Gland Quotes (14 quotes)
Fertilization of mammalian eggs is followed by successive cell divisions and progressive differentiation, first into the early embryo and subsequently into all of the cell types that make up the adult animal. Transfer of a single nucleus at a specific stage of development, to an enucleated unfertilized egg, provided an opportunity to investigate whether cellular differentiation to that stage involved irreversible genetic modification. The first offspring to develop from a differentiated cell were born after nuclear transfer from an embryo-derived cell line that had been induced to became quiescent. Using the same procedure, we now report the birth of live lambs from three new cell populations established from adult mammary gland, fetus and embryo. The fact that a lamb was derived from an adult cell confirms that differentiation of that cell did not involve the irreversible modification of genetic material required far development to term. The birth of lambs from differentiated fetal and adult cells also reinforces previous speculation that by inducing donor cells to became quiescent it will be possible to obtain normal development from a wide variety of differentiated cells.
[Co-author of paper announcing the cloned sheep, ‘Dolly’.]
[Co-author of paper announcing the cloned sheep, ‘Dolly’.]
I heard Professor Cannon lecture last night, going partly on your account. His subject was a physiological substitute for war—which is international sports and I suppose motorcycle races—to encourage the secretion of the adrenal glands!
I propose to substitute the word 'autonomic'. The word implies a certain degree of independent action, but exercised under control of a higher power. The 'autonomic' nervous system means the nervous system of the glands and of the involuntary muscle; it governs the 'organic' functions of the body.
In order to form for one's self a just notion of the operations which result in the production of thought, it is necessary to conceive of the brain as a peculiar organ, specially designed for the production thereof, just as the stomach is designed to effect digestion, the liver to filter the bile, the parotids and the maxillary and sublingual glands to prepare the salivary juices.
No anatomist ever discovered a system of organization, calculated to produce pain and disease; or, in explaining the parts of the human body, ever said, this is to irritate; this is to inflame; this duct is to convey the gravel to the kidneys; this gland to secrete the humour which forms the gout: if by chance he come at a part of which he knows not the use, the most he can say is, that it is useless; no one ever suspects that it is put there to incommode, to annoy, or torment.
The ductless glands secrete among other things our moods, our aspirations, our philosophy of life.
The plexus called rectiform [rete mirabile] by anatomists, is the most wonderful of the bodies located in this region. It encircles the gland [the hypophysis] itself and extends far to the rear; for nearly the whole base of the encephalon has this plexus lying beneath it. It is not a simple network but [looks] as if you had taken several fisherman’s nets and superimposed them. It is characteristic of this net of Nature’s, however, that the meshes of one layer are always attached to those of another, and it is impossible to remove anyone of them alone; for, one after another, the rest follow the one you are removing, because they are all attached to one another successively.
The responsibility for maintaining the composition of the blood in respect to other constituents devolves largely upon the kidneys. It is no exaggeration to say that the composition of the blood is determined not by what the mouth ingests but by what the kidneys keep; they are the master chemists of our internal environment, which, so to speak, they synthesize in reverse. When, among other duties, they excrete the ashes of our body fires, or remove from the blood the infinite variety of foreign substances which are constantly being absorbed from our indiscriminate gastrointestinal tracts, these excretory operations are incidental to the major task of keeping our internal environment in an ideal, balanced state. Our glands, our muscles, our bones, our tendons, even our brains, are called upon to do only one kind of physiological work, while our kidneys are called upon to perform an innumerable variety of operations. Bones can break, muscles can atrophy, glands can loaf, even the brain can go to sleep, without immediately endangering our survival, but when the kidneys fail to manufacture the proper kind of blood neither bone, muscle, gland nor brain can carry on.
The theory of the lung as a gland has justified its existence and done excellent service in bringing forward facts, which shall survive any theoretical construction that has been or may hereafter be put upon them.
These changes—the more rapid pulse, the deeper breathing, the increase of sugar in the blood, the secretion from the adrenal glands—were very diverse and seemed unrelated. Then, one wakeful night, after a considerable collection of these changes had been disclosed, the idea flashed through my mind that they could be nicely integrated if conceived as bodily preparations for supreme effort in flight or in fighting. Further investigation added to the collection and confirmed the general scheme suggested by the hunch.
They say it doesn’t matter how long one washes one’s hands, because there will still be organisms in the sweat glands and hair follicles, so I rub my hands with Vaseline.
What we call man is a mechanism made up of … uncrystallized matter … all the colloid matter of his mechanism is concentrated in a countless number of small cells. … [T]hese cells [are] dwelling places, communes, a walled town within which are many citizens. ... [T]hese are the units of life and when they pass out into space man as we think we know him is dead, a mere machine from which the crew have left,so to speak. ... [T]hese units are endowed with great intelligence. They have memories, they must be divided into countless thousands of groups, most are workers, there are directing groups. Some are chemists, they manufacture the most complicated chemicals that are secreted by the glands.
Worry affects circulation, the heart, the glands, the whole nervous system, and profoundly affects the heart. I have never known a man who died from overwork, but many who died from doubt.
[After science lost] its mystical inspiration … man’s destiny was no longer determined from “above” by a super-human wisdom and will, but from “below” by the sub-human agencies of glands, genes, atoms, or waves of probability. … A puppet of the Gods is a tragic figure, a puppet suspended on his chromosomes is merely grotesque.