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Who said: “I was going to record talking... the foil was put on; I then shouted 'Mary had a little lamb',... and the machine reproduced it perfectly.”
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Home > Category Index for Science Quotations > Category Index C > Category: Compound

Compound Quotes (113 quotes)

“The Universe repeats itself, with the possible exception of history.” Of all earthly studies history is the only one that does not repeat itself. ... Astronomy repeats itself; botany repeats itself; trigonometry repeats itself; mechanics repeats itself; compound long division repeats itself. Every sum if worked out in the same way at any time will bring out the same answer. ... A great many moderns say that history is a science; if so it occupies a solitary and splendid elevation among the sciences; it is the only science the conclusions of which are always wrong.
In 'A Much Repeated Repetition', Daily News (26 Mar 1904). Collected in G. K. Chesterton and Dale Ahlquist (ed.), In Defense of Sanity: The Best Essays of G.K. Chesterton (2011), 82.
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... every chemical combination is wholly and solely dependent on two opposing forces, positive and negative electricity, and every chemical compound must be composed of two parts combined by the agency of their electrochemical reaction, since there is no third force. Hence it follows that every compound body, whatever the number of its constituents, can be divided into two parts, one of which is positively and the other negatively electrical.
Essai sur la théorie des proportions chemiques (1819), 98. Quoted by Henry M. Leicester in article on Bessel in Charles Coulston Gillespie (editor), Dictionary of Scientific Biography (1981), Vol. 2, 94.
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Compounds formed by chemical attraction, possess new properties different from those of their component parts... chemists have long believed that the contrary took place in their combination. They thought, in fact, that the compounds possessed properties intermediate between those of their component parts; so that two bodies, very coloured, very sapid, or insapid, soluble or insoluble, fusible or infusible, fixed or volatile, assumed in chemical combination, a shade or colour, or taste, solubility or volatility, intermediate between, and in some sort composed of, the same properties which were considered in their principles. This is an illusion or error which modern chemistry is highly interested to overthrow.
Quoted in A General System of Chemical Knowledge (1804), Vol. I, trans. W. Nicholson, 102-3.
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Dass die bis jetzt unzerlegten chemischen Elemente absolut unzerlegbare Stoffe seien, ist gegenwärtig mindestens sehr unwahrscheinlich. Vielmehr scheint es, dass die Atome der Elemente nicht die letzten, sondern nur die näheren Bestandtheile der Molekeln sowohl der Elemente wie der Verbindungen bilden, die Molekeln oder Molecule als Massentheile erster, die Atome als solche zweiter Ordnung anzusehen sind, die ihrerseits wiederum aus Massentheilchen einer dritten höheren Ordnung bestehen werden.
That the as yet undivided chemical elements are absolutely irreducible substances, is currently at least very unlikely. Rather it seems, that the atoms of elements are not the final, but only the immediate constituents of the molecules of both the elements and the compounds—the Molekeln or molecule as foremost division of matter, the atoms being considered as second order, in turn consisting of matter particles of a third higher order.
[Speculating in 1870, on the existence of subatomic particles, in opening remark of the paper by which he became established as co-discoverer of the Periodic Law.]
'Die Natur der chemischen Elemente als Function ihrer Atomgewichte' ('The Nature of the Chemical Elements as a Function of their Atomic Weight'), Annalen der Chemie (1870), supp. b, 354. Original German paper reprinted in Lothar Meyer and Dmitry Ivanovich Mendeleyev, Das natürliche System der chemischen Elemente: Abhandlungen (1895), 9. Translation by Webmaster, with punctuation faithful to the original, except a comma was changed to a dash to improve readability.
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If the Indians hadn’t spent the $24. In 1626 Peter Minuit, first governor of New Netherland, purchased Manhattan Island from the Indians for about $24. … Assume for simplicity a uniform rate of 7% from 1626 to the present, and suppose that the Indians had put their $24 at [compound] interest at that rate …. What would be the amount now, after 280 years? 24 x (1.07)280 = more than 4,042,000,000.
The latest tax assessment available at the time of writing gives the realty for the borough of Manhattan as $3,820,754,181. This is estimated to be 78% of the actual value, making the actual value a little more than $4,898,400,000.
The amount of the Indians’ money would therefore be more than the present assessed valuation but less than the actual valuation.
In A Scrap-book of Elementary Mathematics: Notes, Recreations, Essays (1908), 47-48.
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A chemical compound once formed would persist for ever, if no alteration took place in surrounding conditions. But to the student of Life the aspect of nature is reversed. Here, incessant, and, so far as we know, spontaneous change is the rule, rest the exception—the anomaly to be accounted for. Living things have no inertia and tend to no equilibrium.
From Address (22 Jul 1854) delivered at St. Martin’s Hall, published as a pamphlet (1854), 7, and collected in 'Educational Value of Natural History Sciences', Lay Sermons, Addresses, and Reviews (1870), 75.
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A chemical name should not be a phrase, it ought not to require circumlocutions to become definite; it should not be of the type “Glauber’s salt”, which conveys nothing about the composition of the substance; it should recall the constituents of a compound; it should be non-committal if nothing is known about the substance; the names should preferably be coined from Latin or Greek, so that their meaning can be more widely and easily understood; the form of the words should be such that they fit easily into the language into which they are to be incorporated.
(1782) As quoted in Archibald Clow, Chemical Revolution: A Contribution to Social Technology (1952, 1992), 618.
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A marveilous newtrality have these things mathematicall, and also a strange participation between things supernaturall, immortall, intellectuall, simple and indivisible, and things naturall, mortall, sensible, componded and divisible.
John Dee
In Mathematicall Praeface to the Elements of Geometrie of Euclid of Megara (1570).
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A schism has taken place among the chemists. A particular set of them in France have undertaken to remodel all the terms of the science, and to give every substance a new name, the composition, and especially the termination of which, shall define the relation in which it stands to other substances of the same family, But the science seems too much in its infancy as yet, for this reformation; because in fact, the reformation of this year must be reformed again the next year, and so on, changing the names of substances as often as new experiments develop properties in them undiscovered before. The new nomenclature has, accordingly, been already proved to need numerous and important reformations. ... It is espoused by the minority here, and by the very few, indeed, of the foreign chemists. It is particularly rejected in England.
Letter to Dr. Willard (Paris, 1788). In Thomas Jefferson and John P. Foley (ed.), The Jeffersonian Cyclopedia (1900), 135. From H.A. Washington, The Writings of Thomas Jefferson (1853-54). Vol 3, 15.
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A very interesting set of compounds that were waiting for the right disease.
[Commenting on AZT and similar drugs he had synthesized.]
Quoted in 'Jerome Horwitz, AZT Creator, Dies at 93', New York Times (21 Sep 2012).
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A working definition of life … could thing in terms of a large molecule made up of carbon compounds that can replicate, or make copies of itself, and metabolize food and energy…: macromolecule, metabolism, replication.
From interview, 'The Seeds of Life', in The Omni Interviews (1984), 4.
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About eight days ago I discovered that sulfur in burning, far from losing weight, on the contrary, gains it; it is the same with phosphorus; this increase of weight arises from a prodigious quantity of air that is fixed during combustion and combines with the vapors. This discovery, which I have established by experiments, that I regard as decisive, has led me to think that what is observed in the combustion of sulfur and phosphorus may well take place in the case of all substances that gain in weight by combustion and calcination; and I am persuaded that the increase in weight of metallic calxes is due to the same cause... This discovery seems to me one of the most interesting that has been made since Stahl and since it is difficult not to disclose something inadvertently in conversation with friends that could lead to the truth I have thought it necessary to make the present deposit to the Secretary of the Academy to await the time I make my experiments public.
Sealed note deposited with the Secretary of the French Academy 1 Nov 1772. Oeuvres de Lavoisier, Correspondance, Fasc. II. 1770-75 (1957), 389-90. Adapted from translation by A. N. Meldrum, The Eighteenth-Century Revolution in Science (1930), 3.
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All the experiments which have been hitherto carried out, and those that are still being daily performed, concur in proving that between different bodies, whether principles or compounds, there is an agreement, relation, affinity or attraction (if you will have it so), which disposes certain bodies to unite with one another, while with others they are unable to contract any union: it is this effect, whatever be its cause, which will help us to give a reason for all the phenomena furnished by chemistry, and to tie them together.
From Elemens de Chymie Theorique (1749). As quoted, in Trevor Harvey Levere, Affinity and Matter: Elements of Chemical Philosophy, 1800-1865 (1971), 17.
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All your names I and my friend approve of or nearly all as to sense & expression, but I am frightened by their length & sound when compounded. As you will see I have taken deoxide and skaiode because they agree best with my natural standard East and West. I like Anode & Cathode better as to sound, but all to whom I have shewn them have supposed at first that by Anode I meant No way.
