This success permits us to hope that after thirty or forty years of observation on the new Planet [Neptune], we may employ it, in its turn, for the discovery of the one following it in its order of distances from the Sun. Thus, at least, we should unhappily soon fall among bodies invisible by reason of their immense distance, but whose orbits might yet be traced in a succession of ages, with the greatest exactness, by the theory of Secular Inequalities.
[Following the success of the confirmation of the existence of the planet Neptune, he considered the possibility of the discovery of a yet further planet.]

The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote. Nevertheless, it has been found that there are apparent exceptions to most of these laws, and this is particularly true when the observations are pushed to a limit, i.e., whenever the circumstances of experiment are such that extreme cases can be examined. Such examination almost surely leads, not to the overthrow of the law, but to the discovery of other facts and laws whose action produces the apparent exceptions. As instances of such discoveries, which are in most cases due to the increasing order of accuracy made possible by improvements in measuring instruments, may be mentioned: first, the departure of actual gases from the simple laws of the so-called perfect gas, one of the practical results being the liquefaction of air and all known gases; second, the discovery of the velocity of light by astronomical means, depending on the accuracy of telescopes and of astronomical clocks; third, the determination of distances of stars and the orbits of double stars, which depend on measurements of the order of accuracy of one-tenth of a second-an angle which may be represented as that which a pin's head subtends at a distance of a mile. But perhaps the most striking of such instances are the discovery of a new planet or observations of the small irregularities noticed by Leverrier in the motions of the planet Uranus, and the more recent brilliant discovery by Lord Rayleigh of a new element in the atmosphere through the minute but unexplained anomalies found in weighing a given volume of nitrogen. Many other instances might be cited, but these will suffice to justify the statement that “our future discoveries must be looked for in the sixth place of decimals.”

[Urbain Jean Joseph] Le Verrier—without leaving his study, without even looking at the sky—had found the unknown planet [Neptune] solely by mathematical calculation, and, as it were, touched it with the tip of his pen!

The entire annals of Observation probably do not elsewhere exhibit so extraordinary a verification of any theoretical conjecture adventured on by the human spirit!
[On the mathematical work by Urbain Le Verrier predicting the planet Neptune.]