty of this method has been pointed out: it has been shown repeatedly, that the atoms put into movement during a reaction take at that time a new arrangement, and that it is impossible to deduce the old arrangement from the new one. It is as if, in the middle of a game of chess, after the disarrangement of all the pieces, one of the players should wish, from the inspection of the new place occupied by each piece, to determine that which it originally occupied.
Chemical Method (1855), 18.
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The excessive increase of anything causes a reaction in the opposite direction.
The Republic
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The physiological combustion theory takes as its starting point the fundamental principle that the amount of heat that arises from the combustion of a given substance is an invariable quantity–i.e., one independent of the circumstances accompanying the combustion–from which it is more specifically concluded that the chemical effect of the combustible materials undergoes no quantitative change even as a result of the vital process, or that the living organism, with all its mysteries and marvels, is not capable of generating heat out of nothing.
Bemerkungen über das mechanische Aequivalent der Wärme [Remarks on the Mechanical Equivalent of Heat] (1851), 17-9. Trans. Kenneth L. Caneva, Robert Mayer and the Conservation of Energy (1993), 240.
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The question whether atoms exist or not... belongs rather to metaphysics. In chemistry we have only to decide whether the assumption of atoms is an hypothesis adapted to the explanation of chemical phenomena... whether a further development of the atomic hypothesis promises to advance our knowledge of the mechanism of chemical phenomena... I rather expect that we shall some day find, for what we now call atoms, a mathematico-mechanical explanation, which will render an account of atomic weight, of atomicity, and of numerous other properties of the so-called atoms.
Laboratory (1867), 1, 303.
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The reactions follow a pattern, which is valid for the blood of all humans... Basically, in fact, there are four different types of human blood, the so-called blood groups. The number of the groups follows from the fact that the erythrocytes evidently contain substances (iso-agglutinogens) with two different structures, of which both may be absent, or one or both present, in the erythrocytes of a person. This alone would still not explain the reactions; the active substances of the sera, the iso-agglutinins, must also be present in a specific distribution. This is actually the case, since every serum contains those agglutinins which react with the agglutinogens not present in the cells—a remarkable phenomenon, the cause of which is not yet known for certain.
'On Individual Differences in Human Blood', Nobel Lecture (11 Dec 1930). In Nobel Lectures: Physiology or Medicine 1922-1941 (1965), 235.
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Their specific effect on the glucosides might thus be explained by assuming that the intimate contact between the molecules necessary for the release of the chemical reaction is possible only with similar geometrical configurations. To give an illustration I will say that enzyme and glucoside must fit together like lock and key in order to be able to exercise a chemical action on each other. This concept has undoubtedly gained in probability and value for stereochemical research, after the phenomenon itself was transferred from the biological to the purely chemical field. It is an extension of the theory of asymmetry without being a direct consequence of it: for the conviction that the geometrical structure of the molecule even for optical isomers exercises such a great influence on the chemical affinities, in my opinion could only be gained by new actual observations.
'Einfluss der Configuration auf die wirkung der Enzyme', Berichte der deutschen Chemischen Gesellschaft, 1894, 27, 2985-93. Trans. B. Holmstedt and G. Liljestrand (eds.) Readings in Pharmacology (1963), 251.
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There are various causes for the generation of force: a tensed spring, an air current, a falling mass of water, fire burning under a boiler, a metal that dissolves in an acid—one and the same effect can be produced by means of all these various causes. But in the animal body we recognise only one cause as the ultimate cause of all generation of force, and that is the reciprocal interaction exerted on one another by the constituents of the food and the oxygen of the air. The only known and ultimate cause of the vital activity in the animal as well as in the plant is a chemical process.
'Der Lebensprocess im Thiere und die Atmosphare', Annalen der Chemie und Pharmacie (1841), 41, 215-7. Trans. Kenneth L. Caneva, Robert Mo.yer and the Conservation of Energy (1993), 78.
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There is no sharp boundary line separating the reactions of the immune bodies from chemical processes between crystalloids, just as in nature there exists every stage between crystalloid and colloid. The nearer the colloid particle approximates to the normal electrolyte, the nearer its compounds must obviously come to conforming to the law of simple stoichiometric proportions, and the compounds themselves to simple chemical compounds. At this point, it should be recalled that Arrhenius has shown that the quantitative relationship between toxin and antitoxin is very similar to that between acid and base.
Landsteiner and Nicholas von Jagic, 'Uber Reaktionen anorganischer Kolloide und Immunkorper', Münchener medizinischer Wochenschrift (1904), 51, 1185-1189. Trans. Pauline M. H. Mazumdar.
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There is one experiment which I always like to try, because it proves something whichever way it goes. A solution of iodine in water is shaken with bone-black, filtered and tested with starch paste. If the colorless solution does not turn the starch blue, the experiment shows how completely charcoal extracts iodine from aqueous solution. If the starch turns blue, the experiment shows that the solution, though apparently colorless, still contains iodine which can be detected by means of a sensitive starch test.
Applied Colloid Chemistry (1921), 111.
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These results demonstrate that there is a new polymerase inside the virions of RNA tumour viruses. It is not present in supernatents of normal cells but is present in virions of avian sarcoma and leukemia RNA tumour viruses. The polymerase seems to catalyse the incorporation of deoxyrinonucleotide triphosphates into DNA from an RNA template. Work is being performed to characterize further the reaction and the product. If the present results and Baltimore's results with Rauscher leukemia virus are upheld, they will constitute strong evidence that the DNA proviruses have a DNA genome when they are in virions. This result would have strong implications for theories of viral carcinogenesis and, possibly, for theories of information transfer in other biological systems. [Co-author with American virologist Satoshi Mizutani]
'RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus', Nature (1970), 226, 1213.
