[The octopus has] an amazing skin, because there are up to 20 million of these chromatophore pigment cells and to control 20 million of anything is going to take a lot of processing power. ... These animals have extraordinarily large, complicated brains to make all this work. ... And what does this mean about the universe and other intelligent life? The building blocks are potentially there and complexity will arise. Evolution is the force that's pushing that. I would expect, personally, a lot of diversity and a lot of complicated structures. It may not look like us, but my personal view is that there is intelligent life out there.

Quantum theory thus reveals a basic oneness of the universe. It shows that we cannot decompose the world into independently existing smallest units. As we penetrate into matter, nature does not show us any isolated “building blocks,” but rather appears as a complicated web of relations between the various parts of the whole. These relations always include the observer in an essential way. The human observer constitute the final link in the chain of observational processes, and the properties of any atomic object can be understood only in terms of the object’s interaction with the observer.

Some scientists claim that hydrogen because it is so plentiful is the basic building block of the universe. I dispute that. I say that there is more stupidity than hydrogen and that is the basic building block of the universe.

The ability of the genes to vary and, when they vary (mutate), to reproduce themselves in their new form, confers on these cell elements, as Muller has so convincingly pointed out, the properties of the building blocks required by the process of evolution. Thus, the cell, robbed of its noblest prerogative, was no longer the ultimate unit of life. This title was now conferred on the genes, subcellular elements, of which the cell nucleus contained many thousands and, more precisely, like Noah’s ark, two of each kind.

The essential molecule of reproduction, DNA, … is composed of only four nitrogen bases (adenine, thymine, guanine, and cytosine), the sugar deoxyribose, and a phosphate. DNA’s intermediary, RNA, differs only by the substitution of the sugar ribose for deoxyribose and the nitrogen base uracil for thymine. The proteins of living organisms are made with a mere 20 amino acids, all arranged in a “left-handed” configuration. Taking into account all 28 building blocks, or “letters” (20 amino acids, five bases, two sugars, and one phosphate), the message is clear: With such a limited alphabet, all life must have had a common chemical origin.

The language of the genes has a simple alphabet, not with twenty-six letters, but just four. These are the four different DNA bases—adenine, guanine, cytosine and thymine (A, G, C and T for short). The bases are arranged in words of three letters such as CGA or TGG. Most of the words code for different amino acids, which themselves are joined together to make proteins, the building blocks of the body.

The most fundamental difference between compounds of low molecular weight and macromolecular compounds resides in the fact that the latter may exhibit properties that cannot be deduced from a close examination of the low molecular weight materials. Not very different structures can be obtained from a few building blocks; but if 10,000 or 100,000 blocks are at hand, the most varied structures become possible, such as houses or halls, whose special structure cannot be predicted from the constructions that are possible with only a few building blocks... Thus, a chromosome can be viewed as a material whose macromolecules possess a well defined arrangement, like a living room in which each piece of furniture has its place and not, as in a warehouse, where the pieces of furniture are placed together in a heap without design.

The smallest particles of matter were said [by Plato] to be right-angled triangles which, after combining in pairs, ... joined together into the regular bodies of solid geometry; cubes, tetrahedrons, octahedrons and icosahedrons. These four bodies were said to be the building blocks of the four elements, earth, fire, air and water ... [The] whole thing seemed to be wild speculation. ... Even so, I was enthralled by the idea that the smallest particles of matter must reduce to some mathematical form ... The most important result of it all, perhaps, was the conviction that, in order to interpret the material world we need to know something about its smallest parts.
[Recalling how as a teenager at school, he found Plato's Timaeus to be a memorable poetic and beautiful view of atoms.]

They think that differential equations are not reality. Hearing some colleagues speak, it’s as though theoretical physics was just playing house with plastic building blocks. This absurd idea has gained currency, and now people seem to feel that theoretical physicists are little more than dreamers locked away ivory towers. They think our games, our little houses, bear no relation to their everyday worries, their interests, their problems, or their welfare. But I’m going to tell you something, and I want you to take it as a ground rule for this course. From now on I will be filling this board with equations. … And when I'm done, I want you to do the following: look at those numbers, all those little numbers and Greek letters on the board, and repeat to yourselves, “This is reality,” repeat it over and over.