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Baron Clemens von Pirquet
(12 May 1874 - 28 Feb 1929)
Austrian physician and immunologist who originated Pirquet's test (1907), a landmark diagnostic for tuberculosis, made by the application of tuberculin to a superficial abrasion of the skin of the arm.
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Science Quotes by Baron Clemens von Pirquet (2 quotes)
A drop of old tuberculin, which is an extract of tubercle bacilli, is put on the skin and then a small superficial scarification is made by turning, with some pressure, a vaccination lancet on the surface of the skin. The next day only those individuals show an inflammatory reaction at the point of vaccination who have already been infected with tuberculosis, whereas the healthy individuals show no reaction at all. Every time we find a positive reaction, we can say with certainty that the child is tuberculous.
— Baron Clemens von Pirquet
'The Relation of Tuberculosis to Infant Mortality', read at the third mid-year meeting of the American Academy of Medicine, New Haven, Conn, (4 Nov 1909). In Bulletin of the American Academy of Medicine (1910), 11, 75.
The conception that antibodies, which should protect against disease, are also responsible for the disease, sounds at first absurd. This has as its basis the fact that we are accustomed to see in disease only the harm done to the organism and to see in the antibodies solely antitoxic [protective] substances. One forgets too easily that the disease represents only a stage in the development of immunity, and that the organism often attains the advantage of immunity only by means of disease. ... Serum sickness represents, so to speak, an unnatural (artificial) form of disease.
— Baron Clemens von Pirquet
C. von Pirquet and B. Schick, Die Serumkrankheit (1906), trans B. Schick, Serum Sickness (1951), 119-20.
Quotes by others about Baron Clemens von Pirquet (1)
Professor von Pirquet has come to this country exactly at the right time to aid us. He has shown us how to detect tuberculosis before it has become so developed as to be contagious and has so taken hold of the individual as to be recognized by any other means. In thousands of cases I for my part am unable to detect tuberculosis in infancy or early childhood without the aid of the tuberculin test which Prof. von Pirquet has shown to be the best. He has taught us how by tubercular skin tests, to detect it. ... What Dr. von Pirquet has done already will make his name go down to posterity as one of the great reformers in tuberculin tests and as one who has done an immense amount of good to humanity. The skin test in twenty-four hours will show you whether the case is tubercular.
Discussion on 'The Relation of Tuberculosis to Infant Mortality', read at the third mid-year meeting of the American Academy of Medicine, New Haven, Conn, (4 Nov 1909). In Bulletin of the American Academy of Medicine (1910), 11, 78.
See also:
- 12 May - short biography, births, deaths and events on date of Pirquet's birth.
In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion.
(1987) -- 
