...I may perhaps venture a short word on the question much discussed in certain quarters, whether in the work of excavation it is a good thing to have cooperation between men and women ... Of a mixed dig ... I have seen something, and it is an experiment that I would be reluctant to try again. I would grant if need be that women are admirable fitted for the work, yet I would uphold that they should undertake it by themselves ... the work of an excavator on the dig and off it lays on those who share it a bond of closer daily intercourse than is conceivable ... between men and women, except in chance cases, I do not believe that such close and unavoidable companionship can ever be other than a source of irritation; at any rate, I believe that however it may affect women, the ordinary male at least cannot stand it ... A minor ... objection lies in one particular form of contraint ... moments will occur on the best regulated dig when you want to say just what you think without translation, which before the ladies, whatever their feelings about it, cannot be done.

[The chemical bond] First, it is related to the disposition of two electrons (remember, no one has ever seen an electron!): next, these electrons have their spins pointing in opposite directions (remember, no one can ever measure the spin of a particular electron!): then, the spatial distribution of these electrons is described analytically with some degree of precision (remember, there is no way of distinguishing experimentally the density distribution of one electron from another!): concepts like hybridization, covalent and ionic structures, resonance, all appear, not one of which corresponds to anything that is directly measurable. These concepts make a chemical bond seem so real, so life-like, that I can almost see it. Then I wake with a shock to the realization that a chemical bond does not exist; it is a figment of the imagination that we have invented, and no more real than the square root of - 1. I will not say that the known is explained in terms of the unknown, for that is to misconstrue the sense of intellectual adventure. There is no explanation: there is form: there is structure: there is symmetry: there is growth: and there is therefore change and life.

The Mighty Task is Done

At last the mighty task is done;
Resplendent in the western sun
The Bridge looms mountain high;
Its titan piers grip ocean floor,
Its great steel arms link shore with shore,
Its towers pierce the sky.

On its broad decks in rightful pride,
The world in swift parade shall ride,
Throughout all time to be;
Beneath, fleet ships from every port,
Vast landlocked bay, historic fort,
And dwarfing all the sea.

To north, the Redwood Empires gates;
To south, a happy playground waits,
In Rapturous appeal;
Here nature, free since time began,
Yields to the restless moods of man,
Accepts his bonds of steel.

Launched midst a thousand hopes and fears,
Damned by a thousand hostile sneers,
Yet Neer its course was stayed,
But ask of those who met the foe
Who stood alone when faith was low,
Ask them the price they paid.

Ask of the steel, each strut and wire,
Ask of the searching, purging fire,
That marked their natal hour;
Ask of the mind, the hand, the heart,
Ask of each single, stalwart part,
What gave it force and power.

An Honored cause and nobly fought
And that which they so bravely wrought,
Now glorifies their deed,
No selfish urge shall stain its life,
Nor envy, greed, intrigue, nor strife,
Nor false, ignoble creed.

High overhead its lights shall gleam,
Far, far below lifes restless stream,
Unceasingly shall flow;
For this was spun its lithe fine form,
To fear not war, nor time, nor storm,
For Fate had meant it so.

A great ball of fire about a mile in diameter, changing colors as it kept shooting upward, from deep purple to orange, expanding, growing bigger, rising as it was expanding, an elemental force freed from its bonds after being chained for billions of years.
On the first atomic explosion in New Mexico, 16 Jul 1945.

Alcmaeon maintains that the bond of health is the 'equal balance' of the powers, moist and dry, cold and hot, bitter and sweet, and the rest, while the 'supremacy' of one of them is the cause of disease; for the supremacy of either is destructive. Illness comes aboutdirectly through excess of heat or cold, indirectly through surfeit or deficiency of nourishment; and its centre is either the blood or the marrow or the brain. It sometimes arises in these centres from external causes, moisture of some sort or environment or exhaustion or hardship or similar causes. Health on the other hand is the proportionate admixture of the qualities.

All Nature is linked together by invisible bonds and every organic creature, however low, however feeble, however dependent, is necessary to the well-being of some other among the myriad forms of life.

All power, all subordination rests on the executioner: he is the horror and the bond of human association. Remove this incomprehensible agent from the world, and the very moment order gives way to chaos, thrones topple, and society disappears

Aristotle... a mere bond-servant to his logic, thereby rendering it contentious and well nigh useless.

