Pair Quotes (10 quotes)
A single axis is harmless, but a murderous mathematician can go on a killing spree with a pair of axes.
Chemists show us that strange property, catalysis, which enables a substance while unaffected itself to incite to union elements around it. So a host, or hostess, who may know but little of those concerned, may, as a social switchboard, bring together the halves of pairs of scissors, men who become life-long friends, men and women who marry and are happy husbands and wives.
I may finally call attention to the probability that the association of paternal and maternal chromosomes in pairs and their subsequent separation during the reducing division as indicated above may constitute the physical basis of the Mendelian law of heredity.
I strongly reject any conceptual scheme that places our options on a line, and holds that the only alternative to a pair of extreme positions lies somewhere between them. More fruitful perspectives often require that we step off the line to a site outside the dichotomy.
I wasn’t aware of Chargaff’s rules when he said them, but the effect on me was quite electric because I realized immediately that if you had this sort of scheme that John Griffith was proposing, of adenine being paired with thymine, and guanine being paired with cytosine, then you should get Chargaff’s rules.
I was very excited, but I didn’t actually tell Chargaff because it was something I was doing with John Griffith. There was a sort of musical comedy effect where I forgot what the bases were and I had to go to the library to check, and I went back to John Griffith to find out which places he said. Low and behold, it turned out that John Griffith’s ideas fitted in with Chargaff’s rules!
This was very exciting, and we thought “ah ha!” and we realized—I mean what anyone who is familiar with the history of science ought to realize—that when you have one-to-one ratios, it means things go to together. And how on Earth no one pointed out this simple fact in those years, I don’t know.
I was very excited, but I didn’t actually tell Chargaff because it was something I was doing with John Griffith. There was a sort of musical comedy effect where I forgot what the bases were and I had to go to the library to check, and I went back to John Griffith to find out which places he said. Low and behold, it turned out that John Griffith’s ideas fitted in with Chargaff’s rules!
This was very exciting, and we thought “ah ha!” and we realized—I mean what anyone who is familiar with the history of science ought to realize—that when you have one-to-one ratios, it means things go to together. And how on Earth no one pointed out this simple fact in those years, I don’t know.
If the actual order of the bases on one of the pair of chains were given, one could write down the exact order of the bases on the other one, because of the specific pairing. Thus one chain is, as it were, the complement of the other, and it is this feature which suggests how the deoxyribonucleic acid molecule might duplicate itself.
[Co-author with Francis Crick]
[Co-author with Francis Crick]
The Earth has recovered after fevers like this, and there are no grounds for thinking that what we are doing will destroy Gaia, but if we continue business as usual, our species may never again enjoy the lush and verdant world we had only a hundred years ago. What is most in danger is civilization; humans are tough enough for breeding pairs to survive, and Gaia is toughest of all. What we are doing weakens her but is unlikely to destroy her. She has survived numerous catastrophes in her three billion years or more of life.
The novel feature of the structure is the manner in which the two chains are held together by the purine and pyrimidine bases. The planes of the bases are perpendicular to the fibre axis. They are joined together in pairs, a single base from one chain being hydrogen-bonded to a single base from the other chain, so that the two lie side by side with identical z-co-ordinates. One of the pair must be 11 purine and the other a pyrimidine for bonding to occur. The hydrogen bonds are made as follows: purine position I to pyrimidine position I; purine position 6 to pyrimidine position 6.
[Co-author with Francis Crick]
[Co-author with Francis Crick]
The smallest particles of matter were said [by Plato] to be right-angled triangles which, after combining in pairs, ... joined together into the regular bodies of solid geometry; cubes, tetrahedrons, octahedrons and icosahedrons. These four bodies were said to be the building blocks of the four elements, earth, fire, air and water ... [The] whole thing seemed to be wild speculation. ... Even so, I was enthralled by the idea that the smallest particles of matter must reduce to some mathematical form ... The most important result of it all, perhaps, was the conviction that, in order to interpret the material world we need to know something about its smallest parts.
[Recalling how as a teenager at school, he found Plato's Timaeus to be a memorable poetic and beautiful view of atoms.]
[Recalling how as a teenager at school, he found Plato's Timaeus to be a memorable poetic and beautiful view of atoms.]
To describe all the several pairs of the spinal Nerves, and to rehearse all their branchings, and to unfold the uses and actions of them, would be a work of an immense labour and trouble: and as this Neurologie cannot be learned nor understood without an exact knowledge of the Muscles, we may justly here forbear entring upon its particular institution.