Letter (3 May 1834) to William Whewell, who coined the terms. In Frank A. J. L. James (ed.), The Correspondence of Michael Faraday (1993), Vol. 2, 181. Note: Here “No way” is presumably not an idiomatic exclamation, but a misinterpretation from the Greek prefix, -a “not”or “away from,” and hodos meaning “way.” The Greek ἄνοδος anodos means “way up” or “ascent.”
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An aromatic compound may be defined as a cyclic compound with a large resonance energy where all the annular atoms take part in a single conjugated system.
Electronic Theory of Organic Chemistry (1949), 160.
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An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.
In 'The Scientific Character of Geology', The Journal of Geology (Jul 1961), 69, No. 4, 458.
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And, to prevent mistakes, I must advertize you, that I now mean by elements, as those chymists that speak plainest do by their principles, certain primitive or simple, or perfectly unmingled bodies; which not being made of any other bodies, or of one another, are the ingredients of which all those called perfectly mixt bodies are immediately compounded, and into which they are ultimately resolved: now whether there be any such body to be constantly met with in all, and each, of those that are said to be elemented bodies, is the thing I now question.
The Sceptical Chemist (2nd ed., 1661), Appendix, 354. As given in Henry M. Leicester and Herbert S. Klickstein, A Source Book in Chemistry 1400-1900 (1952), 42.
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As mineralogy constitutes a part of chemistry, it is clear that this arrangement [of minerals] must derive its principles from chemistry. The most perfect mode of arrangement would certainly be to allow bodies to follow each other according to the order of their electro-chemical properties, from the most electro-negative, oxygen, to the most electro-positive, potassium; and to place every compound body according to its most electro-positive ingredient.
An Attempt to Establish a Pure Scientific System of Mineralogy (1814), trans. J. Black, 48.
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At the planet’s very heart lies a solid rocky core, at least five times larger than Earth, seething with the appalling heat generated by the inexorable contraction of the stupendous mass of material pressing down to its centre. For more than four billion years Jupiter’s immense gravitational power has been squeezing the planet slowly, relentlessly, steadily, converting gravitational energy into heat, raising the temperature of that rocky core to thirty thousand degrees, spawning the heat flow that warms the planet from within. That hot, rocky core is the original protoplanet seed from the solar system’s primeval time, the nucleus around which those awesome layers of hydrogen and helium and ammonia, methane, sulphur compounds and water have wrapped themselves.
Ben Bova
Jupiter
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Briefly, in the act of composition, as an instrument there intervenes and is most potent, fire, flaming, fervid, hot; but in the very substance of the compound there intervenes, as an ingredient, as it is commonly called, as a material principle and as a constituent of the whole compound the material and principle of fire, not fire itself. This I was the first to call phlogiston.
Specimen Beccherianum (1703). Trans. J. R. Partington, A History of Chemistry (1961), Vol. 2, 668.
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But I must confess I am jealous of the term atom; for though it is very easy to talk of atoms, it is very difficult to form a clear idea of their nature, especially when compounded bodies are under consideration.
'On the Absolute Quantity of Electricity Associated with the Particles or Atoms of Matter,' (31 Dec 1833), published in Philosophical Transactions (Jan 1834) as part of Series VII. Collected in Experimental Researches in Electricity: Reprinted from the Philosophical Transactions of 1831-1838 (1839), 256.
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But shall gravity be therefore called an occult cause, and thrown out of philosophy, because the cause of gravity is occult and not yet discovered? Those who affirm this, should be careful not to fall into an absurdity that may overturn the foundations of all philosophy. For causes usually proceed in a continued chain from those that are more compounded to those that are more simple; when we are arrived at the most simple cause we can go no farther ... These most simple causes will you then call occult and reject them? Then you must reject those that immediately depend on them.
Mathematical Principles (1729), 27.
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By blending water and minerals from below with sunlight and CO2 from above, green plants link the earth to the sky. We tend to believe that plants grow out of the soil, but in fact most of their substance comes from the air. The bulk of the cellulose and the other organic compounds produced through photosynthesis consists of heavy carbon and oxygen atoms, which plants take directly from the air in the form of CO2. Thus the weight of a wooden log comes almost entirely from the air. When we burn a log in a fireplace, oxygen and carbon combine once more into CO2, and in the light and heat of the fire we recover part of the solar energy that went into making the wood.
The Web of Life: A New Scientific Understanding of Living Systems (1997), 178.
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Carbon is, as may easily be shown and as I shall explain in greater detail later, tetrabasic or tetratomic, that is 1 atom of carbon = C = 12 is equivalent to 4 At.H.
'On the so-called Copulated Compounds and the Theory of Polyatomic Radicals', Annalen (1857), 4, 133. Trans. in J. R. Partington, A History of Chemistry (1972), Vol. 4, 536.
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Chymia, or Alchemy and Spagyrism, is the art of resolving compound bodies into their principles and of combining these again.
Fundamenta Chymiae (1720). Trans. J. R. Partington, A History of Chemistry (1961), Vol. 2, 664.
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Compare ... the various quantities of the same element contained in the molecule of the free substance and in those of all its different compounds and you will not be able to escape the following law: The different quantities of the same element contained in different molecules are all whole multiples of one and the same quantity, which always being entire, has the right to be called an atom.
Sketch of a Course of Chemical Philosophy (1858), Alembic Club Reprint (1910), 11.
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Compound interest is the most powerful force in the universe.
…...
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Compounds of gaseous substances with each other are always formed in very simple ratios, so that representing one of the terms by unity, the other is 1, 2, or at most 3 ... The apparent contraction of volume suffered by gas on combination is also very simply related to the volume of one of them.
Mémoires de la Société d' Arcueil, 1809, 2, 233-4. Trans. Foundations of the Molecular Theory, Alembic Club Reprint, no. 4 (1950), 24.
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Consider the hateful brew compounded with gleaming, deadly white lead whose fresh colour is like milk…. Over the victim’s jaws and in the grooves of the gums is plastered an astringent froth, and the furrow of the tongue turns rough on either side, and the depth of the throat grows somewhat dry, and from the pernicious venom follows a dry retching and hawking, for this affliction is severe; meanwhile his spirit sickens and he is worn out with mortal suffering. His body too grows chill, while sometimes his eyes behold strange illusions or else he drowses; nor can he bestir his limbs as heretofore, and he succumbs to the overmastering fatigue.
Nicander
As translated by A.S.F. Gow and A.F. Scholfield in Nicander: The Poems and Portical Fragments (1953), 99.
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Darwinian fitness is compounded of a mutual relationship between the organism and the environment. Of this, fitness of environment is quite as essential a component as the fitness which arises in the process of organic evolution; and in fundamental characteristics the actual environment is the fittest possible abode of life.
His thesis for the book stated at the beginning of The Fitness of the Environment (1913), Preface, v.
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During my stay in London I resided for a considerable time in Clapham Road in the neighbourhood of Clapham Common... One fine summer evening I was returning by the last bus 'outside' as usual, through the deserted streets of the city, which are at other times so full of life. I fell into a reverie (Träumerei), and 10, the atoms were gambolling before my eyes! Whenever, hitherto, these diminutive beings had appeared to me, they had always been in motion: but up to that time I had never been able to discern the nature of their motion. Now, however, I saw how, frequently, two smaller atoms united to form a pair: how the larger one embraced the two smaller ones: how still larger ones kept hold of three or even four of the smaller: whilst the whole kept whirling in a giddy dance. I saw how the larger ones formed a chain, dragging the smaller ones after them but only at the ends of the chain. I saw what our past master, Kopp, my highly honoured teacher and friend has depicted with such charm in his Molekular-Welt: but I saw it long before him. The cry of the conductor 'Clapham Road', awakened me from my dreaming: but I spent part of the night in putting on paper at least sketches of these dream forms. This was the origin of the 'Structural Theory'.
Kekule at Benzolfest in Berichte (1890), 23, 1302.
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Dust consisting of fine fibers of asbestos, which are insoluble and virtually indestructible, may become a public health problem in the near future. At a recent international conference on the biological effects of asbestos sponsored by the New York Academy of Sciences, participants pointed out on the one hand that workers exposed to asbestos dust are prone in later life to develop lung cancer, and on the other hand that the use of this family of fibrous silicate compounds has expanded enormously during the past few decades. A laboratory curiosity 100 years ago, asbestos today is a major component of building materials.
Magazine
In Scientific American (Sep 1964). As cited in '50, 100 & 150 Years Ago', Scientific American (Dec 2014), 311, No. 6, 98.
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Ethnologists regard man as the primitive element of tribes, races, and peoples. The anthropologist looks at him as a member of the fauna of the globe, belonging to a zoölogical classification, and subject to the same laws as the rest of the animal kingdom. To study him from the last point of view only would be to lose sight of some of his most interesting and practical relations; but to be confined to the ethnologist’s views is to set aside the scientific rule which requires us to proceed from the simple to the compound, from the known to the unknown, from the material and organic fact to the functional phenomenon.
