… just as the astronomer, the physicist, the geologist, or other student of objective science looks about in the world of sense, so, not metaphorically speaking but literally, the mind of the mathematician goes forth in the universe of logic in quest of the things that are there; exploring the heights and depths for facts—ideas, classes, relationships, implications, and the rest; observing the minute and elusive with the powerful microscope of his Infinitesimal Analysis; observing the elusive and vast with the limitless telescope of his Calculus of the Infinite; making guesses regarding the order and internal harmony of the data observed and collocated; testing the hypotheses, not merely by the complete induction peculiar to mathematics, but, like his colleagues of the outer world, resorting also to experimental tests and incomplete induction; frequently finding it necessary, in view of unforeseen disclosures, to abandon one hopeful hypothesis or to transform it by retrenchment or by enlargement:—thus, in his own domain, matching, point for point, the processes, methods and experience familiar to the devotee of natural science.

Astronomy is one of the sublimest fields of human investigation. The mind that grasps its facts and principles receives something of the enlargement and grandeur belonging to the science itself. It is a quickener of devotion.

Chemical research conducts to the knowledge of philosophical truth, and forms the mind to philosophical enlargement and accuracy of thought, more happily than almost any other species of investigation in which the human intellect can be employed.

Diseased nature oftentimes breaks forth
In strange eruptions: oft the teeming earth
Is with a kind of colic pinch’d and vex’d
By the imprisoning of unruly wind
Within her womb; which, for enlargement striving,
Shakes the old beldam earth, and topples down
Steeples and moss-grown towers.

Every discovery, every enlargement of the understanding, begins as an imaginative preconception of what the truth might be. The imaginative preconception—a “hypothesis”—arises by a process as easy or as difficult to understand as any other creative act of mind; it is a brainwave, an inspired guess, a product of a blaze of insight. It comes anyway from within and cannot be achieved by the exercise of any known calculus of discovery.

It is probable that the scheme of physics will be enlarged so as to embrace the behaviour of living organisms under the influence of life and mind. Biology and psychology are not alien sciences; their operations are not solely mechanical, nor can they be formulated by physics as it is today; but they belong to a physical universe, and their mode of action ought to be capable of being formulated in terms of an enlarged physics in the future, in which the ether will take a predominant place. On the other hand it may be thought that those entities cannot be brought to book so easily, and that they will always elude our ken. If so, there will be a dualism in the universe, which posterity will find staggering, but that will not alter the facts.

The end of our foundation [Salomon's House in the New Atlantis] is the knowledge of Causes and the secret motions of things; and the enlarging of the bounds of Human Empire, to the effecting of all things possible.

There is no supernatural, there is only nature. Nature alone exists and contains all. All is. There is the part of nature that we perceive, and the part of nature that we do not perceive. … If you abandon these facts, beware; charlatans will light upon them, also the imbecile. There is no mean: science, or ignorance. If science does not want these facts, ignorance will take them up. You have refused to enlarge human intelligence, you augment human stupidity. When Laplace withdraws Cagliostro appears.