After we came out of the church, we stood talking for some time together of Bishop Berkeley’s ingenious sophistry to prove the non-existence of matter, and that every thing in the universe is merely ideal. I observed, that though we are satisfied his doctrine is not true, it is impossible to refute it. I never shall forget the alacrity with which Johnson answered, striking his foot with mighty force against a large stone, till he rebounded from it, “I refute it thus.”

Buffon, who, with all his theoretical ingenuity and extraordinary eloquence, I suspect had little actual information in the science on which he wrote so admirably For instance, he tells us that the cow sheds her horns every two years; a most palpable error. ... It is wonderful that Buffon who lived so much in the country at his noble seat should have fallen into such a blunder I suppose he has confounded the cow with the deer.

Dr. Johnson ... sometimes employed himself in chymistry, sometimes in watering and pruning a vine, and sometimes in small experiments, at which those who may smile, should recollect that there are moments which admit of being soothed only by trifles.

Even the taking of medicine serves to make time go on with less heaviness. I have a sort of genius for physic and always had great entertainment in observing the changes of the human body and the effects produced by diet, labor, rest, and physical operations.

He [Samuel Johnson] bid me always remember this, that after a system is well settled upon positive evidence, a few objections ought not to shake it. “The human mind is so limited that it cannot take in all parts of a subject; so that there may be objections raised against anything. There are objections against a plenum, and objections against a vacuum. Yet one of them must certainly be true.”

I complained to Mr. Johnson that I was much afflicted with melancholy, which was hereditary in our family. He said that he himself had been greatly distressed with it, and for that reason had been obliged to fly from study and meditation to the dissipating variety of life. He advised me to have constant occupation of mind, to take a great deal of exercise, and to live moderately; especially to shun drinking at night. “Melancholy people,” said he, are apt to fly to intemperance, which gives a momentary relief but sinks the soul much lower in misery.” He observed that laboring men who work much and live sparingly are seldom or never troubled with low spirits.

Johnson said that he could repeat a complete chapter of The Natural History of Iceland from the Danish of Horrebow, the whole of which was exactly thus: “There are no snakes to meet with throughout the whole island.

My Lord said that he who knew men only in this way [from history] was like one who had got the theory of anatomy perfectly, but who in practice would find himself very awkward and liable to mistakes. That he again who knew men by observation was like one who picked up anatomy by practice, but who like all empirics would for a long time be liable to gross errors.

The mind of a young man (his gallery I mean) is often furnished different ways. According to the scenes he is placed in, so are his pictures. They disappear, and he gets a new set in a moment. But as he grows up, he gets some substantial pieces which he always preserves, although he may alter his smaller paintings in a moment.

We often observe in lawyers, who as Quicquid agunt homines is the matter of law suits, are sometimes obliged to pick up a temporary knowledge of an art or science, of which they understood nothing till their brief was delivered, and appear to be much masters of it.

When Dr. Johnson felt, or fancied he felt, his fancy disordered, his constant recurrence was to the study of arithmetic.