An ignorant or half-informed teacher may present science as an accumulation of unconnected facts. … To teach in that fashion is like going to the tree of science with its glorious fruit in order to pick up a handful of the dry fallen leaves from the ground.

I think that intelligence does not emerge from a handful of very beautiful principles—like physics. It emerges from perhaps a hundred fundamentally different kinds of mechanisms that have to interact just right. So, even if it took only four years to understand them, it might take four hundred years to unscramble the whole thing.

If it be true, that some Chymists have now and then converted Lead into Gold, it was by just such a hazard, as if a man should let fall a handful of sand upon a table and the particles of it should be so ranged that we could read distinctly on it a whole page of Virgil’s Ænead.

If our intention had been merely to bring back a handful of soil and rocks from the lunar gravel pit and then forget the whole thing, we would certainly be history's biggest fools. But that is not our intention now—it never will be. What we are seeking in tomorrow's [Apollo 11] trip is indeed that key to our future on earth. We are expanding the mind of man. We are extending this God-given brain and these God-given hands to their outermost limits and in so doing all mankind will benefit. All mankind will reap the harvest…. What we will have attained when Neil Armstrong steps down upon the moon is a completely new step in the evolution of man.

In 1944 Erwin Schroedinger, stimulated intellectually by Max Delbruck, published a little book called What is life? It was an inspiration to the first of the molecular biologists, and has been, along with Delbruck himself, credited for directing the research during the next decade that solved the mystery of how 'like begat like.' Max was awarded this Prize in 1969, and rejoicing in it, he also lamented that the work for which he was honored before all the peoples of the world was not something which he felt he could share with more than a handful. Samuel Beckett's contributions to literature, being honored at the same time, seemed to Max somehow universally accessible to anyone. But not his. In his lecture here Max imagined his imprisonment in an ivory tower of science.

Men can construct a science with very few instruments, or with very plain instruments; but no one on earth could construct a science with unreliable instruments. A man might work out the whole of mathematics with a handful of pebbles, but not with a handful of clay which was always falling apart into new fragments, and falling together into new combinations. A man might measure heaven and earth with a reed, but not with a growing reed.

Most people regard scientists as explorers … Imagine a handful of people shipwrecked on a strange island and setting out to explore it. One of them cuts a solitary path through the jungle, going on and on until he is exhausted or lost or both. He eventually returns to his companions, and they listen to him with goggling eyes as he describes what he saw; what he fell into, and what bit him. After a rest he demands more supplies and sets off again to explore the unknown. Many of his companions will be doing the same, each choosing his own direction and pursuing his pioneering path.

Occurrences that other men would have noted only with the most casual interest became for Whitney exciting opportunities to experiment. Once he became disturbed by a scientist's seemingly endless pursuit of irrelevant details in the course of an experiment, and criticized this as being as pointless as grabbing beans out of a pot, recording the numbers, and then analyzing the results. Later that day, after he had gone home, his simile began to intrigue him, and he asked himself whether it would really be pointless to count beans gathered in such a random manner. Another man might well have dismissed this as an idle fancy, but to Whitney an opportunity to conduct an experiment was not to be overlooked. Accordingly, he set a pot of beans beside his bed, and for several days each night before retiring he would take as many beans as he could grasp in one hand and make a note of how many were in the handful. After several days had passed he was intrigued to find that the results were not as unrewarding as he had expected. He found that each handful contained more beans than the one before, indicating that with practice he was learning to grasp more and more beans. “This might be called research in morphology, the science of animal structure,” he mused. “My hand was becoming webbed … so I said to myself: never label a real experiment useless, it may reveal something unthought of but worth knowing.”

One gram of moss from the forest floor, a piece about the size of a muffin, would harbor 150,000 protozoa, 132,000 tardigrades, 3,000 springtails, 800 rotifers, 500 nematodes, 400 mites, and 200 fly larvae. These numbers tell us something about the astounding quantity of life in a handful of moss.

Philosophers no longer write for the intelligent, only for their fellow professionals. The few thousand academic philosophers in the world do not stint themselves: they maintain more than seventy learned journals. But in the handful that cover more than one subdivision of philosophy, any given philosopher can hardly follow more than one or two articles in each issue. This hermetic condition is attributed to “technical problems” in the subject. Since William James, Russell, and Whitehead, philosophy, like history, has been confiscated by scholarship and locked away from the contamination of general use.

Remarkably, only a handful of fundamental physical principles are sufficient to summarize most of modern physics.

See with what entire freedom the whaleman takes his handful of lamps—often but old bottles and vials, though. … He burns, too, the purest of oil. … It is sweet as early grass butter in April. He goes and hunts for his oil, so as to be sure of its freshness and genuineness, even as the traveler on the prairie hunts up his own supper of game.

To the east was our giant neighbor Makalu, unexplored and unclimbed, and even on top of Everest the mountaineering instinct was sufficient strong to cause me to spend some moments conjecturing as to whether a route up that mountain might not exist. Far away across the clouds the great bulk of Kangchenjunga loomed on the horizon. To the west, Cho Oyu, our old adversary from 1952, dominated the scene and we could see the great unexplored ranges of Nepal stretching off into the distance. The most important photograph, I felt, was a shot down the north ridge, showing the North Col and the old route that had been made famous by the struggles of those great climbers of the 1920s and 1930s. I had little hope of the results being particularly successful, as I had a lot of difficulty in holding the camera steady in my clumsy gloves, but I felt that they would at least serve as a record. After some ten minutes of this, I realized that I was becoming rather clumsy-fingered and slow-moving, so I quickly replaced my oxygen set and experience once more the stimulating effect of even a few liters of oxygen. Meanwhile, Tenzing had made a little hole in the snow and in it he placed small articles of food – a bar of chocolate, a packet of biscuits and a handful of lollies. Small offerings, indeed, but at least a token gifts to the gods that all devoted Buddhists believe have their home on this lofty summit. While we were together on the South Col two days before, Hunt had given me a small crucifix that he had asked me to take to the top. I, too, made a hole in the snow and placed the crucifix beside Tenzing’s gifts.

When you can dump a load of bricks on a corner lot, and let me watch them arrange themselves into a house — when you can empty a handful of springs and wheels and screws on my desk, and let me see them gather themselves together into a watch — it will be easier for me to believe that all these thousands of worlds could have been created, balanced, and set to moving in their separate orbits, all without any directing intelligence at all.