I must confess, I am dreading today’s elections, … because no matter what the outcome, our government will still be a giant bonfire of partisanship. It is ironic since whenever I have met with our elected officials they are invariably thoughtful, well-meaning people. And yet collectively 90% of their effort seems to be focused on how to stick it to the other party.

It is a strange irony that the principles of science should seem to deny the necessary conviction of common sense.

It is an irony of fate that I myself have been the recipient of excessive admiration and reverence from my fellow-beings, through no fault, and no merit, of my own. The cause of this may well be the desire, unattainable for many, to understand the few ideas to which I have with my feeble powers attained through ceaseless struggle. I am quite aware that for any organisation to reach its goals, one man must do the thinking and directing and generally bear the responsibility. But the led must not be coerced, they must be able to choose their leader.

It is ironical that, in the very field in which Science has claimed superiority to Theology, for example—in the abandoning of dogma and the granting of absolute freedom to criticism—the positions are now reversed. Science will not tolerate criticism of special relativity, while Theology talks freely about the death of God, religionless Christianity, and so on.

It is one of the little ironies of our times that while the layman was being indoctrinated with the stereotype image of black holes as the ultimate cookie monsters, the professionals have been swinging round to the almost directly opposing view that black holes, like growing old, are really not so bad when you consider the alternative.

One of the ironies of volcanoes is that they tend to produce very fertile soils, and that tends to lure people to live around them.

The methods of science aren’t foolproof, but they are indefinitely perfectible. Just as important: there is a tradition of criticism that enforces improvement whenever and wherever flaws are discovered. The methods of science, like everything else under the sun, are themselves objects of scientific scrutiny, as method becomes methodology, the analysis of methods. Methodology in turn falls under the gaze of epistemology, the investigation of investigation itself—nothing is off limits to scientific questioning. The irony is that these fruits of scientific reflection, showing us the ineliminable smudges of imperfection, are sometimes used by those who are suspicious of science as their grounds for denying it a privileged status in the truth-seeking department—as if the institutions and practices they see competing with it were no worse off in these regards. But where are the examples of religious orthodoxy being simply abandoned in the face of irresistible evidence? Again and again in science, yesterday’s heresies have become today’s new orthodoxies. No religion exhibits that pattern in its history.

The Scientific Revolution turns us away from the older sayings to discover the lost authorization in Nature. What we have been through in these last four millennia is the slow inexorable profaning of our species. And in the last part of the second millennium A.D., that process is apparently becoming complete. It is the Great Human Irony of our noblest and greatest endeavor on this planet that in the quest for authorization, in our reading of the language of God in Nature, we should read there so clearly that we have been so mistaken.

There's a tendency these days to use science as a religion, and to see geneticists as the high priests of that religion. But, the irony is that, as geneticists know more, they get less and less confident.