All change is relative. The universe is expanding relatively to our common material standards; our material standards are shrinking relatively to the size of the universe. The theory of the “expanding universe” might also be called the theory of the “shrinking atom”. …
:Let us then take the whole universe as our standard of constancy, and adopt the view of a cosmic being whose body is composed of intergalactic spaces and swells as they swell. Or rather we must now say it keeps the same size, for he will not admit that it is he who has changed. Watching us for a few thousand million years, he sees us shrinking; atoms, animals, planets, even the galaxies, all shrink alike; only the intergalactic spaces remain the same. The earth spirals round the sun in an ever-decreasing orbit. It would be absurd to treat its changing revolution as a constant unit of time. The cosmic being will naturally relate his units of length and time so that the velocity of light remains constant. Our years will then decrease in geometrical progression in the cosmic scale of time. On that scale man’s life is becoming briefer; his threescore years and ten are an ever-decreasing allowance. Owing to the property of geometrical progressions an infinite number of our years will add up to a finite cosmic time; so that what we should call the end of eternity is an ordinary finite date in the cosmic calendar. But on that date the universe has expanded to infinity in our reckoning, and we have shrunk to nothing in the reckoning of the cosmic being.
We walk the stage of life, performers of a drama for the benefit of the cosmic spectator. As the scenes proceed he notices that the actors are growing smaller and the action quicker. When the last act opens the curtain rises on midget actors rushing through their parts at frantic speed. Smaller and smaller. Faster and faster. One last microscopic blurr of intense agitation. And then nothing.

Available energy is energy which we can direct into any desired channel. Dissipated energy is energy which we cannot lay hold of and direct at pleasure, such as the energy of the confused agitation of molecules which we call heat. Now, confusion, like the correlative term order, is not a property of material things in themselves, but only in relation to the mind which perceives them. A memorandum-book does not, provided it is neatly written, appear confused to an illiterate person, or to the owner who understands it thoroughly, but to any other person able to read it appears to be inextricably confused. Similarly the notion of dissipated energy could not occur to a being who could not turn any of the energies of nature to his own account, or to one who could trace the motion of every molecule and seize it at the right moment. It is only to a being in the intermediate stage, who can lay hold of some forms of energy while others elude his grasp, that energy appears to be passing inevitably from the available to the dissipated state.

By the agitation of water and silt, and their gradual accumulation and consolidation... the rocks were formed gradually by the evolution of sediments in water.

Nicolle was one of those men who achieve their successes by long preliminary thought before an experiment is formulated, rather than by the frantic and often ill-conceived experimental activities that keep lesser men in ant-like agitation. Indeed. I have often thought of ants in observing the quantity output of ‘what-of-it’ literature from many laboratories. … Nicolle did relatively few and simple experiments. But every time he did one, it was the result of long hours of intellectual incubation during which all possible variants had been considered and were allowed for in the final tests. Then he went straight to the point, without wasted motion. That was the method of Pasteur, as it has been of all the really great men of our calling, whose simple, conclusive experiments are a joy to those able to appreciate them.

Science is a boundless adventure of the human spirit, its insights afford terror as well as beauty, and it will continue to agitate the world with new findings and new powers.

The diseases which are hard to cure in neighborhoods… are catarrh, hoarseness, coughs, pleurisy, consumption, spitting of blood, and all others that are cured not by lowering the system but by building it up. They are hard to cure, first, because they are originally due to chills; secondly, because the patient's system being already exhausted by disease, the air there, which is in constant agitation owing to winds and therefore deteriorated, takes all the sap of life out of their diseased bodies and leaves them more meager every day. On the other hand, a mild, thick air, without drafts and not constantly blowing back and forth, builds up their frames by its unwavering steadiness, and so strengthens and restores people who are afflicted with these diseases.

The longer I live, the more I am convinced that the apothecary is of more importance than Seneca; and that half the unhappiness in the world proceeds from little stoppages; from a duct choked up, from food pressing in the wrong place, from a vexed duodenum, or an agitated pylorus.

The wild gas, the fixed air is plainly broke loose: but we ought to suspend our judgments until the first effervescence is a little subsided, till the liquor is cleared, and until we see something deeper than the agitation of the troubled and frothy surface.
[About the “spirit of liberty;” alluding to Priestley’s Observations on Air]

There are, I believe, very few maxims in philosophy that have laid firmer hold upon the mind, than that air, meaning atmospherical air (free from various foreign matters, which were always supposed to be dissolved, and intermixed with it) is a simple elementary substance, indestructible, and unalterable, at least as much so as water is supposed to be. In the course of my enquiries, I was, however, soon satisfied that atmospherical air is not an unalterable thing; for that the phlogiston with which it becomes loaded from bodies burning in it, and animals breathing it, and various other chemical processes, so far alters and depraves it, as to render it altogether unfit for inflammation, respiration, and other purposes to which it is subservient; and I had discovered that agitation in water, the process of vegetation, and probably other natural processes, by taking out the superfluous phlogiston, restore it to its original purity.

To pick a hole–say in the 2nd law of Ω^cs, that if two things are in contact the hotter cannot take heat from the colder without external agency.
Now let A & B be two vessels divided by a diaphragm and let them contain elastic molecules in a state of agitation which strike each other and the sides. Let the number of particles be equal in A & B but let those in A have equal velocities, if oblique collisions occur between them their velocities will become unequal & I have shown that there will be velocities of all magnitudes in A and the same in B only the sum of the squares of the velocities is greater in A than in B.
When a molecule is reflected from the fixed diaphragm CD no work is lost or gained.
If the molecule instead of being reflected were allowed to go through a hole in CD no work would be lost or gained, only its energy would be transferred from the one vessel to the other.
Now conceive a finite being who knows the paths and velocities of all the molecules by simple inspection but who can do no work, except to open and close a hole in the diaphragm, by means of a slide without mass.
Let him first observe the molecules in A and when lie sees one coming the square of whose velocity is less than the mean sq. vel. of the molecules in B let him open a hole & let it go into B. Next let him watch for a molecule in B the square of whose velocity is greater than the mean sq. vel. in A and when it comes to the hole let him draw and slide & let it go into A, keeping the slide shut for all other molecules.
Then the number of molecules in A & B are the same as at first but the energy in A is increased and that in B diminished that is the hot system has got hotter and the cold colder & yet no work has been done, only the intelligence of a very observant and neat fingered being has been employed. Or in short if heat is the motion of finite portions of matter and if we can apply tools to such portions of matter so as to deal with them separately then we can take advantage of the different motion of different portions to restore a uniformly hot system to unequal temperatures or to motions of large masses. Only we can't, not being clever enough.