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Home > Category Index for Science Quotations > Category Index L > Category: Laboratory

Laboratory Quotes (214 quotes)

Leon M. Lederman quote: During an intense period of lab work, the outside world vanishes and the obsession is total
Background: Michael Faraday in his laboratory at the Royal Institution. (source)

[As a youth, fiddling in my home laboratory] I discovered a formula for the frequency of a resonant circuit which was 2π x sqrt(LC) where L is the inductance and C the capacitance of the circuit. And there was π, and where was the circle? … I still don’t quite know where that circle is, where that π comes from.
From address to the National Science Teachers’ Association convention (Apr 1966), 'What Is Science?', collected in Richard Phillips Feynman and Jeffrey Robbins (ed.), The Pleasure of Finding Things Out: The Best Short Works of Richard P. Feynman (1999, 2005), 177.
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[Chemistry] laboratory work was my first challenge. ... I still carry the scars of my first discovery—that test-tubes are fragile.
Edward Teller with Judith L. Shoolery, Memoirs: A Twentieth-Century Journey in Science and Politics (2001), 42.
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[The surplus of basic knowledge of the atomic nucleus was] largely used up [during the war with the atomic bomb as the dividend.] We must, without further delay restore this surplus in preparation for the important peacetime job for the nucleus - power production. ... Many of the proposed applications of atomic power - even for interplanetary rockets - seem to be within the realm of possibility provided the economic factor is ruled out completely, and the doubtful physical and chemical factors are weighted heavily on the optimistic side. ... The development of economic atomic power is not a simple extrapolation of knowledge gained during the bomb work. It is a new and difficult project to reach a satisfactory answer. Needless to say, it is vital that the atomic policy legislation now being considered by the congress recognizes the essential nature of this peacetime job, and that it not only permits but encourages the cooperative research-engineering effort of industrial, government and university laboratories for the task. ... We must learn how to generate the still higher energy particles of the cosmic rays - up to 1,000,000,000 volts, for they will unlock new domains in the nucleus.
Addressing the American Institute of Electrical Engineering, in New York (24 Jan 1946). In Schenectady Gazette (25 Jan 1946),
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[When recording electrical impulses from a frog nerve-muscle preparation seemed to show a tiresomely oscillating electrical artefact—but only when the muscle was hanging unsupported.] The explanation suddenly dawned on me ... a muscle hanging under its own weight ought, if you come to think of it, to be sending sensory impulses up the nerves coming from the muscle spindles ... That particular day’s work, I think, had all the elements that one could wish for. The new apparatus seemed to be misbehaving very badly indeed, and I suddenly found it was behaving so well that it was opening up an entire new range of data ... it didn’t involve any particular hard work, or any particular intelligence on my part. It was just one of those things which sometimes happens in a laboratory if you stick apparatus together and see what results you get.
From 'Memorable experiences in research', Diabetes (1954), 3, 17-18. As cited in Alan McComa, Galvani's Spark: The Story of the Nerve Impulse (2011), 102-103.
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Clarke's First Law: When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.
'Hazards of Prophecy: The Failure of Imagination'. In the collection. Profiles of the Future: An Enquiry into the Limits of the Possible (1962, rev. 1973), 14.
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Drosophila melanogaster has been more extensively used in the study of genetics than any other organism, and the theory of heredity that is now generally accepted is based chiefly on the results obtained with this fly. … Not only has Drosophila been the most productive material for research in the subject, but it is now the standard object for laboratory instruction, and is used as such in many colleges and universities.
In The North American Species of Drosophila (1921), 12.
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Drosophila melanogaster Meigen…has in recent years come to be widely used as a laboratory animal, especially in the study of heredity. Its short life-cycle, great productivity, and the ease with which it may be bred have been chiefly responsible for making it so popular for this purpose.
In The North American Species of Drosophila (1921), 1.
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M.A. Rosanoff: Mr. Edison, please tell me what laboratory rules you want me to observe.
Edison: Hell! There ain’t no rules around here! We’re trying to accomplish somep’n.
In Martin André Rosanoff, 'Edison in His Laboratory', Harper’s Magazine (Sep 1932), 403.
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Sans laboratoires les savants sont des soldats sans armes
Without laboratories men of science are soldiers without arms.
In French, quoted as “cette phrase mémorable de Pasteur” (this memorable expression by Pasteur) in Bulletin de la Société de Gynécologie et d'Obstétrique de Paris (1923), 205. In French and English, as an epigraph, in The Wellcome Research Institution and the Affiliated Research Laboratories and Museums Founded by Sir Henry Wellcome (1932), 3.
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A first-rate laboratory is one in which mediocre scientists can produce outstanding work.
Quoted by M. G. K. Menon in his commemoration lecture on H. J. Bhabba, Royal Institution 1967.
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A German once has said of the Chemical Laboratory in Munich: “In diesem Hause stinkt es sehr, Dies kommt von Adolf Baeyer her.” [It stinks a lot in this house; this comes from Adolf Baeyer.]
From 'What Can the Modern Chemist Learn From the Old Alchemy?', Introductory Lecture (1917), delivered at Cornell University, written in German, translated by L.F. Audrieth, and published in Salts, Acids, and Bases: Electrolytes Stereochemistry (1929), 1, as Vol. 4 of the George Fisher Baker Non-Resident Lectureship in Chemistry at Cornell University. Translation of German part of above quote by Webmaster using Google Translate.
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A laboratory is only a place where one may better set up and control conditions.
Martin H. Fischer, Howard Fabing (ed.) and Ray Marr (ed.), Fischerisms (1944).
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Louis Agassiz quote: A laboratory of natural history is a sanctuary where nothing profane should be tolerated
A laboratory of natural history is a sanctuary where nothing profane should be tolerated. I feel less agony at improprieties in churches than in a scientific laboratory.
Lecture at a teaching laboratory on Penikese Island, Buzzard's Bay. Quoted from the lecture notes by David Starr Jordan, Science Sketches (1911), 147.
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A natural law regulates the advance of science. Where only observation can be made, the growth of knowledge creeps; where laboratory experiments can be carried on, knowledge leaps forward.
[Attributed, probably incorrectly]
Seen in various places, but Webmaster has found none with a source citation, and doubts the authenticity, because none found with attribution to Faraday prior to 1950. The earliest example Webmaster found is in 1929, by Walter Morley Fletcher in his Norman Lockyer Lecture. He refers to it as a “truism,” without mention of Faraday. He says “law of our state of being” rather than “natural law.” See the Walter Morley Fletcher page for more details.
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A neat and orderly laboratory is unlikely. It is, after all, so much a place of false starts and multiple attempts.
[Unverified. Please contact Webmaster if you can identify the primary source.]
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A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 140-141.
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A research laboratory jealous of its reputation has to develop less formal, more intimate ways of forming a corporate judgment of the work its people do. The best laboratories in university departments are well known for their searching, mutual questioning.
In Editorial, 'Is Science Really a Pack of Lies', Nature (1983), 303, 1257. As quoted and cited in Bradley P. Fuhrman, Jerry J. Zimmerman, Pediatric Critical Care (2011).
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A study of Disease—of Pestilences methodically prepared and deliberately launched upon man and beast—is certainly being pursued in the laboratories of more than one great country. Blight to destroy crops, Anthrax to slay horses and cattle, Plague to poison not armies but whole districts—such are the lines along which military science is remorselessly advancing.
'Shall We All Commit Suicide?'. Pall Mall (Sep 1924). Reprinted in Thoughts and Adventures (1932), 250.
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A tidy laboratory means a lazy chemist.
Berzelius to Nils Sefstrom, 8th July 1812. In C. G. Bernard, 'Berzelius as a European Traveller', in E. M. Melhardo and T. Frängsmyr (eds.), Enlightenment Science in the Romantic Era (1992), 225.
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According to my views, aiming at quantitative investigations, that is at establishing relations between measurements of phenomena, should take first place in the experimental practice of physics. By measurement to knowledge [door meten tot weten] I should like to write as a motto above the entrance to every physics laboratory.
'The Significance of Quantitative Research in Physics', Inaugural Address at the University of Leiden (1882). In Hendrik Casimir, Haphazard Reality: Half a Century of Science (1983), 160-1.
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Alexander Langmuir was quoted in the early 1960s instructing incoming Epidemic Intelligence Service (EIS) officers that the only need for the laboratory in an outbreak investigation was to “prove their conclusions were right.” (2011)
As given in epigraph to Chap. 9, in Centers for Disease Control and Prevention, The CDC Field Epidemiology Manual (2018), 188. A footnoted reference explains: “Langmuir’s point was not to denigrate the laboratory but to emphasize the power of an investigation based on a solid clinical case definition and established field epidemiologic principles,” in Walter R. Dowdle (corresponding author), Leonard W. Mayer, Karen K. Steinberg, Neelam D. Ghiya and Tanja Popovic (co-authors), 'CDC Laboratory Contributions to Public Health', Morbidity and Mortality Weekly Report, Supplements (7 Oct 2011), 60, 27.
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All the world is a laboratory to the inquiring mind.
Martin H. Fischer, Howard Fabing (ed.) and Ray Marr (ed.), Fischerisms (1944).
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All things on the earth are the result of chemical combination. The operation by which the commingling of molecules and the interchange of atoms take place we can imitate in our laboratories; but in nature they proceed by slow degrees, and, in general, in our hands they are distinguished by suddenness of action. In nature chemical power is distributed over a long period of time, and the process of change is scarcely to be observed. By acts we concentrate chemical force, and expend it in producing a change which occupies but a few hours at most.
In chapter 'Chemical Forces', The Poetry of Science: Or, Studies of the Physical Phenomena of Nature (1848), 235-236. Charles Dicken used this quote, with his own sub-head of 'Relative Importance Of Time To Man And Nature', to conclude his review of the book, published in The Examiner (1848).
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An intelligent patient, private or otherwise, to whom you have taken the trouble to explain the nature of the investigation, makes the best laboratory animal.
'Some of the ‘Do’s’ and ‘Do-Nots’ in Clinical Investigation,' Journal of Clinical Investigation (1944), 23, 921-26.
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As he approached the place where a meeting of doctors was being held, he saw some elegant limousines and remarked, “The surgeons have arrived.” Then he saw some cheaper cars and said, “The physicians are here, too.” ... And when he saw a row of overshoes inside, under the hat rack, he is reported to have remarked, “Ah, I see there are laboratory men here.”
The Way of an Investigator (1945, 1965), 207.
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As long as museums and universities send out expeditions to bring to light new forms of living and extinct animals and new data illustrating the interrelations of organisms and their environments, as long as anatomists desire a broad comparative basis human for anatomy, as long as even a few students feel a strong curiosity to learn about the course of evolution and relationships of animals, the old problems of taxonomy, phylogeny and evolution will gradually reassert themselves even in competition with brilliant and highly fruitful laboratory studies in cytology, genetics and physiological chemistry.
'Genetics Versus Paleontology', The American Naturalist, 1917, 51, 623.
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Ask a scientist what he conceives the scientific method to be, and he will adopt an expression that is at once solemn and shifty eyed: solemn because he feels he ought to declare an opinion; shifty eyed because he is wondering how to conceal the fact that he has no opinion to declare. If taunted he would probably mumble something about “Induction” and “Establishing the Laws of Nature”, but if anyone working in a laboratory professed to be trying to establish the Laws of Nature by induction, we should think he was overdue for leave.
From a Jayne Lecture (1968), 'Induction and Intuition in Scientific Thought', printed in Memoirs of the American Philosophical Society (1969), Vol. 75. Lecture republished as Induction and Intuition in Scientific Thought (2009), 11. Also included in Peter Medawar, Pluto’s Republic (1984), 80.
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At my urgent request the Curie laboratory, in which radium was discovered a short time ago, was shown to me. The Curies themselves were away travelling. It was a cross between a stable and a potato-cellar, and, if I had not seen the worktable with the chemical apparatus, I would have thought it a practical joke.
Wilhelm Ostwald on seeing the Curie's laboratory facilities.
In R. Reid, Marie Curie (1974), 95.
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At the Lawrence Radiation Laboratory, we have long had a tradition of close cooperation between physicists and technicians.
From Nobel Lecture (11 Dec 1968). Collected in Yong Zhou (ed.), Nobel Lecture: Physics, 1963-1970 (2013), 250.
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Away from their laboratories, physicist and chemist are but disarmed soldiers on a battlefield.
Hors de leurs laboratoires, le physicien et le chimiste sont des soldats sans armes sur le champ de bataille.
In article 'The Budget of Science', Revue des Cours Scientifiques (1 Feb 1868) and published as a pamphlet, Some Reflections on Science in France. Original French quote in René Vallery-Radot, La Vie de Pasteur (1900), 215. As translated in René Vallery-Radot and Mrs R. L. Devonshire (trans.) The Life of Pasteur (1902), 199. Also translated as “Outside their laboratories, the physicist and chemist are soldiers without arms on the field of battle.”
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AZT stood up and said, 'Stop your pessimism. Stop your sense of futility. Go back to the lab. Go back to development. Go back to clinical trials. Things will work.'
[On the impact of AZT emerging as the long-sought first significant AIDS drug.]