'Paul Broca and the French School of Anthropology'. Lecture delivered in the National Museum, Washington, D.C., 15 April 1882, by Dr. Robert Fletcher. In The Saturday Lectures (1882), 118.
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Few scientists acquainted with the chemistry of biological systems at the molecular level can avoid being inspired. Evolution has produced chemical compounds exquisitely organized to accomplish the most complicated and delicate of tasks. Many organic chemists viewing crystal structures of enzyme systems or nucleic acids and knowing the marvels of specificity of the immune systems must dream of designing and synthesizing simpler organic compounds that imitate working features of these naturally occurring compounds.
In 'The Design of Molecular Hosts, Guests, and Their Complexes', Nobel Lecture, 8 December 1987. In Nobel Lectures: Chemistry 1981-1990 (1992), 419.
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Food is at present obtained almost entirely from the energy of the sunlight. The radiation from the sun produces from the carbonic acid in the air more or less complicated carbon compounds which serve us in plants and vegetables. We use the latent chemical energy of these to keep our bodies warm, we convert it into muscular effort. We employ it in the complicated process of digestion to repair and replace the wasted cells of our bodies. … If the gigantic sources of power become available, food would be produced without recourse to sunlight. Vast cellars, in which artificial radiation is generated, may replace the cornfields and potato patches of the world.
From 'Fifty Years Hence', Strand Magazine (Dec 1931). Reprinted in Popular Mechanics (Mar 1932), 57, No. 3, 396-397.
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Free men are aware of the imperfection inherent in human affairs, and they are willing to fight and die for that which is not perfect. They know that basic human problems can have no final solutions, that our freedom, justice, equality, etc. are far from absolute, and that the good life is compounded of half measures, compromises, lesser evils, and gropings toward the perfect. The rejection of approximations and the insistence on absolutes are the manifestation of a nihilism that loathes freedom, tolerance, and equity.
In The Temper of Our Time (1967), 103.
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From what has been said it is also evident, that the Whiteness of the Sun's Light is compounded all the Colours wherewith the several sorts of Rays whereof that Light consists, when by their several Refrangibilities they are separated from one another, do tinge Paper or any other white Body whereon they fall. For those Colours ... are unchangeable, and whenever all those Rays with those their Colours are mix'd again, they reproduce the same white Light as before.
Opticks (1704), Book 1, Part 2, Exper. XV, 114.
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Further study of the division phenomena requires a brief discussion of the material which thus far I have called the stainable substance of the nucleus. Since the term nuclear substance could easily result in misinterpretation..., I shall coin the term chromatin for the time being. This does not indicate that this substance must be a chemical compound of a definite composition, remaining the same in all nuclei. Although this may be the case, we simply do not know enough about the nuclear substances to make such an assumption. Therefore, we will designate as chromatin that substance, in the nucleus, which upon treatment with dyes known as nuclear stains does absorb the dye. From my description of the results of staining resting and dividing cells... it follows that the chromatin is distributed throughout the whole resting nucleus, mostly in the nucleoli, the network, and the membrane, but also in the ground-substance. In nuclear division it accumulates exclusively in the thread figures. The term achromatin suggests itself automatically for the unstainable substance of the nucleus. The terms chromatic and achromatic which will be used henceforth are thus explained.
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Gentlemen and ladies, this is ordinary alcohol, sometimes called ethanol; it is found in all fermented beverages. As you well know, it is considered by many to be poisonous, a belief in which I do not concur. If we subtract from it one CH2-group we arrive at this colorless liquid, which you see in this bottle. It is sometimes called methanol or wood alcohol. It is certainly more toxic than the ethanol we have just seen. Its formula is CH3OH. If, from this, we subtract the CH2-group, we arrive at a third colorless liquid, the final member of this homologous series. This compound is hydrogen hydroxide, best known as water. It is the most poisonous of all.
In Ralph Oesper, The Human Side of Scientists (1975), 189.
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How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.
Interview with American Analyst. Reprinted in Pacific Record of Medicine and Surgery (1886), 1, No. 3, 78.
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I have considered the two terms you want to substitute for eisode and exode, and upon the whole I am disposed to recommend instead of them anode and cathode. These words may signify eastern and western way, just as well as the longer compounds which you mention … I may mention too that anodos and cathodos are good, genuine Greek words, and not compounds coined for the purpose.
Letter to Michael Faraday (25 Apr 1834). Quoted in I. Todhunter (ed.), William Whewell: An Account of His Writings with Selections From His Literary and Scientific Correspondence (1876), Vol. 2, 179.
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I heard … xenon was a good anesthesia. … I thought, “How can xenon, which doesn’t form any chemical compounds, serve as a general anesthetic? … I lay awake at night for a few minutes before going to sleep, and during the next couple of weeks each night I would think, “…how do anesthetic agents work?" Then I forgot to do it after a while, but I’d trained my unconscious mind to keep this question alive and to call [it] to my consciousness whenever a new idea turned up…. So seven years went by. [One day I] put my feet up on the desk and started reading my mail, and here was a letter from George Jeffrey … an x-ray crystallographer, on his determination of the structure of a hydrate crystal. Immediately I sat up, took my feet off the desk, and said, “I understand anesthesia!” … I spent a year [and] determined the structure of chloroform hydrate, and then I wrote my paper published in June of 1961.
Interview with George B. Kauffman and Laurie M. Kauffman, in 'Linus Pauling: Reflections', American Scientist (Nov-Dec 1994), 82, No. 6, 522-523.
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I shall explain a System of the World differing in many particulars from any yet known, answering in all things to the common Rules of Mechanical Motions: This depends upon three Suppositions. First, That all Cœlestial Bodies whatsoever, have an attraction or gravitating power towards their own Centers, whereby they attract not only their own parts, and keep them from flying from them, as we may observe the Earth to do, but that they do also attract all the other Cœlestial bodies that are within the sphere of their activity; and consequently that not only the Sun and Moon have an influence upon the body and motion the Earth, and the Earth upon them, but that Mercury also Venus, Mars, Saturn and Jupiter by their attractive powers, have a considerable influence upon its motion in the same manner the corresponding attractive power of the Earth hath a considerable influence upon every one of their motions also. The second supposition is this, That all bodies whatsoever that are put into a direct and simple motion, will continue to move forward in a streight line, till they are by some other effectual powers deflected and bent into a Motion, describing a Circle, Ellipse, or some other more compounded Curve Line. The third supposition is, That these attractive powers are so much the more powerful in operating, by how much the nearer the body wrought upon is to their own Centers. Now what these several degrees are I have not yet experimentally verified; but it is a notion, which if fully prosecuted as it ought to be, will mightily assist the Astronomer to reduce all the Cœlestial Motions to a certain rule, which I doubt will never be done true without it. He that understands the nature of the Circular Pendulum and Circular Motion, will easily understand the whole ground of this Principle, and will know where to find direction in Nature for the true stating thereof. This I only hint at present to such as have ability and opportunity of prosecuting this Inquiry, and are not wanting of Industry for observing and calculating, wishing heartily such may be found, having myself many other things in hand which I would first compleat and therefore cannot so well attend it. But this I durst promise the Undertaker, that he will find all the Great Motions of the World to be influenced by this Principle, and that the true understanding thereof will be the true perfection of Astronomy.
An Attempt to Prove the Motion of the Earth from Observations (1674), 27-8. Based on a Cutlerian Lecture delivered by Hooke at the Royal Society four years earlier.
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I should like to call the number of atom groups, with which an elementary atom coordinates … to form a complex radical, the coordination number of the atom in question … We must differentiate between valence number and coordination number. The valence number indicates the maximum number of monovalent atoms which can be bound directly to the atom in question without the participation of other elementary atoms … Perhaps this concept [of coordination number] is destined to serve as a basis for the theory of the constitution of inorganic compounds, just as valence theory formed the basis for the constitutional theory of carbon compounds.
In 'Beitrag zur Konstitution anorganischer Verbindungen', Zeitschrift fur anorganische Chemie, (1893), 3, 267-330. Translated in George G. Kauffman (ed.), Classics in Coordination Chemistry: Part I: The Selected Papers of Alfred Werner (1968), 84-87.
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I think chemistry is being frittered away by the hairsplitting of the organic chemists; we have new compounds discovered, which scarcely differ from the known ones and when discovered are valueless—very illustrations perhaps of their refinements in analysis, but very little aiding the progress of true science.
Letter to William Grove (5 Jan 1845), The Letters of Faraday and Schoenbein, 1836-1862 (1899), Footnote, 209.
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I trust ... I have succeeded in convincing you that modern chemistry is not, as it has so long appeared, an ever-growing accumulation of isolated facts, as impossible for a single intellect to co-ordinate as for a single memory to grasp.
