Accurate and minute measurement seems to the non-scientific imagination, a less lofty and dignified work than looking for something new. But nearly all the grandest discoveries of science have been but the rewards of accurate measurement and patient long-continued labour in the minute sifting of numerical results.

In physical science a first essential step in the direction of learning any subject is to find principles of numerical reckoning and practicable methods for measuring some quality connected with it. I often say that when you can measure what you are speaking about, and express it in numbers, you know something about it; but when you cannot measure it, when you cannot express it in numbers, your knowledge is of a meagre and unsatisfactory kind; it may be the beginning of knowledge, but you have scarcely in your thoughts advanced to the stage of science, whatever the matter may be.
Often seen quoted in a condensed form: If you cannot measure it, then it is not science.

There is nothing new to be discovered in physics now. All that remains is more and more precise measurement.

You, in this country [the USA], are subjected to the British insularity in weights and measures; you use the foot, inch and yard. I am obliged to use that system, but must apologize to you for doing so, because it is so inconvenient, and I hope Americans will do everything in their power to introduce the French metrical system. ... I look upon our English system as a wickedly, brain-destroying system of bondage under which we suffer. The reason why we continue to use it, is the imaginary difficulty of making a change, and nothing else; but I do not think in America that any such difficulty should stand in the way of adopting so splendidly useful a reform.