As quoted in Emily Langer, 'Researcher Jerome P. Horwitz, 93, created AZT, the first approved treatment for HIV/AIDS' Washington Post (19 Sep 2012). The article was excerpted on blogs, sometimes referring to this quote by saying "AZT was more a cure for fatalism than for AIDS."
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Besides science museums, which hold stocks of artifacts, there are science centres which show manufactured models. Everyone knows that the best way to teach science is by doing experiments. Science centres are in effect public science laboratories … that enable the public to try scientific experiments with their own hands.
In 'Early Days in University Geophysics', Annual Review of Earth and Planetary Sciences (1982), 10, 13.
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But for twenty years previous to 1847 a force had been at work in a little county town of Germany destined to effect the education of Christendom, and at the same time to enlarge the boundaries of human knowledge, first in chemistry and the allied branches, then in every other one of the natural sciences. The place was Giessen; the inventor Liebig; the method, a laboratory for instruction and research.
A Semi-Centennial Discourse, 1847-97' (28 Oct 1897), The Sheffield Scientific School of Yale University. Quoted in Daniel Coit Gilman, University Problems in the United States (1898), 120.
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But when we face the great questions about gravitation Does it require time? Is it polar to the 'outside of the universe' or to anything? Has it any reference to electricity? or does it stand on the very foundation of matter–mass or inertia? then we feel the need of tests, whether they be comets or nebulae or laboratory experiments or bold questions as to the truth of received opinions.
Letter to Michael Faraday, 9 Nov 1857. In P. M. Harman (ed.), The Scientific Letters and Papers of James Clerk Maxwell (1990), Vol. 1, 1846-1862, 551-2.
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But, contrary to the lady’s prejudices about the engineering profession, the fact is that quite some time ago the tables were turned between theory and applications in the physical sciences. Since World War II the discoveries that have changed the world are not made so much in lofty halls of theoretical physics as in the less-noticed labs of engineering and experimental physics. The roles of pure and applied science have been reversed; they are no longer what they were in the golden age of physics, in the age of Einstein, Schrödinger, Fermi and Dirac.
'The Age of Computing: a Personal Memoir', Daedalus (1992), 121, 120.
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By research in pure science I mean research made without any idea of application to industrial matters but solely with the view of extending our knowledge of the Laws of Nature. I will give just one example of the ‘utility’ of this kind of research, one that has been brought into great prominence by the War—I mean the use of X-rays in surgery. Now, not to speak of what is beyond money value, the saving of pain, or, it may be, the life of the wounded, and of bitter grief to those who loved them, the benefit which the state has derived from the restoration of so many to life and limb, able to render services which would otherwise have been lost, is almost incalculable. Now, how was this method discovered? It was not the result of a research in applied science starting to find an improved method of locating bullet wounds. This might have led to improved probes, but we cannot imagine it leading to the discovery of X-rays. No, this method is due to an investigation in pure science, made with the object of discovering what is the nature of Electricity. The experiments which led to this discovery seemed to be as remote from ‘humanistic interest’ —to use a much misappropriated word—as anything that could well be imagined. The apparatus consisted of glass vessels from which the last drops of air had been sucked, and which emitted a weird greenish light when stimulated by formidable looking instruments called induction coils. Near by, perhaps, were great coils of wire and iron built up into electro-magnets. I know well the impression it made on the average spectator, for I have been occupied in experiments of this kind nearly all my life, notwithstanding the advice, given in perfect good faith, by non-scientific visitors to the laboratory, to put that aside and spend my time on something useful.
In Speech made on behalf of a delegation from the Conjoint Board of Scientific Studies in 1916 to Lord Crewe, then Lord President of the Council. In George Paget Thomson, J. J. Thomson and the Cavendish Laboratory in His Day (1965), 167-8.
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Considered from the standpoint of chemistry, living bodies appear to us as laboratories of chemical processes, for they undergo perpetual changes in their material substrate. They draw materials from the outside world and combine them with the mass of their liquid and solid parts.
In 'Allgemeine Betrachtungen der orgauischen Korper', Physiologie des Menschen (1830), Vol. 1, 34. Trans. in Kenneth L. Caneva, Robert Mayer and the Conservation of Energy (1993), 7I.
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Creativity in science, as in the arts, cannot be organized. It arises spontaneously from individual talent. Well-run laboratories can foster it, but hierarchical organization, inflexible, bureaucratic rules, and mounds of futile paperwork can kill it. Discoveries cannot be planned; they pop up, like Puck, in unexpected corners.
In 'Preface', I Wish I’d Made You Angry Earlier: Essays on Science, Scientists, and Humanity (1998), ix.
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D’you know how embarrassing it is to mention good and evil in a scientific laboratory? Have you any idea? One of the reasons l became a scientist was not to have to think about that kind of thing.
Spoken by character Dr. Malone in His Dark Materials Omnibus (2012), 370.
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Dewar’s rule in his laboratory was as absolute as that of a Pharaoh, and he showed deference to no one except the ghost of Faraday whom he met occasionally all night in the gallery behind the lecture room.
In The Quest for Absolute Zero (1945, 1966), 73.
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Dick Drew took a bunch of misfits—people who wouldn’t fly in formation—and he put together a lab that created technologies that account for 20 percent of 3M's sales in 2000.
Art Fry
As quoted in W. James McNerney Jr., A Century of Innovation: The 3M Story (2002), 26.
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Direct observation of the testimony of the earth … is a matter of the laboratory, of the field naturalist, of indefatigable digging among the ancient archives of the earth’s history. If Mr. Bryan, with an open heart and mind, would drop all his books and all the disputations among the doctors and study first hand the simple archives of Nature, all his doubts would disappear; he would not lose his religion; he would become an evolutionist.
'Evolution and Religion', New York Times (5 Mar 1922), 91. Written in response to an article a few days earlier in which William Jennings Bryan challenged the theory of evolution as lacking proof.
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Don’t despise empiric truth. Lots of things work in practice for which the laboratory has never found proof.
Martin H. Fischer, Howard Fabing (ed.) and Ray Marr (ed.), Fischerisms (1944).
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During an intense period of lab work, the outside world vanishes and the obsession is total. Sleep is when you can curl up on the accelerator floor for an hour.
In Leon Lederman and Dick Teresi, The God Particle: If the Universe is the Answer, What is the Question (1993), 14-15.
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During his Zurich stay the woman doctor, Paulette Brubacher, asked the whereabouts of his [Einstein's] laboratory. With a smile he took a fountain pen out of his breast pocket and said: 'here'.
C. Seelig, Albert Einstein: A Documentary Biography (1956), 154.
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Dust consisting of fine fibers of asbestos, which are insoluble and virtually indestructible, may become a public health problem in the near future. At a recent international conference on the biological effects of asbestos sponsored by the New York Academy of Sciences, participants pointed out on the one hand that workers exposed to asbestos dust are prone in later life to develop lung cancer, and on the other hand that the use of this family of fibrous silicate compounds has expanded enormously during the past few decades. A laboratory curiosity 100 years ago, asbestos today is a major component of building materials.
In Scientific American (Sep 1964). As cited in '50, 100 & 150 Years Ago', Scientific American (Dec 2014), 311, No. 6, 98.
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Each human life is unique, born of a miracle that reaches beyond laboratory science.
Quoted in Kim Lim (ed.), 1,001 Pearls of Spiritual Wisdom: Words to Enrich, Inspire, and Guide Your Life (2014), 42
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England and all civilised nations stand in deadly peril of not having enough to eat. As mouths multiply, food resources dwindle. Land is a limited quantity, and the land that will grow wheat is absolutely dependent on difficult and capricious natural phenomena... I hope to point a way out of the colossal dilemma. It is the chemist who must come to the rescue of the threatened communities. It is through the laboratory that starvation may ultimately be turned into plenty... The fixation of atmospheric nitrogen is one of the great discoveries, awaiting the genius of chemists.
Presidential Address to the British Association for the Advancement of Science 1898. Published in Chemical News, 1898, 78, 125.
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Everybody’s a mad scientist, and life is their lab. We’re all trying to experiment to find a way to live, to solve problems, to fend off madness and chaos.
In David Chronenberg and Chris Rodley (ed.), Chronenberg on Chronenberg (1992), 7. As cited in Carl Royer, B Lee Cooper, The Spectacle of Isolation in Horror Films: Dark Parades (2013), 55.
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Experiments in geology are far more difficult than in physics and chemistry because of the greater size of the objects, commonly outside our laboratories, up to the earth itself, and also because of the fact that the geologic time scale exceeds the human time scale by a million and more times. This difference in time allows only direct observations of the actual geologic processes, the mind having to imagine what could possibly have happened in the past.
In 'The Scientific Character of Geology', The Journal of Geology (Jul 1961), 69, No. 4, 455-6.
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First they said my [cyclol] structure [of proteins] couldn’t exist. Then when it was found in Nature they said it couldn’t be synthesized in a laboratory. Then when it was synthesized they said it wasn’t important in any way.
Quoted in Maureen M. Julian in G. Kass­Simon and Patricia Farnes (eds.), Women of Science (1990), 368.
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For the better part of my last semester at Garden City High, I constructed a physical pendulum and used it to make a “precision” measurement of gravity. The years of experience building things taught me skills that were directly applicable to the construction of the pendulum. Twenty-five years later, I was to develop a refined version of this measurement using laser-cooled atoms in an atomic fountain interferometer.
[Outcome of high school physics teacher, Thomas Miner, encouraging Chu's ambitious laboratory project.]
Autobiography in Gösta Ekspong (ed.), Nobel Lectures: Physics 1996-2000 (2002), 116.
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For they are not given to idleness, nor go in a proud habit, or plush and velvet garments, often showing their rings upon their fingers, or wearing swords with silver hilts by their sides, or fine and gay gloves upon their hands, but diligently follow their labours, sweating whole days and nights by their furnaces. They do not spend their time abroad for recreation, but take delight in their laboratory. They wear leather garments with a pouch, and an apron wherewith they wipe their hands. They put their fingers amongst coals, into clay, and filth, not into gold rings. They are sooty and black like smiths and colliers, and do not pride themselves upon clean and beautiful faces.
As translated in Paracelsus and Arthur Edward Waite (ed.), The Hermetic and Alchemical Writings of Paracelsus (1894, 1976), Vol. 1, 167.
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From all we have learnt about the structure of living matter, we must be prepared to find it working in a manner that cannot be reduced to the ordinary laws of physics. And that not on the ground that there is any “new force” or what not, directing the behavior of the single atoms within a living organism, but because the construction is different from anything we have yet tested in the physical laboratory.
What is Life? (1956), 74.
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From him [Wilard Bennett] I learned how different a working laboratory is from a student laboratory. The answers are not known!
[While an undergraduate, doing experimental measurements in the laboratory of his professor, at Ohio State University.]
From autobiography on Nobel Prize website.
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Genetics has enticed a great many explorers during the past two decades. They have labored with fruit-flies and guinea-pigs, with sweet peas and corn, with thousands of animals and plants in fact, and they have made heredity no longer a mystery but an exact science to be ranked close behind physics and chemistry in definiteness of conception. One is inclined to believe, however, that the unique magnetic attraction of genetics lies in the vision of potential good which it holds for mankind rather than a circumscribed interest in the hereditary mechanisms of the lowly species used as laboratory material. If man had been found to be sharply demarcated from the rest of the occupants of the world, so that his heritage of physical form, of physiological function, and of mental attributes came about in a superior manner setting him apart as lord of creation, interest in the genetics of the humbler organisms—if one admits the truth—would have flagged severely. Biologists would have turned their attention largely to the ways of human heredity, in spite of the fact that the difficulties encountered would have rendered progress slow and uncertain. Since this was not the case, since the laws ruling the inheritance of the denizens of the garden and the inmates of the stable were found to be applicable to prince and potentate as well, one could shut himself up in his laboratory and labor to his heart's content, feeling certain that any truth which it fell to his lot to discover had a real human interest, after all.
Mankind at the Crossroads (1923), v-vi.
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Geology has its peculiar difficulties, from which all other sciences are exempt. Questions in chemistry may be settled in the laboratory by experiment. Mathematical and philosophical questions may be discussed, while the materials for discussion are ready furnished by our own intellectual reflections. Plants, animals and minerals, may be arranged in the museum, and all questions relating to their intrinsic principles may be discussed with facility. But the relative positions, the shades of difference, the peculiar complexions, whether continuous or in subordinate beds, are subjects of enquiry in settling the character of rocks, which can be judged of while they are in situ only.
A Geological and Agricultural Survey of the District Adjoining the Erie Canal (1824), 8.
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God has ordered all his Creation by Weight and Measure.
Written over the door of the world's first instructional laboratory, founded at Giessen, 1824.
As given in Patterns of Survival: An Anatomy of Life (1938), 2. It is based on a line from the Bible in Wisdom of Solomon, Chap. 11, Verse 20. Webmaster presumes this is the English translation, but Liebig used the dictum written in German. Contact webmaster if you know the specific wording of the original.
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Graduates engaged in post-graduate work are reminded that their Supervisor is a University Officer and when visiting him officially in that capacity they should dress as they would in visiting any other officers of the University or of their own College (e.g. a tutor). Gowns, however, need not be worn in the chemical laboratory.
