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Claude Bernard
(12 Jul 1813 - 10 Feb 1878)

French physiologist who helped establish the principles of experimentation in the life sciences. His Introduction to the Study of Experimental Medicine (1865) is a scientific classic.



A l’aide de ces sciences expérimentales actives, l’homme devient un inventeur de phénomènes, un véritable contremaître de la création; et l'on ne saurait, sous ce rapport, assigner de limites à la puissance qu’il peut acquérir sur la nature, par les progrès futurs des sciences expérimentales
With the aid of these active experimental sciences man becomes an inventor of phenomena, a real foreman of creation; and under this head we cannot set limits to the power that he may gain over nature through future progress of the experimental sciences.
— Claude Bernard
Original French text in Introduction à l'Étude de la Médecine Expérimentale (1898), 32. English version from An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 18.
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A man of science rises ever, in seeking truth; and if he never finds it in its wholeness, he discovers nevertheless very significant fragments; and these fragments of universal truth are precisely what constitutes science.
— Claude Bernard
From An Introduction to the Study of Experimental Medicine (1927, 1957), as translated by Henry Copley Greene (1927, 1957), 222. From the original French by Claude Bernard: “le savant monte toujours en cherchant la vérité, et s'il ne la trouve jamais tout entière, il en découvre néanmoins des fragments très-importants, et ce sont précisément ces fragments de la vérité générale qui constituent la science.” (1865), 389. A Google translation gives: “The scientist always rises by seeking the truth, and if he never finds it entirely, he nevertheless discovers very important fragments of it, and it is precisely these fragments of the general truth which constitute science.”
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A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.
— Claude Bernard
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 140-141.
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In the patient who succumbed, the cause of death was evidently something which was not found in the patient who recovered; this something we must determine, and then we can act on the phenomena or recognize and foresee them accurately. But not by statistics shall we succeed in this; never have statistics taught anything, and never can they teach anything about the nature of the phenomenon.
— Claude Bernard
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 138.
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Progress is achieved by exchanging our theories for new ones which go further than the old, until we find one based on a larger number of facts. … Theories are only hypotheses, verified by more or less numerous facts. Those verified by the most facts are the best, but even then they are never final, never to be absolutely believed.
— Claude Bernard
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 165.
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The better educated we are and the more acquired information we have, the better prepared shall we find our minds for making great and fruitful discoveries.
— Claude Bernard
In An Introduction to the Study of Experimental Medicine (1927, 1957), 38, as translated by Henry Copley Greene. From the original French by Claude Bernard: “Plus on est instruit, plus on possède de connaissances antérieures, mieux on aura l’esprit disposé pour faire des découvertes grandes et fécondes.” (1865), 67. A Google translation gives: “The more educated one is, the more prior knowledge one possesses, the better disposed one’s mind will be to make great and fruitful discoveries.”
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The experimenter who does not know what he is looking for will never understand what he finds.
— Claude Bernard
Attributed. Also seen as, “He who does not know what he is looking for will not lay hold of what he has found when he gets it.” If you know a primary source, perhaps in the original French, please contact Webmaster.
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When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. … Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
— Claude Bernard
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 213.
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See also:
  • 12 Jul - short biography, births, deaths and events on date of Bernard's birth.
  • Claude Bernard - context of quote The alchemists founded chemistry - Medium image (500 x 350 px)
  • Claude Bernard - context of quote “The alchemists founded chemistry” - Large image (800 x 600 px)
  • Claude Bernard - context of quote The experimenter - Medium image (500 x 350 px)
  • Claude Bernard - context of quote The experimenter - Large image (800 x 600 px)
  • Claude Bernard - context of quote Make experiments to … control our ideas - Medium image (500 x 350 px)
  • Claude Bernard - context of quote Make experiments to … control our ideas - Large image (800 x 600 px)

Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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