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This investigation has yielded an unanticipated result that reaction of cyanic acid with ammonia gives urea, a noteworthy result in as much as it provides an example of the artificial production of an organic, indeed a so-called animal, substance from inorganic substances.
[The first report of the epoch-making discovery, that an organic compound can be produced from inorganic substances.]
In 'On the Artificial Formation of Urea'. In J.C. Poggendorff's Annalen der Physik und Chemie (1828), 88, 253. Alternate translation in 'Über Künstliche Bildung des Hamstoffs', Annalen der Physik und Chemie (1828), 12, 253, as translated in Quarterly Journal of Science (Apr-Jun 1828), 25, 491. Collected in Henry Marshall Leicester and Herbert S. Klickstein, A Source Book in Chemistry, 1400-1900 (1951), 310.
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Those of us who were familiar with the state of inorganic chemistry in universities twenty to thirty years ago will recall that at that time it was widely regarded as a dull and uninteresting part of the undergraduate course. Usually, it was taught almost entirely in the early years of the course and then chiefly as a collection of largely unconnected facts. On the whole, students concluded that, apart from some relationships dependent upon the Periodic table, there was no system in inorganic chemistry comparable with that to be found in organic chemistry, and none of the rigour and logic which characterised physical chemistry. It was widely believed that the opportunities for research in inorganic chemistry were few, and that in any case the problems were dull and uninspiring; as a result, relatively few people specialized in the subject... So long as inorganic chemistry is regarded as, in years gone by, as consisting simply of the preparations and analysis of elements and compounds, its lack of appeal is only to be expected. The stage is now past and for the purpose of our discussion we shall define inorganic chemistry today as the integrated study of the formation, composition, structure and reactions of the chemical elements and compounds, excepting most of those of carbon.
Inaugural Lecture delivered at University College, London (1 Mar 1956). In The Renaissance of Inorganic Chemistry (1956), 4-5.
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To any action there is always an opposite and equal reaction; in other words, the actions of two bodies upon each other are always equal and always opposite in direction.
The Principia: Mathematical Principles of Natural Philosophy (1687), 3rd edition (1726), trans. I. Bernard Cohen and Anne Whitman (1999), Axioms, or Laws of Motion, Law 3, 417.
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To solve a problem is to create new problems, new knowledge immediately reveals new areas of ignorance, and the need for new experiments. At least, in the field of fast reactions, the experiments do not take very long to perform.
From Nobel Lecture (11 Dec 1967), 'Flash Photolysis and Some of its Applications.' In Nobel Lectures: Chemistry 1963-1970 (1972), 261.
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Truth and falsity, indeed understanding, is not necessarily something purely intellectual, remote from feelings and attitudes. ... It is in the total conduct of men rather than in their statements that truth or falsehood lives, more in what a man does, in his real reaction to other men and to things, in his will to do them justice, to live at one with them. Here lies the inner connection between truth and justice. In the realm of behavior and action, the problem recurs as to the difference between piece and part.
From 'On Truth', collected in Mary Henle (ed.), Documents of Gestalt Psychology (1961), 28.
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We are just beginning to understand how molecular reaction systems have found a way to “organize themselves”. We know that processes of this nature ultimately led to the life cycle, and that (for the time being?) Man with his central nervous system, i.e. his memory, his mind, and his soul, stands at the end of this development and feels compelled to understand this development. For this purpose he must penetrate into the smallest units of time and space, which also requires new ideas to make these familiar concepts from physics of service in understanding what has, right into our century, appeared to be beyond the confines of space and time.
Answering “Where Now?” as the conclusion of his Nobel Lecture (11 Dec 1967) on 'Immeasurably Fast Reactions', published in Nobel Lectures, Chemistry 1963-1970 (1972).
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We may regard [Scheele] not only as having given the first indication of the rich harvest to be reaped by the investigation of the compounds of organic chemistry, but as having been the first to discover and make use of characteristic reactions by which closely allied substances can be detected and separated, so that he must be considered one of the chief founders of analytical chemistry.
In Treatise on Chemistry (1877, 1890), Vol. 1, 23.
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What is terrorism? Terrorism in some sense is a reaction against the creation of a type one [planet-wide advanced] civilization. Now most terrorists cannot articulate this. … What they’re reacting to is not modernism. What they’re reacting to is the fact that we’re headed toward a multicultural tolerant scientific society and that is what they don’t want. They don’t want science. They want a theocracy. They don’t want multiculturalism. They want monoculturalism. So instinctively they don’t like the march toward a type one civilization. Now which tendency will win? I don’t know, but I hope that we emerge as a type one civilization.
From transcript of online video interview (29 Sep 2010) with Paul Hoffman, 'What is the likelihood that mankind will destroy itself?', on bigthink.com website.
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With the nervous system intact the reactions of the various parts of that system, the 'simple reflexes', are ever combined into great unitary harmonies, actions which in their sequence one upon another constitute in their continuity what may be termed the 'behaviour'.
The Integrative Action of the Nervous System (1906), 237.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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- 90 -
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- 80 -
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- 70 -
Samuel Morse
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- 60 -
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- 50 -
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- 40 -
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- 30 -
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- 20 -
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- 10 -
John Watson
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