A l’aide de ces sciences expérimentales actives, l’homme devient un inventeur de phénomènes, un véritable contremaître de la création; et l'on ne saurait, sous ce rapport, assigner de limites à la puissance qu’il peut acquérir sur la nature, par les progrès futurs des sciences expérimentales
With the aid of these active experimental sciences man becomes an inventor of phenomena, a real foreman of creation; and under this head we cannot set limits to the power that he may gain over nature through future progress of the experimental sciences.

Neue Phaenomena zu erklären, dieses macht meine Sorgen aus, und wie froh ist der Forscher, wenn er das so fleissig Gesuche findet, eine Ergötzung wobei das Herz lacht.
To explain new phenomena, that is my task; and how happy is the scientist when he finds what he so diligently sought, a pleasure that gladdens the heart.

A man can do his best only by confidently seeking (and perpetually missing) an unattainable perfection.

A man of science rises ever, in seeking truth; and if he never finds it in its wholeness, he discovers nevertheless very significant fragments; and these fragments of universal truth are precisely what constitutes science.

All of our experience indicates that life can manifest itself only in a concrete form, and that it is bound to certain substantial loci. These loci are cells and cell formations. But we are far from seeking the last and highest level of understanding in the morphology of these loci of life. Anatomy does not exclude physiology, but physiology certainly presupposes anatomy. The phenomena that the physiologist investigates occur in special organs with quite characteristic anatomical arrangements; the various morphological parts disclosed by the anatomist are the bearers of properties or, if you will, of forces probed by the physiologist; when the physiologist has established a law, whether through physical or chemical investigation, the anatomist can still proudly state: This is the structure in which the law becomes manifest.

An infinity of these tiny animals defoliate our plants, our trees, our fruits... they attack our houses, our fabrics, our furniture, our clothing, our furs ... He who in studying all the different species of insects that are injurious to us, would seek means of preventing them from harming us, would seek to cause them to perish, proposes for his goal important tasks indeed.

Data isn't information. ... Information, unlike data, is useful. While there’s a gulf between data and information, there’s a wide ocean between information and knowledge. What turns the gears in our brains isn't information, but ideas, inventions, and inspiration. Knowledge—not information—implies understanding. And beyond knowledge lies what we should be seeking: wisdom.

For myself, I found that I was fitted for nothing so well as for the study of Truth; as having a mind nimble and versatile enough to catch the resemblances of things (which is the chief point) , and at the same time steady enough to fix and distinguish their subtler differences; as being gifted by nature with desire to seek, patience to doubt, fondness to meditate, slowness to assert, readiness to reconsider, carefulness to dispose and set in order; and as being a man that neither affects what is new nor admires what is old, and that hates every kind of imposture. So I thought my nature had a kind of familiarity and relationship with Truth.

I am now convinced that we have recently become possessed of experimental evidence of the discrete or grained nature of matter, which the atomic hypothesis sought in vain for hundreds and thousands of years. The isolation and counting of gaseous ions, on the one hand, which have crowned with success the long and brilliant researches of J.J. Thomson, and, on the other, agreement of the Brownian movement with the requirements of the kinetic hypothesis, established by many investigators and most conclusively by J. Perrin, justify the most cautious scientist in now speaking of the experimental proof of the atomic nature of matter, The atomic hypothesis is thus raised to the position of a scientifically well-founded theory, and can claim a place in a text-book intended for use as an introduction to the present state of our knowledge of General Chemistry.

I sought excitement and, taking chances, I was all ready to fail in order to achieve something large.

If our intention had been merely to bring back a handful of soil and rocks from the lunar gravel pit and then forget the whole thing, we would certainly be history's biggest fools. But that is not our intention now—it never will be. What we are seeking in tomorrow's [Apollo 11] trip is indeed that key to our future on earth. We are expanding the mind of man. We are extending this God-given brain and these God-given hands to their outermost limits and in so doing all mankind will benefit. All mankind will reap the harvest…. What we will have attained when Neil Armstrong steps down upon the moon is a completely new step in the evolution of man.

If we seek for the simplest arrangement, which would enable it [the eye] to receive and discriminate the impressions of the different parts of the spectrum, we may suppose three distinct sensations only to be excited by the rays of the three principal pure colours, falling on any given point of the retina, the red, the green, and the violet; while the rays occupying the intermediate spaces are capable of producing mixed sensations, the yellow those which belong to the red and green, and the blue those which belong to the green and violet.