At quite uncertain times and places,
The atoms left their heavenly path,
And by fortuitous embraces,
Engendered all that being hath.
And though they seem to cling together,
And form 'associations' here,
Yet, soon or late, they burst their tether,
And through the depths of space career.

Carbon is, as may easily be shown and as I shall explain in greater detail later, tetrabasic or tetratomic, that is 1 atom of carbon = C = 12 is equivalent to 4 At.H. The simplest connection of C with an element of the first Group, with H or Cl for example, is therefore: CH₄ and CCl₄.

Conclusion: Big helix in several chains, phosphates on outside, phosphate-phosphate inter-helical bonds disrupted by water. Phosphate links available to proteins.

For Christmas, 1939, a girl friend gave me a book token which I used to buy Linus Pauling's recently published Nature of the Chemical Bond. His book transformed the chemical flatland of my earlier textbooks into a world of three-dimensional structures.

Hence, a devout Christian must avoid astrologers and all impious soothsayers, especially when they tell the truth, for fear of leading his soul into error by consorting with demons and entangling himself with the bonds of such association.

Hypotheses may be useful, though involving much that is superfluous, and even erroneous: for they may supply the true bond of connexion of the facts; and the superfluity and error may afterwards be pared away.

I cannot let the year run out without sending you a sign of my continued existence and to extend my sincere wishes for the well-being of you and your dear ones in the New Year. We will not be able to send New Year greetings much longer; but even when we have passed away and have long since decomposed, the bonds that united us in life will remain and we shall be remembered as a not too common example of two men, who truly without envy and jealousy, contended and struggled in the same field, yet nevertheless remained always closely bound in friendship.

I have slipped the bonds of Earth to dance with dolphins.

In an age of egoism, it is so difficult to persuade man that of all studies, the most important is that of himself. This is because egoism, like all passions, is blind. The attention of the egoist is directed to the immediate needs of which his senses give notice, and cannot be raised to those reflective needs that reason discloses to us; his aim is satisfaction, not perfection. He considers only his individual self; his species is nothing to him. Perhaps he fears that in penetrating the mysteries of his being he will ensure his own abasement, blush at his discoveries, and meet his conscience. True philosophy, always at one with moral science, tells a different tale. The source of useful illumination, we are told, is that of lasting content, is in ourselves. Our insight depends above all on the state of our faculties; but how can we bring our faculties to perfection if we do not know their nature and their laws! The elements of happiness are the moral sentiments; but how can we develop these sentiments without considering the principle of our affections, and the means of directing them? We become better by studying ourselves; the man who thoroughly knows himself is the wise man. Such reflection on the nature of his being brings a man to a better awareness of all the bonds that unite us to our fellows, to the re-discovery at the inner root of his existence of that identity of common life actuating us all, to feeling the full force of that fine maxim of the ancients: 'I am a man, and nothing human is alien to me.'

Into whatsoever houses I enter, I will enter to help the sick, and I will abstain from all intentional wrong-doing and harm, especially from abusing the bodies of man or woman, bond or free. And whatsoever I shall see or hear in the course of my profession, as well as outside my profession in my intercourse with men, if it be what should not be published abroad, I will never divulge, holding such things to be holy secrets.

It has been recognized that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as the methods of structural chemistry are further applied to physiological problems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature.

It is possible with … carbon … to form very large molecules that are stable. This results from the stability of the carbon-to-carbon bond. You must have complexity in order to achieve the versatility characteristic of living organisms. You can achieve this complexity with carbon forming the molecular backbone.

It is structure that we look for whenever we try to understand anything. All science is built upon this search; we investigate how the cell is built of reticular material, cytoplasm, chromosomes; how crystals aggregate; how atoms are fastened together; how electrons constitute a chemical bond between atoms. We like to understand, and to explain, observed facts in terms of structure. A chemist who understands why a diamond has certain properties, or why nylon or hemoglobin have other properties, because of the different ways their atoms are arranged, may ask questions that a geologist would not think of formulating, unless he had been similarly trained in this way of thinking about the world.

It was obvious—to me at any rate—that the answer was to why an enzyme is able to speed up a chemical reaction by as much as 10 million times. It had to do this by lowering the energy of activation—the energy of forming the activated complex. It could do this by forming strong bonds with the activated complex, but only weak bonds with the reactants or products.

