Reactant Quotes (2 quotes)
It was obvious—to me at any rate—that the answer was to why an enzyme is able to speed up a chemical reaction by as much as 10 million times. It had to do this by lowering the energy of activation—the energy of forming the activated complex. It could do this by forming strong bonds with the activated complex, but only weak bonds with the reactants or products.
The whole art of making experiments in chemistry is founded on the principle: we must always suppose an exact equality or equation between the principles of the body examined and those of the products of its analysis.