[Creationists] make it sound as though a “theory” is something you dreamt up after being drunk all night.

Facts are a heap of bricks and timber. It is only a successful theory that can convert the heap into a stately mansion

In 1900 however, he [Planck] worked out the revolutionary quantum theory, a towering achievement which extended and improved the basic concepts of physics. It was so revolutionary, in fact, that almost no physicist, including Planck himself could bring himself to accept it. (Planck later said that the only way a revolutionary theory could be accepted was to wait until all the old scientists had died.)

It is a common rule in theoretical physics, one accepted by many physicists, that anything not forbidden by the basic laws of nature must take place.

Science is uncertain. Theories are subject to revision; observations are open to a variety of interpretations, and scientists quarrel amongst themselves. This is disillusioning for those untrained in the scientific method, who thus turn to the rigid certainty of the Bible instead. There is something comfortable about a view that allows for no deviation and that spares you the painful necessity of having to think.

The young specialist in English Lit, having quoted me, went on to lecture me severely on the fact that in every century people have thought they understood the Universe at last, and in every century they were proved to be wrong. It follows that the one thing we can say about our modern “knowledge” is that it is wrong.
The young man then quoted with approval what Socrates had said on learning that the Delphic oracle had proclaimed him the wisest man in Greece. “If I am the wisest man,” said Socrates, “it is because I alone know that I know nothing.” The implication was that I was very foolish because I was under the impression I knew a great deal.
Alas, none of this was new to me. (There is very little that is new to me; I wish my correspondents would realize this.) This particular theme was addressed to me a quarter of a century ago by John Campbell, who specialized in irritating me. He also told me that all theories are proven wrong in time.
My answer to him was, “John, when people thought the Earth was flat, they were wrong. When people thought the Earth was spherical, they were wrong. But if you think that thinking the Earth is spherical is just as wrong as thinking the Earth is flat, then your view is wronger than both of them put together.”

To test a perfect theory with imperfect instruments did not impress the Greek philosophers as a valid way to gain knowledge.