Ask a follower of Bacon what [science] the new philosophy, as it was called in the time of Charles the Second, has effected for mankind, and his answer is ready; “It has lengthened life; it has mitigated pain; it has extinguished diseases; it has increased the fertility of the soil; it has given new securities to the mariner; it has furnished new arms to the warrior; it has spanned great rivers and estuaries with bridges of form unknown to our fathers; it has guided the thunderbolt innocuously from heaven to earth; it has lighted up the night with the splendour of the day; it has extended the range of the human vision; it has multiplied the power of the human muscles; it has accelerated motion; it has annihilated distance; it has facilitated intercourse, correspondence, all friendly offices, all dispatch of business; it has enabled man to descend to the depths of the sea, to soar into the air, to penetrate securely into the noxious recesses of the earth, to traverse the land in cars which whirl along without horses, to cross the ocean in ships which run ten knots an hour against the wind. These are but a part of its fruits, and of its first-fruits; for it is a philosophy which never rests, which has never attained, which is never perfect. Its law is progress. A point which yesterday was invisible is its goal to-day, and will be its starting-point to-morrow.”

If you could see what I almost daily see in my practice … persons … in the very last stages of wretched existence, emaciated to a skeleton, with both tables of the skull almost completely perforated in many places, half the nose gone, with rotten jaws, ulerated throats, breaths most pestiferous more intolerable than poisonous upas, limbs racked with the pains of the Inquisition, minds as imbecile as the puling babe, a grievous burden to themselves and a disgusting spectacle to others, you would exclaim as I have often done, 'O! the lamentable want of science that dictates the abuse (use) of that noxious drug calomel!'
[Calomel is the mercury compound, Hg₂Cl₂.]

It was a great step in science when men became convinced that, in order to understand the nature of things, they must begin by asking, not whether a thing is good or bad, noxious or beneficial, but of what kind it is? And how much is there of it? Quality and Quantity were then first recognised as the primary features to be observed in scientific inquiry.

The most important object of Civil Engineering is to improve the means of production and of traffic in states, both for external and internal trade. It is applied in the construction and management of roads, bridges, railroads, aqueducts, canals, river navigation, docks and storehouses, for the convenience of internal intercourse and exchange; and in the construction of ports, harbours, moles, breakwaters and lighthouses; and in the navigation by artificial power for the purposes of commerce. It is applied to the protection of property where natural powers are the sources of injury, as by embankments forthe defence of tracts of country from the encroachments of the sea, or the overflowing of rivers; it also directs the means of applying streams and rivers to use, either as powers to work machines, or as supplies for the use of cities and towns, or for irrigation; as well as the means of removing noxious accumulations, as by the drainage of towns and districts to ... secure the public health.

The question of protection against the noxious action of the X rays appears to be assuming more and more importance, as we begin to recognise the searching nature of their action on the deep-seated tissues and their far-reaching therapeutic effect on the internal organs.

The war on drugs must be a metaphorical war. But that … has to do with our stubborn determination not to come to grips with what a drug is: … our refusal to recognize that the term “drug” is not only a medical but also a political concept. … In short, while seemingly the word “drug” is a part of the vocabulary of science, it is even more importantly a part of the vocabulary of politics. … A drug is either good or bad, effective or ineffective, therapeutic or noxious, licit or illicit. … We deploy them simultaneously as technical tools in our fight against medical diseases and as scapegoats in our struggle for personal security and political stability.

We can make an exception of opium “which the creator seems to prescribe, as we often see the scarlet poppy growing in the corn fields” but all other receipts of Omniscience must be condemned. The purple fox-glove, the many-tinted veratrum the lilac stramonium they are all “'noxious” but a little opium it helps the imagination.
[Criticizing the medical use of noxious psychoactive drugs.]

When air has been freshly and strongly tainted with putrefaction, so as to smell through the water, sprigs of mint have presently died, upon being put into it, their leaves turning black; but if they do not die presently, they thrive in a most surprizing manner. In no other circumstances have I ever seen vegetation so vigorous as in this kind of air, which is immediately fatal to animal life. Though these plants have been crouded in jars filled with this air, every leaf has been full of life; fresh shoots have branched out in various , and have grown much faster than other similiar plants, growing in the same exposure in common air.
This observation led me to conclude that plants, instead of affecting the air in the same manner with animal respiration, reverse the effects of breathing, and tend to keep the atmosphere sweet and wholesome, when it is become noxious, in consequence on animals living and breathing, or dying and putrefying in it.
In order to ascertain this, I took a quantity of air, made thoroughly noxious, by mice breathing and dying in it, and divided it into two parts; one of which I put into a phial immersed in water; and to the other (which was contained in a glass jar, standing in water) I put a sprig of mint. This was about the beginning of August 1771, and after eight or nine days, I found that a mouse lived perfectly well in that part of the air, in which the sprig of mint had grown, but died the moment it was put into the other part of the same original quantity of air; and which I had kept in the very same exposure, but without any plant growing in it.