In order that the facts obtained by observation and experiment may be capable of being used in furtherance of our exact and solid knowledge, they must be apprehended and analysed according to some Conceptions which, applied for this purpose, give distinct and definite results, such as can be steadily taken hold of and reasoned from.

The framing of hypotheses is, for the enquirer after truth, not the end, but the beginning of his work. Each of his systems is invented, not that he may admire it and follow it into all its consistent consequences, but that he may make it the occasion of a course of active experiment and observation. And if the results of this process contradict his fundamental assumptions, however ingenious, however symmetrical, however elegant his system may be, he rejects it without hesitation. He allows no natural yearning for the offspring of his own mind to draw him aside from the higher duty of loyalty to his sovereign, Truth, to her he not only gives his affections and his wishes, but strenuous labour and scrupulous minuteness of attention.

The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.

The ideas which these sciences, Geometry, Theoretical Arithmetic and Algebra involve extend to all objects and changes which we observe in the external world; and hence the consideration of mathematical relations forms a large portion of many of the sciences which treat of the phenomena and laws of external nature, as Astronomy, Optics, and Mechanics. Such sciences are hence often termed Mixed Mathematics, the relations of space and number being, in these branches of knowledge, combined with principles collected from special observation; while Geometry, Algebra, and the like subjects, which involve no result of experience, are called Pure Mathematics.

To discover a Conception of the mind which will justly represent a train of observed facts is, in some measure, a process of conjecture, ... and the business of conjecture is commonly conducted by calling up before our minds several suppositions, selecting that one which most agrees with what we know of the observed facts. Hence he who has to discover the laws of nature may have to invent many suppositions before he hits upon the right one; and among the endowments which lead to his success, we must reckon that fertility of invention which ministers to him such imaginary schemes, till at last he finds the one which conforms to the true order of nature.

We cannot observe external things without some degree of Thought; nor can we reflect upon our Thoughts, without being influenced in the course of our reflection by the Things which we have observed.