Note from Lennard-Jones to his PhD student, Charles Coulson, 14 Jul 1933. Quoted in S. C. Altham and E. J. Bowen, 'Charles Alfred Coulson 1910-1974', Biographical Memoirs of Fellows of the Royal Society (1974), 20, 78.
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Guard against both doing experiments simply because they are likely to yield easy or easily manipulated results or because they are what a lively laboratory imagination is able to invent.
From archive recording (3 Jun 1959) with to John C. Kenna, giving his recollection of his farewell speech to Cambridge Psychological Society (4 Mar 1952), in which he gave a summary of points he considered to be basic requirements for a good experimental psychologist. Part of point 4 of 7, from transcription of recording held at British Psychological Society History of Psychology Centre, London, as abridged on thepsychologist.bps.org.uk website.
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He [Robert Boyle] is very tall (about six foot high) and straight, very temperate, and vertuouse, and frugall: a batcheler; keepes a Coach; sojournes with his sister, the Lady Ranulagh. His greatest delight is Chymistrey. He has at his sister’s a noble laboratory, and severall servants (Prentices to him) to look to it. He is charitable to ingeniose men that are in want, and foreigne Chymists have had large proofe of his bountie, for he will not spare for cost to get any rare Secret.
John Aubrey, Brief Lives (1680), edited by Oliver Lawson Dick (1949), 37.
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His [Edison’s] greatest invention was that of the industrial research laboratory, turning out inventions as a business.
In The Human Use of Human Beings: Cybernetics and Society (1950), 127.
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How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.
Interview with American Analyst. Reprinted in Pacific Record of Medicine and Surgery (1886), 1, No. 3, 78.
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Hypotheses like professors, when they are seen not to work any longer in the laboratory, should disappear.
Sir Harold Hartley, 'Henry Armstrong', in Studies in the History of Chemistry (1971), 199.
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I always tried to live up to Leo Szilard's commandment, “don't lie if you don't have to.” I had to. I filled up pages with words and plans I knew I would not follow. When I go home from my laboratory in the late afternoon, I often do not know what I am going to do the next day. I expect to think that up during the night. How could I tell them what I would do a year hence?
In 'Dionysians and Apollonians', Science (2 Jun 1972), 176, 966. Reprinted in Mary Ritchie Key, The Relationship of Verbal and Nonverbal Communication (1980), 318.
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I am among those who think that science has great beauty. A scientist in his laboratory is not only a technician: he is also a child placed before natural phenomena which impress him like a fairy tale. We should not allow it to be believed that all scientific progress can be reduced to mechanisms, machines, gearings, even though such machinery has its own beauty.
During a debate in Madrid, ',The Future of Culture' (1933). In Eve Curie Labouisse, Eve Curie and Vincent Sheean, Madame Curie (1937), 341
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I am sorry that the distinguished leader of the Republican Party in the House states that he is not versed in botany and publicly admits that he does not know anything of these terms or what it is all about; but, Mr. Chairman, it is indeed a sad day for the people of this country when we must close the doors of the laboratories doing research work for the people of the United States.
Speaking (28 Dec 1932) as a member of the 72nd Congress, early in the Great Depression, in opposition to an attempt to eliminate a small amount from the agricultural appropriation bill. As quoted in 'Mayor-Elect La Guardia on Research', Science (1933), New Series, 78, No. 2031, 511.
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I came from Paris in the Spring of 1884, and was brought in intimate contact with him [Thomas Edison]. We experimented day and night, holidays not excepted. His existence was made up of alternate periods of work and sleep in the laboratory. He had no hobby, cared for no sport or amusement of any kind and lived in utter disregard of the most elementary rules of hygiene. There can be no doubt that, if he had not married later a woman of exceptional intelligence, who made it the one object of her life to preserve him, he would have died many years ago from consequences of sheer neglect. So great and uncontrollable was his passion for work.
As quoted in 'Tesla Says Edison Was an Empiricist', The New York Times (19 Oct 1931), 25.
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I can conceive few human states more enviable than that of the man to whom, panting in the foul laboratory, or watching for his life under the tropic forest, Isis shall for a moment lift her sacred veil, and show him, once and for ever, the thing he dreamed not of; some law, or even mere hint of a law, explaining one fact; but explaining with it a thousand more, connecting them all with each other and with the mighty whole, till order and meaning shoots through some old Chaos of scattered observations.
Health and Education (1874), 289.
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I can see him [Sylvester] now, with his white beard and few locks of gray hair, his forehead wrinkled o’er with thoughts, writing rapidly his figures and formulae on the board, sometimes explaining as he wrote, while we, his listeners, caught the reflected sounds from the board. But stop, something is not right, he pauses, his hand goes to his forehead to help his thought, he goes over the work again, emphasizes the leading points, and finally discovers his difficulty. Perhaps it is some error in his figures, perhaps an oversight in the reasoning. Sometimes, however, the difficulty is not elucidated, and then there is not much to the rest of the lecture. But at the next lecture we would hear of some new discovery that was the outcome of that difficulty, and of some article for the Journal, which he had begun. If a text-book had been taken up at the beginning, with the intention of following it, that text-book was most likely doomed to oblivion for the rest of the term, or until the class had been made listeners to every new thought and principle that had sprung from the laboratory of his mind, in consequence of that first difficulty. Other difficulties would soon appear, so that no text-book could last more than half of the term. In this way his class listened to almost all of the work that subsequently appeared in the Journal. It seemed to be the quality of his mind that he must adhere to one subject. He would think about it, talk about it to his class, and finally write about it for the Journal. The merest accident might start him, but once started, every moment, every thought was given to it, and, as much as possible, he read what others had done in the same direction; but this last seemed to be his real point; he could not read without finding difficulties in the way of understanding the author. Thus, often his own work reproduced what had been done by others, and he did not find it out until too late.
A notable example of this is in his theory of cyclotomic functions, which he had reproduced in several foreign journals, only to find that he had been greatly anticipated by foreign authors. It was manifest, one of the critics said, that the learned professor had not read Rummer’s elementary results in the theory of ideal primes. Yet Professor Smith’s report on the theory of numbers, which contained a full synopsis of Kummer’s theory, was Professor Sylvester’s constant companion.
This weakness of Professor Sylvester, in not being able to read what others had done, is perhaps a concomitant of his peculiar genius. Other minds could pass over little difficulties and not be troubled by them, and so go on to a final understanding of the results of the author. But not so with him. A difficulty, however small, worried him, and he was sure to have difficulties until the subject had been worked over in his own way, to correspond with his own mode of thought. To read the work of others, meant therefore to him an almost independent development of it. Like the man whose pleasure in life is to pioneer the way for society into the forests, his rugged mind could derive satisfaction only in hewing out its own paths; and only when his efforts brought him into the uncleared fields of mathematics did he find his place in the Universe.
In Florian Cajori, Teaching and History of Mathematics in the United States (1890), 266-267.
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I feel that to be a director of a laboratory should not be, by definition, a permanent mission. People should have the courage to step down and go back to science. I believe you will never have a good director of a scientific laboratory unless that director knows he is prepared to become a scientist again. … I gave my contribution; I spent five years of my life to work hard for other people’s interest. … It’s time to go back to science again. I have some wonderful ideas, I feel I’m re-born.
From 'Asking Nature', collected in Lewis Wolpert and Alison Richards (eds.), Passionate Minds: The Inner World of Scientists (1997), 202.
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I feel that, in a sense, the writer knows nothing any longer. He has no moral stance. He offers the reader the contents of his own head, a set of options and imaginative alternatives. His role is that of a scientist, whether on safari or in his laboratory, faced with an unknown terrain or subject. All he can do is to devise various hypotheses and test them against the facts.
Crash (1973, 1995), Introduction. In Barry Atkins, More Than A Game: the Computer Game as a Fictional Form (2003), 144.
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I had intended to major in physics … I could never seem to get the labs to come out right. So I switched to math and have been interested in it ever since.
In 'A Personal Profile of Karen K. Uhlenbeck', collected in Susan Ambrose et al., Journeys of Women in Science and Engineering, No Universal Constants (1999). Uhlenbeck’s father was an engineer and her father-in-law was a famous physicist.
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I hadn’t been aware that there were doors closed to me until I started knocking on them. I went to an all-girls school. There were 75 chemistry majors in that class, but most were going to teach it … When I got out and they didn't want women in the laboratory, it was a shock … It was the Depression and nobody was getting jobs. But I had taken that to mean nobody was getting jobs … [when I heard] “You're qualified. But we’ve never had a woman in the laboratory before, and we think you’d be a distracting influence.”
As quoted in Sharon Bertsch McGrayne, Nobel Prize Women in Science: Their Lives, Struggles and Momentous Discoveries (1993).
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I happened to read recently a remark by American nuclear physicist W. Davidson, who noted that the explosion of one hydrogen bomb releases a greater amount of energy than the explosions set off by all countries in all wars known in the entire history of mankind. And he, apparently, is right.
[The quoted physicist was, in fact, William Davidon, Argonne National Laboratory.]
Address to the United Nations, New York City, 18 Sep 1959. Quoted in 'Texts of Khrushchev's Address at United Nations and the Soviet Declaration', New York Times (19 Sep 1959), 8.
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I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this—never neglect an extraordinary appearance or happening. It may be—usually is, in fact—a false alarm that leads to nothing, but may on the other hand be the clue provided by fate to lead you to some important advance.
Lecture at Harvard University. Quoted in Joseph Sambrook, David W. Russell, Molecular Cloning (2001), Vol. 1, 153.
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I have never had any student or pupil under me to aid me with assistance; but have always prepared and made my experiments with my own hands, working & thinking at the same time. I do not think I could work in company, or think aloud, or explain my thoughts at the time. Sometimes I and my assistant have been in the Laboratory for hours & days together, he preparing some lecture apparatus or cleaning up, & scarcely a word has passed between us; — all this being a consequence of the solitary & isolated system of investigation; in contradistinction to that pursued by a Professor with his aids & pupils as in your Universities.
Letter to C. Ransteed, 16 Dec 1857. In L. Pearce Williams (ed.), The Selected Correspondence of Michael Faraday (1971), Vol. 2, 888.
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I have no dress except the one I wear every day. If you are going to be kind enough to give me one, please let it be practical and dark so that I can put it on afterwards to go to the laboratory.
[Referring to her wedding dress.]
In Eve Curie, Madame Curie: a biography by Eve Curie (1937, 2007), 136-37.
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I have seen many phases of life; I have moved in imperial circles, I have been a Minister of State; but if I had to live my life again, I would always remain in my laboratory, for the greatest joy of my life has been to accomplish original scientific work, and, next to that, to lecture to a set of intelligent students.
Quoted in Ralph Oesper, The Human Side of Scientists (1975), 55.
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I have taken up my lodgings in the loft of the laboratory building itself and am so quite at home with chemical apparatus and preparations all around, “they are congenial spirits,” as Mr. Silliman remarked when he showed me the room.
Letter to a friend (25 Jun 1845) as quoted by Frank Dawson Adams, in 'Biographical Memoir of Thomas Sterry Hunt' presented to the Annual Meeting of the National Academy of Sciences (1932). Hunt was Professor Silliman Jr’s student and assistant at the Scientific School of Yale University.
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I learned easily mathematics and physics, as far as these sciences were taken in consideration in the school. I found in this ready help from my father, who loved science and had to teach it himself. He enjoyed any explanation he could give us about Nature and her ways. Unhappily, he had no laboratory and could not perform experiments.
About her childhood schooling. As translated by Charlotte and Vernon Kellogg in Marie Curie, 'Autobiographical Notes', Pierre Curie (1923), 188. [Her father, Władysław Skłodowski, had studied Physics and Mathematics at the St. Petersburg University. For the early years of his career, he was a teacher in Warsaw schools. —Webmaster]]
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I noticed affixed to a laboratory door the following words: “Les théories passent. Le Grenouille reste. [The theories pass. The frog remains.] &mdashJean Rostand, Carnets d’un biologiste.” There is a risk that in the less severe discipline of criticism the result may turn out to be different; the theories will remain but the frog may disappear.
In An Appetite for Poetry (1989), 5.
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I ought to say that one of our first joint researches, so far as publication was concerned, had the peculiar effect of freeing me forever from the wiles of college football, and if that is a defect, make the most of it! Dr. Noyes and I conceived an idea on sodium aluminate solutions on the morning of the day of a Princeton-Harvard game (as I recall it) that we had planned to attend. It looked as though a few days' work on freezing-point determinations and electrical conductivities would answer the question. We could not wait, so we gave up the game and stayed in the laboratory. Our experiments were successful. I think that this was the last game I have ever cared about seeing. I mention this as a warning, because this immunity might attack anyone. I find that I still complainingly wonder at the present position of football in American education.
Address upon receiving the Perkin Medal Award, 'The Big Things in Chemistry', The Journal of Industrial and Engineering Chemistry (Feb 1921), 13, No. 2, 162-163.