It has often been said that, to make discoveries, one must be ignorant. This opinion, mistaken in itself, nevertheless conceals a truth. It means that it is better to know nothing than to keep in mind fixed ideas based on theories whose confirmation we constantly seek, neglecting meanwhile everything that fails to agree with them.

It is not the possession of truth, but the success which attends the seeking after it, that enriches the seeker and brings happiness to him.

Men who believe too firmly in their theories, do not believe enough in the theories of others. So … these despisers of their fellows … make experiments only to destroy a theory, instead of to seek the truth.

Nature is disordered, powerful and chaotic, and through fear of the chaos we impose system on it. We abhor complexity, and seek to simplify things whenever we can by whatever means we have at hand. We need to have an overall explanation of what the universe is and how it functions. In order to achieve this overall view we develop explanatory theories which will give structure to natural phenomena: we classify nature into a coherent system which appears to do what we say it does.

Pure mathematics is, in its way, the poetry of logical ideas. One seeks the most general ideas of operation which will bring together in simple, logical and unified form the largest possible circle of formal relationships. In this effort toward logical beauty spiritual formulas are discovered necessary for the deeper penetration into the laws of nature.

Science knows no politics. Are we in this frenzy of [the Depression] economy, brought about by those who control the wealth of this country, seeking to put a barrier on science and research for the paltry sum of $39,113 out of an appropriation of $100,000,000?

Science today will either have to seek a source of inspiration higher than itself or perish.

Scientific research is one of the most exciting and rewarding of occupations. It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge. It should appeal to those with a good sense of adventure.

Several very eminent living paleontologists frequently emphasise the abruptness of some of the major changes that have occurred, and seek for an external cause. This is a heady wine and has intoxicated palaeontologists since the days when they could blame it all on Noah's flood. In fact, books are still being published by the lunatic fringe with the same explanation. In case this book should be read by some fundamentalist searching for straws to prop up his prejudices, let me state categorically that all my experience (such as it is) has led me to an unqualified acceptance of evolution by natural selection as a sufficient explanation for what I have seen in the fossil record

The meaning that we are seeking in evolution is its meaning to us, to man. The ethics of evolution must be human ethics. It is one of the many unique qualities of man, the new sort of animal, that he is the only ethical animal. The ethical need and its fulfillment are also products of evolution, but they have been produced in man alone.

The presence of those seeking the truth is infinitely to be preferred to the presence of those who think they’ve found it.

The true worth of an experimenter consists in his pursuing not only what he seeks in his experiment, but also what he did not seek.

There are, and can be, but these two ways of seeking truth; the former, the anticipatory, is the one now in use; the latter is the true but yet untried path.

This relation logical implication is probably the most rigorous and powerful of all the intellectual enterprises of man. From a properly selected set of the vast number of prepositional functions a set can be selected from which an infinitude of prepositional functions can be implied. In this sense all postulational thinking is mathematics. It can be shown that doctrines in the sciences, natural and social, in history, in jurisprudence and in ethics are constructed on the postulational thinking scheme and to that extent are mathematical. Together the proper enterprise of Science and the enterprise of Mathematics embrace the whole knowledge-seeking activity of mankind, whereby “knowledge” is meant the kind of knowledge that admits of being made articulate in the form of propositions.

To use Newton’s words, our efforts up till this moment have but turned over a pebble or shell here and there on the beach, with only a forlorn hope that under one of them was the gem we were seeking. Now we have the sieve, the minds, the hands, the time, and, particularly, the dedication to find those gems—no matter in which favorite hiding place the children of distant worlds have placed them.
[Co-author with Dava Sobel.]

Truly the gods have not from the beginning revealed all things to mortals, but by long seeking, mortals discover what is better.

We do not ask what hope of gain makes a little bird warble, since we know that it takes delight in singing because it is for that very singing that the bird was made, so there is no need to ask why the human mind undertakes such toil in seeking out these secrets of the heavens. ... And just as other animals, and the human body, are sustained by food and drink, so the very spirit of Man, which is something distinct from Man, is nourished, is increased, and in a sense grows up on this diet of knowledge, and is more like the dead than the living if it is touched by no desire for these things.

We should seek the greatest value of our action.
[Answer to question: So here we are. What should we do?]

When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. … Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.