The intricate formulae that hang upon these walls, and the boundless variety of phenomena they illustrate, are beginning to be for us as a labyrinth once impassable, but to which we have at length discovered the clue. A sense of mastery and power succeeds in our minds to the sort of weary despair with which we at first contemplated their formidable array. For now, by the aid of a few general principles, we find ourselves able to unravel the complexities of these formulae, to marshal the compounds which they represent in orderly series; nay, even to multiply their numbers at our will, and in a great measure to forecast their nature ere we have called them into existence. It is the great movement of modern chemistry that we have thus, for an hour, seen passing before us. It is a movement as of light spreading itself over a waste of obscurity, as of law diffusing order throughout a wilderness of confusion, and there is surely in its contemplation something of the pleasure which attends the spectacle of a beautiful daybreak, something of the grandeur belonging to the conception of a world created out of chaos.
Concluding remark for paper presented at the Friday Discourse of the the Royal Institution (7 Apr 1865). 'On the Combining Power of Atoms', Proceedings of the Royal Institution (1865), 4, No. 42, 416.
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If we wish to give an account of the atomic constitution of the aromatic compounds, we are bound to explain the following facts:
1) All aromatic compounds, even the most simple, are relatively richer in carbon than the corresponding compounds in the class of fatty bodies.
2) Among the aromatic compounds, as well as among the fatty bodies, a large number of homologous substances exist.
3) The most simple aromatic compounds contain at least six atoms of carbon.
4) All the derivatives of aromatic substances exhibit a certain family likeness; they all belong to the group of 'Aromatic compounds'. In cases where more vigorous reactions take place, a portion of the carbon is often eliminated, but the chief product contains at least six atoms of carbon These facts justify the supposition that all aromatic compounds contain a common group, or, we may say, a common nucleus consisting of six atoms of carbon. Within this nucleus a more intimate combination of the carbon atoms takes place; they are more compactly placed together, and this is the cause of the aromatic bodies being relatively rich in carbon. Other carbon atoms can be joined to this nucleus in the same way, and according to the same law, as in the case of the group of fatty bodies, and in this way the existence of homologous compounds is explained.
Bulletin de la Societé Chimique de France (1865), 1, 98. Trans. W. H. Brock.
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If you could see what I almost daily see in my practice … persons … in the very last stages of wretched existence, emaciated to a skeleton, with both tables of the skull almost completely perforated in many places, half the nose gone, with rotten jaws, ulerated throats, breaths most pestiferous more intolerable than poisonous upas, limbs racked with the pains of the Inquisition, minds as imbecile as the puling babe, a grievous burden to themselves and a disgusting spectacle to others, you would exclaim as I have often done, 'O! the lamentable want of science that dictates the abuse (use) of that noxious drug calomel!'
[Calomel is the mercury compound, Hg2Cl2.]
Quoted in Wooster Beach, A Treatise on Anatomy, Physiology, and Health (1848), 177.
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In all chemical investigations, it has justly been considered an important object to ascertain the relative weights of the simples which constitute a compound. But unfortunately the enquiry has terminated here; whereas from the relative weights in the mass, the relative weights of the ultimate particles or atoms of the bodies might have been inferred, from which their number and weight in various other compounds would appear, in order to assist and to guide future investigations, and to correct their results. Now it is one great object of this work, to shew the importance and advantage of ascertaining the relative weights of the ultimate particles, both of simple and compound bodies, the number of simple elementary particles which constitute one compound particle, and the number of less compound particles which enter into the formation of one more compound particle.
If there are two bodies, A and B, which are disposed to combine, the following is the order in which the combinations may take place, beginning with the most simple: namely,
1 atom of A + 1 atom of B = 1 atom of C, binary
1 atom of A + 2 atoms of B = 1 atom of D, ternary
2 atoms of A + 1 atom of B = 1 atom of E, ternary
1 atom of A + 3 atoms of B = 1 atom of F, quaternary
3 atoms of A and 1 atom of B = 1 atom of G, quaternary
A New System of Chemical Philosophy (1808), Vol. 1, 212-3.
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In attempting to understand the elements out of which mental phenomena are compounded, it is of the greatest importance to remember that from the protozoa to man there is nowhere a very wide gap either in structure or in behaviour. From this fact it is a highly probable inference that there is also nowhere a very wide mental gap.
Lecture II, 'Instinct and Habit', The Analysis of Mind
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In deriving a body from the water type I intend to express that to this body, considered as an oxide, there corresponds a chloride, a bromide, a sulphide, a nitride, etc., susceptible of double compositions, or resulting from double decompositions, analogous to those presented by hydrochloric acid, hydrobromic acid, sulphuretted hydrogen, ammonia etc., or which give rise to the same compounds. The type is thus the unit of comparison for all the bodies which, like it, are susceptible of similar changes or result from similar changes.
Traité de Chimie Organique, 1856, 4, 587. Trans. J. R. Partington, A History of Chemistry, (1970), Vol. 4, 456.
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In every combustion there is disengagement of the matter of fire or of light. A body can burn only in pure air [oxygen]. There is no destruction or decomposition of pure air and the increase in weight of the body burnt is exactly equal to the weight of air destroyed or decomposed. The body burnt changes into an acid by addition of the substance that increases its weight. Pure air is a compound of the matter of fire or of light with a base. In combustion the burning body removes the base, which it attracts more strongly than does the matter of heat, which appears as flame, heat and light.
'Memoire sur la combustion en général', Mémoires de l'Académie des Sciences, 1777, 592. Reprinted in Oeuvres de Lavoisier (1864), Vol. 2, 225-33, trans. M. P. Crosland.
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In inorganic chemistry the radicals are simple; in organic chemistry they are compounds—that is the sole difference.
Joint paper with Liebig, but written by Dumas, Comptes Rendus 1837, 5, 567. Trans. J. R. Partington, A History of Chemistry, Vol. 4, 351.
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In one department of his [Joseph Black’s] lecture he exceeded any I have ever known, the neatness and unvarying success with which all the manipulations of his experiments were performed. His correct eye and steady hand contributed to the one; his admirable precautions, foreseeing and providing for every emergency, secured the other. I have seen him pour boiling water or boiling acid from a vessel that had no spout into a tube, holding it at such a distance as made the stream’s diameter small, and so vertical that not a drop was spilt. While he poured he would mention this adaptation of the height to the diameter as a necessary condition of success. I have seen him mix two substances in a receiver into which a gas, as chlorine, had been introduced, the effect of the combustion being perhaps to produce a compound inflammable in its nascent state, and the mixture being effected by drawing some string or wire working through the receiver's sides in an air-tight socket. The long table on which the different processes had been carried on was as clean at the end of the lecture as it had been before the apparatus was planted upon it. Not a drop of liquid, not a grain of dust remained.
In Lives of Men of Letters and Science, Who Flourished in the Time of George III (1845), 346-7.
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Incandescent carbon particles, by the tens of millions, leap free of the log and wave like banners, as flame. Several hundred significantly different chemical reactions are now going on. For example, a carbon atom and four hydrogen atoms, coming out of the breaking cellulose, may lock together and form methane, natural gas. The methane, burning (combining with oxygen), turns into carbon dioxide and water, which also go up the flue. If two carbon atoms happen to come out of the wood with six hydrogen atoms, they are, agglomerately, ethane, which bums to become, also, carbon dioxide and water. Three carbons and eight hydrogens form propane, and propane is there, too, in the fire. Four carbons and ten hydrogens—butane. Five carbons … pentane. Six … hexane. Seven … heptane. Eight carbons and eighteen hydrogens—octane. All these compounds come away in the breaking of the cellulose molecule, and burn, and go up the chimney as carbon dioxide and water. Pentane, hexane, heptane, and octane have a collective name. Logs burning in a fireplace are making and burning gasoline.
In 'Firewood', Pieces of the Frame (1975), 205-206.
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It cannot, of course, be stated with absolute certainty that no elements can combine with argon; but it appears at least improbable that any compounds will be formed.
[This held true for a century, until in Aug 2000, the first argon compound was formed, argon fluorohydride, HArF, but stable only below 40 K (−233 °C).]
Gases of the Atmosphere (1896), 193. Referenced in William H. Brock, The Chemical Tree: A History of Chemistry (2000), 339 and 671.
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It is often said that all the conditions for the first production of a living being are now present, which could ever have been present. But if (and oh what a big if) we could conceive in some warm little pond with all sort of ammonia and phosphoric salts—light, heat, electricity present, that a protein compound was chemically formed, ready to undergo still more complex changes, at the present such matter would be instantly devoured, or absorbed, which would not have been the case before living creatures were formed.
Letter (1 Feb 1871) to Joseph Dalton Hooker. In The Life and Letters of Charles Darwin (1888), Vol. 3, 18.
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It is often said that all the conditions for the first production of a living organism are now present, which could have ever been present. But if (and oh! what a big if!) we could conceive in some warm pond, with all sorts of ammonia and phosphoric salts, light, heat, electricity, &c., present, that a proteine compound was chemically formed ready to undergo still more complex changes, at the present day such matter would be instantly devoured or absorbed, which would not have been the case before living creatures were formed.