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I prefer the spagyric chemical physicians, for they do not consort with loafers or go about gorgeous in satins, silks and velvets, gold rings on their fingers, silver daggers hanging at their sides and white gloves on their hands, but they tend their work at the fire patiently day and night. They do not go promenading, but seek their recreation in the laboratory, wear plain learthern dress and aprons of hide upon which to wipe their hands, thrust their fingers amongst the coals, into dirt and rubbish and not into golden rings. They are sooty and dirty like the smiths and charcoal burners, and hence make little show, make not many words and gossip with their patients, do not highly praise their own remedies, for they well know that the work must praise the master, not the master praise his work. They well know that words and chatter do not help the sick nor cure them... Therefore they let such things alone and busy themselves with working with their fires and learning the steps of alchemy. These are distillation, solution, putrefaction, extraction, calcination, reverberation, sublimination, fixation, separation, reduction, coagulation, tinction, etc.
Quoted in R. Oesper, The Human Side of Scientists (1975), 150. [Spagyric is a form of herbalism based on alchemic procedures of preparation.]
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I said to myself, if there's a group of these people that are so courageous and so selfless, somebody ought to carry their damn banner and do something about. That's 1965. I was 20 years old. I said I was going to commit my career to curing paralysis.
Referring to the paralyzed veteran volunteers in the spinal cord injury laboratory with whom Green worked while attending medical school.
Quoted in Jennifer Kay 'Neurosurgeon Barth Green: Football player's treatment available to all', Associated Press news report, USA Today website (posted 27 Sep 2007).
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I shall attack Chemistry, like a Shark.
On his plans to set up a joint chemistry laboratory with Davy and Wordsworth in the Lake District.
Letter to Humphry Davy, 15 July 1800. In Earl Leslie Griggs (ed.), The Collected Letters of Samuel Taylor Coleridge (1956), Vol. 1, 605.
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Josiah Dwight Whitney quote: Liebig is a remarkable man, who has done much for organic Chemistry
I suppose I should be run after for a professorship if I had studied at Giessen, as it seems to be a settled point that no young man can be expected to know anything of chemistry unless he has studied with Liebig; while the truth is, that any one who goes there and does not afterwards correct the bad habits acquired there, in some other laboratory, is almost unfitted for doing things in Chemistry. No doubt Liebig is a remarkable man, who has done much for organic Chemistry, not to speak of his having quarreled with all the Chemists in Europe...
Letter to his brother, William Dwight Whitney (25 Apr 1846). In Edwin Tenney Brewster and Josiah Dwight Whitney, Life and Letters of Josiah Dwight Whitney (1909), 79-80.
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I want to get out in the water. I want to see fish, real fish, not fish in a laboratory.
Interview (27 Jan 1991), on Academy of Achievement website.
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I was fascinated by fractional distillation as a method while still a school-boy, and built in the cellar of my home, which was my combined workshop and laboratory, distillation columns, packed with coke of graded size, some five feet in height. They were made from coffee tins (obtained from the kitchen), with the bottoms removed and soldered together! Experience with them served me in good stead and by the time I graduated I had a good understanding of the problems of fractional distillation.
Nobel Lectures in Chemistry (1999), Vol. 3, 359-360.
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I was one of those nerds before the name was popular. I spent all my time in the electrical engineering laboratory and not enough time socializing.
In transcript of a video history interview with Seymour Cray by David K. Allison at the National Museum of American History, Smithsonian Institution, (9 May 1995), 4.
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I was working with these very long-chain … extended-chain polymers, where you had a lot of benzene rings in them. … Transforming a polymer solution from a liquid to a fiber requires a process called spinning. … We spun it and it spun beautifully. It [Kevlar] was very strong and very stiff—unlike anything we had made before. I knew that I had made a discovery. I didn’t shout “Eureka!” but I was very excited, as was the whole laboratory excited, and management was excited, because we were looking for something new. Something different. And this was it.
From transcript for video interview (2007, published Aug 2012), 'Stephanie Kwolek: Curiosity and the Discovery of Kevlar', in the series Women in Chemistry, on Chemical Heritage Foundation website.
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I went to the trash pile at Tuskegee Institute and started my laboratory with bottles, old fruit jars and any other thing I found I could use. … [The early efforts were] worked out almost wholly on top of my flat topped writing desk and with teacups, glasses, bottles and reagents I made myself.
Manuscript fragment, no date, Box 1, George Washington Carver Papers. Cited in Linda O. McMurry, George Washington Carver, Scientist and Symbol (1982), 130.
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I would like to emphasize strongly my belief that the era of computing chemists, when hundreds if not thousands of chemists will go to the computing machine instead of the laboratory for increasingly many facets of chemical information, is already at hand. There is only one obstacle, namely that someone must pay for the computing time.
'Spectroscopy, Molecular Orbitals, and Chemical Bonding', Nobel Lecture (12 Dec 1966). In Nobel Lectures: Chemistry 1963-1970 (1972), 159.
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I would picture myself as a virus, or as a cancer cell, for example, and try to sense what it would be like to be either. I would also imagine myself as the immune system, and I would try to reconstruct what I would do as an immune system engaged in combating a virus or cancer cell. When I had played through a series of such scenarios on a particular problem and had acquired new insights, I would design laboratory experiments accordingly… Based upon the results of the experiment, I would then know what question to ask next… When I observed phenomena in the laboratory that I did not understand, I would also ask questions as if interrogating myself: “Why would I do that if I were a virus or a cancer cell, or the immune system?” Before long, this internal dialogue became second nature to me; I found that my mind worked this way all the time.
In Anatomy of Reality: Merging of Intuition and Reason (1983), 7, footnote b, as quoted and cited in Roger Frantz, Two Minds: Intuition and Analysis in the History of Economic Thought (2006), 7.
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If a little less time was devoted to the translation of letters by Julius Caesar describing Britain 2000 years ago and a little more time was spent on teaching children how to describe (in simple modern English) the method whereby ethylene was converted into polythene in 1933 in the ICI laboratories at Northwich, and to discussing the enormous social changes which have resulted from this discovery, then I believe that we should be training future leaders in this country to face the world of tomorrow far more effectively than we are at the present time.
Quoted in an Obituary, D. P. Craig, Biographical Memoirs of Fellows of the Royal Society (1972), 18, 461.
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If three simple questions and one well chosen laboratory test lead to an unambiguous diagnosis, why harry the patient with more?
Anonymous
Editorial, 'Clinical decision by numbers'. Lancet (1975) 1, 1077.
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If we peep into Dom Claude’s cell, we are introduced to a typical alchemist’s laboratory—a gloomy, dimly-lighted place, full of strange vessels, and furnaces, and melting-pots, spheres, and portions of skeletons hanging from the ceiling; the floor littered with stone bottles, pans, charcoal, aludels, and alembics, great parchment books covered with hieroglyphics; the bellows with its motto Spira, Spera; the hour-glass, the astrolabe, and over all cobwebs, and dust, and ashes. The walls covered with various aphorisms of the brotherhood; legends and memorials in many tongues; passages from the Smaragdine Table of Hermes Trismegistus; and looming out from all in great capitals, ’ANAΓKH.
In The Birth of Chemistry (1874), 100.
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If we want an answer from nature, we must put our questions in acts, not words, and the acts may take us to curious places. Some questions were answered in the laboratory, others in mines, others in a hospital where a surgeon pushed tubes in my arteries to get blood samples, others on top of Pike’s Peak in the Rocky Mountains, or in a diving dress on the bottom of the sea. That is one of the things I like about scientific research. You never know where it will take you next.
From essay 'Some Adventures of a Biologist', as quoted in Ruth Moore, Man, Time, And Fossils (1953), 174.
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If you were an artist or novelist, or a poet or somebody like that, nobody would think it odd if you worked in your own home. In science there’s none of this at all. I’m almost the only independent scientist in Britain. Everybody else works in large institutions, universities, or industrial labs. Why should one expect scientists to work that way?
From Visionaries documentary, 'The Man Who Named the World' (1989). As quoted on jameslovelock.org website.
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In 1906 I indulged my temper by hurling invectives at Neo-Darwinians in the following terms. “I really do not wish to be abusive [to Neo-Darwinians]; but when I think of these poor little dullards, with their precarious hold of just that corner of evolution that a blackbeetle can understand—with their retinue of twopenny-halfpenny Torquemadas wallowing in the infamies of the vivisector’s laboratory, and solemnly offering us as epoch-making discoveries their demonstrations that dogs get weaker and die if you give them no food; that intense pain makes mice sweat; and that if you cut off a dog’s leg the three-legged dog will have a four-legged puppy, I ask myself what spell has fallen on intelligent and humane men that they allow themselves to be imposed on by this rabble of dolts, blackguards, imposters, quacks, liars, and, worst of all, credulous conscientious fools.”
In Back to Methuselah: A Metabiological Pentateuch (1921), lxi
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In 1945 J.A. Ratcliffe … suggested that I [join his group at Cavendish Laboratory, Cambridge] to start an investigation of the radio emission from the Sun, which had recently been discovered accidentally with radar equipment. … [B]oth Ratcliffe and Sir Lawrence Bragg, then Cavendish Professor, gave enormous support and encouragement to me. Bragg’s own work on X-ray crystallography involved techniques very similar to those we were developing for “aperture synthesis,” and he always showed a delighted interest in the way our work progressed.
From Autobiography in Wilhelm Odelberg (ed.), Les Prix Nobel en 1974/Nobel Lectures (1975)
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In a famous passage, René Descartes tells us that he considered himself to be placed in three simultaneous domiciles, patiently recognizing his loyalties to the social past, fervidly believing in a final solution of nature’s secrets and in the meantime consecrated to the pursuit of scientific doubt. Here we have the half way house of the scientific laboratory, of the scientific mind in the midst of its campaign.
In 'The Three Dimensions of Time', Part I, 'The Classic of Science', A Classic and a Founder (1937), collected in Rosenstock-Huessy Papers (1981), Vol. 1, 14.
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In a University we are especially bound to recognise not only the unity of science itself, but the communion of the workers in science. We are too apt to suppose that we are congregated here merely to be within reach of certain appliances of study, such as museums and laboratories, libraries and lecturers, so that each of us may study what he prefers. I suppose that when the bees crowd round the flowers it is for the sake of the honey that they do so, never thinking that it is the dust which they are carrying from flower to flower which is to render possible a more splendid array of flowers, and a busier crowd of bees, in the years to come. We cannot, therefore, do better than improve the shining hour in helping forward the cross-fertilization of the sciences.
'The Telephone', Nature, 15, 1878. In W. D. Niven (ed.), The Scientific Papers of James Clerk Maxwell (1890), Vol. 2, 743-4.
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In a word, I consider hospitals only as the entrance to scientific medicine; they are the first field of observation which a physician enters; but the true sanctuary of medical science is a laboratory; only there can he seek explanations of life in the normal and pathological states by means of experimental analysis.
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 146.
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In general the actions which we see ever taking place around us are complex, or due to the simultaneous action of many causes. When, as in astronomy, we endeavour to ascertain these causes by simply watching their effects, we observe; when, as in our laboratories, we interfere arbitrarily with the causes or circumstances of a phenomenon, we are said to experiment.
In William Thomson and Peter Guthrie Tait, Treatise on Natural Philosophy (1867), Vol. 1, 305.
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In my own field, x-ray crystallography, we used to work out the structure of minerals by various dodges which we never bothered to write down, we just used them. Then Linus Pauling came along to the laboratory, saw what we were doing and wrote out what we now call Pauling's Rules. We had all been using Pauling's Rules for about three or four years before Pauling told us what the rules were.
In The Extension of Man (1972), 116.
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In one of my lectures many years ago I used the phrase “following the trail of light”. The word “light” was not meant in its literal sense, but in the sense of following an intellectual concept or idea to where it might lead. My interest in living things is probably a fundamental motivation for the scientific work in the laboratory, and we created here in Berkeley one of the first and foremost interdisciplinary laboratories in the world.
In autobiography, Following the Trail of Light: A Scientific Odyssey (1992), 134.
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In physics, mathematics, and astronautics [elderly] means over thirty; in the other disciplines, senile decay is sometimes postponed to the forties. There are, of course, glorious exceptions; but as every researcher just out of college knows, scientists of over fifty are good for nothing but board meetings, and should at all costs be kept out of the laboratory!
Defining 'elderly scientist' as in Clarke's First Law.
'Hazards of Prophecy: The Failure of Imagination'. In the collection. Profiles of the Future: An Enquiry into the Limits of the Possible (1962, rev. 1973), 14-15.
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In the 1920s, there was a dinner at which the physicist Robert W. Wood was asked to respond to a toast … “To physics and metaphysics.” Now by metaphysics was meant something like philosophy—truths that you could get to just by thinking about them. Wood took a second, glanced about him, and answered along these lines: The physicist has an idea, he said. The more he thinks it through, the more sense it makes to him. He goes to the scientific literature, and the more he reads, the more promising the idea seems. Thus prepared, he devises an experiment to test the idea. The experiment is painstaking. Many possibilities are eliminated or taken into account; the accuracy of the measurement is refined. At the end of all this work, the experiment is completed and … the idea is shown to be worthless. The physicist then discards the idea, frees his mind (as I was saying a moment ago) from the clutter of error, and moves on to something else. The difference between physics and metaphysics, Wood concluded, is that the metaphysicist has no laboratory.