Measured objectively, what a man can wrest from Truth by passionate striving is utterly infinitesimal. But the striving frees us from the bonds of the self and makes us comrades of those who are the best and the greatest.

Oh, I have slipped the surly bonds of earth
and danced the skies on laughter-silvered wings;
Sunward I’ve climbed, and joined the tumbling mirth
of sun-split clouds and done a hundred things
you have not dreamed of wheeled and soared and swung
high in the sunlit silence. Hovering there,
I’ve chased the shouting wind along, and flung
my eager craft through footless halls of air.
Up, up the long, delirious, burning blue
I’ve topped the windswept heights with easy grace
where never lark, or even eagle flew
and, while with silent, lifting mind I’ve trod
the high untrespassed sanctity of space,
put out my hand, and touched the face of God.

One always finds among men who are reputed to be reasonable some evidence of this tendency to inquire into the reason of things; of this desire to know not simply how things are, but why they are one way rather than another; and, consequently, of this awareness of a relation which is not gained through the senses, this notion of an abstract bond by virtue of which one thing is subordinated to another which determines and explains it.

One is almost tempted to say... at last I can almost see a bond. But that will never be, for a bond does not really exist at all: it is a most convenient fiction which, as we have seen, is convenient both to experimental and theoretical chemists.

Our conception of a native protein molecule (showing specific properties) is the following. The molecule consists of one polypeptide chain which continues without interruption throughout the molecule (or, in certain cases, of two or more such chains); this chain is folded into a uniquely defined configuration, in which it is held by hydrogen bonds between the peptide nitrogen and oxygen atoms and also between the free amino and carboxyl groups of the diamino and dicarboxyl amino acid residues.
The characteristic specific properties of native proteins we attribute to their uniquely defined configurations.
The denatured protein molecule we consider to be characterized by the absence of a uniquely defined configuration.
[Co-author with American chemist, Linus Pauling (1901-94)]

Perhaps the strongest bond of sympathy between mathematics and poetry, however, is the endless invention of each. Dr. Johnson remarked, “The essence of poetry is invention; such invention as, by producing something unexpected, surprises and delights”; but he might have said the same of mathematics.

Quietly, like a night bird, floating, soaring, wingless.
We glide from shore to shore, curving and falling
but not quite touching;
Earth: a distant memory seen in an instant of repose,
crescent shaped, ethereal, beautiful,
I wonder which part is home, but I know it doesn’t matter . . .
the bond is there in my mind and memory;
Earth: a small, bubbly balloon hanging delicately
in the nothingness of space.

Saying that each of two atoms can attain closed electron shells by sharing a pair of electrons is equivalent to saying that husband and wife, by having a total of two dollars in a joint account and each having six dollars in individual bank accounts, have eight dollars apiece!

Sometimes my courage fails me and I think I ought to stop working, live in the country and devote myself to gardening. But I am held by a thousand bonds, and I don't know when I shall be able to arrange things otherwise. Nor do I know whether, even by writing scientific books, I could live without the laboratory.

The energy of a covalent bond is largely the energy of resonance of two electrons between two atoms. The examination of the form of the resonance integral shows that the resonance energy increases in magnitude with increase in the overlapping of the two atomic orbitals involved in the formation of the bond, the word ‘overlapping” signifying the extent to which regions in space in which the two orbital wave functions have large values coincide... Consequently it is expected that of two orbitals in an atom the one which can overlap more with an orbital of another atom will form the stronger bond with that atom, and, moreover, the bond formed by a given orbital will tend to lie in that direction in which the orbital is concentrated.

The good Christian should beware of mathematicians, and all those who make empty prophecies. The danger already exists that the mathematicians have made a covenant with the devil to darken the spirit and to confine man in the bonds of Hell.

The novel feature of the structure is the manner in which the two chains are held together by the purine and pyrimidine bases. The planes of the bases are perpendicular to the fibre axis. They are joined together in pairs, a single base from one chain being hydrogen-bonded to a single base from the other chain, so that the two lie side by side with identical z-co-ordinates. One of the pair must be 11 purine and the other a pyrimidine for bonding to occur. The hydrogen bonds are made as follows: purine position I to pyrimidine position I; purine position 6 to pyrimidine position 6.
[Co-author with Francis Crick]

The question now at issue, whether the living species are connected with the extinct by a common bond of descent, will best be cleared up by devoting ourselves to the study of the actual state of the living world, and to those monuments of the past in which the relics of the animate creation of former ages are best preserved and least mutilated by the hand of time.