Letter; as quoted in The Origin of Life by J.D. Bernal (1967) publ.Weidenfeld and Nicholson, London
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It is, however, an argument of no weight to say that natural bodies are first generated or compounded out of those things into which they are at the last broken down or dissolved.
Disputations Touching the Generation of Animals (1651), trans. Gweneth Whitteridge (1981), Chapter 72, 389.
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It must ... be admitted that very simple relations ... exist between the volumes of gaseous substances and the numbers of simple or compound molecules which form them. The first hypothesis to present itself in this connection, and apparently even the only admissible one, is the supposition that the number of integral molecules in any gases is always the same for equal volumes, or always proportional to the volumes. Indeed, if we were to suppose that the number of molecules contained in a given volume were different for different gases, it would scarcely be possible to conceive that the law regulating the distance of molecules could give in all cases relations so simple as those which the facts just detailed compel us to acknowledge between the volume and the number of molecules.
'Essay on a Manner of Determining the Relative Masses of the Elementary Molecules of Bodies, and the Proportions in which they enter into these Compounds', Journal de Physique, 1811, 73, 58-76. In Foundations of the Molecular Theory; Alembic Club Reprints, Number 4 (1923), 28-9.
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It seeming impossible in any other manner to properly restrict the use of this powerful agent [calomel, a mercury compound, mercurous chloride], it is directed that it be struck from the supply table, and that no further requisitions for this medicine be approved by Medical Directors. ... modern pathology has proved the impropriety of the use of mercury in very many of those diseases in which it was formerly unfailingly administered. ... No doubt can exist that more harm has resulted from the misuse [of this agent], in the treatment of disease, than benefit from their proper administration.
W.A. Hammond, Surgeon General, Washington D.C., 4 May 1863
'Circular No. 6,', in William Grace, The Army Surgeon's Manual (1864), 121.
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It seems probable to me that God, in the beginning, formed matter in solid, massy, hard, impenetrable, moveable particles, of such sizes and figures, and with such other properties, and in such proportions to space, as most conduced to the end for which He formed them; and that these primitive particles, being solids, are incomparably harder than any porous bodies compounded of them, even so very hard as never to wear or break in pieces; no ordinary power being able to divide what God had made one in the first creation.
From Opticks (1704, 2nd ed., 1718), 375-376.
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It was his [Leibnitz’s] love of method and order, and the conviction that such order and harmony existed in the real world, and that our success in understanding it depended upon the degree and order which we could attain in our own thoughts, that originally was probably nothing more than a habit which by degrees grew into a formal rule. This habit was acquired by early occupation with legal and mathematical questions. We have seen how the theory of combinations and arrangements of elements had a special interest for him. We also saw how mathematical calculations served him as a type and model of clear and orderly reasoning, and how he tried to introduce method and system into logical discussions, by reducing to a small number of terms the multitude of compound notions he had to deal with. This tendency increased in strength, and even in those early years he elaborated the idea of a general arithmetic, with a universal language of symbols, or a characteristic which would be applicable to all reasoning processes, and reduce philosophical investigations to that simplicity and certainty which the use of algebraic symbols had introduced into mathematics.
A mental attitude such as this is always highly favorable for mathematical as well as for philosophical investigations. Wherever progress depends upon precision and clearness of thought, and wherever such can be gained by reducing a variety of investigations to a general method, by bringing a multitude of notions under a common term or symbol, it proves inestimable. It necessarily imports the special qualities of number—viz., their continuity, infinity and infinite divisibility—like mathematical quantities—and destroys the notion that irreconcilable contrasts exist in nature, or gaps which cannot be bridged over. Thus, in his letter to Arnaud, Leibnitz expresses it as his opinion that geometry, or the philosophy of space, forms a step to the philosophy of motion—i.e., of corporeal things—and the philosophy of motion a step to the philosophy of mind.
In Leibnitz (1884), 44-45. [The first sentence is reworded to better introduce the quotation. —Webmaster]
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It [the Euglena] is a perfect laboratory in itself, and it will act and react upon the water and the matters contained therein; converting them into new compounds resembling its own substance, and at the same time giving up portions of its own substance which have become effete.
From Address (22 Jul 1854) delivered at St. Martin’s Hall, published as a pamphlet (1854), 8, and collected in 'Educational Value of Natural History Sciences', Lay Sermons, Addresses, and Reviews (1870), 75.
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Knowledge of Nature is an account at bank, where each dividend is added to the principal and the interest is ever compounded; and hence it is that human progress, founded on natural knowledge, advances with ever increasing speed.
Concluding sentence of Address (11 Dec 1895) as President of the Geological Society, 'The Origin of Hypotheses, illustrated by the Discussion of a Topographical Problem', printed as Presidential Address of Grove Karl Gilbert (1896), 24. Also collected in Science (1896), 3, 13.
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Language is simply alive, like an organism. We all tell each other this, in fact, when we speak of living languages, and I think we mean something more than an abstract metaphor. We mean alive. Words are the cells of language, moving the great body, on legs. Language grows and evolves, leaving fossils behind. The individual words are like different species of animals. Mutations occur. Words fuse, and then mate. Hybrid words and wild varieties or compound words are the progeny. Some mixed words are dominated by one parent while the other is recessive. The way a word is used this year is its phenotype, but it has deeply immutable meanings, often hidden, which is its genotype.... The separate languages of the Indo-European family were at one time, perhaps five thousand years ago, maybe much longer, a single language. The separation of the speakers by migrations had effects on language comparable to the speciation observed by Darwin on various islands of the Galapagos. Languages became different species, retaining enough resemblance to an original ancestor so that the family resemblance can still be seen.
in 'Living Language,' The Lives of a Cell: Notes of a Biology Watcher, (1974, 1984), 106.
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Medicine is not only a science; it is also an art. It does not consist of compounding pills and plasters; it deals with the very processes of life, which must be understood before they may be guided.
…...
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Most, if not all, of the great ideas of modern mathematics have had their origin in observation. Take, for instance, the arithmetical theory of forms, of which the foundation was laid in the diophantine theorems of Fermat, left without proof by their author, which resisted all efforts of the myriad-minded Euler to reduce to demonstration, and only yielded up their cause of being when turned over in the blow-pipe flame of Gauss’s transcendent genius; or the doctrine of double periodicity, which resulted from the observation of Jacobi of a purely analytical fact of transformation; or Legendre’s law of reciprocity; or Sturm’s theorem about the roots of equations, which, as he informed me with his own lips, stared him in the face in the midst of some mechanical investigations connected (if my memory serves me right) with the motion of compound pendulums; or Huyghen’s method of continued fractions, characterized by Lagrange as one of the principal discoveries of that great mathematician, and to which he appears to have been led by the construction of his Planetary Automaton; or the new algebra, speaking of which one of my predecessors (Mr. Spottiswoode) has said, not without just reason and authority, from this chair, “that it reaches out and indissolubly connects itself each year with fresh branches of mathematics, that the theory of equations has become almost new through it, algebraic geometry transfigured in its light, that the calculus of variations, molecular physics, and mechanics” (he might, if speaking at the present moment, go on to add the theory of elasticity and the development of the integral calculus) “have all felt its influence”.
In 'A Plea for the Mathematician', Nature, 1, 238 in Collected Mathematical Papers, Vol. 2, 655-56.
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Mr. Dalton's aspect and manner were repulsive. There was no gracefulness belonging to him. His voice was harsh and brawling; his gait stiff and awkward; his style of writing and conversation dry and almost crabbed. In person he was tall, bony, and slender. He never could learn to swim: on investigating this circumstance he found that his spec. grav. as a mass was greater than that of water; and he mentioned this in his lectures on natural philosophy in illustration of the capability of different persons for attaining the art of swimming. Independence and simplicity of manner and originality were his best qualities. Though in comparatively humble circumstances he maintained the dignity of the philosophical character. As the first distinct promulgator of the doctrine that the elements of bodies unite in definite proportions to form chemical compounds, he has acquired an undying fame.
Dr John Davy's (brother of Humphry Davy) impressions of Dalton written in c.1830-31 in Malta.
John Davy
Quoted in W. C. Henry, Memoirs of the Life and Scientific Researches of John Dalton (1854), 217-8.
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My experiments proved that the radiation of uranium compounds ... is an atomic property of the element of uranium. Its intensity is proportional to the quantity of uranium contained in the compound, and depends neither on conditions of chemical combination, nor on external circumstances, such as light or temperature.
... The radiation of thorium has an intensity of the same order as that of uranium, and is, as in the case of uranium, an atomic property of the element.
It was necessary at this point to find a new term to define this new property of matter manifested by the elements of uranium and thorium. I proposed the word radioactivity which has since become generally adopted; the radioactive elements have been called radio elements.
In Pierre Curie, with the Autobiographical Notes of Marie Curie, trans. Charlotte and Vernon Kellogg (1923), 96. Also in reprint (2012) 45-46.