In 'Wonder and Skepticism', Skeptical Enquirer (Jan-Feb 1995), 19, No. 1.
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In the 1940s when I did my natural sciences degree in zoology it was very much laboratory-based. … I was not keen on the idea of spending the rest of my life in the lab. I also don’t think I would have been particularly good at it. I don't think I have as analytical a mind or the degree of application that one would need to become a first-rate research scientist.
From interview with Michael Bond, 'It’s a Wonderful Life', New Scientist (14 Dec 2002), 176, No. 2373, 48.
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In the laboratory there are no fustian ranks, no brummagem aristocracies; the domain of Science is a republic, and all its citizens are brothers and equals, its princes of Monaco and its stonemasons of Cromarty meeting, barren of man-made gauds and meretricious decorations, upon the one majestic level!
'Three Thousand Years Among the Microbes.' In Mark Twain and John Sutton Tuckey (ed.), Which Was the Dream? and Other Symbolic Writings of the Later Years (1966), 446
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In the world of science different levels of esteem are accorded to different kinds of specialist. Mathematicians have always been eminently respectable, and so are those who deal with hard lifeless theories about what constitutes the physical world: the astronomers, the physicists, the theoretical chemists. But the more closely the scientist interests himself in matters which are of direct human relevance, the lower his social status. The real scum of the scientific world are the engineers and the sociologists and the psychologists. Indeed, if a psychologist wants to rate as a scientist he must study rats, not human beings. In zoology the same rules apply. It is much more respectable to dissect muscle tissues in a laboratory than to observe the behaviour of a living animal in its natural habitat.
From transcript of BBC radio Reith Lecture (12 Nov 1967), 'A Runaway World', on the bbc.co.uk website.
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In the X-ray laboratory we are exposed, not only to the direct action of the rays, but to the effects of ionized air. This may be proved by hanging a charged silk tassel anywhere in the room. It will suddenly collapse when the current is turned on through the focus tube.
In 'Protection in X-Ray Work', Archives of the Roentgen Ray (July 1905), 10, No. 2, 38. [Note that this concern for protection, written in 1905, comes within 10 years of the discovery of X-Rays in 1895. —Webmaster]
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In view of the kind of matter we work with, it will never be possible to avoid little laboratory explosions.
Letter to Carl Jung, 18 Jun 1909. Quoted in William McGuire (ed.), The Freud-Jung Letters: The Correspondence between Sigmund Freud and C. G. Jung (1974), 235.
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It [the Euglena] is a perfect laboratory in itself, and it will act and react upon the water and the matters contained therein; converting them into new compounds resembling its own substance, and at the same time giving up portions of its own substance which have become effete.
From Address (22 Jul 1854) delivered at St. Martin’s Hall, published as a pamphlet (1854), 8, and collected in 'Educational Value of Natural History Sciences', Lay Sermons, Addresses, and Reviews (1870), 75.
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It amounts to a truism to say that progress in the practical arts of medicine in any of its branches, whether preventive or curative, only comes from the growth of accurate knowledge as it accumulates in the laboratories and studies of the various sciences.
From Norman Lockyer Lecture delivered before the British Science Guild (19 Nov 1929), 'Medical Research: The Tree and the Fruit', in The British Medical Journal (30 Nov 1929), Vol. 2, No. 3595, 995.
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It has today occurred to me that an amplifier using semiconductors rather than vacuum is in principle possible.
Laboratory notebook (29 Dec 1939).
In Michael Dudley Sturge , Statistical and Thermal Physics (2003), 251.
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It is very different to make a practical system and to introduce it. A few experiments in the laboratory would prove the practicability of system long before it could be brought into general use. You can take a pipe and put a little coal in it, close it up, heat it and light the gas that comes out of the stem, but that is not introducing gas lighting. I'll bet that if it were discovered to-morrow in New York that gas could be made out of coal it would be at least five years before the system would be in general use.
From the New York Herald (30 Jan 1879), as cited in Leslie Tomory, 'Building the First Gas Network, 1812-1820', Technology and Culture (Jan 2011), 52, No. 1, 75-102.
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It is well known that theoretical physicists cannot handle experimental equipment; it breaks whenever they touch it. Pauli was such a good theoretical physicist that something usually broke in the lab whenever he merely stepped across the threshold. A mysterious event that did not seem at first to be connected with Pauli's presence once occurred in Professor J. Franck's laboratory in Göttingen. Early one afternoon, without apparent cause, a complicated apparatus for the study of atomic phenomena collapsed. Franck wrote humorously about this to Pauli at his Zürich address and, after some delay, received an answer in an envelope with a Danish stamp. Pauli wrote that he had gone to visit Bohr and at the time of the mishap in Franck's laboratory his train was stopped for a few minutes at the Göttingen railroad station. You may believe this anecdote or not, but there are many other observations concerning the reality of the Pauli Effect!
From Thirty Years That Shook Physics: The Story of Quantum Theory (1966), 64. Note the so-called Pauli Effect is merely anecdotal to provide humor about supposed parapsychology phenomena in coincidences involving Pauli; it should not be confused with scientifically significant Pauli Exclusion Principle.
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It must be admitted that science has its castes. The man whose chief apparatus is the differential equation looks down upon one who uses a galvanometer, and he in turn upon those who putter about with sticky and smelly things in test tubes. But all of these, and most biologists too, join together in their contempt for the pariah who, not through a glass darkly, but with keen unaided vision, observes the massing of a thundercloud on the horizon, the petal as it unfolds, or the swarming of a hive of bees. And yet sometimes I think that our laboratories are but little earthworks which men build about themselves, and whose puny tops too often conceal from view the Olympian heights; that we who work in these laboratories are but skilled artisans compared with the man who is able to observe, and to draw accurate deductions from the world about him.
The Anatomy of Science (1926), 170- 1.
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It seems to me that there is a good deal of ballyhoo about scientific method. I venture to think that the people who talk most about it are the people who do least about it. Scientific method is what working scientists do, not what other people or even they themselves may say about it. No working scientist, when he plans an experiment in the laboratory, asks himself whether he is being properly scientific, nor is he interested in whatever method he may be using as method.
In Reflections of a Physicist (1955), 81.
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It will, perhaps appear probable, that one of the great laboratories of nature for cleaning and purifying the air of our atmosphere is placed in the substance of the leaves, and put in action by the influence of the light.
In Tobias George Smollett (ed.), 'Experiments Upon Vegetables', The Critical Review, Or, Annals of Literature (1779), 48, 336.
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It’s becoming clear that in a sense the cosmos provides the only laboratory where sufficiently extreme conditions are ever achieved to test new ideas on particle physics. The energies in the Big Bang were far higher than we can ever achieve on Earth. So by looking at evidence for the Big Bang, and by studying things like neutron stars, we are in effect learning something about fundamental physics.
From editted transcript of BBC Radio 3 interview, collected in Lewis Wolpert and Alison Richards, A Passion For Science (1988), 33.
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It's hard to imagine anything more difficult to study than human sexuality, on every level from the technical to the political. One has only to picture monitoring orgasm in the lab to begin to grasp the challenge of developing testing techniques that are thorough and precise, yet respectful.
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Kohn's Second Law: An experiment is reproducible until another laboratory tries to repeat it
In Dr. N Sreedharan, Quotations of Wit and Wisdom (2007), 24
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Laboratory and discovery are related terms. Do away with laboratories, and the physical sciences will be become the image of the sterility of death.
Laboratoires et découvertes sont des termes corrélatifs. Supprimez les laboratoires, les sciences physiques deviendront l’image de la stérilité et de la mort.
In article 'The Budget of Science', Revue des Cours Scientifiques (1 Feb 1868) and published as a pamphlet, Some Reflections on Science in France. As translated in Patrice Debré and Elborg Forster (trans.), Louis Pasteur (2000), 143. Original French quote in René Vallery-Radot, La Vie de Pasteur (1900), 215. Note: Pasteur was fighting for a new laboratory building, but funding had been withdrawn—yet many millions were being spent to build an opera house. The full article, which was scorching, had been first sent to the newspaper, Moniteur in early Jan 1868, but it was declined as too politically controversial. Napoleon III was notified, and he was sympathetic. Other translations include: “Laboratories and discoveries are correlative terms. If you suppress laboratories, physical science will become stricken with barrenness and death.” In René Vallery-Radot and Mrs R. L. Devonshire (trans.) The Life of Pasteur (1902), 199.
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Lectures with demonstrations are certainly valuable—more valuable than the lectures with text-books alone. Yet analyzing the object itself is infinitely more valuable than to watch the results exposed by another. Wrestling with the part which is being studied, handling it and viewing it from all sides, and tabulating and classifying the parts worked out, give us the greatest reward. All this can be accomplished by practical laboratory work. If we can make the student work thoroughly and carefully, a great result is achieved. It makes of him an artist, an actor, an expert, not a dilettante. He is upon the stage, not in the audience.
As quoted from a paper by Mall (1896), in Florence R. Sabin, Franklin Paine Mall: The Story of a Mind. (1934), 142.
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Liebig taught the world two great lessons. The first was that in order to teach chemistry it was necessary that students should be taken into a laboratory. The second lesson was that he who is to apply scientific thought and method to industrial problems must have a thorough knowledge of the sciences. The world learned the first lesson more readily than it learned the second.
Ira Remsen, Address to the Industrial Chemistry Society, Glasgow (1910). Quoted in Frederick Hutton Getman, The Life of Ira Remsen (1980), 121-122.
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Like thousands of other boys, I had a little chemical laboratory in our cellar and think that some of our friends thought me a bit crazy.
Quoted in 'Langmuir Winner Stumped Einstein”, New York Times (23 Aug 1931), N2.
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Live in the serene peace of laboratories and libraries.
Advice to young scientists at celebration for Pasteur's 70th birthday, Sorbonne (27 Dec 1892). Nature (1893), 47, 205. Also quoted in Émile Duclaux, translated by Erwin F. Smith and Florence Hedges, Pasteur: The History of a Mind (1920), xxii.
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Lord Kelvin had, in a manner hardly and perhaps never equalled before, except by Archimedes, the power of theorizing on the darkest, most obscure, and most intimate secrets of Nature, and at the same time, and almost in the same breath, carrying out effectively and practically some engineering feat, or carrying to a successful issue some engineering invention. He was one of the leaders in the movement which has compelled all modern engineers worthy of the name to be themselves men not merely of practice, but of theory, to carry out engineering undertakings in the spirit of true scientific inquiry and with an eye fixed on the rapidly growing knowledge of the mechanics of Nature, which can only be acquired by the patient work of physicists and mathematicians in their laboratories and studies.
In Speech (May 1921) to the Institute of Civil Engineers, to award the newly created Kelvin Medal. As quoted in Sarah Knowles Bolton, 'Lord Kelvin', Famous Men of Science (1889, Revised Ed. 1926), 316-317.
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Many of the things that have happened in the laboratory have happened in ways it would have been impossible to foresee, but not impossible to plan for in a sense. I do not think Dr. Whitney deliberately plans his serendipity but he is built that way; he has the art—an instinctive way of preparing himself by his curiosity and by his interest in people and in all kinds of things and in nature, so that the things he learns react on one another and thereby accomplish things that would be impossible to foresee and plan.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 355.
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May every young scientist remember … and not fail to keep his eyes open for the possibility that an irritating failure of his apparatus to give consistent results may once or twice in a lifetime conceal an important discovery.
Commenting on the discovery of thoron gas because one of Rutherford’s students had found his measurements of the ionizing property of thorium were variable. His results even seemed to relate to whether the laboratory door was closed or open. After considering the problem, Rutherford realized a radioactive gas was emitted by thorium, which hovered close to the metal sample, adding to its radioactivity—unless it was dissipated by air drafts from an open door. (Thoron was later found to be argon.)
In Barbara Lovett Cline, Men Who Made a New Physics (1987), 21.
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Microbiology Lab - Staph Only
Anonymous
Thomas F. Shubnell, Greatest Jokes of the Century Book 2 (2008), 90.
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Much as I admired the elegance of physical theories, which at that time geology wholly lacked, I preferred a life in the woods to one in the laboratory.
From J. Tuzo Wilson, 'Early Days in University Geophysics', Ann. Rev. Earth Planet Sci. (1982), 10, 4.
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No Geologist worth anything is permanently bound to a desk or laboratory, but the charming notion that true science can only be based on unbiased observation of nature in the raw is mythology. Creative work, in geology and anywhere else, is interaction and synthesis: half-baked ideas from a bar room, rocks in the field, chains of thought from lonely walks, numbers squeezed from rocks in a laboratory, numbers from a calculator riveted to a desk, fancy equipment usually malfunctioning on expensive ships, cheap equipment in the human cranium, arguments before a road cut.
An Urchin in the Storm (1988), 98.
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Obviously we biologists should fit our methods to our materials. An interesting response to this challenge has been employed particularly by persons who have entered biology from the physical sciences or who are distressed by the variability in biology; they focus their research on inbred strains of genetically homogeneous laboratory animals from which, to the maximum extent possible, variability has been eliminated. These biologists have changed the nature of the biological system to fit their methods. Such a bold and forthright solution is admirable, but it is not for me. Before I became a professional biologist, I was a boy naturalist, and I prefer a contrasting approach; to change the method to fit the system. This approach requires that one employ procedures which allow direct scientific utilization of the successful long-term evolutionary experiments which are documented by the fascinating diversity and variability of the species of animals which occupy the earth. This is easy to say and hard to do.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 232.