The rallying motto of a sectarian name is incapable of exciting to sober, calm, scientific investigation; it only rouses the explosive spirit of accusations of heresy to a fierce volcanic flame. Truth and the weal of humanity should be the only motto of the genuine elucidators of the art, and the watchword of their brotherly, peaceful bond of union, without slavish adherence to any sectarian leader, if we would not see the little good that we know completely sacrificed to party spirit and discord.

The separate atoms of a molecule are not connected all with all, or all with one, but, on the contrary, each one is connected only with one or with a few neighbouring atoms, just as in a chain link is connected with link.

There must be some bond of union between mass and the chemical elements; and as the mass of a substance is ultimately expressed (although not absolutely, but only relatively) in the atom, a functional dependence should exist and be discoverable between the individual properties of the elements and their atomic weights. But nothing, from mushrooms to a scientific dependence can be discovered without looking and trying. So I began to look about and write down the elements with their atomic weights and typical properties, analogous elements and like atomic weights on separate cards, and soon this convinced me that the properties of the elements are in periodic dependence upon their atomic weights; and although I had my doubts about some obscure points, yet I have never doubted the universality of this law, because it could not possibly be the result of chance.

There's nothing situate under heaven's eye
But hath his bond in earth, in sea, in sky.
The beasts, the fishes, and the winged fowls
Are their males' subjects and at their controls.
Man, more divine, the master of all these,
Lord of the wide world and wild wat'ry seas,
Indu'd with intellectual sense and souls,
Of more pre-eminence than fish and fowls,
Are masters to their females, and their lords;
Then let your will attend on their accords.

This, as you know, is my opinion, that as the body when it tyrannizes over the mind ruins and destroys all its soundness, so in the same way when the mind becomes the tyrant, and not merely the true lord, it wastes and destroys the soundness of the body first, and then their common bond of union … and sins against prudence and charity.

Twenty years ago many chemists would have defended the theory of bond arms as a satisfactory explanation because they had become accustomed to thinking of it as unique and as ultimate.

We find that one of the most rewarding features of being scientists these days ... is the common bond which the search for truth provides to scholars of many tongues and many heritages. In the long run, that spirit will inevitably have a constructive effect on the benefits which man can derive from knowledge of himself and his environment.

We need to explore the possibility that homosexual bonding may be a biological mechanism.

When carbon (C), Oxygen (o) and hydrogen (H) atoms bond in a certain way to form sugar, the resulting compound has a sweet taste. The sweetness resides neither in the C, nor in the O, nor in the H; it resides in the pattern that emerges from their interaction. It is an emergent property. Moreover, strictly speaking, is not a property of the chemical bonds. It is a sensory experience that arises when the sugar molecules interact with the chemistry of our taste buds, which in turns causes a set of neurons to fire in a certain way. The experience of sweetness emerges from that neural activity.

When the simplest compounds of this element are considered (marsh gas, chloride of carbon, chloroform, carbonic acid, phosgene, sulphide of carbon, hydrocyanic acid, etc.) it is seen that the quantity of carbon which chemists have recognised as the smallest possible, that is, as an atom, always unites with 4 atoms of a monatomic or with two atoms of a diatomic element; that in general, the sum of the chemical units of the elements united with one atom of carbon is 4. This leads us to the view that carbon is tetratomic or tetrabasic. In the cases of substances which contain several atoms of carbon, it must be assumed that at least some of the atoms are in some way held in the compound by the affinity of carbon, and that the carbon atoms attach themselves to one another, whereby a part of the affinity of the one is naturally engaged with an equal part of the affinity of the other. The simplest and therefore the most probable case of such an association of carbon atoms is that in which one affinity unit of one is bound by one of the other. Of the 2 x 4 affinity units of the two carbon atoms, two are used up in holding the atoms together, and six remain over, which can be bound by atom)' of other elements.

Yet I also appreciate that we cannot win this battle to save species and environments without forging an emotional bond between ourselves and nature as well–for we will not fight to save what we do not love (but only appreciate in some abstract sense). So let them all continue–the films, the books, the television programs, the zoos, the little half acre of ecological preserve in any community, the primary school lessons, the museum demonstrations, even ... the 6:00 A.M. bird walks. Let them continue and expand because we must have visceral contact in order to love. We really must make room for nature in our hearts.