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My picture of the world is drawn in perspective and not like a model to scale. The foreground is occupied by human beings and the stars are all as small as three-penny bits. I don't really believe in astronomy, except as a complicated description of part of the course of human and possibly animal sensation. I apply my perspective not merely to space but also to time. In time the world will cool and everything will die; but that is a long time off still and its present value at compound discount is almost nothing.
From a paper read to the Apostles, a Cambridge discussion society (1925). In 'The Foundations of Mathematics' (1925), collected in Frank Plumpton Ramsey and D.H. Mellor (ed.), Philosophical Papers (1990), Epilogue, 249. Citation to the paper, in Nils-Eric Sahlin, The Philosophy of F.P. Ramsey (1990), 225.
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Not one of them [formulae] can be shown to have any existence, so that the formula of one of the simplest of organic bodies is confused by the introduction of unexplained symbols for imaginary differences in the mode of combination of its elements… It would be just as reasonable to describe an oak tree as composed of blocks and chips and shavings to which it may be reduced by the hatchet, as by Dr Kolbe’s formula to describe acetic acid as containing the products which may be obtained from it by destructive influences. A Kolbe botanist would say that half the chips are united with some of the blocks by the force parenthesis; the other half joined to this group in a different way, described by a buckle; shavings stuck on to these in a third manner, comma; and finally, a compound of shavings and blocks united together by a fourth force, juxtaposition, is joined to the main body by a fifth force, full stop.
'On Dr. Kolbe's Additive Formulae', Quarterly Journal of the Chemical Society (1855), 7, 133-4.
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Of the nucleosides from deoxyribonucleic acids, all that was known with any certainty [in the 1940s] was that they were 2-deoxy-­D-ribosides of the bases adenine, guanine, thymine and cytosine and it was assumed that they were structurally analogous to the ribonucleosides. The chemistry of the nucleotides—the phosphates of the nucleosides—was in a correspondingly primitive state. It may well be asked why the chemistry of these groups of compounds was not further advanced, particularly since we recognize today that they occupy a central place in the history of the living cell. True, their full significance was for a long time unrecognized and emerged only slowly as biochemical research got into its stride but I think a more important reason is to be found in the physical properties of compounds of the nucleotide group. As water-soluble polar compounds with no proper melting points they were extremely difficult to handle by the classic techniques of organic chemistry, and were accordingly very discouraging substances to early workers. It is surely no accident that the major advances in the field have coincided with the appearance of new experimental techniques such as paper and ion-exchange chromatography, paper electrophoresis, and countercurrent distribution, peculiarly appropriate to the compounds of this group.
In 'Synthesis in the Study of Nucleotides', Nobel Lecture, 11 December 1957. In Nobel Lectures: Chemistry 1942-1962 (1964), 524.
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One of the memorable moments of my life was when Willard Libby came to Princeton with a little jar full of crystals of barium xenate. A stable compound, looking like common salt, but much heavier. This was the magic of chemistry, to see xenon trapped into a crystal.
Letter to Oliver Sacks. Quoted in Oliver Sacks, Uncle Tungsten: Memories of a Chemical Boyhood (2001), footnote, 203.
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One of the most immediate consequences of the electrochemical theory is the necessity of regarding all chemical compounds as binary substances. It is necessary to discover in each of them the positive and negative constituents... No view was ever more fitted to retard the progress of organic chemistry. Where the theory of substitution and the theory of types assume similar molecules, in which some of the elements can be replaced by others without the edifice becoming modified either in form or outward behaviour, the electrochemical theory divides these same molecules, simply and solely, it may be said, in order to find in them two opposite groups, which it then supposes to be combined with each other in virtue of their mutual electrical activity... I have tried to show that in organic chemistry there exist types which are capable, without destruction, of undergoing the most singular transformations according to the nature of the elements.
Traité de Chemie Appliquée aux Arts, Vol. I (1828), 53. Trans. J. R. Partington, A History of Chemistry, Vol. 4, 366.
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Organic Chemistry has become a vast rubbish heap of puzzling and bewildering compounds.
Preface to A. W. Stewart, Recent Advances in Organic Chemistry (1908), xiii.
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Organic chemistry is the chemistry of carbon compounds. Biochemistry is the study of carbon compounds that crawl.
Often seen quoted, though without source, for example, in Vassilis Mougios, Exercise Biochemistry (2006), 1. [Please contact webmaster if you can identify the author and a primary source.]
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Recently, we’ve reported that we have made all five bases, the compounds that spell out the instructions for all life and are a part of the nucleic acids, RNA and DNA. Not only did we make all five bases but we found them in a meteorite! So that these two things coming together really assure us that the molecules necessary for life can be found in the absence of life. This was the biggest stumbling block.
In Space World (1985), 5, 25.
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Charles Babbage quote: Remember that accumulated knowledge, like accumulated capital, increases at compound interest: but it dif
Remember that accumulated knowledge, like accumulated capital, increases at compound interest: but it differs from the accumulation of capital in this; that the increase of knowledge produces a more rapid rate of progress, whilst the accumulation of capital leads to a lower rate of interest. Capital thus checks its own accumulation: knowledge thus accelerates its own advance. Each generation, therefore, to deserve comparison with its predecessor, is bound to add much more largely to the common stock than that which it immediately succeeds.
The Exposition of 1851: Or the Views of Industry, Science and Government of England (1851), 192-3.
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Scientific wealth tends to accumulate according to the law of compound interest. Every addition to knowledge of the properties of matter supplies the physical scientist with new instrumental means for discovering and interpreting phenomena of nature, which in their turn afford foundations of fresh generalisations, bringing gains of permanent value into the great storehouse of natural philosophy.
From Inaugural Address of the President to British Association for the Advancement of Science, Edinburgh (2 Aug 1871). Printed in The Chemical News (4 Aug 1871), 24, No. 610., 53.
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Surely something is wanting in our conception of the universe. We know positive and negative electricity, north and south magnetism, and why not some extra terrestrial matter related to terrestrial matter, as the source is to the sink. ... Worlds may have formed of this stuff, with element and compounds possessing identical properties with out own, indistinguishable from them until they are brought into each other's vicinity. ... Astronomy, the oldest and most juvenile of the sciences, may still have some surprises in store. Many anti-matter be commended to its care! ... Do dreams ever come true?
[Purely whimsical prediction long before the 1932 discovery of the positron, the antiparticle of the electron.]
'Potential Matter—A Holiday Dream', Letter to the Editor, Nature (18 Aug 1898), 58, 367. Quoted in Edward Robert Harrison, Cosmology: the Science of the Universe (2000), 433.
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The chemical compounds are comparable to a system of planets in that the atoms are held together by chemical affinity. They may be more or less numerous, simple or complex in composition, and in the constitution of the materials, they play the same role as Mars and Venus do in our planetary system, or the compound members such as our earth with its moon, or Jupiter with its satellites... If in such a system a particle is replaced by one of different character, the equilibrium can persist, and then the new compound will exhibit properties similar to those shown by the original substance.
Quoted in Ralph Oesper, The Human Side of Scientists (1975), 55.
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The discovery that these soccer-ball-like molecules can be made in large quantities will have an effect on chemistry like the sowing of a bucket of flower seeds—the results will spring up everywhere from now on. I’d be surprised if we don’t see thousands of new fullerene compounds in the next few years, some of which are almost certain to have important uses.
As quoted in Malcolm W. Browne, 'Bizarre New Class of Molecules Spawns Its Own Branch of Chemistry', New York Times (25 Dec 1990), Late Edition (East Coast), L37.
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The frequency of disastrous consequences in compound fracture, contrasted with the complete immunity from danger to life or limb in simple fracture, is one of the most striking as well as melancholy facts in surgical practice.
'On a New Method of Treating Compound Fracture, Abscesses, etc: With Observations on the Conditions of Supperation', Part I, The Lancet (1867), 326.
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The genotypic constitution of a gamete or a zygote may be parallelized with a complicated chemico-physical structure. This reacts exclusively in consequence of its realized state, but not in consequence of the history of its creation. So it may be with the genotypical constitution of gametes and zygotes: its history is without influence upon its reactions, which are determined exclusively by its actual nature. The genotype-conception is thus an 'ahistoric' view of the reactions of living beings—of course only as far as true heredity is concerned. This view is an analog to the chemical view, as already pointed out; chemical compounds have no compromising ante-act, H2O is always H2O, and reacts always in the same manner, whatsoever may be the 'history' of its formation or the earlier states of its elements. I suggest that it is useful to emphasize this 'radical' ahistoric genotype-conception of heredity in its strict antagonism to the transmission—or phenotype-view.
'The Genotype Conception of Heredity', The American Naturalist (1911), 45, 129.
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The glimpses of chemical industry's services to man afforded by this book could be presented only by utilizing innumerable chemical products. The first outline of its plan began to take shape on chemically produced notepaper with the aid of a chemically-treated graphite held in a synthetic resin pencil. Early corrections were made with erasers of chemically compounded rubber. In its ultimate haven on the shelves of your bookcase, it will rest on a coating of chemical varnish behind a pane of chemically produced glass. Nowhere has it been separated from that industry's products.