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On the terrace of the Pepiniere, the 150 pupils of the Institut Chemique talk chemistry as they leave the auditoria and the laboratory. The echoes of the magnificent public garden of the city of Nancy make the words reverberate; coupling, condensation, grignardization. Moreover, their clothes stay impregnated with strong and characteristic odours; we follow the initiates of Hermes by their scent. In such an environment, how is it possible not to be productive?
Charles Courtot, 'Notice sur la vie de Victor Grignard', Bulletin Societé Chemie, 1936, 3, 1445. Trans. in Mary Jo Nye, Science in the Provinces (1986),184.
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One indicator of Ernest Lawrence’s influence is the fact that I am the eighth member of his laboratory staff to receive the highest award that can come to a scientist—the Nobel Prize.
From Nobel Banquet Speech (10 Dec 1968). Collected in Wilhelm Odelberg (ed.), Les Prix Nobel en 1968 (1969).
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Our job is to keep everlastingly at research and experiment, to adapt our laboratories to production as soon as practicable, to let no new improvement in flying and flying equipment pass us by.
End of Boeing’s quote, inscribed on his memorial at the Boeing Developmental Center, Tukwila, WA, as given in Mike Lombardi, 'Historical Perspective: 50 years at the Leading Edge', Boeing Frontiers (Aug 2009), 9.
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Our laboratory work involved close contact with many non-clinical scientists. Sir Peter Medawar, 1960 Nobel Laureate, was a frequent visitor to our lab and to the hospital. He once commented, after visiting an early renal transplant patient, that it was the first time he had been in a hospital ward.
In Tore Frängsmyr and Jan E. Lindsten (eds.), Nobel Lectures: Physiology Or Medicine: 1981-1990 (1993), 556.
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Perhaps the earliest memories I have are of being a stubborn, determined child. Through the years my mother has told me that it was fortunate that I chose to do acceptable things, for if I had chosen otherwise no one could have deflected me from my path. ... The Chairman of the Physics Department, looking at this record, could only say 'That A- confirms that women do not do well at laboratory work'. But I was no longer a stubborn, determined child, but rather a stubborn, determined graduate student. The hard work and subtle discrimination were of no moment.
Autobiography, Nobel Foundation
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Put off your imagination, as you put off your overcoat, when you enter the laboratory. But put it on again, as you put on your overcoat, when you leave.
Attributed.
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Remsen never wore his hat inside the door for he had much the same respect for his laboratory that most of us have for a church.
Anonymous
Quoting an unnamed former student of Remsen, speaking of his original laboratory at Johns Hopkins University in Dalton Hall on Little Ross Street, Baltimore, Maryland. In F.H. Getman The Life of Ira Remsen (1940), 68.
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Scientists today are hampered by their low social and economic status. Long gone is the respect and independence given to Lavoisier, Darwin, Faraday, Maxwell, Perkin, Curie and Einstein. Hardly any laboratory scientist anywhere is as free as a good writer can be. Indeed I suspect that the only scientists we know well are those who can write entertaining books; the real contributors to knowledge are mostly unknown.
In The Revenge of Gaia: Earth’s Climate Crisis & The Fate of Humanity (2006, 2007), 93.
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Since an organism is inseparable from its environment, any person who attempts to understand an organism’s distribution must keep constantly in mind that the item being studied is neither a stuffed skin, a pickled specimen, nor a dot on a map. It is not even the live organism held in the hand, caged in a laboratory, or seen in the field. It is a complex interaction between a self-sustaining physicochemical system and the environment. An obvious corollary is that to know the organism it is necessary to know its environment.
From 'The role of physiology in the distribution of terrestrial vertebrates', collected in C.L. Hubbs (ed.), Zoogeography: Publ. 51 (1958), 83.
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Sodium thymonucleate fibres give two distinct types of X-ray diagram … [structures A and B]. The X-ray diagram of structure B (see photograph) shows in striking manner the features characteristic of helical structures, first worked out in this laboratory by Stokes (unpublished) and by Crick, Cochran and Vand2. Stokes and Wilkins were the first to propose such structures for nucleic acid as a result of direct studies of nucleic acid fibres, although a helical structure had been previously suggested by Furberg (thesis, London, 1949) on the basis of X-ray studies of nucleosides and nucleotides.
While the X-ray evidence cannot, at present, be taken as direct proof that the structure is helical, other considerations discussed below make the existence of a helical structure highly probable.
From Rosalind Franklin and R. G. Gosling,'Molecular Configuration in Sodium Thymonucleate', Nature (25 Apr 1953), 171, No. 4356, 740.
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Sometimes my courage fails me and I think I ought to stop working, live in the country and devote myself to gardening. But I am held by a thousand bonds, and I don't know when I shall be able to arrange things otherwise. Nor do I know whether, even by writing scientific books, I could live without the laboratory.
Letter to her sister Bronya, September 1927. In Eve Curie, Madame Curie (1938), 388.
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Speaking one day to Monsieur de Buffon, on the present ardor of chemical inquiry, he affected to consider chemistry but as cookery, and to place the toils of the laboratory on the footing with those of the kitchen. I think it, on the contrary, among the most useful of sciences, and big with future discoveries for the utility and safety of the human race.
Letter to Rev. James Madison (Paris, 19 Jul 1788). In Thomas Jefferson and John P. Foley (ed.), The Jeffersonian Cyclopedia (1900), 135. From H.A. Washington, The Writings of Thomas Jefferson (1853-54). Vol 2, 431.
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Students using astrophysical textbooks remain essentially ignorant of even the existence of plasma concepts, despite the fact that some of them have been known for half a century. The conclusion is that astrophysics is too important to be left in the hands of astrophysicists who have gotten their main knowledge from these textbooks. Earthbound and space telescope data must be treated by scientists who are familiar with laboratory and magnetospheric physics and circuit theory, and of course with modern plasma theory.
[Lamenting the traditional neglect of plasma physics]
Quoted in Anthony L. Peratt, 'Dean of the Plasma Dissidents', Washington Times, supplement: The World and I (May 1988),197.
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That's all right, but you still haven't found out what makes the bath water gargle when you pull the plug out.
[Remark to a scientist who was showing him around the National Physical Laboratory.]
Quoted in Laura Ward, Foolish Words: The Most Stupid Words Ever Spoken (2003), 30.
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The American Cancer Society's position on the question of a possible cause-effect relationship between cigarette smoking and lung cancer is:
1. The evidence to date justifies suspicion that cigarette smoking does, to a degree as yet undetermined, increase the likelihood of developing cancer of the lung.
2. That available evidence does not constitute irrefutable proof that cigarette smoking is wholly or chiefly or partly responsible for lung cancer.
3. That the evidence at hand calls for the extension of statistical and laboratory studies designed to confirm or deny a causual relationship between cigarette smoking and lung cancer.
4. That the society is committed to furthering such intensified investigation as its resources will permit.
Conclusions of statement after a meeting of the ACS board of directors in San Francisco (17 Mar 1954). Quoted in 'Tobacco Industry Denies Cancer Tie'. New York Times (14 Apr 1954), 51.
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The automatic computing engine now being designed at N.P.L. [National Physics Laboratory] is atypical large scale electronic digital computing machine. In a single lecture it will not be possible to give much technical detail of this machine, and most of what I shall say will apply equally to any other machine of this type now being planned. From the point of view of the mathematician the property of being digital should be of greater interest than that of being electronic. That it is electronic is certainly important because these machines owe their high speed to this, and without the speed it is doubtful if financial support for their construction would be forthcoming. But this is virtually all that there is to be said on that subject. That the machine is digital however has more subtle significance. It means firstly that numbers are represented by sequences of digits which can be as long as one wishes. One can therefore work to any desired degree of accuracy. This accuracy is not obtained by more careful machining of parts, control of temperature variations, and such means, but by a slight increase in the amount of equipment in the machine.
Lecture to the London Mathematical Society, 20 February 1947. Quoted in B. E. Carpenter and R. W. Doran (eds.), A. M. Turing's Ace Report of 1946 and Other Papers (1986), 106.
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The bottom of the sea is the great laboratory, where loose materials are mineralized and formed into stone, the atmosphere is the region where stones are decomposed, and again resolved into earth.
In The Works of John Playfair: Vol. 1: Illustrations of the Huttonian Theory of the Earth (1822), 109.
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The chances for favorable serendipity are increased if one studies an animal that is not one of the common laboratory species. Atypical animals, or preparations, force one to use non-standard approaches and non-standard techniques, and even to think nonstandard ideas. My own preference is to seek out species which show some extreme of adaptation. Such organisms often force one to abandon standard methods and standard points of view. Almost inevitably they lead one to ask new questions, and most importantly in trying to comprehend their special and often unusual adaptations one often serendipitously stumbles upon new insights.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 234.
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The comforting, if spurious, precision of laboratory results has the same appeal as the lifebelt to the weak swimmer.
Anonymous
Lancet (1981) 1, 539-40 (1981)
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The experienced observer does more than merely report and recite. He guides the eager student to an understanding of the earth. He may chart the scientist’s steep, barren road of sober observation and strict deduction, or the artist’s gentle road of contemplation and empathy. And, finally, he may point out his own unique way, the path of the initiated, which leads him from the laboratories and libraries to the meadows and flower gardens of the living earth.
In 'Prologue', Conversation with the Earth (1954), 7. As translated by E.B. Garside from Gespräch mit der Erde (1947).
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The faith of scientists in the power and truth of mathematics is so implicit that their work has gradually become less and less observation, and more and more calculation. The promiscuous collection and tabulation of data have given way to a process of assigning possible meanings, merely supposed real entities, to mathematical terms, working out the logical results, and then staging certain crucial experiments to check the hypothesis against the actual empirical results. But the facts which are accepted by virtue of these tests are not actually observed at all. With the advance of mathematical technique in physics, the tangible results of experiment have become less and less spectacular; on the other hand, their significance has grown in inverse proportion. The men in the laboratory have departed so far from the old forms of experimentation—typified by Galileo's weights and Franklin's kite—that they cannot be said to observe the actual objects of their curiosity at all; instead, they are watching index needles, revolving drums, and sensitive plates. No psychology of 'association' of sense-experiences can relate these data to the objects they signify, for in most cases the objects have never been experienced. Observation has become almost entirely indirect; and readings take the place of genuine witness.
Philosophy in a New Key; A Study in Inverse the Symbolism of Reason, Rite, and Art (1942), 19-20.
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The future generation of scientists will be a sorry lot if the best teachers leave the academic circles for more lucrative positions in military or industrial laboratories.
In 'The Physicist Returns from the War', The Atlantic Monthly (Oct 1945), 176, No. 4, 108. Collected in 'Physics: A Physicist Surveys the Scene', American Thought 1947 (1947), 326.
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The injurious agent in cigarettes comes principally from the burning paper wrapper. The substance thereby formed is called “acrolein.” It has a violent action on the nerve centers, producing degeneration of the cells of the brain, which is quite rapid among boys. Unlike most narcotics, this degeneration is permanent and uncontrollable. I employ no person who smokes cigarettes.
[From the Laboratory of Thomas A. Edison, Orange, N.J., April 26, 1914.]
Quoted in Henry Ford, The Case Against the Little White Slaver (1914), Vol. 1, 5.
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The laboratory routine, which involves a great deal of measurement, filing, and tabulation, is either my lifeline or my chief handicap, I hardly know which.
(1949). Epigraph in Susan Elizabeth Hough, Richter's Scale: Measure of an Earthquake, Measure of a Man (2007), 62.
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The laboratory was an unattractive half basement and low ceilinged room with an inner dark room for the galvanometer and experimental animals. It was dark, crowded with equipment and uninviting. Into it came patients for electrocardiography, dogs for experiments, trays with coffee and buns for lunch. It was hot and dusty in summer and cold in winter. True a large fire burnt brightly in the winter but anyone who found time to warm his backside at it was not beloved by [Sir Thomas] Lewis. It was no good to try and look out of the window for relaxation, for it was glazed with opaque glass. The scientific peaks were our only scenery, and it was our job to try and find the pathways to the top.
'Tribute to Sir Thomas Lewis', University College Hospital Magazine (1955), 40, 71.
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The laboratory work was the province of Dr Searle, an explosive, bearded Nemesis who struck terror into my heart. If one made a blunder one was sent to ‘stand in the corner’ like a naughty child. He had no patience with the women students. He said they disturbed the magnetic equipment, and more than once I heard him shout ‘Go and take off your corsets!’ for most girls wore these garments then, and steel was beginning to replace whalebone as a stiffening agent. For all his eccentricities, he gave us excellent training in all types of precise measurement and in the correct handling of data.
In Cecilia Payne-Gaposchkin: An Autobiography and Other Recollections (1996), 116.
