“I think you’re begging the question,” said Haydock, “and I can see looming ahead one of those terrible exercises in probability where six men have white hats and six men have black hats and you have to work it out by mathematics how likely it is that the hats will get mixed up and in what proportion. If you start thinking about things like that, you would go round the bend. Let me assure you of that!”

Doctors can do almost anything nowadays, can't they, unless they kill you while they're trying to cure you.

I continued to do arithmetic with my father, passing proudly through fractions to decimals. I eventually arrived at the point where so many cows ate so much grass, and tanks filled with water in so many hours I found it quite enthralling.

I don’t think necessity is the mother of invention. Invention, in my opinion, arises directly from idleness, possibly also from laziness—to save oneself trouble.

[Agatha Christie] is fond of quoting the witty wife who once said, “an archaeologist is the best husband any woman can have; the older she gets, the more interested he is in her.”

...the remark attributed to Mrs. [Agatha] Christie that 'the older you get, the more interesting you become to an archaeologist,' was the creation of some pundit whose neck Mrs. Christie would be glad to wring if he would care to identify himself—she neither made the remark nor does she consider it particularly complimentary or amusing.

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.