Man in a Chemical World (1937), L'Envoi, 284.
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The Greeks are wrong to recognize coming into being and perishing; for nothing comes into being nor perishes, but is rather compounded or dissolved from things that are. So they would be right to call coming into being composition and perishing dissolution.
Simplicius, Commentary on Aristotle’s Physics, 163,20-4. In G. S. Kirk, J. E. Raven and M. Schofield (eds.), The Presocratic Philosophers: A Critical History with a Selection of Texts (1983), p. 358.
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The material universe must consist ... of bodies ... such that each of them exercises its own separate, independent, and invariable effect, a change of the total state being compounded of a number of separate changes each of which is solely due to a separate portion of the preceding state.
A Treatise on Probability (), 249. In Antony Flew, A Dictionary of Philosophy (1984), 30.
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The most fundamental difference between compounds of low molecular weight and macromolecular compounds resides in the fact that the latter may exhibit properties that cannot be deduced from a close examination of the low molecular weight materials. Not very different structures can be obtained from a few building blocks; but if 10,000 or 100,000 blocks are at hand, the most varied structures become possible, such as houses or halls, whose special structure cannot be predicted from the constructions that are possible with only a few building blocks... Thus, a chromosome can be viewed as a material whose macromolecules possess a well defined arrangement, like a living room in which each piece of furniture has its place and not, as in a warehouse, where the pieces of furniture are placed together in a heap without design.
Quoted, without citation, in Ralph E. Oesper (ed.), The Human Side of Scientists (1975), 175.
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The most powerful force in the universe is compound interest.
…...
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The only difference between elements and compounds consists in the supposed impossibility of proving the so-called elements to be compounds.
'Faraday Lecture: Elements and Compounds', Journal of the Chemical Society (1904), 85, 520.
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The precise equivalence of the chromosomes contributed by the two sexes is a physical correlative of the fact that the two sexes play, on the whole, equal parts in hereditary transmission, and it seems to show that the chromosomal substance, the chromatin, is to be regarded as the physical basis of inheritance. Now, chromatin is known to be closely similar to, if not identical with, a substance known as nuclein (C29H49N9O22, according to Miescher), which analysis shows to be a tolerably definite chemical compased of nucleic acid (a complex organic acid rich in phosphorus) and albumin. And thus we reach the remarkable conclusion that inheritance may, perhaps, be effected by the physical transmission of a particular chemical compound from parent to offspring.
In An Atlas of the Fertilization and Karyokinesis of the Ovum (1895), 4.
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The progress of synthesis, or the building up of natural materials from their constituent elements, proceeds apace. Even some of the simpler albuminoids, a class of substances of great importance in the life process, have recently been artificially prepared. ... Innumerable entirely new compounds have been produced in the last century. The artificial dye-stuffs, prepared from materials occurring in coal-tar, make the natural colours blush. Saccharin, which is hundreds of times sweeter than sugar, is a purely artificial substance. New explosives, drugs, alloys, photographic substances, essences, scents, solvents, and detergents are being poured out in a continuous stream.
In Matter and Energy (1912), 45-46.
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The term element is applied in chemistry to those forms of matter which have hitherto resisted all attempts to decompose them. Nothing is ever meant to be affirmed concerning their real nature; they are simply elements to us at the present time; hereafter, by new methods of research, or by new combinations of those already possessed by science, many of the substances which now figure as elements may possibly be shown to be compounds; this has already happened, and may again take place.
In Elementary Chemistry, Theoretical and Practical (1854), 103. There follows on this page, 62 listed elements, some indicated as “of recent discovery and yet imperfectly known”. Two of the later names were Norium and Pelopium.
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The trick in discovering evolutionary laws is the same as it is in discovering laws of physics or chemistry—namely, finding the right level of generalization to make prediction possible. We do not try to find a law that says when and where explosions will occur. We content ourselves with saying that certain sorts of compounds are explosive under the right conditions, and we predict that explosions will occur whenever those conditions are realized.
In 'Paleoanthropology: Science or Mythical Charter?', Journal of Anthropological Research (Summer 2002), 58, No. 2, 193.
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There is an occasional glimmer of fertility [as compounds], the chemical equivalent of a blade of grass [in a desert]. So, gone … is the justification for “inert.” [Group 0 elements] are now known collectively as the noble gases, a name intended to imply a kind of chemical aloofness rather than a rigorous chastity.
In The Periodic Kingdom: A Journey Into the Land of the Chemical Elements (1995), 9.
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There is deposited in them [plants] an enormous quantity of potential energy [Spannkräfte], whose equivalent is provided to us as heat in the burning of plant substances. So far as we know at present, the only living energy [lebendige Kraft] absorbed during plant growth are the chemical rays of sunlight… Animals take up oxygen and complex oxidizable compounds made by plants, release largely as combustion products carbonic acid and water, partly as simpler reduced compounds, thus using a certain amount of chemical potential energy to produce heat and mechanical forces. Since the latter represent a relatively small amount of work in relation to the quantity of heat, the question of the conservation of energy reduces itself roughly to whether the combustion and transformation of the nutritional components yields the same amount of heat released by animals.
Wissenschaftliche Abhandlungen (1847), 66. Trans. Joseph S. Fruton, Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology (1999), 247.
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There is no sharp boundary line separating the reactions of the immune bodies from chemical processes between crystalloids, just as in nature there exists every stage between crystalloid and colloid. The nearer the colloid particle approximates to the normal electrolyte, the nearer its compounds must obviously come to conforming to the law of simple stoichiometric proportions, and the compounds themselves to simple chemical compounds. At this point, it should be recalled that Arrhenius has shown that the quantitative relationship between toxin and antitoxin is very similar to that between acid and base.
Landsteiner and Nicholas von Jagic, 'Uber Reaktionen anorganischer Kolloide und Immunkorper', Münchener medizinischer Wochenschrift (1904), 51, 1185-1189. Trans. Pauline M. H. Mazumdar.
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This investigation has yielded an unanticipated result that reaction of cyanic acid with ammonia gives urea, a noteworthy result in as much as it provides an example of the artificial production of an organic, indeed a so-called animal, substance from inorganic substances.
[The first report of the epoch-making discovery, that an organic compound can be produced from inorganic substances.]
In 'On the Artificial Formation of Urea'. In J.C. Poggendorff's Annalen der Physik und Chemie (1828), 88, 253. Alternate translation in 'Über Künstliche Bildung des Hamstoffs', Annalen der Physik und Chemie (1828), 12, 253, as translated in Quarterly Journal of Science (Apr-Jun 1828), 25, 491. Collected in Henry Marshall Leicester and Herbert S. Klickstein, A Source Book in Chemistry, 1400-1900 (1951), 310.
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This is the excellent foppery of the world: that when we are sick in fortune—often the surfeits of our own behaviour—we make guilty of our disasters the sun, the moon, and stars, as if we were villains on necessity, fools by heavenly compulsion, knaves, thieves, and treachers by spherical predominance, drunkards, liars, and adulterers, by an enforced obedience of planetary influence, and all that we are evil in, by a divine thrusting on. An admirable evasion of whoremaster man, to lay his goatish disposition on the charge of a star! My father compounded with my mother under the Dragon's tail and my nativity was under Ursa Major, so that it follows that I am rough and lecherous. Fut! I should have been that I am had the maidenliest star in the firmament twinkled on my bastardizing.
King Lear (1605-6), I, ii.
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Those of us who were familiar with the state of inorganic chemistry in universities twenty to thirty years ago will recall that at that time it was widely regarded as a dull and uninteresting part of the undergraduate course. Usually, it was taught almost entirely in the early years of the course and then chiefly as a collection of largely unconnected facts. On the whole, students concluded that, apart from some relationships dependent upon the Periodic table, there was no system in inorganic chemistry comparable with that to be found in organic chemistry, and none of the rigour and logic which characterised physical chemistry. It was widely believed that the opportunities for research in inorganic chemistry were few, and that in any case the problems were dull and uninspiring; as a result, relatively few people specialized in the subject... So long as inorganic chemistry is regarded as, in years gone by, as consisting simply of the preparations and analysis of elements and compounds, its lack of appeal is only to be expected. The stage is now past and for the purpose of our discussion we shall define inorganic chemistry today as the integrated study of the formation, composition, structure and reactions of the chemical elements and compounds, excepting most of those of carbon.
Inaugural Lecture delivered at University College, London (1 Mar 1956). In The Renaissance of Inorganic Chemistry (1956), 4-5.
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To many physical chemists in the 1920's and early 1930's, the organic chemist was a grubby artisan engaged in an unsystematic search for new compounds, a search which was strongly influenced by the profit motive.
'Physical Organic Chemistry in Retrospect', Journal of Chemical Education, 1966, 43, 464.