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The landed classes neglected technical education, taking refuge in classical studies; as late as 1930, for example, long after Ernest Rutherford at Cambridge had discovered the atomic nucleus and begun transmuting elements, the physics laboratory at Oxford had not been wired for electricity. Intellectuals neglect technical education to this day.
Describing C.P. Snow’s observations on the neglect of technical education in Visions of Technology (1999), 23.
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The last person who left the lab will be the one held responsible for everything that goes wrong.
Anonymous
Found in The NIH Catalyst (May-June 2003), 11, No. 3, 8, as part of list 'A Scientist’s Dozen,' cited as “culled and adapted…from a variety of sources” by Howard Young.
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The laws of physics and chemistry must be the same in a crucible as in the larger laboratory of Nature.
The Natural History of Igneous Rocks (1909), 282.
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The lives of scientists, considered as Lives, almost always make dull reading. For one thing, the careers of the famous and the merely ordinary fall into much the same pattern, give or take an honorary degree or two, or (in European countries) an honorific order. It could be hardly otherwise. Academics can only seldom lead lives that are spacious or exciting in a worldly sense. They need laboratories or libraries and the company of other academics. Their work is in no way made deeper or more cogent by privation, distress or worldly buffetings. Their private lives may be unhappy, strangely mixed up or comic, but not in ways that tell us anything special about the nature or direction of their work. Academics lie outside the devastation area of the literary convention according to which the lives of artists and men of letters are intrinsically interesting, a source of cultural insight in themselves. If a scientist were to cut his ear off, no one would take it as evidence of a heightened sensibility; if a historian were to fail (as Ruskin did) to consummate his marriage, we should not suppose that our understanding of historical scholarship had somehow been enriched.
'J.B.S: A Johnsonian Scientist', New York Review of Books (10 Oct 1968), reprinted in Pluto's Republic (1982), and inThe Strange Case of the Spotted Mice and Other Classic Essays on Science (1996), 86.
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The mathematics of cooperation of men and tools is interesting. Separated men trying their individual experiments contribute in proportion to their numbers and their work may be called mathematically additive. The effect of a single piece of apparatus given to one man is also additive only, but when a group of men are cooperating, as distinct from merely operating, their work raises with some higher power of the number than the first power. It approaches the square for two men and the cube for three. Two men cooperating with two different pieces of apparatus, say a special furnace and a pyrometer or a hydraulic press and new chemical substances, are more powerful than their arithmetical sum. These facts doubtless assist as assets of a research laboratory.
Quoted from a speech delivered at the fiftieth anniversary of granting of M.I.T's charter, in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 352.
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The Mecca of the biological world.
Describing the Naples Biological Station, one of the world’s leading marine laboratories in the world.
The Biological Stations of Europe (1910), 9.
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The mind is a vagrant thing ... Thinking is not analogous to a person working in a laboratory who invents something on company time.
Answering criticism that the book for which he won a Pulitzer Prize was written in the years he had been employed at the Smithsonian. He specified that did not write on the premises there, but only at home outside of working hours.
Quoted by Barbara Gamarekian in 'Working Profile: Daniel J. Boorstin. Helping the Library of Congress Fulfill Its Mission', New York Times (8 Jul 1983), B6.
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The modern research laboratory can be a large and complicated social organism.
How to Win the Nobel Prize: An Unexpected Life in Science (2004), xii.
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The night before Easter Sunday of that year (1920) I awoke, turned on the light, and jotted down a few notes on a tiny slip of thin paper. Then I fell asleep again. It occurred to me at six o’clock in the morning that during the night I had written down something most important, but I was unable to decipher the scrawl. The next night, at three o’clock, the idea returned. It was the design of an experiment to determine whether the hypothesis of chemical transmission that I had uttered seventeen years ago was correct. I got up immediately, went to the laboratory, and performed a simple experiment on a frog heart according to the nocturnal design. I have to describe this experiment briefly since its results became the foundation of the theory of chemical transmission of the nervous impulse. The hearts of two frogs were isolated, the first with its nerves, the second without. Both hearts were attached to Straub cannulas filled with a little Ringer solution. The vagus nerve of the first heart was stimulated for a few minutes. Then the Ringer solution that had been in the first heart during the stimulation of the vagus was transferred to the second heart. It slowed and its beats diminished just as if its vagus had been stimulated. Similarly, when the accelerator nerve was stimulated and the Ringer from this period transferred, the second heart speeded up and its beats increased. These results unequivocally proved that the nerves do not influence the heart directly but liberate from their terminals specific chemical substances which, in their turn, cause the well-known modifications of the function of the heart characteristic of the stimulation of its nerves.
'An Autobiographic Sketch', Perspectives in Biology and Medicine (1960), 4, 17.
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The plant cell, like the animal cell, is a type of laboratory of cellular tissues that organize themselves and develop within its innermost substance; its imperforate walls, to judge from our strongest magnifying instruments, have the property of drawing out by aspiration from the ambient liquid the elements necessary for its elaboration. They thus have the property of acting as a sorter, of admitting certain substances and preventing the passage of others, and consequently of separating the elements of certain combinations in order to admit only a portion of them.
As quoted in article Marc Klein,'François-Vincent Raspail', in Charles Coulston Gillispie (ed.), Dictionary of Scientific Biography (1975). Vol.11, 300.
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The public image of the scientist tends to be that of a magician, occasionally benevolent, though more often giving rise to disastrous inventions, or perhaps that of a man shutting himself into a laboratory and, in his lonely way, playing with retorts and test tubes, or perhaps leaning back in a comfortable armchair in a darkened room and thinking.
In 'Why Scientists Talk', collected in John Wolfenden, Hermann Bondi, et al., The Languages of Science: A Survey of Techniques of Communication (1963), 35.
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The stars are laboratories in which the evolution of matter proceeds in the direction of large molecules.
In Teilhard de Chardin and Bernard Wall (trans.), The Phenomenon of Man (1959, 2008), 50. Originally published in French as Le Phénomene Humain (1955).
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The stories of Whitney’s love for experimenting are legion. At one time he received a letter asking if insects could live in a vacuum. Whitney took the letter to one of the members of his staff and asked the man if he cared to run an experiment on the subject. The man replied that there was no point in it, since it was well established that life could not exist without a supply of oxygen. Whitney, who was an inveterate student of wild life, replied that on his farm he had seen turtles bury themselves in mud each fall, and, although the mud was covered with ice and snow for months, emerge again in the spring. The man exclaimed, “Oh, you mean hibernation!” Whitney answered, “I don’t know what I mean, but I want to know if bugs can live in a vacuum.”
He proceeded down the hall and broached the subject to another member of the staff. Faced with the same lack of enthusiasm for pursuing the matter further, Whitney tried another illustration. “I’ve been told that you can freeze a goldfish solidly in a cake of ice, where he certainly can’t get much oxygen, and can keep him there for a month or two. But if you thaw him out carefully he seems none the worse for his experience.” The second scientist replied, “Oh, you mean suspended animation.” Whitney once again explained that his interest was not in the terms but in finding an answer to the question.
Finally Whitney returned to his own laboratory and set to work. He placed a fly and a cockroach in a bell jar and removed the air. The two insects promptly keeled over. After approximately two hours, however, when he gradually admitted air again, the cockroach waved its feelers and staggered to its feet. Before long, both the cockroach and the fly were back in action.
'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 357-358.
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The sum of human happiness would not necessarily be reduced if for ten years every physical and chemical laboratory were closed and the patient and resourceful energy displayed in them transferred to the lost art of getting on together and finding the formula for making both ends meet in the scale of human life.
In a speech to the British Association for the Advancement of Science, Leeds, September 4, 1927.
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The true laboratory is the mind, where behind illusions we uncover the laws of truth.
Quoted in India Today (Apr 2008), 33, No 16, as cited on webpage of Dhirubhai Ambani Institute of Information and Communication Technology.
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The value of fundamental research does not lie only in the ideas it produces. There is more to it. It affects the whole intellectual life of a nation by determining its way of thinking and the standards by which actions and intellectual production are judged. If science is highly regarded and if the importance of being concerned with the most up-to-date problems of fundamental research is recognized, then a spiritual climate is created which influences the other activities. An atmosphere of creativity is established which penetrates every cultural frontier. Applied sciences and technology are forced to adjust themselves to the highest intellectual standards which are developed in the basic sciences. This influence works in many ways: some fundamental students go into industry; the techniques which are applied to meet the stringent requirements of fundamental research serve to create new technological methods. The style, the scale, and the level of scientific and technical work are determined in pure research; that is what attracts productive people and what brings scientists to those countries where science is at the highest level. Fundamental research sets the standards of modern scientific thought; it creates the intellectual climate in which our modern civilization flourishes. It pumps the lifeblood of idea and inventiveness not only into the technological laboratories and factories, but into every cultural activity of our time. The case for generous support for pure and fundamental science is as simple as that.
In 'Why Pure Science?' in Bulletin of the Atomic Scientists, 1965.
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The world makes a messy laboratory for ecologists, a cauldron of five million interacting species. Or is it fifty million? Ecologists do not actually know.
In Chaos: Making a New Science (1985, 1987), 59.
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The X-ray spectrometer opened up a new world. It proved to be a far more powerful method of analysing crystal structure…. One could examine the various faces of a crystal in succession, and by noting the angles at which and the intensity with which they reflected the X-rays, one could deduce the way in which the atoms were arranged in sheets parallel to these faces. The intersections of these sheets pinned down the positions of the atoms in space.… It was like discovering an alluvial gold field with nuggets lying around waiting to be picked up.… It was a glorious time when we worked far into every night with new worlds unfolding before us in the silent laboratory.
In The History of X-ray Analysis (1943), 9.
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There has been a very large number of mutations discovered in the laboratory races of Drosophila melanogaster Meigen…. It…would be of considerable interest to get an idea of how these mutations compare with the differences between wild species of Drosophila.
In The North American Species of Drosophila (1921), 1.
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There is no short cut from chemical laboratory to clinic, except one that passes too close to the morgue.
Anonymous
American Medical Association (1929) as quoted in Arabella Melville and Colin Johnson , Cured to Death: The Effects of Prescription Drugs (1982).
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There is only one thing worse than coming home from the lab to a sink full of dirty dishes, and that is not going to the lab at all!
Quoted in Giorgio Giacomelli, Maurizio Spurio and Jamal Eddine Derkaoui, Cosmic Radiations: From Astronomy to Particle Physics (2001), 344. by - Science - 2001
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Think, for a moment, of a cheetah, a sleek, beautiful animal, one of the fastest on earth, which roams freely on the savannas of Africa. In its natural habitat, it is a magnificent animal, almost a work of art, unsurpassed in speed or grace by any other animal. Now, think of a cheetah that has been captured and thrown into a miserable cage in a zoo. It has lost its original grace and beauty, and is put on display for our amusement. We see only the broken spirit of the cheetah in the cage, not its original power and elegance. The cheetah can be compared to the laws of physics, which are beautiful in their natural setting. The natural habitat of the laws of physics is a higher-dimensional space-time. However, we can only measure the laws of physics when they have been broken and placed on display in a cage, which is our three-dimensional laboratory. We only see the cheetah when its grace and beauty have been stripped away.
In Hyperspace by Michio Kaku (1994).
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This notion that “science” is something that belongs in a separate compartment of its own, apart from everyday life, is one that I should like to challenge. We live in a scientific age; yet we assume that knowledge of science is the prerogative of only a small number of human beings, isolated and priest-like in their laboratories. This is not true. It cannot be true. The materials of science are the materials of life itself. Science is part of the reality of living; it is the what, the how, and the why of everything in our experience. It is impossible to understand man without understanding his environment and the forces that have molded him physically and mentally.
Address upon receiving National Book Award at reception, Hotel Commodore, New York (27 Jan 1952). As cited in Linda Lear, Rachel Carson: Witness for Nature (1997), 218-219.
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This whole period was a golden age of immunology, an age abounding in important synthetic discoveries all over the world, a time we all thought it was good to be alive. We, who were working on these problems, all knew each other and met as often as we could to exchange ideas and hot news from the laboratory.
In Memoir of a Thinking Radish: An Autobiography (1986), 135.
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Time... is an essential requirement for effective research. An investigator may be given a palace to live in, a perfect laboratory to work in, he may be surrounded by all the conveniences money can provide; but if his time is taken from him he will remain sterile.
Quoted in S. Benison, A. C. Barger and E. L. Wolfe, Walter B Cannon: The Life and Times of a Young Scientist (1987), 253.
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To be creative, scientists need libraries and laboratories and the company of other scientists; certainly a quiet and untroubled life is a help. A scientist's work is in no way deepened or made more cogent by privation, anxiety, distress, or emotional harassment. To be sure, the private lives of scientists may be strangely and even comically mixed up, but not in ways that have any special bearing on the nature and quality of their work. If a scientist were to cut off an ear, no one would interpret such an action as evidence of an unhappy torment of creativity; nor will a scientist be excused any bizarrerie, however extravagant, on the grounds that he is a scientist, however brilliant.
In Advice to a Young Scientist (1979), 40.
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To each of us life is an experiment in Nature’s laboratory, and she tests and tries us in a thousand ways, using us and improving us if we serve her turn, ruthlessly dispensing with us if we do not.
