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Home > Category Index for Science Quotations > Category Index C > Category: Chloroform

Chloroform Quotes (5 quotes)

From common salt are obtained chemically as primary derivatives chlorine—both a war gas and a means of purifying water; and 'caustic soda.' … [O]n the chlorine side there is obtained chloride of lime, (a bleaching powder and a disinfectant), chloroform (an anesthetic), phosgene (a frightful ware gas), chloroacetophenone (another war gas), and an indigo and a yellow dye. [O]n the soda side we get metallic sodium, from which are derived sodium cyanide (a disinfectant), two medicines with [long] names, another war gas, and a beautiful violet dye. Thus, from a healthful, preservative condiment come things useful and hurtful—according to the intent or purpose.
Anonymous
The Homiletic Review, Vol. 83-84 (1922), Vol. 83, 209.
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I heard … xenon was a good anesthesia. … I thought, “How can xenon, which doesn’t form any chemical compounds, serve as a general anesthetic? … I lay awake at night for a few minutes before going to sleep, and during the next couple of weeks each night I would think, “…how do anesthetic agents work?" Then I forgot to do it after a while, but I’d trained my unconscious mind to keep this question alive and to call [it] to my consciousness whenever a new idea turned up…. So seven years went by. [One day I] put my feet up on the desk and started reading my mail, and here was a letter from George Jeffrey … an x-ray crystallographer, on his determination of the structure of a hydrate crystal. Immediately I sat up, took my feet off the desk, and said, “I understand anesthesia!” … I spent a year [and] determined the structure of chloroform hydrate, and then I wrote my paper published in June of 1961.
Interview with George B. Kauffman and Laurie M. Kauffman, in 'Linus Pauling: Reflections', American Scientist (Nov-Dec 1994), 82, No. 6, 522-523.
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It is best to attenuate the virulence of our adversaries with the chloroform of courtesy and flattery, much as bacteriologists disarm a pathogen by converting it into a vaccine.
In Charlas de Café: pensamientos, anécdotas y confidencias (1920, 1967), 32. (Café Chats: Thoughts, Anecdotes and Confidences). As translated in Peter McDonald (ed.) Oxford Dictionary of Medical Quotations (2004), 83. From the original Spanish, “Cuando no se ha nacido rico y es fuerza, por tanto, luchar por la existencia, la más hábil y piadosa conducta consiste en adormecer y atenuar la toxicidad de nuestros émulos y adversarios con el cloroformo de la cortesía y del halago. Procedamos como el bacteriólogo que, en la imposibilidad de aniquilar al microbio, opta por embolarlo, es decir, por convertirlo en saludable vacuna.” A more literal translation attempted by Webmaster using Google Translate is “When you are not born rich and mighty, thus, struggle for existence, the most shrewd and pious behavior is to calm and reduce the toxicity of our rivals and adversaries with the chloroform of politeness and flattery. Proceed as the bacteriologist who, unable to kill the microbe, opt for embolization (?), ie, by converting it into a healthy vaccine.”
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Of the various anesthetics which have been introduced for surgical use, only two deserve to be considered, and in order of preference they are ether and chloroform. In general, there is no comparison between these agents. Ether is so much safer than chloroform that the latter is fast disappearing in practice. In the present rapid progress of science it can not but be a short while until chloroform will only he employed in a very limited number of cases. The estimated death-rate after ether is 1 in 20,000, in chloroform 1 in 3,000. All of the objections to ether by the advocates of chloroform narcosis—namely, its slowness of action, irritation of the respiratory tract, nausea and vomiting, inflammability, extra quantity required, etc.—fade into insignificance when brought face to face with the fact that about seven lives are sacrificed by chloroform to one by ether.
In A Text-Book on Surgery: General, Operative, and Mechanical (1887), 24.
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When the simplest compounds of this element are considered (marsh gas, chloride of carbon, chloroform, carbonic acid, phosgene, sulphide of carbon, hydrocyanic acid, etc.) it is seen that the quantity of carbon which chemists have recognised as the smallest possible, that is, as an atom, always unites with 4 atoms of a monatomic or with two atoms of a diatomic element; that in general, the sum of the chemical units of the elements united with one atom of carbon is 4. This leads us to the view that carbon is tetratomic or tetrabasic. In the cases of substances which contain several atoms of carbon, it must be assumed that at least some of the atoms are in some way held in the compound by the affinity of carbon, and that the carbon atoms attach themselves to one another, whereby a part of the affinity of the one is naturally engaged with an equal part of the affinity of the other. The simplest and therefore the most probable case of such an association of carbon atoms is that in which one affinity unit of one is bound by one of the other. Of the 2 x 4 affinity units of the two carbon atoms, two are used up in holding the atoms together, and six remain over, which can be bound by atom)' of other elements.
'Ueber die Konstitution und die Metamorphosen der chemischen Verbindungen', Annalen (1858) 5, 106. Trans. in J. R. Partington, A History of Chemistry (1972), Vol. 4, 536.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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