A scientist lives with all of reality. There is nothing better. To know reality is to accept it and eventually to love it.

A vast number, perhaps the numerical majority, of animal forms cannot be shown unequivocally to possess mind.

As followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.

Biology cannot go far in its subject without being met by mind.

If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (–), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.

In the training and in the exercise of medicine a remoteness abides between the field of neurology and that of mental health, psychiatry. It is sometimes blamed to prejudice on the part of the one side or the other. It is both more grave and less grave than that. It has a reasonable basis. It is rooted in the energy-mind problem. Physiology has not enough to offer about the brain in relation to the mind to lend the psychiatrist much help.

Natural knowledge has not forgone emotion. It has simply taken for itself new ground of emotion, under impulsion from and in sacrifice to that one of its 'values', Truth.

scientist is a ... learned child. Others must outgrow it. Scientists can stay that way all their life.

That our being should consist of two fundamental elements [physical and psychical] offers I suppose no greater inherent improbability than that it should rest on one only.

The brain is waking and with it the mind is returning. It is as if the Milky Way entered upon some cosmic dance. Swiftly the head-mass becomes an enchanted loom where millions of flashing shuttles weave a dissolving pattern, always a meaningful pattern though never an abiding one.

The brain seems a thoroughfare for nerve-action passing its way to the motor animal. It has been remarked that Life's aim is an act not a thought. To-day the dictum must be modified to admit that, often, to refrain from an act is no less an act than to commit one, because inhibition is coequally with excitation a nervous activity.

The role of inhibition in the working of the central nervous system has proved to be more and more extensive and more and more fundamental as experiment has advanced in examining it. Reflex inhibition can no longer be regarded merely as a factor specially developed for dealing with the antagonism of opponent muscles acting at various hinge-joints. Its role as a coordinative factor comprises that, and goes beyond that. In the working of the central nervous machinery inhibition seems as ubiquitous and as frequent as is excitation itself. The whole quantitative grading of the operations of the spinal cord and brain appears to rest upon mutual interaction between the two central processes 'excitation' and 'inhibition', the one no less important than the other. For example, no operation can be more important as a basis of coordination for a motor act than adjustment of the quantity of contraction, e.g. of the number of motor units employed and the intensity of their individual tetanic activity. This now appears as the outcome of nice co-adjustment of excitation and inhibition upon each of all the individual units which cooperate in the act.

The terminal path may, to distinguish it from internuncial common paths, be called the final common path. The motor nerve to a muscle is a collection of such final common paths.

This integrative action in virtue of which the nervous system unifies from separate organs an animal possessing solidarity, an individual, is the problem before us.

With the nervous system intact the reactions of the various parts of that system, the 'simple reflexes', are ever combined into great unitary harmonies, actions which in their sequence one upon another constitute in their continuity what may be termed the 'behaviour'.