Pour accomplir de grandes choses il ne suffit pas d'agir il faut rêver; il ne suffit pas de calculer, il faut croire.
To accomplish great things, we must not only act but also dream, not only plan but also believe.
[Referring to the Suez Canal, initiated by Ferdinand de Lesseps.]

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.

An undertaking of great magnitude and importance, the successful accomplishment of which, in so comparatively short a period, notwithstanding the unheard of unestimable difficulties and impediments which had to be encountered and surmounted, in an almost unexplored and uninhabited wilderness … evinced on your part a moral courage and an undaunted spirit and combination of science and management equally exciting our admiration and deserving our praise.
(In recognition of his achievement building the Rideau Canal.)

i² = j² = k² = ijk = - 1
[This representation was devised on 16th Oct 1843, and which he carved into a stone of Brougham Bridge, over the Royal Canal, Dublin. It has since worn away.]

In Amsterdam the water is the mistress and the land the vassal, throughout the city there are as many canals and drawbridges as bracelets on a Gypsy’s bronzed arms.

It certainly strikes the beholder with astonishment, to perceive what vast difficulties can be overcome by the pigmy arms of little mortal man, aided by science and directed by superior skill.

It is raining DNA outside. On the bank of the Oxford canal at the bottom of my garden is a large willow tree, and it is pumping downy seeds into the air. ... [spreading] DNA whose coded characters spell out specific instructions for building willow trees that will shed a new generation of downy seeds. … It is raining instructions out there; it’s raining programs; it’s raining tree-growing, fluff-spreading, algorithms. That is not a metaphor, it is the plain truth. It couldn’t be any plainer if it were raining floppy discs.

It is the destiny of the sciences, which must necessarily be in the hands of a few, that the utility of their progress should be invisible to the greater part of mankind, especially if those sciences are associated with unobtrusive pursuits. Let a greater facility in using our navigable waters and opening new lines of communication but once exist, simply because at present we know vastly better how to level the ground and construct locks and flood-gates—what does it amount to? The workmen have had their labors lightened, but they themselves have not the least idea of the skill of the geometer who directed them; they have been put in motion nearly as the body is by a soul of which it knows nothing; the rest of the world has even less perception of the genius which presided over the enterprise, and enjoys the success it has attained only with a species of ingratitude.

My impression about the Panama Canal is that the great revolution it is going to introduce in the trade of the world is in the trade between the east and the west coast of the United States.

Since 1849 I have studied incessantly, under all its aspects, a question which was already in my mind [since 1832. I confess that my scheme is still a mere dream, and I do not shut my eyes to the fact that so long as I alone believe it to be possible, it is virtually impossible. ... The scheme in question is the cutting of a canal through the Isthmus of Suez. This has been thought of from the earliest historical times, and for that very reason is looked upon as impracticable. Geographical dictionaries inform us indeed that the project would have been executed long ago but for insurmountable obstacles. [On his inspiration for the Suez Canal.]

Subtle as the mind is it can effect little without knowledge. It cannot construct a bridge, or a building, or make a canal, or work a problem in algebra, unless it is provided with information.

The central nerve chain of an invertebrate such as the lobster runs beneath its alimentary canal, whereas the main portion of its rudimentary brain is placed above it, in its forehead. In other words, the lobster’s gullet, from mouth to stomach, has to pass through the midst of its brain ganglia. If its brain were to expand—and expand it must if the lobster is to grow in wisdom—its gullet would be squeezed and it would starve.

The digestive canal is in its task a complete chemical factory. The raw material passes through a long series of institutions in which it is subjected to certain mechanical and, mainly, chemical processing, and then, through innumerable side-streets, it is brought into the depot of the body. Aside from this basic series of institutions, along which the raw material moves, there is a series of lateral chemical manufactories, which prepare certain reagents for the appropriate processing of the raw material.

The energy liberated when substrates undergo air oxidation is not liberated in one large burst, as was once thought, but is released in stepwise fashion. At least six separate steps seem to be involved. The process is not unlike that of locks in a canal. As each lock is passed in the ascent from a lower to a higher level a certain amount of energy is expended. Similarly, the total energy resulting from the oxidation of foodstuffs is released in small units or parcels, step by step. The amount of free energy released at each step is proportional to the difference in potential of the systems comprising the several steps.

The most important object of Civil Engineering is to improve the means of production and of traffic in states, both for external and internal trade. It is applied in the construction and management of roads, bridges, railroads, aqueducts, canals, river navigation, docks and storehouses, for the convenience of internal intercourse and exchange; and in the construction of ports, harbours, moles, breakwaters and lighthouses; and in the navigation by artificial power for the purposes of commerce. It is applied to the protection of property where natural powers are the sources of injury, as by embankments forthe defence of tracts of country from the encroachments of the sea, or the overflowing of rivers; it also directs the means of applying streams and rivers to use, either as powers to work machines, or as supplies for the use of cities and towns, or for irrigation; as well as the means of removing noxious accumulations, as by the drainage of towns and districts to ... secure the public health.

The Panama Canal was dug with a microscope.

The President shall then, through the Isthmian Canal Commission … cause to be excavated, constructed and completed, utilizing to that end, as far as practicable, the work heretofore done by the New Panama Canal Company, of France, and its predecessor company, a ship canal from the Caribbean Sea to the Pacific Ocean. Such canal shall he of sufficient capacity and depth as shall afford convenient passage for vessels of the largest tonnage and greatest draft now in use, and such as may reasonably be anticipated, and shall be supplied with all necessary locks and other appliances to meet the necessities of vessels passing through the same from ocean to ocean.