In 'The Evolution of the Idea of Experiment in Medicine', Transactions of the Congress of American Physicians and Surgeons. Seventh Triennial Session (1907), 7.
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To Monsieur Lavoisier by appointment. Madame Lavoisier, a lively, sensible, scientific lady, had prepared a dejuné Anglois of tea and coffee, but her conversation on Mr. Kirwan’s Essay on Phlogiston, which she is translating from the English, and on other subjects, which a woman of understanding, that works with her husband in his laboratory, knows how to adorn, was the best repast.
Entry for 16 Oct 1787. In Arthur Young, Travels in France During the Years, 1787, 1788 and 1789 (1792), 64.
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To our senses, the elements are four
and have ever been, and will ever be
for they are the elements of life, of poetry, and of perception,
the four Great Ones, the Four Roots, the First Four
of Fire and the Wet, Earth and the wide Air of the World.
To find the other many elements, you must go to the laboratory
and hunt them down.
But the four we have always with us, they are our world.
Or rather, they have us with them.
'The Four', David Herbert Lawrence, The Works of D.H. Lawrence (1994), 593.
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Tungsten, X-rays, and Coolidge form a trinity that has left an indelible impression upon our life and times. The key word in this triad is Coolidge, for his work brought the element tungsten from laboratory obscurity to the central role of the industrial stage and gave the X-ray a central role in the progress of medicine throughout the world.
In National Academy of Sciences, Biographical Memoirs, Vol. 53, 141.
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Unless our laboratory results are to give us artificialities, mere scientific curiosities, they must be subjected to interpretation by gradual re-approximation to conditions of life.
'Psychology and Social Practice', The Psychological Review, 1900, 7, 119.
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Using material ferried up by rockets, it would be possible to construct a “space station” in ... orbit. The station could be provided with living quarters, laboratories and everything needed for the comfort of its crew, who would be relieved and provisioned by a regular rocket service. (1945)
In 'Can Rocket Stations Give Worldwide Coverage?', Wireless World (Oct 1945). Quoted and cited in Arthur C. Clarke, Greetings, Carbon-Based Bipeds!: Collected Essays, 1934-1998, 22. Also quoted in 'Hazards of Communication Satellites', Bulletin of the Atomic Scientists (May 1961), Vol. 17, No. 5, 181, by John R. Pierce Pierce, who then commented, “Clarke thought in terms of manned space stations; today these seem very remote.”
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We have been forced to admit for the first time in history not only the possibility of the fact of the growth and decay of the elements of matter. With radium and with uranium we do not see anything but the decay. And yet, somewhere, somehow, it is almost certain that these elements must be continuously forming. They are probably being put together now in the laboratory of the stars. ... Can we ever learn to control the process. Why not? Only research can tell.
'The Significance of Radium,' an address delivered (in connection with the presentation of a gram of radium to Madame Curie) at the National Museum, Washington, D.C. (25 May 1921). In Science (1921), 54, No. 1383, 1921. In Rodney P. Carlisle, Scientific American Inventions and Discoveries (2004), 375.
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We have seen that a proton of energy corresponding to 30,000 volts can effect the transformation of lithium into two fast α-particles, which together have an energy equivalent of more than 16 million volts. Considering the individual process, the output of energy in the transmutation is more than 500 times greater than the energy carried by the proton. There is thus a great gain of energy in the single transmutation, but we must not forget that on an average more than 1000 million protons of equal energy must be fired into the lithium before one happens to hit and enter the lithium nucleus. It is clear in this case that on the whole the energy derived from transmutation of the atom is small compared with the energy of the bombarding particles. There thus seems to be little prospect that we can hope to obtain a new source of power by these processes. It has sometimes been suggested, from analogy with ordinary explosives, that the transmutation of one atom might cause the transmutation of a neighbouring nucleus, so that the explosion would spread throughout all the material. If this were true, we should long ago have had a gigantic explosion in our laboratories with no one remaining to tell the tale. The absence of these accidents indicates, as we should expect, that the explosion is confined to the individual nucleus and does not spread to the neighbouring nuclei, which may be regarded as relatively far removed from the centre of the explosion.
The Transmutation of the Atom (1933), 23-4
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We spend long hours discussing the curious situation that the two great bodies of biological knowledge, genetics and embryology, which were obviously intimately interrelated in development, had never been brought together in any revealing way. An obvious difficulty was that the most favorable organisms for genetics, Drosophila as a prime example, were not well suited for embryological study, and the classical objects of embryological study, sea urchins and frogs as examples, were not easily investigated genetically. What might we do about it? There were two obvious approaches: one to learn more about the genetics of an embryologically favourable organism, the other to better understand the development of Drosophila. We resolved to gamble up to a year of our lives on the latter approach, this in Ephrussi’s laboratory in Paris which was admirably equipped for tissue culture, tissue or organ transplantation, and related techniques.
In 'Recollections', Annual Review of Biochemistry, 1974, 43, 6.
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We’re all of us guinea pigs in the laboratory of God. Humanity is just a work in progress.
Dialog by Gypsy in Camino Real (1953). American Blues: Five Short Plays (1976), 60.
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What happens if a big asteroid hits Earth? Judging from realistic simulations involving a sledge hammer and a common laboratory frog, we can assume it will be pretty bad.
In Geoff Tibballs, The Mammoth Book of Zingers, Quips, and One-Liners (2004), 502.
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What Pasteur and Langmuir believed—and what history has shown—is that both epidemiologists and laboratory scientists can make independent discoveries that have significant scientific impact, but collaboration across these disciplines has a synergistic effect, yielding public health data that are stronger than either discipline can provide alone
These words are not quoted directly from Walter R. Dowdle, but are a paraphrase of an explanation of an epigraph attributed to him: [“Alexander Langmuir was quoted in the early 1960s instructing incoming Epidemic Intelligence Service (EIS) officers that the only need for the laboratory in an outbreak investigation was to ‘prove their conclusions were right.’— Walter R. Dowdle (2011)”], to Chap. 9, M. Shannon Keckler, Reynolds M. Salerno, and Michael W. Shaw, 'Optimizing Epidemiology–Laboratory Collaborations' in Centers for Disease Control and Prevention, The CDC Field Epidemiology Manual (2018), 188. These authors paraphrased and expanded on a footnoted reference for which Dowdle was the corresponding author: “Langmuir’s point was not to denigrate the laboratory but to emphasize the power of an investigation based on a solid clinical case definition and established field epidemiologic principles,” in Walter R. Dowdle, Leonard W. Mayer, Karen K. Steinberg, Neelam D. Ghiya and Tanja Popovic (co-authors), 'CDC Laboratory Contributions to Public Health', Morbidity and Mortality Weekly Report, Supplements (7 Oct 2011), 60, 27. [This epigraph was complemented by another: “Sans laboratoires les savants sont des soldats sans armes.”. Without laboratories men of science are soldiers without arms. — Louis Pasteur (1923).]
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What was Freud’s Galapagos, what species fluttered what kinds of wings before his searching eyes? It has often been pointed out derisively: his creative laboratory was the neurologist’s office, the dominant species hysterical ladies.
The First Psychoanalyst (1957), 83.
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When chemists have brought their knowledge out of their special laboratories into the laboratory of the world, where chemical combinations are and have been through all time going on in such vast proportions,—when physicists study the laws of moisture, of clouds and storms, in past periods as well as in the present,—when, in short, geologists and zoologists are chemists and physicists, and vice versa,—then we shall learn more of the changes the world has undergone than is possible now that they are separately studied.
Geological Sketches (1866), 73.
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When I think of Miss Sabin’s work in the Medical School it seems to me that she has been an ideal university professor. Successful in teaching, productive in research, conscientious and cooperative in all routine duties of an administrative character. Following the admonition of Pasteur she has chosen to dwell in the serene peace of the laboratory and library, and in this environment has given her time and best energies to the work belonging to her position.
As quoted in Vincent T. Andriole, 'Florence Rena Sabin—Teacher, Scientist, Citizen', Journal of the History of Medicine and Allied Sciences (Jul 1959), 14, No. 3, (July 1959), 325. Cited as from W. H. Howell, 'Presentation to the University of the Portrait of Dr. Florence Rena Sabin', Bulletin of Johns Hopkins Hospital (1920), 31, 151.
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When it was first proposed to establish laboratories at Cambridge, Todhunter, the mathematician, objected that it was unnecessary for students to see experiments performed, since the results could be vouched for by their teachers, all of them of the highest character, and many of them clergymen of the Church of England.
In The Scientific Outlook (1931, 2009), 49.
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When one studies strongly radioactive substances special precautions must be taken if one wishes to be able to take delicate measurements. The various objects used in a chemical laboratory and those used in a chemical laboratory, and those which serve for experiments in physics, become radioactive in a short time and act upon photographic plates through black paper. Dust, the air of the room, and one’s clothes all become radioactive.
Notebook entry. In Eve Curie, Madame Curie: a Biography by Eve Curie (1937, 2007), 196.
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While working with staphylococcus variants a number of culture-plates were set aside on the laboratory bench and examined from time to time. In the examinations these plates were necessarily exposed to the air and they became contaminated with various micro-organisms. It was noticed that around a large colony of a contaminating mould the staphylococcus colonies became transparent and were obviously undergoing lysis. Subcultures of this mould were made and experiments conducted with a view to ascertaining something of the properties of the bacteriolytic substance which had evidently been formed in the mould culture and which had diffused into the surrounding medium. It was found that broth in which the mould had been grown at room temperature for one or two weeks had acquired marked inhibitory, bacteriocidal and bacteriolytic properties to many of the more common pathogenic bacteria.
'On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. Influenzae', British Journal of Experimental Pathology, 1929, 10, 226.
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Why, only last term we sent a man who had never been in a laboratory in his life as a senior Science Master to one of our leading public schools. He came [to our agency] wanting to do private coaching in music. He’s doing very well, I believe.
In Decline and Fall (1928), 1962 edn., 25.
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With a greater knowledge of what are called hormones, i.e., the chemical messengers in our blood, it will be possible to control growth. We shall escape the absurdity of growing a whole chicken in order to eat the breast or wing, by growing these parts separately under a suitable medium.
In 'Fifty Years Hence', Popular Mechanics Magazine (Mar 1932), 57, No. 3, 397,
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Within the last five or six years [from 1916], from a common wild species of fly, the fruit fly, Drosophila ampelophila, which we have brought into the laboratory, have arisen over a hundred and twenty-five new types whose origin is completely known.
In A Critique of the Theory of Evolution (1916), 60.
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You are urgently warned against allowing yourself to be influenced in any way by theories or by other preconceived notions in the observation of phenomena, the performance of analyses and other determinations.
Laboratory Rules at Munich. Quoted by M. Bergmann, 'Fischer', in Bugge's Das Buch der Grosse Chemiker. Trans. Joseph S. Froton, Contrasts in Scientific Style: Research Groups in the Chemical and Biomedical Sciences (1990), 172.
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You know, I am sorry for the poor fellows that haven’t got labs to work in.
Remark addressed to H.R. Robinson, recorded by Robinson in 'Personal Reminiscences of the Manchester Period', collected in J.B. Birks, Rutherford at Manchester (1962), 77.
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You want to find out what the facts are, and what you do is in that respect similar to what a laboratory technician does. Possibly philosophers would look on us mathematicians the same way as we look on the technicians, if they dared.
In I Want to be a Mathematician: an Automathography (1985), 321.
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Young men, … Live in the serene peace of laboratories and libraries. Say to yourselves first: “What have I done for my instruction?” and, as you gradually advance, “What have I done for my country?”
Acceptance speech (27 Dec 1892) when awarded a 70th birthday commemorative medal by the Academy of Sciences in the great theatre of the Sorbonne, as translated in René Vallery-Radot and Mrs R.L. Devonshire (trans.), The Life of Pasteur (1902), Vol. 2, 297-298. Pasteur addressed an audience that included “deep masses of students” and “boys from the lycées.”
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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Ernest Rutherford
James Chadwick
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William Harvey
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Carl Gauss
Paul Feyerabend
- 90 -
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Lise Meitner
Charles Babbage
Ibn Khaldun
Euclid
Ralph Emerson
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Andre Ampere
Winston Churchill
- 80 -
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Bible
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Louis Pasteur
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Jean Lamarck
- 70 -
Samuel Morse
John Wheeler
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Robert Fulton
Pierre Laplace
Humphry Davy
Thomas Edison
Lord Kelvin
Theodore Roosevelt
Carolus Linnaeus
- 60 -
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Immanuel Kant
Martin Fischer
Robert Boyle
Karl Popper
Paul Dirac
Avicenna
James Watson
William Shakespeare
- 50 -
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Nikola Tesla
Rachel Carson
Max Planck
Henry Adams
Richard Dawkins
Werner Heisenberg
Alfred Wegener
John Dalton
- 40 -
Pierre Fermat
Edward Wilson
Johannes Kepler
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Giordano Bruno
JJ Thomson
Thomas Kuhn
Leonardo DaVinci
Archimedes
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- 30 -
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Richard Feynman
James Hutton
Alexander Fleming
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Benjamin Franklin
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- 20 -
Carl Sagan
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Francis Bacon
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- 10 -
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