Histology is an exotic meal, but can be as repulsive as a dose of medicine for students who are obliged to study it, and little loved by doctors who have finished their study of it all too hastily. Taken compulsorily in large doses it is impossible to digest, but after repeated tastings in small draughts it becomes completely agreeable and even addictive. Whoever possesses a refined sensitivity for artistic manifestations will appreciate that, in the science of histology, there exists an inherent focus of aesthetic emotions.

If we range through the whole territory of nature, and endeavour to extract from each department the rich stores of knowledge and pleasure they respectively contain, we shall not find a more refined or purer source of amusement, or a more interesting and unfailing subject for recreation, than that which the observation and examination of the structure, affinities, and habits of plants and vegetables, afford.

If we take a survey of our own world … our portion in the immense system of creation, we find every part of it, the earth, the waters, and the air that surround it, filled, and as it were crouded with life, down from the largest animals that we know of to the smallest insects the naked eye can behold, and from thence to others still smaller, and totally invisible without the assistance of the microscope. Every tree, every plant, every leaf, serves not only as an habitation, but as a world to some numerous race, till animal existence becomes so exceedingly refined, that the effluvia of a blade of grass would be food for thousands.

Science starts with preconception, with the common culture, and with common sense. It moves on to observation, is marked by the discovery of paradox, and is then concerned with the correction of preconception. It moves then to use these corrections for the designing of further observation and for more refined experiment. And as it moves along this course the nature of the evidence and experience that nourish it becomes more and more unfamiliar; it is not just the language that is strange [to common culture].

The due cultivation of practical manual arts in a nation, has a greater tendency to polish, and humanize mankind, than mere speculative science, however refined and sublime it may be.

The great object of all knowledge is to enlarge and purify the soul, to fill the mind with noble contemplations, to furnish a refined pleasure, and to lead our feeble reason from the works of nature up to its great Author and Sustainer. Considering this as the ultimate end of science, no branch of it can surely claim precedence of Astronomy. No other science furnishes such a palpable embodiment of the abstractions which lie at the foundation of our intellectual system; the great ideas of time, and space, and extension, and magnitude, and number, and motion, and power. How grand the conception of the ages on ages required for several of the secular equations of the solar system; of distances from which the light of a fixed star would not reach us in twenty millions of years, of magnitudes compared with which the earth is but a foot-ball; of starry hosts—suns like our own—numberless as the sands on the shore; of worlds and systems shooting through the infinite spaces.

The philosopher may very justly be delighted with the extent of his views, the artificer with the readiness of his hands, but let the one remember that without mechanical performance, refined speculation is an empty dream, and the other that without theoretical reasoning, dexterity is little more than brute instinct.

When we consider all that Hipparchus invented or perfected, and reflect upon the number of his works, and the mass of calculations which they imply, we must regard him as one of the most astonishing men of antiquity, and as the greatest of all in the sciences which are not purely speculative, and which require a combination of geometrical knowledge with a knowledge of phenomena, to be observed only by diligent attention and refined instruments.