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TRUTH, n. An ingenious compound of desirability and appearance. Discovery of truth is the sole purpose of philosophy, which is the most ancient occupation of the human mind and has a fair prospect of existing with increasing activity to the end of time.
The Collected Works of Ambrose Bierce (1911), Vol. 7, The Devil's Dictionary,  352.
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We define organic chemistry as the chemistry of carbon compounds.
Lehrbuch der Organischen Chemie (1861), Vol. 1, 11. Trans. W. H. Brock.
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We maintain that there are two exhalations, one vaporous the other smoky, and these correspond to two kinds of bodies that originate in the earth, things quarried and things mined. The heat of the dry exhalation is the cause of all things quarried. Such are the kinds of stones that cannot be melted, and realgar, and ochre, and ruddle, and sulphur, and the other things of that kind, most things quarried being either coloured lye or, like cinnabar, a stone compounded of it. The vaporous exhalation is the cause of all things mined—things which are either fusible or malleable such as iron, copper, gold.
Aristotle
Meteorology, 378a, 19-28. In Jonathan Barnes (ed.), The Complete Works of Aristotle (1984), Vol. I, 607.
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We may regard [Scheele] not only as having given the first indication of the rich harvest to be reaped by the investigation of the compounds of organic chemistry, but as having been the first to discover and make use of characteristic reactions by which closely allied substances can be detected and separated, so that he must be considered one of the chief founders of analytical chemistry.
In Treatise on Chemistry (1877, 1890), Vol. 1, 23.
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When an element A has an affinity for another substance B, I see no mechanical reason why it should not take as many atoms of B as are presented to it, and can possibly come into contact with it (which may probably be 12 in general), except so far as the repulsion of the atoms of B among themselves are more than a match for the attraction of an atom of A. Now this repulsion begins with 2 atoms of B to 1 atom of A, in which case the 2 atoms of B are diametrically opposed; it increases with 3 atoms of B to 1 of A, in which case the atoms are only 120° asunder; with 4 atoms of B it is still greater as the distance is then only 90; and so on in proportion to the number of atoms. It is evident from these positions, that, as far as powers of attraction and repulsion are concerned (and we know of no other in chemistry), binary compounds must first be formed in the ordinary course of things, then ternary and so on, till the repulsion of the atoms of B (or A, whichever happens to be on the surface of the other), refuse to admit any more.
Observations on Dr. Bostock's Review of the Atomic Principles of Chemistry', Nicholson's Journal, 1811, 29, 147.
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When carbon (C), Oxygen (o) and hydrogen (H) atoms bond in a certain way to form sugar, the resulting compound has a sweet taste. The sweetness resides neither in the C, nor in the O, nor in the H; it resides in the pattern that emerges from their interaction. It is an emergent property. Moreover, strictly speaking, is not a property of the chemical bonds. It is a sensory experience that arises when the sugar molecules interact with the chemistry of our taste buds, which in turns causes a set of neurons to fire in a certain way. The experience of sweetness emerges from that neural activity.
In The Hidden Connections (2002), 116-117.
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When the formulae of inorganic chemical compounds are considered, even a superficial observer is struck with the general symmetry of their construction; the compounds of nitrogen, phosphorus, antimony and arsenic especially exhibit the tendency of the elements to form compounds containing 3 or 5 equivs. of other elements, and it is in these proportions that their affinities are best satisfied; thus in the ternal group we have NO3, NH3, NI3, NS3, PO3, PH3, PCl3, SbO3, SbH3, SbCl3, AsO3, AsH3, AsCl3 &c; and in the five-atom group NO4, NH4O, NH4I, PO5, PH4I, &c. Without offering any hypothesis regarding the cause of this symmetrical grouping of atoms, it is sufficiently evident, from the examples just given, that such a tendency or law prevails, and that, no matter what the character of the uniting atoms may be, the combining power of the attracting element, if I may be allowed the term, is always satisfied by the same number of these atoms.
'On a New Series of Organic Bodies Containing Metals', Philosophical Transactions of the Royal Society of London, 1852, 14:2, 440.
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When the simplest compounds of this element are considered (marsh gas, chloride of carbon, chloroform, carbonic acid, phosgene, sulphide of carbon, hydrocyanic acid, etc.) it is seen that the quantity of carbon which chemists have recognised as the smallest possible, that is, as an atom, always unites with 4 atoms of a monatomic or with two atoms of a diatomic element; that in general, the sum of the chemical units of the elements united with one atom of carbon is 4. This leads us to the view that carbon is tetratomic or tetrabasic. In the cases of substances which contain several atoms of carbon, it must be assumed that at least some of the atoms are in some way held in the compound by the affinity of carbon, and that the carbon atoms attach themselves to one another, whereby a part of the affinity of the one is naturally engaged with an equal part of the affinity of the other. The simplest and therefore the most probable case of such an association of carbon atoms is that in which one affinity unit of one is bound by one of the other. Of the 2 x 4 affinity units of the two carbon atoms, two are used up in holding the atoms together, and six remain over, which can be bound by atom)' of other elements.
'Ueber die Konstitution und die Metamorphosen der chemischen Verbindungen', Annalen (1858) 5, 106. Trans. in J. R. Partington, A History of Chemistry (1972), Vol. 4, 536.
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When ultra-violet light acts on a mixture of water, carbon dioxide, and ammonia, a vast variety of organic substances are made, including sugars and apparently some of the materials from which proteins are built up…. But before the origin of life they must have accumulated till the primitive oceans reached the consistency of hot dilute soup…. The first living or half-living things were probably large molecules synthesized under the influence of the sun’s radiation, and only capable of reproduction in the particularly favorable medium in which they originated….
In 'The Origin of Life', The Inequality of Man: And Other Essays (1932, 1937), 152.
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Without preparing fluorine, without being able to separate it from the substances with which it is united, chemistry has been able to study and to analyze a great number of its compounds. The body was not isolated, and yet its place was marked in our classifications. This well demonstrates the usefulness of a scientific theory, a theory which is regarded as true during a certain time, which correlates facts and leads the mind to new hypotheses, the first causes of experimentation; which, little by little, destroy the theory itself, in order to replace it by another more in harmony with the progress of science.
[Describing the known history of fluorine compounds before his isolation of the element.]
'Fluorine', lecture at the Royal Institution (28 May 1897), translated from the French, in Proceedings of the Royal Institution (1897). In Annual Report of the Board of Regents of the Smithsonian Institution to July 1897 (1898), 262.
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[The] structural theory is of extreme simplicity. It assumes that the molecule is held together by links between one atom and the next: that every kind of atom can form a definite small number of such links: that these can be single, double or triple: that the groups may take up any position possible by rotation round the line of a single but not round that of a double link: finally that with all the elements of the first short period [of the periodic table], and with many others as well, the angles between the valencies are approximately those formed by joining the centre of a regular tetrahedron to its angular points. No assumption whatever is made as to the mechanism of the linkage. Through the whole development of organic chemistry this theory has always proved capable of providing a different structure for every different compound that can be isolated. Among the hundreds of thousands of known substances, there are never more isomeric forms than the theory permits.
Presidential Address to the Chemical Society (16 Apr 1936), Journal of the Chemical Society (1936), 533.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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Bronislaw Malinowski
Bible
Thomas Huxley
Alessandro Volta
Erwin Schrodinger
Wilhelm Roentgen
Louis Pasteur
Bertrand Russell
Jean Lamarck
- 70 -
Samuel Morse
John Wheeler
Nicolaus Copernicus
Robert Fulton
Pierre Laplace
Humphry Davy
Thomas Edison
Lord Kelvin
Theodore Roosevelt
Carolus Linnaeus
- 60 -
Francis Galton
Linus Pauling
Immanuel Kant
Martin Fischer
Robert Boyle
Karl Popper
Paul Dirac
Avicenna
James Watson
William Shakespeare
- 50 -
Stephen Hawking
Niels Bohr
Nikola Tesla
Rachel Carson
Max Planck
Henry Adams
Richard Dawkins
Werner Heisenberg
Alfred Wegener
John Dalton
- 40 -
Pierre Fermat
Edward Wilson
Johannes Kepler
Gustave Eiffel
Giordano Bruno
JJ Thomson
Thomas Kuhn
Leonardo DaVinci
Archimedes
David Hume
- 30 -
Andreas Vesalius
Rudolf Virchow
Richard Feynman
James Hutton
Alexander Fleming
Emile Durkheim
Benjamin Franklin
Robert Oppenheimer
Robert Hooke
Charles Kettering
- 20 -
Carl Sagan
James Maxwell
Marie Curie
Rene Descartes
Francis Crick
Hippocrates
Michael Faraday
Srinivasa Ramanujan
Francis Bacon
Galileo Galilei
- 10 -
Aristotle
John Watson
Rosalind Franklin
Michio Kaku
Isaac Asimov
Charles Darwin
Sigmund Freud
Albert Einstein
Florence Nightingale
Isaac Newton



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