All that Anatomie can doe is only to shew us the gross and sensible parts of the body, or the vapid and dead juices all which, after the most diligent search, will be noe more able to direct a physician how to cure a disease than how to make a man; for to remedy the defects of a part whose organicall constitution and that texture whereby it operates, he cannot possibly know, is alike hard, as to make a part which he knows not how is made. Now it is certaine and beyond controversy that nature performs all her operations on the body by parts so minute and insensible that I thinke noe body will ever hope or pretend, even by the assistance of glasses or any other intervention, to come to a sight of them, and to tell us what organicall texture or what kinde offerment (for whether it be done by one or both of these ways is yet a question and like to be soe always notwithstanding all the endeavours of the most accurate dissections) separate any part of the juices in any of the viscera, or tell us of what liquors the particles of these juices are, or if this could be donne (which it is never like to be) would it at all contribute to the cure of the diseases of those very parts which we so perfectly knew.

The maladies that affect the clerks aforesaid arise from three causes. First, constant sitting, secondly, the incessant movement of the the hand and always in the same direction, thirdly, the strain on the mind from the effort not to disfigure the books by errors or cause loss to their employers when they add, subtract, or do other sums in arithmetic. The diseases brought about by sitting constantly are easily understood; they are obstructions of the viscera, e.g. the liver and spleen, indigestion in the stomach, numbness of the legs, a considerable hindrance in the circulation of the blood, and an unhealthy habit.