Astonishing how great the precautions that are needed in these delicate experiments. Patience. Patience.

An immune system of enormous complexity is present in all vertebrate animals. When we place a population of lymphocytes from such an animal in appropriate tissue culture fluid, and when we add an antigen, the lymphocytes will produce specific antibody molecules, in the absence of any nerve cells. I find it astonishing that the immune system embodies a degree of complexity which suggests some more or less superficial though striking analogies with human language, and that this cognitive system has evolved and functions without assistance of the brain.

Development of Western science is based on two great achievements: the invention of the formal logical system (in Euclidean geometry) by the Greek philosophers, and the discovery of the possibility to find out causal relationships by systematic experiment (during the Renaissance). In my opinion, one has not to be astonished that the Chinese sages have not made these steps. The astonishing thing is that these discoveries were made at all.

Each nerve cell receives connections from other nerve cells at six sites called synapses. But here is an astonishing fact—there are about one million billion connections in the cortical sheet. If you were to count them, one connection (or synapse) per second, you would finish counting some thirty-two million years after you began. Another way of getting a feeling for the numbers of connections in this extraordinary structure is to consider that a large match-head’s worth of your brain contains about a billion connections. Notice that I only mention counting connections. If we consider how connections might be variously combined, the number would be hyperastronomical—on the order of ten followed by millions of zeros. (There are about ten followed by eighty zero’s worth of positively charged particles in the whole known universe!)

Four elements, hydrogen, carbon, oxygen and nitrogen, also provide an example of the astonishing togetherness of our universe. They make up the “organic” molecules that constitute living organisms on a planet, and the nuclei of these same elements interact to generate the light of its star. Then the organisms on the planet come to depend wholly on that starlight, as they must if life is to persist. So it is that all life on the Earth runs on sunlight. [Referring to photosynthesis]

I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this—never neglect an extraordinary appearance or happening. It may be—usually is, in fact—a false alarm that leads to nothing, but may on the other hand be the clue provided by fate to lead you to some important advance.

If a teacher is full of his subject, and can induce enthusiasm in his pupils; if his facts are concrete and naturally connected, the amount of material that an average child can assimilate without injury is as astonishing as is the little that will fag him if it is a trifle above or below or remote from him, or taught dully or incoherently.

If the great story of the last century was the conflict among various political ideologies—communism, fascism and democracy—then the great narrative of this century will be the changes wrought by astonishing scientific breakthroughs

In nature hybrid species are usually sterile, but in science the reverse is often true. Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.

In Pure Mathematics, where all the various truths are necessarily connected with each other, (being all necessarily connected with those hypotheses which are the principles of the science), an arrangement is beautiful in proportion as the principles are few; and what we admire perhaps chiefly in the science, is the astonishing variety of consequences which may be demonstrably deduced from so small a number of premises.

It is an astonishing feat of deciphering that we should have been able to infer an orderly scheme of natural knowledge from such indirect communication.

It is astonishing how much the word infinitely is misused: everything is infinitely more beautiful, infinitely better, etc. The concept must have something pleasing about it, or its misuse could not have become so general.

It is rather astonishing how little practical value scientific knowledge has for ordinary men, how dull and commonplace such of it as has value is, and how its value seems almost to vary inversely to its reputed utility.

It is, however, a most astonishing but incontestable fact, that the history of the evolution of man as yet constitutes no part of general education. Indeed, our so-called “educated classes” are to this day in total ignorance of the most important circumstances and the most remarkable phenomena which Anthropogeny has brought to light.

It was astonishing that for some considerable distance around the mould growth the staphococcal colonies were undergoing lysis. What had formerly been a well-grown colony was now a faint shadow of its former self...I was sufficiently interested to pursue the subject.
[Sep 1928, the first observation of penicillin. Lysis is the dissolution or destruction of cells.]

Mammals in general seem to live, at best, as long as it takes their hearts to count a billion. To this general rule, man himself is the most astonishing exception.

More than any other scientists we psychologists have to contend with the astonishing fact of resistance to the truth.

Nothing in education is so astonishing as the amount of ignorance it accumulates in the form of inert facts.

The Astonishing Hypothesis is that “You,” your joys and your sorrows, your memories and your ambitions, your sense of identity and free will, are in fact no more than the behaviour of a vast assembly of nerve cells and their associated molecules. As Lewis Carroll’s Alice might have phrased it: “You’re nothing but a pack of neurons.”

The notion that the “balance of nature” is delicately poised and easily upset is nonsense. Nature is extraordinarily tough and resilient, interlaced with checks and balances, with an astonishing capacity for recovering from disturbances in equilibrium. The formula for survival is not power; it is symbiosis.

The problem of modern democracy is not that the people have lost their power, but that they have lost their appreciation for the extraordinary power they wield. Consider one astonishing truth: Famine has never struck a democracy.

The reasoning of mathematicians is founded on certain and infallible principles. Every word they use conveys a determinate idea, and by accurate definitions they excite the same ideas in the mind of the reader that were in the mind of the writer. When they have defined the terms they intend to make use of, they premise a few axioms, or self-evident principles, that every one must assent to as soon as proposed. They then take for granted certain postulates, that no one can deny them, such as, that a right line may be drawn from any given point to another, and from these plain, simple principles they have raised most astonishing speculations, and proved the extent of the human mind to be more spacious and capacious than any other science.

The uniformity of the earth’s life, more astonishing than its diversity, is accountable by the high probability that we derived, originally, from some single cell, fertilized in a bolt of lightning as the earth cooled. It is from the progeny of this parent cell that we take our looks; we still share genes around, and the resemblance of the enzymes of grasses to those of whales is a family resemblance.

There is an astonishing imagination, even in the science of mathematics. … We repeat, there was far more imagination in the head of Archimedes than in that of Homer.

We know very little, and yet it is astonishing that we know so much, and still more astonishing that so little knowledge can give us so much power.

When the aggregate amount of solid matter transported by rivers in a given number of centuries from a large continent, shall be reduced to arithmetical computation, the result will appear most astonishing to those...not in the habit of reflecting how many of the mightiest of operations in nature are effected insensibly, without noise or disorder.

When we consider all that Hipparchus invented or perfected, and reflect upon the number of his works, and the mass of calculations which they imply, we must regard him as one of the most astonishing men of antiquity, and as the greatest of all in the sciences which are not purely speculative, and which require a combination of geometrical knowledge with a knowledge of phenomena, to be observed only by diligent attention and refined instruments.

While it is never safe to affirm that the future of Physical Science has no marvels in store even more astonishing than those of the past, it seems probable that most of the grand underlying principles have been firmly established and that further advances are to be sought chiefly in the rigorous application of these principles to all the phenomena which come under our notice.

While it is never safe to affirm that the future of Physical Science has no marvels in store even more astonishing than those of the past, it seems probable that most of the grand underlying principles have been firmly established, and that further advances are to be sought chiefly in the rigorous applications of these principles to all the phenomena which come under our notice. It is here that the science of measurement shows its importance—where the quantitative results are more to be desired than qualitative work. An eminent physicist has remarked that the future truths of Physical Science are to be looked for in the sixth place of decimals.